To Pfizer Inc.’s Management: We have examined management of Pfizer Inc.’s (“Pfizer”) assertion on page Pfizer Environmental, Social, & Governance Report 2020 (the “Report”) that Pfizer has allocated $296 million in net proceeds (the “Allocation”) from the issuance of its March 27, 2020, 2.625% Notes due April 1, 2030 (the “Sustainability Bond”) as of December 31, 2020 in accordance with the Use of Proceeds defined on pages S-6 and S-7 of the Prospectus Supplement dated March 25, 2020 (the “Prospectus Supplement”).