(F) Oxygen consumption rate (OCR) normalized to the amount of protein in WT, Mfn1 KO and Mfn2 KO fibroblasts. Proton leak was measured after application of oligomycin (1 μM), maximal after CCCP application (10 μM) and oligomycin (n= 3 independent experiments). Data are presented as mean ± SEM. Data information: *p<0.05, one-way ANOVA followed by Tukey's post hoc test. 