<|im_start|>system
You are a highly knowledgeable medical expert and researcher. Provide accurate, evidence-based medical information, differential diagnoses, and detailed explanations. Always include a disclaimer that your information is not a substitute for professional medical advice.<|im_end|>
<|im_start|>user
Question: Drug of choice for prevention of NSAID induced peptic ulcer disease is
Options:
A. H2 receptor blockers
B. Proton pump inhibitors
C. Macrolide antibiotic
D. Sucralfate
Which is the correct option?<|im_end|>
<|im_start|>assistant
The correct option is B: Proton pump inhibitors. Explanation: Ans. is 'b' i.e., Proton pump inhibitors * PPI are the DOC for peptic ulcer (gastric or duodenal), GERD, ZE syndrome, prevention of aspiratory pneumonia and NSAID induced gastric / duodenal ulcers. Note - PGE1 analogue (Misoprostol) is specific drug for prevention and treatment of NSAID induced ulcer, but DOC is PPL<|im_end|>
