A) Enrichment of APRs not protected by a specific charge in DnaK substrates, as determined by Niwa and colleagues (Niwa et al, 2012), analysed versus PureTANGO score of the APR considered. Statistical significance was determined through hypergeometric testing, with Bonferroni correction for multiple testing. *: p-value < 0.05. P-values and Pearson correlation coefficients (R2) for linear regression are indicated. 