The corporate governance “therapeutics” include establishment and enhancement of Board committees responsible for safety oversight; regular public disclosure of API commitment to shareholder involvement through regular dialogue regarding corporate governance; updating the employee and supplier Codes of Conduct to incorporate various enhancements and updates, including updates to more fully promote and ensure safety culture and reporting; stating the respective responsibilities of the Chief Safety Officer (CSO), the Chief Ethics and Compliance Officer (CECO), and the Boards and their committees regarding instillation of safety culture, including responsibilities for communication and reporting; providing for regular attendance and reporting by the CSO and the CECO at Board and Board committee meetings, and providing those officers with access to senior management and employees; clarification regarding the incorporation of safety, compliance, and ethics into officer compensation; enhancement of a speak-up culture for employees and Board members; and enhancement of safety training for employees and Board members.