Rotavirus RNAs have a 5′ cap but not a 3′ poly(A) tail. Its NSP3 protein (instead of PABP) binds to the 3′ end of the viral mRNA and interacts with eIF-4G directly to maintain the closed-loop RNA for the initiation of viral RNA translation and to block host mRNA circularization (Piron et al, 1998)." 