(B) The efficiency of knockdown and overexpression of LAPM-2A. PC12 cells were transiently cotransfected with LAMP-2A plasmid or LAMP-2A siRNA for 48 h. Lysates were subjected to Western blot analysis with anti-human LAMP-2A. Values are the mean±SE of three independent experiments. **P<0.01 (compared with control); ##P<0.01 (compared with Htt-552-100Q with control). 