42546 ÷ 4 = 10636 R2
No problem, we've got 42546 and 4 for the division.

Step 1:
4 goes into 4 1 times with a remainder of 0.
Write down 1 as next digit of of the result. 
Result so far: 1
Subtract 4 from 4 to get 0.
Bring next digit (2) of the dividend behind the 0 and repeat the process: 2 / 4

Step 2:
4 goes into 2 0 times with a remainder of 2.
Write down 0 as next digit of of the result. 
Result so far: 10
Subtract 0 from 2 to get 2.
Bring next digit (5) of the dividend behind the 2 and repeat the process: 25 / 4

Step 3:
4 goes into 25 6 times with a remainder of 1.
Write down 6 as next digit of of the result. 
Result so far: 106
Subtract 24 from 25 to get 1.
Bring next digit (4) of the dividend behind the 1 and repeat the process: 14 / 4

Step 4:
4 goes into 14 3 times with a remainder of 2.
Write down 3 as next digit of of the result. 
Result so far: 1063
Subtract 12 from 14 to get 2.
Bring next digit (6) of the dividend behind the 2 and repeat the process: 26 / 4

Step 5:
4 goes into 26 6 times with a remainder of 2.
Write down 6 as next digit of of the result. 
Result so far: 10636
Subtract 24 from 26 to get 2.

The final result is 10636 with a remainder of 2.