https___en.fmpharm.co.rs__D0_BF_D1_80_D0_BE_D0_B8_D0_B7_D0_B2_D0_BE_D0_B4_neocyclin-l-a_.xml
http___fmpharm.co.rs_proizvod_veterinarski-lekovi-neocyclin-l-a__1.xml
1.1 2.1 3.1 4.1 5.1 6.1 7.1 8.1 9.1 10.1 11.1 11.2 12.1 12.2 13.1 14.1 15.1 16.1 16.2 17.1 17.2 18.1 18.2 19.1 20.1 20.2 21.1 21.2 22.1 23.1 24.1 25.1 26.1 26.2 27.1 28.1 29.1 30.1 31.1 32.1 33.1 34.1 35.1 35.2 36.1 37.1 38.1 39.1 40.1 41.1 42.1 43.1 44.1 45.1 46.1 47.1 48.1 48.2 49.1 49.2 50.1 51.1 52.1 53.1 53.2 54.1 55.1 55.2 56.1 57.1 58.1 59.1 60.1 61.1 62.1 63.1 64.1 65.1 66.1 67.1 68.1 70.1
Description Neocyclin L.A. Composition: 1 ml solution for injection contains: Oxytetracycline (as dihydrate) 200mg Indications: Treatment of infections caused by organisms susceptible to oxytetracycline: Cattle: pneumonia, pasteurellosis, diphtheria calves, treatment of postoperative and postpartum infection. Sheep: pneumonia, mastitis, metritis, navel infection, postpartum infection, hoof rot. Pigs: pneumonia, enteritis, leptospirosis, mastitis, wound infections. Contraindications: Do not give to animals with known hypersensitivity to tetracycline. Do not give to animals with impaired liver and kidney. It is not given in the last third of pregnancy, as well as very young animals at the age of three weaks. Drug does not apply to horses, dogs and cats. Side effects: When applying therapeutic doses there may occur gastrointestinal disturbances (diarrhea), as a consequence of superinfection insensitive bacteria and fungi. Allergic reactions in hypersensitive animals are very rare, and in case of need apply antihistamines and corticosteroids. Sometimes at the area of application of the drug may occur local reaction that spontaneously disappear. Tetracyclines have anti anabolic effect and can cause azotemia that can worsen with extra application of glucocorticoids. This drug can also cause metabolic acidosis and electrolyte disbalance. At young animals it is possible to deposit in bone and staining teeth. It is possible the occurrence of fotodermatitis. Target species: Cattle, sheep and pigs. Dosage and method of administration: The drug is administered to cattle, sheep and pigs, deep intramuscularly at a dose of 20 mg oxytetracycline / kg of body weight, or 1 mL drug to 10 kg body weight, once. If necessary, the application can be repeated after 3 days. Instructions for proper use of drugs: If the dose exceeds 20 mL for adult cattle and pigs, 5 mL of sheep and 2 ml of lambs and piglets, the drug must be applied at in several places. Before drug administration, it is recommended to make antibiograms for isolated microorganisms, because of the increasing development of resistance to tetracycline. The most common drug-resistant bacteria of the genera Proteus, Pseudomonas and some strains of E. coli, Salmonella spp., Enterococcus spp., Shigella spp., Enterobacter spp. and some strains of Mannheimia (Pasteurella) haemolytica. Withdrawal period: Meat of treated animals is not for human consumption: – Cattle-31 days – Pigs – 18 days – Sheep – 9 days The drug is not indicated for animals whose milk is used for human consumption. Special considerations: For use in animals: Because of the known antagonism, do not apply the drug simultaneously with bactericidal antibiotics, such as B-lactam antibiotics, aminoglycosides, sulfonamides combination with trimethoprim, polymyxin. Use in pregnancy and lactation: It is not given in early pregnancy, during 2-3 weeks of gestation, as well as the last third of gravidity. Use of tetracycline during tooth and bone development can lead to tooth discoloration and developmental bone disorders. Like other tetracycline, oxytetracycline is excreted in milk of treated lactating animals. Special considerations for persons administering the veterinary medicinal product to animals: People with known hypersensitivity to tetracycline should not handle this drug. Due to possible irritation should avoid direct contact with the drug skin and mucous membranes. In case of contact with skin or eyes, wash immediately with water. Wash hands after applying the medicine. Special precautions for disposal and destruction of drug Unused drug or drug residues shall be destroyed in accordance with applicable regulations. Special considerations for storing drugs: Store in original container at temperatures up to 25°C, keep out of reach of children. Shelf life in original packaging: 2 years. Shelf life after first opening: 28 days at temperatures up to 25˚C Method of issue: on prescription of veterinarian. Packaging: bottle of dark glass type II of 100 mL, closed with bromobutyl rubber stopper and aluminum cap ATCvet code: QJ01AA06 Number and date of registration: Producer: “FM Pharm”, Subotica, 024/548-130
1.1 2.1 3.1 4.1 5.1 6.1 7.1 8.1 9.1 10.1 11.1 12.1 13.1 14.1 15.1 15.2 15.3 15.4 16.1 16.2 16.3 16.4 16.5 17.1 17.2 18.1 19.1 19.2 19.3 20.1 21.1 21.2 22.1 23.1 24.1 25.1 26.1 27.1 28.1 29.1 29.2 30.1 31.1 32.1 33.1 34.1 34.2 34.3 35.1 36.1 36.2 36.3 37.1 38.1 39.1 40.1 40.2 41.1 42.1 43.1 44.1 45.1 46.1 47.1
Description Neocyclin L.A. Sastav: 1 mL rastvora za injekciju sadrži Aktivna supstanca: Oksitetraciklin (u obliku dihidrata) 200 mg. Pomoćne supstance: Natrijum-formaldehidsulfoksilat 3.0 mg Ostale pomoćne supstance: magnezijum-oksid; monoetanolamin; dimetilacetamid; voda za injekcije Indikacije: Lečenje infekcija uzrokovanih mikroorganizmima osetljivim na oksitetraciklin: -Goveda: pneumonija (izazvana sa Pasteurella spp. i Hemophilus spp.), pastereloza, difterija teladi (Fusobacterium necrophorum), terapija postoperativnih i postpartalnih infekcija uzrokovanih sa stafilokokama i streptokokama osetljivim na oksitetraciklin. -Ovce: pneumonija (izazvana sa Pasteurella spp. i Hemophilus spp.), truljenje papaka (Fusobacterium necrophorum), mastitis, metritis, infekcija pupka, postpartalne infekcije izazvane mikroorganizmima osetljivim na oksitetraciklin. -Svinje: pneumonija (Pasteurella multocida), enteritis (E. coli), leptospiroza (Leptospira pomona), mastitis, infekcije rana izazvane mikroorganizmima osetljivim na oksitetraciklin. Kontraindikacije: Lek se ne daje životinjama sa poznatom preosetljivošću na tetracikline. Ne daje se životinjama sa poremećajima funkcije jetre i bubrega. Ne daje se u poslednjoj trećini graviditeta, kao i sasvim mladim životinjama u uzrastu do tri nedelje. Lek se ne primenjuje kod konja, pasa i mačaka. Neželjena dejstva: Pri primeni terapijskih doza mogu se javiti gastrointestinalne smetnje (dijareja), kao posledica superinfekcije neosetljivim bakterijama i gljivicama. Nekada se na mestu aplikacije leka može javiti lokalna reakcija koja spontano prolazi. Alergijske reakcije su veoma retke, a u slučaju pojave treba primeniti antihistaminike i kortikosteroide. Kod mladih životinja moguće je deponovanje u kostima i prebojavanje zuba. Moguća je pojava fotodermatitisa. Tetraciklini imaju anabolički efekat i mogu da prouzrokuju azotemiju koja se može pogoršati dodatnom primenom glukokortikoida. Ovaj lek takođe može prouzrokovati metaboličku acidozu i elektrolitni disbalans. Ciljne vrste životinja: Goveda, ovce i svinje. Doziranje i način primene: Lek se primenjuje kod goveda, ovaca i svinja, duboko intramuskularno, u dozi od 20mg oksitetraciklina /kg telesne mase, odnosno 1ml leka na 10kg telesne mase. Lek se aplikuje jednokratno. U slučaju potrebe, lek se može ponovo aplikovati posle 3 dana. Uputstvo za pravilnu upotrebu leka: U slučaju da doza prelazi 10ml za goveda i odrasle svinje, 5 ml za ovce i 2 ml za jagnjad i prasad, lek se mora aplikovati na više mesta. Pre primene leka preporučuje se izrada antibiograma za izolovane mikroorganizme, zbog sve većeg razvoja rezistencije na tetracikline. Najčešće su rezistentne bakterije iz rodova Proteus, Pseudomonas kao i neki sojevi E.coli, Salmonella spp., Enterococcus spp., Shigella spp., Enterobacter spp. i neki sojevi Mannheimia (Pasteurella) haemolytica. Karenca: Meso i jestiva tkiva: -goveda: 36 dana -svinje: 36 dana -ovce: 24 dana Lek se ne primenjuje kod životinja čije mleko se koristi za ishranu ljudi. Posebna upozorenja za čuvanje leka: Čuvati van domašaja dece. Čuvati u originalnom pakovanju, na temperaturi do 25˚C. Rok upotrebe u originalnom pakovanju: 2 godine. Rok upotrebe nakon prvog otvaranja: 28 dana, na temperaturi do 25˚C. Posebna upozorenja Za primenu na životinjama:Zbog poznatog antagonizma, lek ne primenjivati istovremeno sa baktericidnim antibioticima, kao što su B-laktamski antibiotici, aminoglikozidi, kombinacija sulfonamida i trimetoprima, polimiksinima. Upotreba tokom graviditeta i laktacije:Lek se ne daje u ranom graviditetu, tokom 2-3 nedelje od gestacije, kao ni u poslednjoj trećini graviditeta. Upotreba tetraciklina tokom perioda razvoja zuba i kostiju može dovesti do prebojavanja zuba i poremećaja razvoja kostiju. Kao i ostali tetraciklini, oksitetraciklin se izlučuje mlekom tretiranih životinja u laktaciji. Posebna upozorenja za osobe koje daju veterinarski lek životinjama:Osobe sa poznatom preosetljivošću na tetracikline ne bi trebalo da rukuju ovim lekom. Zbog moguće iritacije trebalo bi izbegavati direktan kontakt sluzokože i kože sa lekom. U slučaju kontakta sa kožom ili očima odmah isprati vodom. Nakon primene leka oprati ruke. Interakcije Ne primenjivati istovremeno sa baktericidnim lekovima. Posebne mere opreza pri upotrebi leka kod životinja Ako se primenjuju drugi injekcioni preparati, treba ih aplikovati na drugo injekciono mesto. Koristiti sterilne igle i špriceve. U slučaju da ukupna doza prelazi 10 ml za goveda i odrasle svinje, 5 ml za ovce i 2 ml za jagnjad i prasad, lek se mora aplikovati na više mesta. Uvek kada je to moguće, tetracikline treba davati samo na osnovu nalaza antibiograma. Posebne predostrožnosti kod odlaganja i uništavanja leka: Neiskorišćen lek ili ostatak leka se uništavaju u skladu sa važećim propisima. Način izdavanja: Lek se može izdavati samo na recept veterinara. Pakovanje: Bočica od tamnog stakla (hidrolitičke klase II), zapremine 100 ml, zatvorena gumenim zapušačem i aluminijumskom kapicom, u složivoj kartonskoj kutiji. ATCvet kod: QJ01AA06 Proizvođač: “FM Pharm” d.o.o., Subotica