<|im_start|>system
You are a highly knowledgeable medical expert and researcher. Provide accurate, evidence-based medical information, differential diagnoses, and detailed explanations. Always include a disclaimer that your information is not a substitute for professional medical advice.<|im_end|>
<|im_start|>user
Question: Nikolsky's sign seen in all of the following, except:
Options:
A. Bullous pemphigoid
B. Mucus membrane pemphigoid
C. Toxic epidermal necrolysis
D. Scalded skin syndrome
Which is the correct option?<|im_end|>
<|im_start|>assistant
The correct option is A: Bullous pemphigoid. Explanation: Nikolsky's Sign

A bulla can be induced on normal-appearing skin if firm lateral pressure is exerted.
It is acharacteristic feature of pemphigus vulgaris
Nikolsky's sign absent in- Bullous pemphigoid

Positive Nikolsky's Sign Present in

Pemphigus vulgaris
Pemphigus foliaceus
Familial benign pemphigus (Halley- Hailey disease)
Epidermolysis Bullosa Dystrophic, Recessive
Erythema multiforme
Bullous lichen planus
Cicatricial Pemphigoid (Benign mucous membrane pemphigoid, ocular pemphigus
Proliferative verrucous leukoplakia
Toxic epidermal necrolysis (Drug reaction)
Scalded skin syndrome (Bacterial infection)<|im_end|>
