No problem, let's work through this together. We're starting with 599282 and are subtracting 56250 from it.

Step 1: We'll start by subtracting the digit 0 and the borrow 0 from 2 in column 1 and get 2.
2 is the first digit of our result.

Step 2: We'll start by subtracting the digit 5 and the borrow 0 from 8 in column 2 and get 3.
3 is the next digit of our result.

Step 3: We'll start by subtracting the digit 2 and the borrow 0 from 2 in column 3 and get 0.
0 is the next digit of our result.

Step 4: We'll start by subtracting the digit 6 and the borrow 0 from 9 in column 4 and get 3.
3 is the next digit of our result.

Step 5: We'll start by subtracting the digit 5 and the borrow 0 from 9 in column 5 and get 4.
4 is the next digit of our result.

Step 6: We'll start by subtracting the digit 0 and the borrow 0 from 5 in column 6 and get 5.
5 is the next digit of our result.

So, 599282 - 56250 = 543032.