http___fitness1.bg_nb-glucosamine-sulfate__1.xml
http___www.arthritis-treatment-and-relief.com_glucosamine-arthritis.html.xml
1.1 2.1 3.1 4.1 5.1 5.2 5.3 5.4 5.5 5.6 6.1 7.1 7.2 7.3 7.4 8.1 8.2 9.1 10.1 10.2 10.3 10.4 11.1 11.2 12.1 13.1 14.1 15.1 15.2 15.3 16.1 16.2 16.3 17.1 17.2 17.3 18.1 19.1 20.1 20.2 21.1 22.1 22.2 23.1 23.2 23.3 23.4 24.1 24.2 24.3 25.1 26.1 26.2 26.3 26.4 27.1 27.2 27.3 28.1 29.1
Категория: За стави и сухожилия Марка: Nature's Bounty Разфасовка: 60 капсули Глюкозаминът е естествен химически елемент, намиращ се в човешкото тяло. Той се намира в течността, която е около ставите. Глюкозаминът също така се съдържа и на други места в природата. Например, глюкозамин сулфат, който се използва в хранителни добавки, често се събира в черупките от миди. Глюкозамин сулфата, използван в хранителните добавки, не винаги идва от природни източници. Той може да бъде направен в лаборатория. Глюкозамин сулфат се използва широко при артрит. Учените са го разучавали екстензивно за тази употреба. Най-често се използва за типа артрит, наречен остеоартрит. Това е най-често срещаната разновидност на артрит. През годините, хората са използвали глюкозамина за различни цели. Например, той е използван за глаукома и за загуба на тегло. Глюкозаминът се среща естествено в организма. Той помага на хрущяла да стане по-силен и по-твърд. Глюкозаминовите добавки обикновено са направени от протеин, открит в черупките на скариди, раци и други. Някои изследвания показват, че глюкозаминовите добавки облекчават болката при някои хора с остеоартрит (OA) на коляното. Артрозата, наричана още дегенеративни ставни заболявания, е най-често срещаният тип на артрит. Тя е свързана с разпределението на хрущяла в ставите и често се среща в бедрата, колената и гръбнака, отразява се и на ставите на големия пръст. Има различни форми на глюкозамин включително и глюкозамин сулфат глюкозамин хидрохлорид N-ацетил-глюкозамин. Тези различни химикали имат някои прилики, но те не могат да имат същия ефект, когато се приемат като хранителна добавка. Повечето от научните изследвания за глюкозамин са направени на глюкозамин сулфат. Информацията на тази страница се отнася до глюкозамин сулфат. Хранителните добавки, които съдържат глюкозамин често съдържат допълнителни съставки. Тези допълнителни съставки са най-често хондроитин сулфат, МСМ, или хрущял от акула. Някои хора мислят, че тези комбинации работят по-добре, отколкото глюкозамин сулфат сам. Глюкозамин сулфат и хондроитин сулфат са компоненти на нормалния хрущял. Те са градивните блокове за proteoglycans и стимулират хондроцитите да направят нов колаген и proteoglycans. Тъй като с тези добавки стимулират създаването на нови компоненти на хрущяла, приложенията могат да бъдат в състояние да помогнат на тялото да ремонтира повреденият хрущял. Съществуват доказателства, от пациенти, че глюкозаминът може да намали болката от остеоартрозата, обикновено в рамките на няколко седмици до няколко месеца след започване на лечението. Глюкозаминът се съдържа също така в някои кожни кремове използвани за контрол на болката артрит. Тези кремове обикновено съдържат камфор и други съставки, в допълнение към глюкозамин. Как действа той? Глюкозамин сулфат е химически елемент, намерен в човешкото тяло. Той се използва от организма да произвежда различни химикали, които са свързани с изграждането на сухожилия, хрущяли и течността, която заобикаля ставите. Ставите са омекотени от течността и хрущяла, които ги обкръжават. При някои хора с остеоартрит, хрущяла се разгражда. Това води до повече съвместно триене, болка и скованост. Изследователите смятат, че приемането на допълнителен глюкозамин може да допринесе за увеличаване на хрущяла и течността около ставите или предотвратяване на разбиването на тези вещества. Някои изследователи смятат "сулфатната" част на глюкозамин сулфат също за важна. Сулфатът е необходим на организма да произвежда хрущял. Това е една от причините, защо учените смятат, че глюкозамин сулфат може да работи по-добре в сравнение с другите форми на глюкозамин. Глюкозамин сулфат е форма, която е изпитана в десетки клинични проучвания. Тя е много подобна на глюкозамин HCl (хидрохлорид) в ефективността, тъй като сулфат е просто молекула превозвач на действителния глюкозамин. Друга популярна форма на глюкозамин е известна като глюкозамин HCL, или хидрохлорид. Някои изследвания са показали HCL като по-ефективен, а някои са показали сулфата като по-ефективен, така че би било разумно да се пробват и двата или поотделно или просто да се намери продукт, който съдържа както HCL, така и сулфат. Всички форми на глюкозамин произхождат от миди, и е доказано, че са ефективни при облекчаване при дискомфортта, свързан с артрит. Сулфатът и глюкозаминът (HCL) също имат много малко странични ефекти в сравнение с НСПВС, които могат да причинят вътрешни кръвоизливи и чернодробна недостатъчност. Купи Цена: 20 лв. Посочените цени са крайни с включено ДДС.
1.1 2.1 3.1 3.2 4.1 5.1 6.1 6.2 6.3 6.4 7.1 7.2 7.3 7.4 8.1 8.2 8.3 8.4 8.5 8.6 8.7 9.1 9.2 10.1 11.1 11.2 12.1 13.1 13.2 14.1 14.2 14.3 14.4 15.1 16.1 16.2 16.3 16.4 16.5 16.6 17.1 17.2 17.3 17.4 17.5 17.6 17.7 17.8 18.1 18.2 18.3 19.1 19.2 19.3 20.1 20.2 20.3 21.1 22.1 22.2 22.3 23.1 23.2 23.3 24.1 24.2 24.3 24.4 25.1 25.2 25.3 26.1 27.1 28.1 29.1 29.2 31.1 31.2 31.3 32.1 32.2 32.3 33.1 33.2 34.1 35.1 35.2 36.1 36.2 37.1 37.2 38.1 38.2 39.1 40.1 40.2 41.1 42.1 43.1 44.1 45.1 46.1 47.1 47.2 48.1 48.2 48.3 49.1 49.2 49.3 50.1 51.1 52.1 53.1 54.1 55.1 56.1 57.1 58.1
Glucosamine arthritis by Nathan Wei, MD, FACP, FACR Nathan Wei is a nationally known board-certified rheumatologist and author of the Second Opinion Arthritis Treatment Kit. It's available exclusively at this website... not available in stores. Click here: Second Opinion Arthritis Treatment Kit Osteoarthritis (OA), the most widespread type of arthritis, is a degenerative disease of the joints. Although sometimes capable of causing acute inflammation, it is most commonly a "wear-and-tear" disease involving degeneration of joint cartilage and formation of bony spurs within various joints. Trauma to the joints, repetitive occupational usage, and obesity are risk factors. Most people over 60 years of age have this affliction to some extent, with approximately 16 million sufferers requiring medical care. The main goal of treatment is to relieve pain. In recent years, glucosamine and chondroitin have been widely promoted as a treatment for OA. Glucosamine, an amino sugar, is thought to promote the formation and repair of cartilage. Chondroitin, a carbohydrate, is a cartilage component that is thought to promote water retention and elasticity and to inhibit the enzymes that break down cartilage. Both compounds are manufactured by the body. Laboratory studies suggest that glucosamine may stimulate production of cartilage-building proteins. Other research suggests that chondroitin may inhibit production of cartilage-destroying enzymes and fight inflammation too. Glucosamine supplements are derived from shellfish shells; chondroitin supplements are generally made from cow cartilage. Human studies have shown that either one may relieve arthritis pain and stiffness with fewer side effects than conventional arthritis drugs. But two problems remain. First, there has not been enough high-quality or long-range research to determine whether their use is practical. Second, because dietary supplement manufacture is not regulated, product quality (especially of chondroitin products) is not assured. Some published studies comparing glucosamine or chondroitin to various standard medications have found that the drugs worked faster than the supplements. But they also found that several months after treatment ended, the analgesic effect of the supplements remained stronger. In March 2000, a study in the Journal of the American Medical Association concluded: Trials of glucosamine and chondroitin preparations for OA symptoms demonstrate moderate to large effects, but quality issues and likely publication bias suggest that these effects are exaggerated. Nevertheless, some degree of efficacy appears probable for these preparations [1]. An accompanying editorial cautioned: As with many nutraceuticals that currently are widely touted as beneficial for common but difficult-to-treat disorders, the promotional enthusiasm often far surpasses the scientific evidence supporting clinical use. Until high-quality studies, such as the National Institutes of Health study, are completed, work such as [the meta-analysis] is the best hope for providing physicians with information necessary to advise their patients about the risks and benefits of these therapies [2]. In 2001, the Lancet published the results of a three-year double-blind clinical trial involving 212 people with osteoarthritis who took either glucosamine or a placebo. The researchers found that symptoms improved 20% to 25% in the glucosamine group but worsened slightly in the placebo group. The x-ray examinations showed that serious narrowing of the knee-joint space -- a sign of progression of the disease -- occurred in only half as many patients taking glucosamine as in those receiving the placebo [3]. However, the Medical Letter has reported that the x-rays were questionably standardized; there was little correlation between the joint-space changes and the symptoms; and there was no difference between the glucosamine and placebo groups in the use of standard medication to "rescue" patients [4]. As for chondroitin, a recent analysis of the combined results of seven randomized, controlled trials indicated that the supplement may reduce osteoarthritis symptoms and improve function by an average of some 50%, although the studies had flaws that may exaggerate the benefits. In the United States, glucosamine and chondroitin products are marketed as "dietary supplements." Glucosamine is available in many forms, including glucosamine sulfate, glucosamine hydrochloride (HCl), and N-acetylglucosamine (NAG), and may also contain a potassium chloride or sodium chloride salt. However, there appears to be no conclusive evidence that one form is better than another [5]. Chondroitin is typically sold as chondroitin sulfate. In December 1999 and January 2000, ConsumerLab.com tested 25 brands of glucosamine, chondroitin and combination products and found that (a) all 10 glucosamine-only products, passed the test but 2 chondroitin-only and 6 out of 13 combination products did not (because their chondroitin levels were too low). In January 2001, one of the combination products was removed because its manganese level was judged to be too high. No study so far has found any serious side effects from either glucosamine or chondroitin. The most common side effects are increased intestinal gas and softened stools. However, animal research has raised the possibility that glucosamine may worsen insulin resistance, a major cause of diabetes. So far, studies in humans have not substantiated that risk. Nevertheless, people with diabetes should monitor their blood-sugar level particularly carefully when using that supplement. There have been no reports of allergic reactions to glucosamine. But since it's made from shellfish shells, people who are allergic to seafood should use it cautiously, watching for reactions, or avoid it entirely. As for chondroitin, it can cause bleeding in people who have a bleeding disorder or take a blood-thinning drug. Respected medical authorities regard use of these compounds as plausible and agree that more research is needed to place them in proper perspective. However, disagreement exists about how practical it is to use them now. Consumer Reports states: The long-term safety and efficacy of glucosamine and chondroitin remain unclear. Still, our medical consultants say there's enough evidence to conclude that products containing the amounts of glucosamine, chondroitin, or both that worked in the clinical trials might be worth trying for people with osteoarthritis -- particularly if they've experienced or are likely to experience significant side effects from conventional painkillers. (Those amounts were 1,500 milligrams per day of glucosamine salt -- glucosamine bound to another molecule -- and 1,200 milligrams of chondroitin salt.) It may take two months . to produce any significant improvement. If you see no effect by then, it's probably best to try a different approach [6] The Medical Letter, which is the medical profession's most respected drug advisory publication, is more conservative: Glucosamine with or without chondroitin may have some beneficial effect on osteoarthritis, and studies up to 3 years in duration have found no more adverse effects than with placebo, but most Medical Letter consultants are skeptical. Whether glucosamine offers any advantages over better established drugs such as acetaminophen, traditional NSAIDS or selective Cox-2 inhibitors remains to be determined. As with other dietary supplements, the quality and purity of the ingredients may vary [4]. A clinical trial that should add considerably to medical knowledge about glucosamine and chondroitin has been funded and is now recruiting patients. It will be a 24-week, placebo-controlled, double-blind, study that will evaluate the effect on osteoarthritic knee pain of glucosamine hydrochloride, chondroitin, a combination of the two, and celicoxib among 1588 participants at 13 centers throughout the country over a 27-month period [8]. The estimated completion date in March 2005. (The results of this trial-GAIT trial funded by the National Institutes of Health- were released in early 2006. While glucosamine/ chnodroitin do not appear to be effective for mild OA, they do seem to be effective for moderate to severe OA. In addtion, the x-ray data is still too early to interpret. Bottom Line: Keep taking your supplements.) Decisions to use glucosamine or chondroitin must be based on information that is far less complete than is desirable. In addition, product quality control is a significant problem. Here's some advice: • The first step in seeking care for arthritic symptoms should be to obtain a competent diagnosis. • The next step should be to explore the pros and cons of treatment options with a competent physician • If you decide to try glucosamine and/or chondroitin, have a knowledgeable physician guide how you do it. Ignore any practitioner or seller who promises a "miracle cure" for arthritis. Never buy a dietary supplement in response to a solicitation by mail or though s radio or television ad. McAlindon TE and others. Glucosamine and chondroitin for treatment of osteoarthritis: A systematic quality assessment and meta-analysis JAMA 283:1469-1475, 2000. [Full-text version is accessible online for JAMA subscribers.] Tanveer E, Anastassiades TP. Glucosamine and chondroitin for treating symptoms of osteoarthritis: Evidence is widely touted but incomplete. [Full-text version is accessible online for JAMA subscribers.] Reginster JY and others. Long-term effects of glucosamine sulfate on osteoarthritis progression: a randomized, placebo-controlled trial. Update on glucosamine for osteoarthritis. Product review: GLUCOSAMINE and CHONDROITIN. ConsumerLab Web site, accessed Jan 22, 2002. Joint remedies. Consumer Reports, Jan 2002. Vital Nutrients recalls Joint Ease & Verified Quality Brand Joint Comfort Complex because of adverse health risk associated with aristolochic acid. News release, May 24, 2001. Study of the efficacy of glucosamine and glucosamine/chondroitin sulfate in knee osteoarthritis. NIH Web site, accessed Jan 22, 2002. Other authorities claim the following... There have been many double blind placebo controlled trials and studies done on glucosamine. In many trials and studies, glucosamine has shown to be very effective at: • Easing osteoarthritis pain • Easing articular joint pain • Rehabilitating damaged cartilage • Slowing deterioration of cartilage from osteoarthritis • Improving mobility • Stimulating the production of proteoglycans, glycosaminoglycans, and synovial fluid With such great news spreading very quickly, the glucosamine industry became very large. Almost every major nutraceutical or vitamin company put out a glucosamine product, and today it can be bought in just about every food store, health food store, vitamin store, wellness clinic, and chiropractors office. However, in the rush to gain market share with their glucosamine product, companies often put out products with little regard to the quality of the product being produced. They rushed to the market and did not take the time to do essential testing procedures like perform lab analysis on their products. They used medium or low grade glucosamine products to save money and they produced glucosamine in pill or capsule form. All glucosamine products are not the same. There are six main factors some manufacturers claim that you need to analyze when selecting a glucosamine product. These are: • Amount of glucosamine per daily dose • Type of Glucosamine • Quality of Ingredients • Delivery System • Synergistic Ingredients • Price Per Day If you're not getting the results you should be, it's possible your glucosamine preparation is either not being absorbed properly or it is poor quality. As with any product, do your homework, ask your physician, and read the label! Return to arthritis home page.