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Положителният ефект от витамин K и възможността да се поддържат силни кости и здрава сърдечно-съдова система все повече се признава. За жалост човешкото тяло не може да синтезира витамин К само. То трябва да се набавя с храната. Витамин K е необходим за производството на протромбин в черния дроб, който играе най-важната роля за кръвосъсирването. Освен това други кръвосъсирващи фактори, произвеждани в черния дроб, изискват наличието на витамин К. С недостига на протромбин или някой от тези фактори кръвта се съсирва бавно или изобщо не се съсирва и дори леко нараняване може да причини продължително кървене. Витамин К влияе и на поемането на калция в костите. Продължителният недостиг на витамин К може да доведе до остеопороза – костите стават крехки и чупливи. За радост, тези дефицити са рядкост и здравите хора не се нуждаят от допълнителни добавки. Недостигът на витамин К настъпва при тежки чревни и чернодробни заболявания и продължително лечение с антибиотици. Лекарствата за намаляване на холестерола възпират абсорбирането на витамин К в кръвта. При пациенти, които взимат антикоагуланти, действието на витамин К е блокирано и това може да доведе до остеопороза. Човекът не е способен да синтезира витамин К. Затова е необходимо той да се набавя с храната. Витамин К се съдържа основно в зеленолистните зеленчуци (напр. броколи, маруля, зеле, спанак), в ягодите, соевото масло и в някои продукти от животински произход (напр. яйца, говежди черен дроб). Имайте здрави кости с витамин K Научете повече за здравето си на Как да се справим с недостига на витамини през пролетта?витамин K, източници на витамин К, остеопороза, поемане на калция, протромбин, съсирване на кръвта
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Information Page General Information Also called the anti-hemorrrhagic factor, vitamin K was first discovered by a Danish scientist who demonstrated its role in blood coagulation. The Danish spelling is “koagulation”, hence the letter K designation. Substances with vitamin K activity are quinones. K1 or phylloquinone is present in green leaves; K2 or famoquinone was isolated from putrefied fishmeal. K3 or menadione is a synthetic form. There are some synthetic water-soluble vitamins (e.g. Synkayvite and Hykinone) for vitamin K administration and for clinical use when fat absorption is impaired. The reference standard is menadione. One unit vitamin K = 1 microgram menadione. Food Sources Vitamin K is readily available in both plant and animal based food. Animal Sources Includes organ meat such as liver and egg yolk contain or are rich sources of vitamin K. Plant Sources Dark green leaves, wheat bran, vegetable oils, especially soybean oil and wheat germ oil are excellent food sources. Good amounts are present in tomatoes, tubers, seeds and legumes. Benefits and Therapeutic Effects The most important biological role of vitamin K is the maintenance of prothrombin level in blood plasma. The coagulation of blood is a series of reactions that depend on several factors. Prothrombin and Proconvertin are among these and vitamin K is needed in the synthesis of both. Students, especially nutrition majors, are encouraged to probe further on blood coagulation by referring to a recent biochemistry or physiology textbook. Vitamin K is also needed in phosphorylation, a chemical process that adds the phosphate radical to glucose so that its passage through cell membranes is hastened. In lower animals, Vitamin K is essential for cellular respiration, and in plants, photosynthesis requires vitamin K. The less known function of vitamin K which was recently observed is to help synthesize osteocalcin, a protein found in the bones. The function of osteocalcin, which is the second most abundant type of protein in the bones, is to bind calcium. Signs of Deficiency Deficiency in vitamin K results in hemorrhagic disease in the newborn and delayed blood clotting time in adults. Dietary deficiency of vitamin K rarely occurs; inadequacy may be conditioned or induced by intestinal and liver disorders, obstruction of the bile duct and the use of antivitamins. Dosages Exact amounts of vitamin K requirement are not known due to intestinal synthesis and variable content in food sources. It is assumed that an average mixed diet has normal vitamin K intakes for most individuals. However, a normal dose of 1 to 2 milligrams is adequate for prophylaxis. Side Effects and/or Toxicity Excessive vitamin K is not observed to an extent as hypervitaminosis A or D, unless massive doses of the synthetic form have been administered. The toxic effects of vitamin K are: vomiting, hemolysis and albuminuria. Kenicterus is a condition resulting from the accumulation of bile pigments in the gray matter of the central nervous system. This has been observed in infants with uncontrolled synthetic vitamin K therapy. Conclusion Vitamin K is an essential nutrient in our body and although its toxicity in excess amounts have not been demonstrated in man compliance of its dosages is recommended for safety purposes. Life Extension Super K with Advanced K2 Complex Softgels, 90-Count