qRT-PCR analysis of the relative Ifnb1 and Ifna4 mRNA expression levels in PICs (n≥5) and PBMCs (n≥4) (B) from WT and Akt2 KO mice Data information: *P < 0.05, **P < 0.01 and ****P < 0.0001; using unpaired t-test Data are representative of three independent experiments Error bars , mean ± SD). 