Experimental overview of the tamoxifen-inducible disruption of Il7r following generation of 2W1S-specific Th1 memory T cells. CD4creERT2 x Il7rf/f or Il7rf/f (littermate control) mice were injected i.v. with Lm-2W1S, tamoxifen administered for 4 consective days (19-21 dpi) and spleen cells harvested for ATAC-Seq 14-18 days later. 