Experimental design for blocking JNK/c-Jun signaling in the IMQ-induced skin inflammation model. c-Jun fl/fl, c-JunΔ/ΔCD11c-Cre, Tlr7-/- and Tlr7-/- c-JunΔ/ΔCD11c-Cre mice were treated with IMQ and JNK inhibitor SP600125 (JNKi, 15 mg/kg, i.p.) or vehicle for 5 consecutive days. Data information: Data are shown as mean ± SEM. P‐values were calculated by one-way ANOVA with Tukey Statistical significance: ns > 0.05, *P < 0.05, **P < 0.01, ***P < 0.001, **** P < 0.0001. See Appendix Table S3 for exact P‐values. 