of employee survey respondents feel that AstraZeneca has a ‘Speak Up’ culture 9 members govern sustainability on our Sustainability Advisory Board — composed of four external experts and five Senior Executive Team (SET) members 1 of 3 Sustainability is a component of Great Place to Work, one of our three company strategic priorities 30+ performance metrics measured quarterly in the internal company scorecard 100% of active pharmaceutical ingredient discharges (API) from AstraZeneca owned sites demonstrated as safe; 94% of discharges from direct suppliers demonstrated as safe2 60% reduction in Scope 1 and 2 greenhouse gas emissions since 2015 2% reduction in our waste since 2015 20% reduction in our water use since 2015 25m+ people reached through our access programmes1 (cumulative) 46.9% women in senior middle management roles and above We recognise that several of these measures were impacted by the pandemic and may not reflect a typical trajectory.