C) Capture-C (MCF-7hypoxia - blue; 786-O - green) at the CCND1 locus from an enhancer (red highlight) bound by HIF almost exclusively in VHL defective 786-O and showing cell-specific cis-interactions, blue highlighted region indicates region of interaction at the TSS of CCND1, green highlighted region indicates region of interaction at an enhancer 3' to the MYEOV gene. 