Let's get this math done. We have 59151 and 37003, and we're going to subtract the second number from the first.

Step 1: We'll start by subtracting the digit 3 and the borrow 0 from 1 in column 1 and get -2.
We add -2 to 10 and get 8 as the first digit of the result.

Step 2: We'll start by subtracting the digit 0 and the borrow 1 from 5 in column 2 and get 4.
4 is the next digit of our result.

Step 3: We'll start by subtracting the digit 0 and the borrow 0 from 1 in column 3 and get 1.
1 is the next digit of our result.

Step 4: We'll start by subtracting the digit 7 and the borrow 0 from 9 in column 4 and get 2.
2 is the next digit of our result.

Step 5: We'll start by subtracting the digit 3 and the borrow 0 from 5 in column 5 and get 2.
2 is the next digit of our result.

So, 59151 - 37003 = 22148.