(K) Representative cytometric graph of methoxy-X-O4+ labelled pvMΦ from SPF (green line), GF (yellow line) and ABX-treated (blue line) 5xFAD mice and respective WT controls (dashed lines). Quantification of percentages of methoxy-X-O4+ labelled pvMΦ are depicted. Each symbol represents one mouse. Data are presented as mean ± s.e.m. Significant differences were determined by two-way ANOVA followed by Tukey's post-hoc comparison test (*P < 0.05, ***P < 0.001). Data are representative of three independent experiments. 