Fold changes of piRNA expression levels in UTRs and CDS between Siwi-D670A and Siwi overexpressed libraries. Non-TE-derived piRNAs are similarly up-regulated across 5′ UTR (non-TE: 105 genes, TE: 274 genes), CDS (non-TE: 628 genes, TE: 811 genes), and 3′ UTR (non-TE: 126 genes, TE: 257 genes). Bonferroni-corrected P-values were calculated by Asymptotic Wilcoxon rank sum test. Fold changes of piRNA expression levels in introns (15,065 annotated regions), intergenic regions (11,124 annotated regions), and exons (10,177 annotated regions) between Siwi-D670A and Siwi overexpressed libraries. Only exon-derived piRNAs are up-regulated by Siwi-D670A overexpression, suggesting that the process is strictly cytoplasmic. Bonferroni-corrected P-values and the effect sizes (r) were calculated by Asymptotic Wilcoxon rank sum test. 