Okay, we are tasked with adding 435 and 4645. Let's begin!

Step 1: We'll start by adding the digits 5 & 5 in column 1 and get 10.
We'll write down the last digit 0 and carry the 1 to the next column.

Step 2: We'll start by adding the digits 3 & 4 in column 2 and get 8.

Step 3: We'll start by adding the digits 4 & 6 in column 3 and get 10.
We'll write down the last digit 0 and carry the 1 to the next column.

Step 4: We'll start by adding the digits 0 & 4 in column 4 and get 5.

So, 435 + 4645 = 5080.

