http___en.fmpharm.co.rs__D0_BF_D1_80_D0_BE_D0_B8_D0_B7_D0_B2_D0_BE_D0_B4_neostrep_.xml
http___fmpharm.co.rs_proizvod_veterinarski-lekovi-neostrep__1.xml
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Description Neostrep Composition: 1 ml suspension for injection contains: Benzylpenicillin-procaine 200.000 iu Dihydrostreptomycin 200 mg Indications: The preparation is intended for the treatment of acute and chronic mixed, primary and secondary infections of the respiratory, urinary and gastrointestinal tract and soft tissue skin infections caused by microorganisms sensitive to the active substance in the preparation. Contraindications: The drug is not administered to animals hypersensitive to penicillins, cephalosporins, and aminoglycosides, as well as to animals with impaired kidney, liver and cohleovestibular apparatus. Not should be used in pregnant sows and gilts because it can cause vaginal washing and abortus. Not given to small herbivores (guinea pig, hamster, gerbil). The preparation is not given to quite young animals and racehorses 2 weeks before the race. The drug is not indicated for sheep and goats whose milk is used for human consumption. Do not give to horses whose meat is used for human consumption. Do not give medication intravenously. Side effects: At animals that received NEOSTREP they may develop hypersensitivity reactions (allergy, anaphylaxis), and nerve disorders (anxiety, uncoordinated movements, vomiting, cramps, hearing loss). At this medication are especially susceptible pigs where, after the application, can occur hyperpyrexia, vomiting, swelling of the vulva, cyanosis of the extremities. At pregnant sows and gilts there may occur vaginal washing and abortion. At the site of drug administration, local reaction is possible, that spontaneously passes. Target species: Horses,cattle,sheep,goats,pigs and dogs. Dosage and method of administration: The drug is applied intramuscularly once a day at the rate of 0.5 to 1 ml / 10 kg body weight for all target species. The application is repeated daily for 5 days. Instructions for proper use of drugs: Shake the bottle before use. Do not exceed the recommended dose. If the dose for cattle and horses greater than 10 ml, pigs, sheep, goats and 5 ml, and 2 ml for dogs medicine is applied on more injection sites. Do not use this medication simultaneously with bacteriostatic drugs (tetracyclines, sulfonamides, macrolides, lincosamids) due to the antagonistic action. It may be associated with allergic reactions. In this case apply antihistamines and glucocorticoids. Withdrawal period: The meat of treated animals is not for human consumption during treatment and 30 days after the last administration of the drug. Milk should not be used for human consumption during treatment and 4 days after the last application of the medicine. The meat of treated horses is not used for human consumption. The drug is not used in sheep and goats whose milk is used for human consumption. Special considerations: For use in animals: It is possible allergic reaction to drug. In this case antihistamines and glukokortikoides should be applied. On this medication are especially susceptible pigs at which may occur after the use of hyperpyrexia, vomiting, swelling of the vulva, cyanosis of the extremities and even abortus. Should not be used at the same time as bacteriostatic drugs (tetracyclines, sulfonamides, macrolides, lincosamides) due to the occurrence of antagonism. Penicillin enhances the effect of anticoagulation substances. Nafcilin, methicillin, koksicilin, cephalosporins, aminoglycosides and polymyxin B enhance antimicrobial activity penicilina. Drug does not apply to any myorelaxants, magnesium salts and general anesthetics because potentiation of neuromuscular paralysis, which usually causes dihidrostreptomicin. Also, do not apply at the same time or with a diuretic furosemide and other potentially nephrotoxic and ototoxic drugs. Acides and bases inactivate dihydrostreptomycin . In the absence of incompatibility studies, the drug must not be mixed with other veterinary medicinal products. Use in pregnancy and lactation: The drug can be used in pregnancy and during lactation, but with caution because of possible hearing damage of fetus. At pregnant sows and gilts it can cause vaginal washing and abortion. Special considerations for persons administering the veterinary medicinal product to animals: After injection, inhalation, ingestion or topical application at allergic people penicillins may cause reactions of hypersensitivity. Persons hypersensitive to penicillins may also be oversensitive on cefalosporine. Alergic reactions to these antibiotics are sometimes very severe so in such circumstances you should seek medical help. Persons with known hypersensitivity to penicillins and cephalosporins should not shake hands with them because caused anaphylactic reactions can be hazardous to life. After application of the drug hands should be washed with soap and water, and better protection is achieved by wearing protective gloves. Special precautions for disposal and destruction of drug Unused drug or drug residues shall be destroyed in accordance with applicable regulations. Storage: Store in original container at temperatures up to 25 ° C, out of reach of children. Shelf life in original packaging: 2 years. Shelf life after first opening: 28 days at temperatures up to 25 ˚ C Method of issue: on prescription of veterinarian. Packaging: bottle of dark glass type II of 100 mL, closed with bromobutyl rubber stopper and aluminum cap . ATCvet code: QJ01RA01 Number and date of registration: Producer: “FM Pharm”, Subotica, 024/548-130
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Description Neostrep Sastav: 1 mL suspenzije za injekciju sadrži: Aktivne supstance: Benzilpenicilin-prokain 200.000.i.j. Dihidrostreptomicin-sulfat 200 mg Pomoćne supstance: Metilparahidroksibenzoat 1.0 mg Ostale pomoćne supstance: Natrijum formaldehidsulfoksilat, Natrijum citrat, Kalijum dihidrogenfosfat, Dinatrijum EDTA , simetikon emulzija, povidon K12 i voda za injekcije Indikacije: Lek je namenjen za terapiju mešanih akutnih i hroničnih, primarnih i sekundarnih infekcija respiratornog (Pasteurella spp, Hemophylus spp, Klebsiella spp, Mycobacterium tuberculosis), urogenitalnog i gastrointestinalnog trakta kao i infekcije mekih tkiva kože prouzrokovanih mikroorganizmima osetljivim na aktivne supstance u preparatu (Brucella spp, Salmonella spp, Shigella spp, Leptospira canicola, Corinebacterium spp, E. coli, Vibrio foetus, Clostridium tetani, Cl. perfringens, Cl. renale, Staphylococcus aureus, Streptococcus agalactie, Corinebacterium pyogenes, Erysipelothrix insidiosa, Bacillus anthracis i Actinomyces bovis). Kontraindikacije: Lek se ne aplikuje kod životinja preosetljivih na peniciline, cefalosporine i aminoglikozide, kao ni kod životinja sa oštećenjem bubrega, jetre i vestibulokohlearnog aparata. Ne treba ga koristiti kod gravidnih krmača i nazimica jer može uzrokovati pojavu vaginalnog pranja i abortus. Ne daje se malim herbivorima (zamorac, hrčak, gerbil). Preparat se ne daje sasvim mladim životinjama, kao i trkačkim konjima 2 nedelje pred trku. Lek se ne primenjuje kod ovaca i koza čije se mleko koristi za ishranu ljudi. Ne daje se konjima čije se meso koristi u ishrani ljudi. Ne davati lek intravenski. Neželjena dejstva: Kod životinja koje su primale ovaj lek može doći do pojave reakcije preosetljivosti (alergija, anafilaksija), zatim nervnih poremećaja (uznemirenost, nekoordinisano kretanje, povraćanje, grčevi, oštećenja sluha). Na ovaj lek su posebno osetljive svinje kod kojih se posle primene može javiti hiperpireksija, povraćanje, otok vulve, cijanoza ekstremiteta. Kod gravidnih krmača i nazimica moguća je pojava vaginalnog pranja i abortusa. Na mestu primene leka moguća je lokalna reakcija koja spontano prolazi. Ciljne vrste životinja: Konji, goveda, ovce, koze, svinje i psi. Doziranje i način primene: Lek se primenjuje intramuskularno, jednom dnevno u količini od 0.5 do 1 mL/10kg telesne mase za sve ciljne vrsta životinja. Aplikacija se ponavlja svakodnevno u toku 5 dana. Uputstvo za pravilnu upotrebu leka: Pre upotrebe promućkati bočicu. Ne prekoračivati preporučenu dozu leka. Ako je doza kod goveda i konja veća od 10 mL, kod svinja, ovaca i koza 5 mL, a kod pasa 2 mL lek se aplikuje na više injekcionih mesta. Ne upotrebljavati ovaj lek istovremeno sa bakteriostatskim lekovima (tetraciklini, sulfonamidi, makrolidi, linkozamidi) zbog antagonističkog delovanja. Moguća je pojava alergijskih reakcija. U tom slučaju treba primeniti antihistaminike i glukokortikoide. Karenca: Meso 30 dana Mleko krava: 4 dana Lek se ne primenjuje kod ovaca, koza i kobila u laktaciji, ukoliko se njihovo mleko koristi u ishrani ljudi, niti kod konja čije se meso koristi za ishranu ljudi. Posebna upozorenja za čuvanje leka Čuvati van domašaja dece. Čuvati u originalnom pakovanju, na temperaturi do 2-8˚C Rok upotrebe: 1 godina. Rok upotrebe posle prvog otvaranja: 28 dana, na temperaturi do 2-8˚C Ne koristiti lek posle roka naznačenog na pakovanju. Za primenu na životinjama: Moguća je pojava alergijskih reakcija na lek. U tom slučaju treba primeniti antihistaminike i glukokortikoide. Na ovaj lek su posebno osetljive svinje kod kojih se posle primene može javiti hiperpireksija, povraćanje, otok vulve, cijanoza ekstremiteta pa i abortus. Ne treba upotrebljavati ovaj lek istovremeno sa bakteriostatskim lekovima (tetraciklini, sulfonamidi, makrolidi, linkozamidi) zbog antagonističkog delovanja. Penicilin pojačava efekat antikoagulacionih supstanci. Nafcilin, meticilin, koksicilin, cefalosporini, polimiksin B i aminoglikozidi pojačavaju antimikrobnu aktivnost penicilina. Lek se ne primenjuje ni sa miorelaksansima, solima magnezijuma i opštim anesteticima zbog potenciranja neuromišićne paralize, koju inače prouzrokuje dihidrostreptomicin. Takođe, ne primenjuje se istovremeno ni sa diuretikom furosemidom i drugim potencijalno nefrotoksičnim i ototoksičnim lekovima. Kiseline i baze inaktivišu dihidrostreptomicin. U nedostatku studija inkompatibilnosti, lek se ne sme mešati sa drugim veterinarskim lekovima. Upotreba tokom graviditeta i laktacije: Lek se može koristiti u laktaciji i u toku graviditeta ali sa posebnim oprezom zbog mogućeg oštećenja sluha fetusa. Kod gravidnih krmača i nazimica može uzrokovati pojavu vaginalnog pranja i abortus. Predoziranje Samo višestruko prekoračenje propisanih doza dovodi do simptoma predoziranja (otežano disanje, hipersalivacija, ekscitacije, grčevi i konvulzije). Primenu treba odmah prekinuti i pristupiti simptomatskom lečenj. Predoziranje preparata i primena u toku vremena dužeg od preporučenog može prouzrokovati neuromišićnu blokadu, reverzibilnu gluvoću, ataksiju, poremećaj ravnoteže i nekoordinisanost pokreta, nistagmus i oštećenje bubrega kod tretiranih životinja. Inkompatibilnost Unedostatku studija inkompatibilnosti, lek se ne sme mešati sa drugim veterinarskim lekovima. Posebna upozorenja za osobe koje daju veterinarski lek životinjama: Penicilini mogu nakon injekcije, inhalacije, ingestije ili lokalne primene kod alergičnih osoba prouzrokovati reakcije preosetljivosti. Osobe preosetljive na peniciline mogu istovremeno biti preosetljive i na cefalosporine. Alergijske reakcije na ove antibiotike ponekad su vrlo teške pa je u takvim okolnostima potrebno zatražiti lekarsku pomoć. Osobe sa poznatom preosetljivošću na peniciline i cefalosporine ne smeju da rukuju sa njima jer nastala anafilaktička reakcija može da bude opasna po život. Posle aplikacije leka potrebno je ruke temeljno oprati vodom i sapunom, a bolja zaštita se postiže nošenjem zaštitnih rukavica. Posebne predostrožnosti kod odlaganja i uništavanja leka: Neiskorišćen lek ili ostaci leka se uništavaju u skladu sa važećim propisima. Režim izdavanja: Lek se može izdavati samo na recept veterinara. Pakovanje: Unutrašnje (ujedno i spoljašnje) pakovanje: bočica od obojenog stakla (II hidrolitička grupa), zapremine 100 ml, zatvorena lepom od brombutila i aluminijumskim poklopcem. ATCvet kod: QJ01RA01 Proizvođač: “FM Pharm” d.o.o., Subotica