C. Volcano plot of RNA-seq data obtained from human oocytes in control and U0126 group. 'Up' and 'Down' are the upregulated and downregulated transcripts in oocytes treated with U0126. The genes with upregulation and downregulation (abs[log2FC] ≥ 1; FDR ≤ 0.05) were labeled in red and blue, respectively. 