Let's get this math done. We have 265578 and 14359, and we're going to subtract the second number from the first.

Step 1: We'll start by subtracting the digit 9 and the borrow 0 from 8 in column 1 and get -1.
We add -1 to 10 and get 9 as the first digit of the result.

Step 2: We'll start by subtracting the digit 5 and the borrow 1 from 7 in column 2 and get 1.
1 is the next digit of our result.

Step 3: We'll start by subtracting the digit 3 and the borrow 0 from 5 in column 3 and get 2.
2 is the next digit of our result.

Step 4: We'll start by subtracting the digit 4 and the borrow 0 from 5 in column 4 and get 1.
1 is the next digit of our result.

Step 5: We'll start by subtracting the digit 1 and the borrow 0 from 6 in column 5 and get 5.
5 is the next digit of our result.

Step 6: We'll start by subtracting the digit 0 and the borrow 0 from 2 in column 6 and get 2.
2 is the next digit of our result.

So, 265578 - 14359 = 251219.