Okay, let's tackle this math problem. We're starting with 33481 and subtracting 33222.

Step 1: We'll start by subtracting the digit 2 and the borrow 0 from 1 in column 1 and get -1.
We add -1 to 10 and get 9 as the first digit of the result.

Step 2: We'll start by subtracting the digit 2 and the borrow 1 from 8 in column 2 and get 5.
5 is the next digit of our result.

Step 3: We'll start by subtracting the digit 2 and the borrow 0 from 4 in column 3 and get 2.
2 is the next digit of our result.

Step 4: We'll start by subtracting the digit 3 and the borrow 0 from 3 in column 4 and get 0.
0 is the next digit of our result.

Step 5: We'll start by subtracting the digit 3 and the borrow 0 from 3 in column 5 and get 0.
0 is the next digit of our result.

So, 33481 - 33222 = 259.