http___en.fmpharm.co.rs__D0_BF_D1_80_D0_BE_D0_B8_D0_B7_D0_B2_D0_BE_D0_B4_neomethason_.xml
http___fmpharm.co.rs_proizvod_veterinarski-lekovi-neopen__1.xml
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Description Neomethason Composition: 1 ml solution for injection contains: Dexamethasone-sodium-phosphate 2.64 mg Indications: Treatment of diseases of the locomotor system of animals, as well as a variety of inflammation of joints (arthritis, periarthritis, poliarthritis), inflammation of the tendon sheath and tendon (tendinitis and tendovaginitis), inflammation (bursitis), inflammation of muscles (myositis), nerves (neuritis), painful injuries: sprains (dislocations), bruises (contusions), sprains (distortions), broken bones (fractures), allergic reaction, and ketosis, puerperal paresis, skin diseases and trauma during delivery. Dexamethasone is used as symptomatic therapy with antibiotics in the treatment of inflammation of the udder (mastitis) and MMA syndrome of sows, as well as in the treatment of inflammatory conditions of the respiratory system of horses, cattle, pigs, dogs and cats. Contraindications: application of the drug is contraindicated for animals hypersensitive to glucocorticoids or any component of the drug, in pregnancy (except in gravidity toxemia), recent surgical procedure (because it prevents the healing of wounds), with wounds that do not heal, glaucoma, edema, renal and heart failure, diabetes, steroid diabetes mellitus, hyperadenokorticism, blood dyscrasias, and ulceration of the gastric mucosa, acute tuberculosis, deep corneal ulcers, osteoporosis and demodicosis. The drug is not indicated for viral infections (during viremia), as well as laminitis in horses. It is not given for bacterial infections that were not treated with bactericidal antibiotics. Side effects: While a single dose of medication is generally well tolerated, its long-term use can cause serious side effects. Application of high doses of glucocorticoids in the period of a few weeks may cause suppression of the hypothalamic-pituitary- adrenocortical shaft. System use of corticosteroid, particularly at the beginning of therapy with this drug can cause polyuria, polidipsya and polifagya. Later there may appear a weakness of the muscles, osteoporosis and lethargy, as well as the appearance of hemorrhagic gastroenteritis, pancreatitis, dysfunction of liver and kidneys. There may occur glycosuria, leukopenia, trombocitopeny. Because of immunosuppressive effects of corticosteroids susceptibility of animals to bacterial and viral infections is increased. At long term usage its possible retention of sodium and water, with consequent edema. May cause anaphylactic reactions, in which case you should immediately apply adrenalin. Target species: horses, cattle, pigs, dogs and cats, Dosage and method of administration: The drug is given intramuscularly or locally in the burned tissue (intraarticular, perarticular, intrabursal) in a daily dose of: Horses, cattle: 2.5 mL/100kg body weight local 2-4ml Foals, calves: 0.5 mL/10kg body weight local 1-2ml Pigs: 0.5 mL/10kg body weight local 1-2ml Cats & Dogs: 0.25 mL/5kg body weight local 0.25-1ml The drug is administered once, but depending on the severity of the inflammatory process, in large animals dose can be repeated after 1 – 2 days, pigs and dogs after 1-2 days, and in cats after 2-3 days. Instructions for proper use of drugs: Therapy implement with the recommended therapeutic doses, because any increase in dose causes unwanted harder effects. Intraarticular use of this drug performed under strict aseptic conditions, and since exclude bacterial infection, fracture or aseptic necrosis of the bone. Be careful in the treatment of various inflammatory conditions because dexamethasone, as well as other glucocorticosteroids, may mask the clinical picture and thus facilitate the spread of microorganisms. The application of high doses of glucocorticoids in the period of a few weeks may cause suppression of the hypothalamic-pituitary-adrenocortical axis. Because of that it is recommended to gradually reduce the dose of glucocorticoids until the therapy ends. Withdrawal period: Meat of treated cattle and pigs is not for human consumption during treatment or for 21 days after the last application of medicine. Milk of cows is not for human consumption during treatment or 84 hours after the last application of medicine. Medicine is not given to horses whose meat is intended for human consumption. Special warnings For use on animals: When given to cows in lactation it reduces milk production during 3-5 days, with what animal owners must be familiar. All glucocorticoids, including dexamethasone can cause laminitis at susceptible horses. It is not given 24 hours before the race. Estrogens potentiate the effect of glicocortikoids when used simultaneously. NSAIL potentiate the side effects of glicocortikoids on digestive system. Glicocortikoids reduce the efficiency of bacteriostatic antibiotics. Corticosteroids are not applied at the time of vaccination and 3-4 weeks before and after vekcination, due to its immunosupressive effects. Antihistamines and barbiturates stimulate metabolism corticosteroids by induction of liver enzymes, and thus reduce the activity dexamethasone. On the other hand, the use of dexamethasone reduces the time of barbiturates. Use during pregnancy and lactation Do not recommend the use of corticosteroids during gravidity. The drug applied in early pregnancy can cause fetal malformations. In the last third of pregnancy can cause premature birth, fetal death, placental retention and metritis. At lactating cows can lead to a reduction in milk production. Special considerations for people who give animals medicine Avoid direct contact with the product. Wash hands after application. Do not eat or drink while handling with product. In case of contact with eyes, they should be immediately flushed with water. Special precautions for disposal and destruction of drug Unused drug or drug residues shall be destroyed in accordance with applicable regulations. Storage: Store in original container at temperatures up to 25 °C, out of reach of children. Shelf life: 2 years. Shelf life after first opening: 28 days at temperatures up to 25 ˚C Method of issuance: On prescription of veterinarian Packaging: Glass bottle of 20 mL and 50 mL. ATCvet code: QH02AB02 Number and date: Producer: “FM Pharm”, Subotica, 024/548-130
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Description Neopen Sastav: 1 mL suspenzije za injekciju sadrži Aktivna supstanca: Benzilpenicilin-prokain 300.000 i.j. Pomoćne supstance: Metilparahidroksibenzoat 1.0 mg Ostale pomoćne supstance: povidon K12; simetikon emulzija, dinatrijum-edetatt, kalijum dihidrogenfosfat i voda za injekcije. Indikacije: Lek je namenjen za terapiju primarnih i sekundarnih infekcija gastrointestinalnog, urogenitalnog i respiratornog trakta, kao i infekcija mekih tkiva i kože prouzrokovanih mikroorganizmima osetljivim na aktivnu supstancu preparata (kao što su aktinomikoza, difterija teladi, mastitis, metritis, pneumonija, infekcije rana, zarazna šepavost ovaca). Kontraindikacije: Lek se ne daje životinjama preosetljivim na peniciline i cefalosporine. Takođe, ovaj preparat se ne daje gravidnim krmačama i nazimicama, malim herbivorima i sportskim konjima 2 nedelje pre trke. Neželjena dejstva: Kod tretiranih životinja može doći do pojave reakcije preosetljivosti (alergija, anafilaksija), zatim nervnih poremećaja (ekscitacija, inkoordinacija, ataksija, povraćanje), eventualnog “vaginalnog pranja” i abortusa kod krmača i nazimica. Ukoliko primetite ozbiljno, ili bilo kakvo drugo neželjeno dejstvo koje nije ovde navedeno, o tome obavestite nadležnog veterinara. Ciljne vrste životinja: Konji, goveda, ovce, svinje, psi i mačke. Doziranje i način primene: Lek se aplikuje i.m. u dnevnoj dozi koja iznosi za: Konje i goveda: 2-3 ml / 60 kg t.m. (terapijska doza benzilpenicilin-prokaina od 10 do 15 mg/kg t.m.) Ovce: 0.5 ml / 10 kg t.m. Svinje: 1.0 ml / 10 kg t.m. Psi telesne mase od 50 kg dobijaju 5 do 6 ml leka U zavisnosti od težine infekcije terapija traje do izlečenja (obično 3-5 dana). Pre upotrebe bočicu dobro izmućkati. Uputstvo za pravilnu upotrebu leka: Ne davati lek i.v. i intratrahealno. Ako je doza leka kod goveda i konja veća od 20 mL, kod svinja od 10 mL, a kod ovaca i koza od 5 mL, lek se aplikuje na najmanje dva mesta. Moguća je alergijska reakcija kod ljudi koji dolaze u kontakt sa lekom. Pre upotrebe bočicu dobro promućkati. Karenca: Meso: goveda, ovce i svinje: 7 dana Mleko krava: 84 sata Lek se ne primenjuje kod ovaca u laktaciji niti kod konja čije se meso koristi za ishranu ljudi. Posebna upozorenja za čuvanje leka: Čuvati van domašaja dece. Čuvati u originalnom pakovanju, na temperaturi do 2-8˚C. Rok upotrebe: 1 godina. Rok upotrebe posle prvog otvaranja: 28 dana, na temperaturi do 2-8˚C. Posebna upozorenja Za primenu na životinjama: Antibiotici širokog spektra i eritromicin smanjuju antimikrobni efekat penicilina. Neomicin smanjuje resorpciju penicilina u digestivnom traktu a oksifenbutazon i probenecid smanjuju ekskreciju penicilina u bubrezima. Penicilin pojačava efekat antikoagulantnih sredstava. Metacilin, kloksacilin, cefalosporini, polimiksin B i aminoglikozidni antibiotici pojačavaju efekat penicilina. Lek se ne daje zajedno sa bakteriostatskim antimikrobnim lekovima. Upotreba tokom graviditeta i laktacije: Preparat se ne koristi kod gravidnih krmača i nazimica. Ne daje se ovcama u laktaciji čije se mleko koristi za ishranu ljudi. Predoziranje: Soli penicilina su veoma malo toksične. Životinje dobro podnose visoke doze benzilpenicilina. U slučaju ekstremno visokih doza može doći do senzibilizacije i pojave alergijskih reakcija. Inkompatibilnost: Penicilin u rastvorima precipitiraju ili inaktiviraju aminofilin, askorbinska kiselina, cefalotin, fenotijazin, natrijum hidrogenkarbonat i vitamini B kompleksa. Penicilin se postepeno inaktiviše u rastvorim aza infuziju. Kiseline, baze i oksidaciona sredstva brzo inaktiviraju penicilin. Posebna upozorenja za osobe koje daju veterinarski lek životinjama: Penicilin u 10% ljudi dovodi do hipersenzitivnih reakcija. Osobe preosetljive na penicilin ne treba da rukuju ovim lekom. Prilikom primene leka treba izbegavati direktan kontakt leka sa kožom i sluzokožom, odnosno očima. Ruke posle svake primene treba oprati i lek držati van domašaja dece. U slučaju pojave znakova preosetljivosti obrati se lekaru. Posebne predostrožnosti kod odlaganja i uništavanja leka: Neiskorišćen lek ili ostaci leka se uništavaju u skladu sa važećim propisima. Pakovanje:Unutrašnje pakovanje je ujedno i spoljašnje: Boca od obojenog stakla (II hidrolitička grupa), zapremine 100 ml, zatvorena čepom od brombutila i aluminijumskim poklopcem. Način izdavanja: Lek se može izdavati samo na recept veterinara. ATCvet kod: QJ01CE09 Proizvođač: “FM Pharm” d.o.o., Subotica