We use a robust, integrated global substance data management system to ensure compliance and prepare notifications to regulatory authorities, including those that manage the Toxic Substances Control Act (TSCA) in the US; Registration, Evaluation, Authorization, and Restriction of Chemicals in Europe (EUREACH); the Technical Regulation of the Eurasian Economic Union (EAEU) on Safety of Chemical Products (Eurasia-REACH); the Act on the Registration and Evaluation of Chemicals in Korea (Korea AREC); the Chemical Substances Control Law in Japan; Ministry of Ecology and Environment (MEE) Order No. China; the Toxic Chemical Substance Control Act in Taiwan; and many more.