Detailed view of the Sir4 H‑BRCT-Esc1pS1450 peptide interaction. Sir4 H‑BRCT is displayed as orange model with residues involved in peptide binding shown as sticks (orange, atom colors). The Esc1pS1450 peptide is presented as sticks in grey (atom colors). Electrostatic interactions are highlighted with green dotted lines while main hydrophobic contacts are shown as dotted lines in black. Detailed view of the Sir4 H‑BRCT-Ty5pS1095 peptide interaction. Sir4 H‑BRCT is displayed as in (C) while the Ty5pS1095 peptide is presented as sticks in blue (atom colors). Protein-peptide interactions are labeled as in (C). Detailed view of the Sir4 H‑BRCT-Ubp10pT123 peptide interaction. Sir4 H‑BRCT is displayed as in (C) while the Ubp10pT123 peptide is presented as sticks in green (atom colors). Protein-peptide interactions are labeled as in (C). 