D) Scatterplot of differential expressed genes in CX3CR1GFP/+ and CX3CR1GFP/+;Sfrp1-/- microglia; the red line represents linear regression (slope 0.704014 p-value: < 2.2e-16 by F-test followed by Bonferroni's correction) of the differential expression, indicating response attenuation. Coloured dots represent response which are exclusive for each genotype as represented in E. 