Okay, let's tackle this math problem. We're starting with 58481592 and subtracting 15100301.

Step 1: We'll start by subtracting the digit 1 and the borrow 0 from 2 in column 1 and get 1.
1 is the first digit of our result.

Step 2: We'll start by subtracting the digit 0 and the borrow 0 from 9 in column 2 and get 9.
9 is the next digit of our result.

Step 3: We'll start by subtracting the digit 3 and the borrow 0 from 5 in column 3 and get 2.
2 is the next digit of our result.

Step 4: We'll start by subtracting the digit 0 and the borrow 0 from 1 in column 4 and get 1.
1 is the next digit of our result.

Step 5: We'll start by subtracting the digit 0 and the borrow 0 from 8 in column 5 and get 8.
8 is the next digit of our result.

Step 6: We'll start by subtracting the digit 1 and the borrow 0 from 4 in column 6 and get 3.
3 is the next digit of our result.

Step 7: We'll start by subtracting the digit 5 and the borrow 0 from 8 in column 7 and get 3.
3 is the next digit of our result.

Step 8: We'll start by subtracting the digit 1 and the borrow 0 from 5 in column 8 and get 4.
4 is the next digit of our result.

So, 58481592 - 15100301 = 43381291.