OK, let's do this. We've got 508995 and 6269, and we're subtracting the second number from the first.

Step 1: We'll start by subtracting the digit 9 and the borrow 0 from 5 in column 1 and get -4.
We add -4 to 10 and get 6 as the first digit of the result.

Step 2: We'll start by subtracting the digit 6 and the borrow 1 from 9 in column 2 and get 2.
2 is the next digit of our result.

Step 3: We'll start by subtracting the digit 2 and the borrow 0 from 9 in column 3 and get 7.
7 is the next digit of our result.

Step 4: We'll start by subtracting the digit 6 and the borrow 0 from 8 in column 4 and get 2.
2 is the next digit of our result.

Step 5: We'll start by subtracting the digit 0 and the borrow 0 from 0 in column 5 and get 0.
0 is the next digit of our result.

Step 6: We'll start by subtracting the digit 0 and the borrow 0 from 5 in column 6 and get 5.
5 is the next digit of our result.

So, 508995 - 6269 = 502726.