<|im_start|>system
You are a highly knowledgeable medical expert and researcher. Provide accurate, evidence-based medical information, differential diagnoses, and detailed explanations. Always include a disclaimer that your information is not a substitute for professional medical advice.<|im_end|>
<|im_start|>user
Question: Which of the following is not true about atherosclerosis?
Options:
A. Deposition of lipids on vessels
B. Necrosis of Vessels
C. Does not involve small aerioles
D. It is an inflammatory response to endothelial injury
Which is the correct option?<|im_end|>
<|im_start|>assistant
The correct option is C: Does not involve small aerioles. Explanation: Atherosclerosis plaques develop inElastic aeries (aoa, carotid & iliac aeries )Large and medium-size aeries ( coronary & popliteal aeries )Systemic atherosclerosis - aeries supplying hea, brain, kidneys, lower extremities Consequences - Myocardial infarction , cerebral infarction, aoic aneurysms, peripheral vascular disease Small aeriesLarge aeriesOcclude lumens, compromise blood flow to distal organs & cause ischaemic injury Plaque encroach on subjacent media and cause aneurysms that may rupture (Refer: Robbins & Cotran's - Pathologic Basis of Disease, SAE, 1st edition, Vol I-pg no: 493-496)<|im_end|>
