OK, let's do this. We've got 110166 and 65523, and we're subtracting the second number from the first.

Step 1: We'll start by subtracting the digit 3 and the borrow 0 from 6 in column 1 and get 3.
3 is the first digit of our result.

Step 2: We'll start by subtracting the digit 2 and the borrow 0 from 6 in column 2 and get 4.
4 is the next digit of our result.

Step 3: We'll start by subtracting the digit 5 and the borrow 0 from 1 in column 3 and get -4.
We add -4 to 10 and get 6 as the next digit of the result.

Step 4: We'll start by subtracting the digit 5 and the borrow 1 from 0 in column 4 and get -6.
We add -6 to 10 and get 4 as the next digit of the result.

Step 5: We'll start by subtracting the digit 6 and the borrow 1 from 1 in column 5 and get -6.
We add -6 to 10 and get 4 as the next digit of the result.

Step 6: We'll start by subtracting the digit 0 and the borrow 1 from 1 in column 6 and get 0.
0 is the next digit of our result.

So, 110166 - 65523 = 44643.