D, Apoptotic assay of A549 and H358 cells treated with vehicle (DMSO), AZD 4547 (5 µM) and BI2536 (5 nM) for 48h in the presence or absence of HCQ (10 µM). Data are presented as mean ± SD (n=3). *P<0.05 and ns P＞0.05 by two-way ANOVA with Tukey's multiple comparisons test. 