(G) qRT-PCR measurement of IFNB1 transcripts in HEK293 cells stably expressing Flag-STING that were left unstimulated or stimulated with 2'3' cGAMP (0.1 μg/mL) for 4 h in the presence of DMSO or Palbociclib at indicated concentrations. The data shown are mean ± SEM of n=3 biological replicates. Statistical significance was determined by two-way ANOVA followed by Tukey's post hoc test. ****, P<0.0001; ns, not significant. 