Sure thing! We've got 42227 and 26593, and we're going to subtract the second number from the first.

Step 1: We'll start by subtracting the digit 3 and the borrow 0 from 7 in column 1 and get 4.
4 is the first digit of our result.

Step 2: We'll start by subtracting the digit 9 and the borrow 0 from 2 in column 2 and get -7.
We add -7 to 10 and get 3 as the next digit of the result.

Step 3: We'll start by subtracting the digit 5 and the borrow 1 from 2 in column 3 and get -4.
We add -4 to 10 and get 6 as the next digit of the result.

Step 4: We'll start by subtracting the digit 6 and the borrow 1 from 2 in column 4 and get -5.
We add -5 to 10 and get 5 as the next digit of the result.

Step 5: We'll start by subtracting the digit 2 and the borrow 1 from 4 in column 5 and get 1.
1 is the next digit of our result.

So, 42227 - 26593 = 15634.