I. Isotope carbon tracing with [13C3]-lactate treatment (20mM, 24hr) in siCON or siMCT12-treated HBVPs showing the extent of downstream metabolites and incorporation rate of labeled carbons. (F-6-P : Fructose 6-phosphate, G-3-P : Glycerol-3-phosphate, Lac : Lactate, Cit : Isocitrate and aKG : α-ketoglutarate) (n=3 from independent experiments. Error bars indicate the standard error of the mean (SEM) from unpaired Student's t test. 