C The mRNA levels of Ifnb1 were measured by qRT-PCR in WT (n=3) and Akt2 KO (n=3) PEMs with Irf3 knockdown for 48 hours and VSV treatment for 6 hours. Data information: *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 and ns, not significant (P > 0.05); using two-way ANOVA test Data are from three independent experiments Error bars mean ± SEM). 