(B) The relative mRNA expression levels of TMEM33, RNF5, MT1A and MT2A in parental and PKM2 KO MDA-MB-231 cells (n=3). Data information: Data are displayed as means ± SD. Statistical significance was assessed using two-tailed Student's t-test, ∗∗p < 0.01 and ∗∗∗p < 0.001. 