 Figure 3 - Model fitting and classification of primary response genes. A: HEK293∆RAF1:ER cells were treated with 4OHT for constitutive induction of ERK signalling. Phosphorylation levels of ERK2 were measured with bead-based ELISA (Bio-Plex). RNA time course expression data was measured using microarrays. This data was the basis to train gene-wise model parameters. 