qRT-PCR detection of Il23p19, Il17a in total RNA isolated from the back skin of indicated mice treated with IMQ for 32 or 48h. (n = 10-21; 3-6 experiments). Data information: Data are shown as mean ± SEM. P‐values were calculated by unpaired, two-tailed t-test C) Statistical significance: ns > 0.05, *P < 0.05, **P < 0.01, ***P < 0.001, **** P < 0.0001. See Appendix Table S3 for exact P‐values. 