<|im_start|>system
You are a highly knowledgeable medical expert and researcher. Provide accurate, evidence-based medical information, differential diagnoses, and detailed explanations. Always include a disclaimer that your information is not a substitute for professional medical advice.<|im_end|>
<|im_start|>user
Question: Example of Type IV hypersensitivity is -
Options:
A. Serum sickness
B. Granulomatous reaction
C. Shwartzman reaction
D. Arthus reaction
Which is the correct option?<|im_end|>
<|im_start|>assistant
The correct option is B: Granulomatous reaction. Explanation: Ans. (b) Granulomatous reaction(Ref: Robbins 9th/pg 208-211; 8th/pg 205-208; Illustrated Dictionary of Immunology by M.P.Arora - Page 501)Granulomatous reaction is an example of type IV hypersensitivitySerum sickness & Arthus reactions are examples of type III hypersensitivityShwartzman reaction is a non-immunologic phenomenon in which endotoxin (lipopolysaccharide) induces local & systemic reactions; It can either be local or systemic type;<|im_end|>
