(A) Heatmap showing the differential expression of a selection of miRNAs known as "FibromiRs" in human BRAFV600E mutant melanoma cells sensitive to MAPK-targeted therapies (M229, M238, M249) and the corresponding BRAFi-resistant cells. Expression of indicated FibromiRs was evaluated by RT-qPCR; log2 (Resistant vs Parental). Expression level of AXL and MITF phenotypic markers for each resistant cell line is indicated. 