A) Boxplots showing all-atom energetic analysis of the introduction of charged GKs into the DnaK-substrate interaction structures. The upper whiskers indicate the largest value no further than 1.5 times the Inter-Quartile Range (IQR) from the upper hinge, the lower whiskers show the smallest value at least 1.5 * IQR from the lower hinge. Notches extend 1.58 * IQR / sqrt(n) from either side of the median and represent a 95% confidence interval for the median value. Grey shaded area indicates total energy associated with the placement of GKs into substrate peptides, the remainder of the plot shows the breakdown of this total energy in into constituent energy terms. The number of replicates per box is 561. 