(F) rBCV biogenesis in BMMs treated with either non-targeting siNT, siRab6a/a' or siRab8a siRNAs and infected with wild type (2308) bacteria. Data are means ± SD of n=3 independent experiments, in which 100 BCVs were analyzed per experiment. Asterisks indicate statistically significant differences (P<0.05, two-way ANOVA followed by Dunnett's multiple comparisons test) compared to control (2308). 