http___en.fmpharm.co.rs__D0_BF_D1_80_D0_BE_D0_B8_D0_B7_D0_B2_D0_BE_D0_B4_neopen_.xml
http___fmpharm.co.rs_proizvod_veterinarski-lekovi-neopen__1.xml
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Description Neopen Composition: 1 ml suspension for injection contains: Benzylpenicillin-procaine 300,000 i.u. Indications: The preparation is intended for the treatment of primary and secondary infections of the gastrointestinal, genitourinary and respiratory tract and soft tissue infections and skin caused by microorganisms sensitive to the active substance of the preparation (such as actinomycosis, diphtheria calves, mastitis, metritis, pneumonia, wound infections, footrot in sheep) Contraindications: The drug is not administered to animals hypersensitive to penicillin and cephalosporins. Also, this product is not given to pregnant sows and gilts, small herbivores and sport horses 2 weeks before the race. Side effects: At treated animals there may occur hypersensitivity reactions (allergy, anaphylaxis), and nerve disorders (excitation, inkoordinacija, ataxia, vomiting) and possible “vaginal wash” and abortions in sows and gilts. Target species: horses, cattle, sheep, pigs, dogs and cats Dosage and method of administration: The drug is administered i.m., in daily dose: Horses and cattle: 2-3mL/60kg tm (therapeutic dose of benzylpenicillin-procaine – 10-15mg/kg of body weight) Sheep: 0.5 mL/10kg of body weight Pigs: 1.0 mL/10kg of body weight Cats: 0.12 – 0.25 mL (1-2kg of body weight) 0.25 – 0.50 mL (2-5kg of body weight) Dogs: 0.12 – 0.25 mL (1-2kg of body weight) 0.25 – 0.50 mL (2-5kg of body weight) 0.50 – 0.75 mL (5-10kg of body weight) 0.75 – 1.00 mL (10-25kg of body weight) 1.00 – 2.00 mL (25 kg or more) Depending on the severity of the infection therapy lasts (usually 3-5 days) Instructions for proper use of medicine: Do not give medication i.v. and intratraheal. If the dose for cattle and horses greater than 20 mL, in 10 mL of pigs and the sheep and goats of 5 mL, the drug is administered at least two places. It is possible an allergic reaction at people who come into contact with drugs. Before use shake vial well. Withdrawal period: Meat of treated cattle, sheep and pigs is not for human consumption during treatment and 7 days after the last application of drugs. Milk of cows is not used for human consumption during treatment or 3.5 days (84 h) after the last application of drugs . Drug does not apply in lactating sheep or a horse whose meat is intended for human consumption. Special considerations: For use in animals: Broad-spectrum antibiotics and erythromycin reduced antimicrobial effect of penicillin. Neomicin reduces absorption penicillin in the digestive tract and oksifenbutazon and probenecid reduce the excretion of penicillin in kidneys. Penicillin increases the effect of anticoagulants. Metacilin, cloxacillin, cephalosporins, polymyxin B and aminoglycoside antibiotics enhance the effect of penicilin. Drug is not given along with bacteriostatic antimicrobial drugs. Use in pregnancy and lactation: The product is not used in pregnant sows and gilts. Not given in lactating sheep whose milk is used for human consumption. Special considerations for persons administering the veterinary medicinal product to animals: Penicillin in 10% resulting in people hypersensitive reaction. People hypersensitive to penicillin should not handle this drug. When applying the drug should avoid direct contact with the drug skin and mucous membranes, or eyes. Hands after each application should be washed and medicine kept out of the reach of children. If the signs of hypersensitivity consult a physician. Special precautions for disposal and destruction of drug Unused drug or drug residues shall be destroyed in accordance with applicable regulations. Special considerations for storing drugs: Store in original container at temperatures up to 25˚C, Keep out of the reach of children. Shelf life: 2 years. Shelf life after first opening: 28 days, at a temperature up to 25 ˚ C Method of issue: on prescription of veterinarian. Packaging: bottle of dark glass type II of 100 mL, closed with bromobutyl rubber stopper and aluminum cap ATCvet code: QJ01CE09 Number and date of registration: Producer: “FM Pharm”, Subotica, 024/548-130
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Description Neopen Sastav: 1 mL suspenzije za injekciju sadrži Aktivna supstanca: Benzilpenicilin-prokain 300.000 i.j. Pomoćne supstance: Metilparahidroksibenzoat 1.0 mg Ostale pomoćne supstance: povidon K12; simetikon emulzija, dinatrijum-edetatt, kalijum dihidrogenfosfat i voda za injekcije. Indikacije: Lek je namenjen za terapiju primarnih i sekundarnih infekcija gastrointestinalnog, urogenitalnog i respiratornog trakta, kao i infekcija mekih tkiva i kože prouzrokovanih mikroorganizmima osetljivim na aktivnu supstancu preparata (kao što su aktinomikoza, difterija teladi, mastitis, metritis, pneumonija, infekcije rana, zarazna šepavost ovaca). Kontraindikacije: Lek se ne daje životinjama preosetljivim na peniciline i cefalosporine. Takođe, ovaj preparat se ne daje gravidnim krmačama i nazimicama, malim herbivorima i sportskim konjima 2 nedelje pre trke. Neželjena dejstva: Kod tretiranih životinja može doći do pojave reakcije preosetljivosti (alergija, anafilaksija), zatim nervnih poremećaja (ekscitacija, inkoordinacija, ataksija, povraćanje), eventualnog “vaginalnog pranja” i abortusa kod krmača i nazimica. Ukoliko primetite ozbiljno, ili bilo kakvo drugo neželjeno dejstvo koje nije ovde navedeno, o tome obavestite nadležnog veterinara. Ciljne vrste životinja: Konji, goveda, ovce, svinje, psi i mačke. Doziranje i način primene: Lek se aplikuje i.m. u dnevnoj dozi koja iznosi za: Konje i goveda: 2-3 ml / 60 kg t.m. (terapijska doza benzilpenicilin-prokaina od 10 do 15 mg/kg t.m.) Ovce: 0.5 ml / 10 kg t.m. Svinje: 1.0 ml / 10 kg t.m. Psi telesne mase od 50 kg dobijaju 5 do 6 ml leka U zavisnosti od težine infekcije terapija traje do izlečenja (obično 3-5 dana). Pre upotrebe bočicu dobro izmućkati. Uputstvo za pravilnu upotrebu leka: Ne davati lek i.v. i intratrahealno. Ako je doza leka kod goveda i konja veća od 20 mL, kod svinja od 10 mL, a kod ovaca i koza od 5 mL, lek se aplikuje na najmanje dva mesta. Moguća je alergijska reakcija kod ljudi koji dolaze u kontakt sa lekom. Pre upotrebe bočicu dobro promućkati. Karenca: Meso: goveda, ovce i svinje: 7 dana Mleko krava: 84 sata Lek se ne primenjuje kod ovaca u laktaciji niti kod konja čije se meso koristi za ishranu ljudi. Posebna upozorenja za čuvanje leka: Čuvati van domašaja dece. Čuvati u originalnom pakovanju, na temperaturi do 2-8˚C. Rok upotrebe: 1 godina. Rok upotrebe posle prvog otvaranja: 28 dana, na temperaturi do 2-8˚C. Posebna upozorenja Za primenu na životinjama: Antibiotici širokog spektra i eritromicin smanjuju antimikrobni efekat penicilina. Neomicin smanjuje resorpciju penicilina u digestivnom traktu a oksifenbutazon i probenecid smanjuju ekskreciju penicilina u bubrezima. Penicilin pojačava efekat antikoagulantnih sredstava. Metacilin, kloksacilin, cefalosporini, polimiksin B i aminoglikozidni antibiotici pojačavaju efekat penicilina. Lek se ne daje zajedno sa bakteriostatskim antimikrobnim lekovima. Upotreba tokom graviditeta i laktacije: Preparat se ne koristi kod gravidnih krmača i nazimica. Ne daje se ovcama u laktaciji čije se mleko koristi za ishranu ljudi. Predoziranje: Soli penicilina su veoma malo toksične. Životinje dobro podnose visoke doze benzilpenicilina. U slučaju ekstremno visokih doza može doći do senzibilizacije i pojave alergijskih reakcija. Inkompatibilnost: Penicilin u rastvorima precipitiraju ili inaktiviraju aminofilin, askorbinska kiselina, cefalotin, fenotijazin, natrijum hidrogenkarbonat i vitamini B kompleksa. Penicilin se postepeno inaktiviše u rastvorim aza infuziju. Kiseline, baze i oksidaciona sredstva brzo inaktiviraju penicilin. Posebna upozorenja za osobe koje daju veterinarski lek životinjama: Penicilin u 10% ljudi dovodi do hipersenzitivnih reakcija. Osobe preosetljive na penicilin ne treba da rukuju ovim lekom. Prilikom primene leka treba izbegavati direktan kontakt leka sa kožom i sluzokožom, odnosno očima. Ruke posle svake primene treba oprati i lek držati van domašaja dece. U slučaju pojave znakova preosetljivosti obrati se lekaru. Posebne predostrožnosti kod odlaganja i uništavanja leka: Neiskorišćen lek ili ostaci leka se uništavaju u skladu sa važećim propisima. Pakovanje:Unutrašnje pakovanje je ujedno i spoljašnje: Boca od obojenog stakla (II hidrolitička grupa), zapremine 100 ml, zatvorena čepom od brombutila i aluminijumskim poklopcem. Način izdavanja: Lek se može izdavati samo na recept veterinara. ATCvet kod: QJ01CE09 Proizvođač: “FM Pharm” d.o.o., Subotica