C Caspase activity in HCT116 cells either transfected with control (Ctrl), ATF4- or CHOP-targeting siRNAs and treated as indicated (NEN (N) 1.2 µM, Domperidone (D) 30 µM). Data information: Data are presented as mean (SD) and were analyzed by two-way ANOVA with Tukey post-hoc test (C (N=3), E (N=4), F (N=4). 