(C, D) Targeted bisulfite-sequencing heat map showing non-conversion rates of cytosines in mitochondrial tRNA Met-CAU (C) and mitochondrial 18S rRNA (D). Each row represents one genetic strain analysed and each column represents one cytosine. Data information: In (C, D), the average of two experiments is plotted, n = 2 independent biological replicates, 10 clones sequenced per strain, per replicate. Similar effects were observed in all replicates analysed. 