D Relative UPP1 mRNA expression in HCT116 cells transfected either with control (siCtrl) or UPP1-targeting (siUPP1) siRNAs and treated as indicated (NEN (N) 1.2 µM, Domperidone (D) 30 µM). Data information: data (N=3) are presented as mean (SD) and were analyzed by two -way ANOVA with Tukey post-hoc test 