(B) Genes with a |log2(FC)|>1 and p-adj<0.01 were used for hierarchical clustering. For each cluster, the gene list was uploaded on Fidea (http://circe.med.uniroma1.it/fidea/) (D'Andrea et al, 2013). The five most significant enrichment of GO (biological processes) terms are shown, and the -log10(p_value) with Bonferroni correction is shown. 