DEA The DEA, the Federal government’s drug enforcement body, sets quotas for the number of controlled substances that manufacturers should develop Manufacturers Manufacturers develop controlled substances that are bought by distributors Distributors Distributors handle logistics and transport controlled substances based on prescriptions written by doctors and other healthcare providers Pharmacies Pharmacies and hospitals place orders with distributors for controlled substances and dispense directly to consumers Doctors Doctors prescribe medications (including controlled substances) for patients and send prescriptions to the pharmacy Patients Patients go to doctors for medical care and treatment for health concerns commitments to be a part of the solution to this crisis.