We look at the division of 45228421 by 451 
Let's see how many times 451 fits into 45228421.

On to step 1:
451 can be fit into 4 0 times, resulting in a remainder of 4.
Put 0 as the next digit of the answer. 
Result so far: 0.0
Subtracting 0 from 4 leaves us with 4.
Take the next digit (5) from the dividend and append it to 4, then repeat: 45 / 451

Let's proceed to step 2:
If we divide 45 by 451, we get 0 and a remainder of 45.
Put 0 as the next digit of the answer. 
Result so far: 0.0
Subtract 0 from 45 to get 45.
Include the next digit (2) from the dividend after 45, then repeat: 452 / 451

Let's proceed to step 3:
When dividing 452 by 451, we get 1 with a remainder of 1.
The next digit of our result is 1. 
Result so far: 1.0
If we take 451 away from 452, we end up with 1.
Fetch the next digit (2) from the dividend, attach it to 1 and continue: 12 / 451

On to step 4:
When dividing 12 by 451, we get 0 with a remainder of 12.
The number 0 becomes the next digit in our result. 
Result so far: 10.0
Deduct 0 from 12 and we're left with 12.
Grab the next digit (8) from the dividend, add it to 12, then carry on: 128 / 451

Going ahead to step 5:
When dividing 128 by 451, we get 0 with a remainder of 128.
The number 0 becomes the next digit in our result. 
Result so far: 100.0
Subtract 0 from 128 to get 128.
Bring next digit (4) of the dividend behind the 128 and repeat the process: 1284 / 451

Going ahead to step 6:
If we divide 1284 by 451, we get 2 and a remainder of 382.
The next digit of our result is 2. 
Result so far: 1002.0
Deduct 902 from 1284 and we're left with 382.
Grab the next digit (2) from the dividend, add it to 382, then carry on: 3822 / 451

Step 7:
If we divide 3822 by 451, we get 8 and a remainder of 214.
Use 8 as the next digit of our solution. 
Result so far: 10028.0
Subtracting 3608 from 3822 leaves us with 214.
Fetch the next digit (1) from the dividend, attach it to 214 and continue: 2141 / 451

Advancing to step 8:
The number 451 fits into 2141 4 times, leaving a remainder of 337.
Write down 4 as next digit of the result. 
Result so far: 100284.0
The remainder is 337 after subtracting 1804 from 2141.
Since there are no more digits in the dividend, we add a zero to the remainder making it 3370, and continue the process.

Moving on to step 9:
451 can be fit into 3370 7 times, resulting in a remainder of 213.
Use 7 as the next digit of our solution. 
Result so far: 100284.7
Subtracting 3157 from 3370 leaves us with 213.
Since there are no more digits in the dividend, we add a zero to the remainder making it 2130, and continue the process.

On to step 10:
451 goes into 2130 4 times with a remainder of 326.
Put 4 as the next digit of the answer. 
Result so far: 100284.74
Deduct 1804 from 2130 and we're left with 326.
Since there are no more digits in the dividend, we add a zero to the remainder making it 3260, and continue the process.

Step 11:
When dividing 3260 by 451, we get 7 with a remainder of 103.
Record the quotient 7 as the next digit in the result. 
Result so far: 100284.747
If we take 3157 away from 3260, we end up with 103.
Since there are no more digits in the dividend, we add a zero to the remainder making it 1030, and continue the process.

Going ahead to step 12:
451 goes into 1030 2 times with a remainder of 128.
Put 2 as the next digit of the answer. 
Result so far: 100284.7472
Deduct 902 from 1030 and we're left with 128.
Since there are no more digits in the dividend, we add a zero to the remainder making it 1280, and continue the process.

Moving on to step 13:
451 can be fit into 1280 2 times, resulting in a remainder of 378.
The number 2 becomes the next digit in our result. 
Result so far: 100284.74722
Subtracting 902 from 1280 leaves us with 378.
Since there are no more digits in the dividend, we add a zero to the remainder making it 3780, and continue the process.

The quotient of the division is 100284.74722, and the remainder is 0.000378.