Got it! So, we have 451696 and 99343, and we'll subtract the latter from the former.

Step 1: We'll start by subtracting the digit 3 and the borrow 0 from 6 in column 1 and get 3.
3 is the first digit of our result.

Step 2: We'll start by subtracting the digit 4 and the borrow 0 from 9 in column 2 and get 5.
5 is the next digit of our result.

Step 3: We'll start by subtracting the digit 3 and the borrow 0 from 6 in column 3 and get 3.
3 is the next digit of our result.

Step 4: We'll start by subtracting the digit 9 and the borrow 0 from 1 in column 4 and get -8.
We add -8 to 10 and get 2 as the next digit of the result.

Step 5: We'll start by subtracting the digit 9 and the borrow 1 from 5 in column 5 and get -5.
We add -5 to 10 and get 5 as the next digit of the result.

Step 6: We'll start by subtracting the digit 0 and the borrow 1 from 4 in column 6 and get 3.
3 is the next digit of our result.

So, 451696 - 99343 = 352353.