(E) Cell proliferation assays of the PKM2 KO MCF7 cells stably transfected with shCtrl or shTMEM33 constructs (n=3). shCtrl: shControl. Data information: Data are displayed as means ± SD. Statistical significance was assessed using two-tailed Student's t-test, ∗p < 0.05 and ∗∗∗p < 0.001. 