Alright, ready to do some subtraction? We're taking 29149 and subtracting 6850 from it.

Step 1: We'll start by subtracting the digit 0 and the borrow 0 from 9 in column 1 and get 9.
9 is the first digit of our result.

Step 2: We'll start by subtracting the digit 5 and the borrow 0 from 4 in column 2 and get -1.
We add -1 to 10 and get 9 as the next digit of the result.

Step 3: We'll start by subtracting the digit 8 and the borrow 1 from 1 in column 3 and get -8.
We add -8 to 10 and get 2 as the next digit of the result.

Step 4: We'll start by subtracting the digit 6 and the borrow 1 from 9 in column 4 and get 2.
2 is the next digit of our result.

Step 5: We'll start by subtracting the digit 0 and the borrow 0 from 2 in column 5 and get 2.
2 is the next digit of our result.

So, 29149 - 6850 = 22299.