65280 ÷ 4 = 16320 R0
Alright, let's work through the division of 65280 by 4 step by step.

Step 1:
4 goes into 6 1 times with a remainder of 2.
Write down 1 as next digit of of the result. 
Result so far: 1
Subtract 4 from 6 to get 2.
Bring next digit (5) of the dividend behind the 2 and repeat the process: 25 / 4

Step 2:
4 goes into 25 6 times with a remainder of 1.
Write down 6 as next digit of of the result. 
Result so far: 16
Subtract 24 from 25 to get 1.
Bring next digit (2) of the dividend behind the 1 and repeat the process: 12 / 4

Step 3:
4 goes into 12 3 times with a remainder of 0.
Write down 3 as next digit of of the result. 
Result so far: 163
Subtract 12 from 12 to get 0.
Bring next digit (8) of the dividend behind the 0 and repeat the process: 8 / 4

Step 4:
4 goes into 8 2 times with a remainder of 0.
Write down 2 as next digit of of the result. 
Result so far: 1632
Subtract 8 from 8 to get 0.
Bring next digit (0) of the dividend behind the 0 and repeat the process: 0 / 4

Step 5:
4 goes into 0 0 times with a remainder of 0.
Write down 0 as next digit of of the result. 
Result so far: 16320
Subtract 0 from 0 to get 0.

The final result is 16320 with a remainder of 0.