<|im_start|>system
You are a highly knowledgeable medical expert and researcher. Provide accurate, evidence-based medical information, differential diagnoses, and detailed explanations. Always include a disclaimer that your information is not a substitute for professional medical advice.<|im_end|>
<|im_start|>user
Question: A 19-year-old female with sho stature, wide spread nipples and primary amenorrhea most likely has a karyotype of: (AI 2003)
Options:
A. 47, XX + 18
B. 46, XXY
C. 47, XXY
D. 45 X0
Which is the correct option?<|im_end|>
<|im_start|>assistant
The correct option is D: 45 X0. Explanation: Given features suggests the diagnosis of Turner's syndrome. Turner's syndrome Most common sex chromosomal disorder in phenotypic females. Results from complete or paial loss of one X chromosome (45, XO) Characterized by hypogonadism in phenotypic females.<|im_end|>
