Alright, let's solve this problem step by step. We have 38349 and 6297, and we're subtracting the second number from the first.

Step 1: We'll start by subtracting the digit 7 and the borrow 0 from 9 in column 1 and get 2.
2 is the first digit of our result.

Step 2: We'll start by subtracting the digit 9 and the borrow 0 from 4 in column 2 and get -5.
We add -5 to 10 and get 5 as the next digit of the result.

Step 3: We'll start by subtracting the digit 2 and the borrow 1 from 3 in column 3 and get 0.
0 is the next digit of our result.

Step 4: We'll start by subtracting the digit 6 and the borrow 0 from 8 in column 4 and get 2.
2 is the next digit of our result.

Step 5: We'll start by subtracting the digit 0 and the borrow 0 from 3 in column 5 and get 3.
3 is the next digit of our result.

So, 38349 - 6297 = 32052.