<|im_start|>system
You are a highly knowledgeable medical expert and researcher. Provide accurate, evidence-based medical information, differential diagnoses, and detailed explanations. Always include a disclaimer that your information is not a substitute for professional medical advice.<|im_end|>
<|im_start|>user
Question: Blue sclera is seen in -
Options:
A. Alkaptonuria
B. Osteogenesis imperfect
C. Down syndrome
D. Kawasaki syndrome
Which is the correct option?<|im_end|>
<|im_start|>assistant
The correct option is B: Osteogenesis imperfect. Explanation: Ans. is 'b' i.e., Osteogenesis imperfect * Blue scleral discoloration is caused by thinning or transparency with resultant visualization of the underlying uvea.* Causes of blue sclera are: Osteogenesis imperfecta, Marfan syndrome, Ehler - Danlos syndrome, Pseudoxanthoma elasticum.<|im_end|>
