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Gout is an inflammatory disease that can cause very painful attacks. The illness is also called podagral, or colloquially “The Captain’s syndrome”. It primarily affects men, particularly over 40 years of age. Symptoms of an attack are typically manifested in the big toe or other places like swollen and extremely painful joints. Need more than pain relief “Patients with gout often suffer from great pain. Instead of preventing attacks, many doctors and patients focus on reducing the immediate pain and inflammation during the acute attack of severe joint pain,” says Professor Till Uhlig. He has been leading the NOR-gout study, a collaborative project between the University of Oslo and Diakonhjemmet Hospital. To prevent new attacks, it is important to maintain low levels of uric acid in the body. However, pain relieving treatment alone does not result in a satisfactory low level of uric acid for patients. “It is of vital importance that we lower the uric acid levels in order to prevent new attacks, so the patient can be well in the long term. Lower uric acid levels will also lessen the impact of the disease on other organs, such as the heart and kidneys,” says Uhlig. Diets rich in fat and alcohol can trigger gout Who is at risk of getting gout? Most often, the reason why some people get gout is due to underexcretion of uric acid through the kidneys. This is a congenital disease for most people. For others, attacks can be triggered by large, lavish meals, usually with a high intake of food rich in fat and purines, and large quantities of alcohol. Alcohol also contributes to the breaking down of purine into uric acid. Being overweight can also be a factor in triggering episodes. Around 1–2 percent of the Norwegian population suffers from gout. A treatment which lowers the uric acid levels The inflammation is caused by crystallization of uric acid which is excreted into the joints, tendons or elsewhere in the body, which become red, swollen and painful. The NOR-Gout study has investigated targeted forms for treatment which are to lower the uric acid levels in the body, in order to protect patients from new attacks. “The study shows that lowering of the body’s uric acid levels is an effective treatment. This insight is important in order to be able to provide the patients with the best possible treatment,” says Uhlig. Gout can impair cardiovascular health It is very common that the joint in the big toe is attacked first. This is probably the most well-known symptom of gout. However, the disease can also cause several complications and sustained malfunctions of several joints simultaneously. “To successfully lower the uric acid levels in the blood over time, in order to avoid attacks in our patients, is particularly important as new studies suggest that cardiovascular health is also impaired in cases of poorly managed gout,” says Uhlig. Monthly check-ups and drug treatment In the NOR-gout study, the researchers treated more than 200 patients suffering from gout. All the patients had recently suffered attacks where they had excessive levels of uric acid in their blood. The objective of the treatment was to lower their uric acid levels, so that the risk of new attacks practically disappeared. “The patients were scheduled for monthly check-ups with doctors and nurses, where they were also given lifestyle advice. If needed, we also stepped up drug treatment to lower the uric acid levels further,” says the professor. Protects against new attacks This is the first time patients with regular gout have been treated with this combination of monthly check-ups and potential increases in drug treatment. This regime not only had a positive effect on the patients’ symptoms. It also showed that it is possible to reverse the process where uric acid is accumulated in bodily tissue. After one year, the accumulated uric acid in the patients’ joints had been significantly reduced. Source: Read Full Article
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गलत खानपानको समस्याका कारण युरिक एसिडको समस्याबाट धेरै जना पीडित हुने गर्छन् । शरीरमा युरिक एसिड बढ्दै गयो भने थुप्रै किसिमका स्वास्थ्य समस्या यसैको साइडइफेक्टको रुपमा उत्पन्न हुने गर्छ । जसमा घुँडामा हुने समस्या, जोर्नीको दुखाइ आदि समस्या समाधानको लागि असल खानपान शैली अंगीकार गर्नुपर्ने हुन्छ । शरीरमा युरिक एसिड बढेको समस्या विभिन्न अध्ययनका अनुसार ३० वर्षसम्म उमेर समूहका एक जना व्यक्तिलाई एक दिनमा करिब २४०० क्यालोरी खाना चाहिन्छ । ५० वर्षसम्मका मानिसको लागि २४०० क्यालोरी खाना चाहिन्छ । ५० वर्षभन्दा माथिल्लो उमेरका मान्छेलाई दैनिक १८०० देखि १६०० क्यालोरी खाना आवश्यक पर्छ । यदि हामी अधिक मात्रामा क्यालोरी लिने र पर्याप्त एक्सरसाइज गर्ने हो भने शरीरमा युरिक एसिडको मात्रा बढ्न जान्छ । शरीरमा अधिक आइरन, प्रोटिन र अल्कोहलिक वस्तुहरूले शरीरमा एसिडको मात्रा बढाउने गर्छन् । जब शरीरमा एसिड बढ्दो मात्रामा हुन्छ, तब किड्नीको फङ्सनमा समस्या हुन थाल्छ । एक सामान्य व्यक्तिको १ ग्राम रगतमा ०.०७ मिलियुरिक एसिड हुने गर्छ । बिनाकारण बढ्न सक्छ युरिक एसिड युुरिक एसिड बढ्ने प्रमुख कारण भनेको शरीरमा एसिडको मात्रा बढाउने तत्वहरुको प्रभाव हो । किड्नी खराब हुने कारणले शरीरमा फिल्टरेसनको प्रक्रिया कम हुने गर्छ । त्यसपछि शरीरमा रहेको युरिया युरिक एसिडमा बदलिने गर्छ । यो युरिक एसिड हड्डीहरुको बीचमा प्रवेश गर्छ जसले दुखाइ बढाउने गर्छ । युरिक एसिड बढ्नुको प्रमुख लक्षण धेरैभन्दा धेरै अवस्थामा युरिक एसिडको दुखाइ एसिडहरुकै कारण हुने गरेको छ । उच्च युरिक एसिडको समस्याबाट पाचनतन्त्र कमजोर हुने गर्छ । यसका अतिरिक्त जोर्नीहरूमा निरन्तर दुखाइ हुनु, खासगरी घुँडामा हुने समस्या यसको मुख्य लक्षण हो । यसबाट बच्न कस्तो व्यवहार अपनाउने ? हाइ युरिक एसिड (हाइपरसेमिया) लाई कम गर्न आइरन र प्रोटिनको मात्रा सीमित गर्नुपर्छ । यदि यो अधिक मात्रामा रह्यो युरिक एसिडको समस्या बढ्दै जान्छ । यसका साथै युरिक एसिडको समस्या भएका व्यक्तिहरूले दूध, दही जस्ता दुग्ध पदार्थको सेवन कम गर्नुपर्छ । यी आयुर्वेदिक उपायहरू युरिक एसिड नियन्त्रणमा प्रभावकारी हुन्छ सामान्यतया युरिक एसिडलाई नियन्त्रण गर्नको लागि पहिले घरेलु औषधिको प्रयोग गर्न सकिन्छ । यस्तो केही घरेलु उपायहरु हुन्छन् जसले युरिक एसिडको लेबल कन्ट्रोल गर्न सकिन्छ । –कागतीको सेवा युरिक एसिड नियन्त्रण गर्नको लागि अचुक औषधि हो । –बेकिङ सोडामा पनि युरिक एसिड नियन्त्रण गर्ने क्षमता रहन्छ –एप्पल साइडको बिनेगरमा पनि युरिक एसिड विरुद्ध लड्ने क्षमता पाइन्छ । अनलाइनखबर बाट सभार