We increased the scope of our operational carbon footprint reporting in Reduce waste generation by 2% (against a 2015 baseline) to 36,760 tonnes by 2016 In 2016, our total waste was 37,923 metric tonnes, a 1% increase on 2015 Reduce water use by 2% to 4.13 million m3 (against a 2015 baseline) by 2016 In 2016, our water footprint was 3.99 million m3, a 5% reduction compared with 2015 90% of API syntheses meet resource efficiency targets at launch by 2016 100% of API syntheses (avibactam) met launch target in 2016.