http___en.fmpharm.co.rs__D0_BF_D1_80_D0_BE_D0_B8_D0_B7_D0_B2_D0_BE_D0_B4_neofloxacin-s-10_.xml
http___fmpharm.co.rs_proizvod_veterinarski-lekovi-neopen__1.xml
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Description Neofloxacin–S 10% Composition: 1 ml solution for injection contains: Enrofloxacin 100 mg Indications: Treatment of various primary and secondary bacterial infections of the respiratory, and gastrointestinall tract, in cattle and pigs. Cattle: coli-septicemia, coli-diarrhea, pasteurellosis, salmonellosis, staphylococcosis, mycoplasmosis, secondary infections in viral diseases, mastitis and others. Pigs: coli-diarrhea, coli-septicemia, salmonellosis, pasteurellosis, enzootic and bacterial bronchopneumonia, MMA syndrome and atrophic rhinitis. Contraindications: The drug is not given very young animals, or animals hypersensitive to enrofloxacin. The drug is not given to pregnant sows. Preparation should not be used in prophylaxis. Side effects: After drug administration may be associated with gastrointestinal disorders (vomiting and diarrhea), skin rash and hyper-arousal CNS. Also, it is possible photosensitization if treated animals exhibited the effects of sunlight. At the site of administration may be a transient local tissue reaction (swelling, pain, redness). Fluorinated quinolones may cause arthropathy and possibly lameness in young animals, which occurs due to damage to the articular cartilages. Are also possible allergic reactions. Target species: Cattle, calves and pigs. Dosage and method of administration: The medicine is given subcutaneously (s.c.) in the usual places or intramuscular (i.m.), (in the middle of the neck muscles) in cattle, and pigs ear. Cattle and pigs therapeutic dose ranges from 2.5 to 5 mg enrofloxacin per 1 kg of body weight, or 1-2 mL injection solution per 40 kg of body weight, depending on the severity of the infection. The drug is given at 24-hour intervals over 3-5 days. It is necessary to determine more precisely animal weight to avoid sub-dosing. Instructions for proper use of drugs: Do not give medicine to animals that do not belong to the target species. Do not give drug intavenous. If drug dose for cattle and hogs more than 10 mL, and pigs is greater than 5 mL, the drug should be given on several injection places. Use of this medicine must be based on clinical findings, and if possible results of antibiogram. Use of this drug should be limited to cases in which the cause showed resistance to other antibiotics and the bacteriological confirmation of the diagnosis and susceptibility testing of pathogens justify its use. The drug must be applied in the doses and manner prescribed, or otherwise, may be the cause of resistance to fluoroquinolones and decrease the efficiency of other quinolones in therapy because of possible cross-resistance. Withdrawal period: Meat of treated bovine animals is not for human consumption during the course of therapy and 14 days after the last application of the medicine, and the meat of pigs during the course of therapy and 13 days after the last application of the medicine. Milk of cows is not for human consumption during treatment and 7 days after last administration of the drug. Special considerations: Pregnancy and lactation: The drug is not used in pregnant animals. Special considerations for persons administering the veterinary medicinal product to animals: In applying the drug should avoid direct contact with skin and mucous membranes, or eyes. Hands after each application should be washed and medicine kept out of the reach of children. Interactions: The product should not be administered concurrently with tetracycline, macrolide antibiotics, tiamphenicol and fluorphenicol, because they all reduce or completely antagonize the effect of enrofloxacin, while simultaneously with sulphonamides and trimetoprimom, increasing its toxicity. Do not use simultaneously with theophylline because the elimination of theophylline may be delayed. Special precautions for disposal and destruction of drug Unused drug or drug residues shall be destroyed in accordance with applicable regulations. Special considerations for storing drugs: In the original container at temperatures up to 25˚C. Keep out of the reach of children. Method of issue: on prescription of veterinarian Shelf Life: In the original package 2 years. Shelf life after opening: 28 days ATCvet code: QJ01MA90 Packaging: bottle of dark glass type II of 100 mL and 500 mL, closed with bromobutyl rubber stopper and aluminum cap. Number and date of registration: Producer: “FM Pharm”, Subotica, 024/548-130
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Description Neopen Sastav: 1 mL suspenzije za injekciju sadrži Aktivna supstanca: Benzilpenicilin-prokain 300.000 i.j. Pomoćne supstance: Metilparahidroksibenzoat 1.0 mg Ostale pomoćne supstance: povidon K12; simetikon emulzija, dinatrijum-edetatt, kalijum dihidrogenfosfat i voda za injekcije. Indikacije: Lek je namenjen za terapiju primarnih i sekundarnih infekcija gastrointestinalnog, urogenitalnog i respiratornog trakta, kao i infekcija mekih tkiva i kože prouzrokovanih mikroorganizmima osetljivim na aktivnu supstancu preparata (kao što su aktinomikoza, difterija teladi, mastitis, metritis, pneumonija, infekcije rana, zarazna šepavost ovaca). Kontraindikacije: Lek se ne daje životinjama preosetljivim na peniciline i cefalosporine. Takođe, ovaj preparat se ne daje gravidnim krmačama i nazimicama, malim herbivorima i sportskim konjima 2 nedelje pre trke. Neželjena dejstva: Kod tretiranih životinja može doći do pojave reakcije preosetljivosti (alergija, anafilaksija), zatim nervnih poremećaja (ekscitacija, inkoordinacija, ataksija, povraćanje), eventualnog “vaginalnog pranja” i abortusa kod krmača i nazimica. Ukoliko primetite ozbiljno, ili bilo kakvo drugo neželjeno dejstvo koje nije ovde navedeno, o tome obavestite nadležnog veterinara. Ciljne vrste životinja: Konji, goveda, ovce, svinje, psi i mačke. Doziranje i način primene: Lek se aplikuje i.m. u dnevnoj dozi koja iznosi za: Konje i goveda: 2-3 ml / 60 kg t.m. (terapijska doza benzilpenicilin-prokaina od 10 do 15 mg/kg t.m.) Ovce: 0.5 ml / 10 kg t.m. Svinje: 1.0 ml / 10 kg t.m. Psi telesne mase od 50 kg dobijaju 5 do 6 ml leka U zavisnosti od težine infekcije terapija traje do izlečenja (obično 3-5 dana). Pre upotrebe bočicu dobro izmućkati. Uputstvo za pravilnu upotrebu leka: Ne davati lek i.v. i intratrahealno. Ako je doza leka kod goveda i konja veća od 20 mL, kod svinja od 10 mL, a kod ovaca i koza od 5 mL, lek se aplikuje na najmanje dva mesta. Moguća je alergijska reakcija kod ljudi koji dolaze u kontakt sa lekom. Pre upotrebe bočicu dobro promućkati. Karenca: Meso: goveda, ovce i svinje: 7 dana Mleko krava: 84 sata Lek se ne primenjuje kod ovaca u laktaciji niti kod konja čije se meso koristi za ishranu ljudi. Posebna upozorenja za čuvanje leka: Čuvati van domašaja dece. Čuvati u originalnom pakovanju, na temperaturi do 2-8˚C. Rok upotrebe: 1 godina. Rok upotrebe posle prvog otvaranja: 28 dana, na temperaturi do 2-8˚C. Posebna upozorenja Za primenu na životinjama: Antibiotici širokog spektra i eritromicin smanjuju antimikrobni efekat penicilina. Neomicin smanjuje resorpciju penicilina u digestivnom traktu a oksifenbutazon i probenecid smanjuju ekskreciju penicilina u bubrezima. Penicilin pojačava efekat antikoagulantnih sredstava. Metacilin, kloksacilin, cefalosporini, polimiksin B i aminoglikozidni antibiotici pojačavaju efekat penicilina. Lek se ne daje zajedno sa bakteriostatskim antimikrobnim lekovima. Upotreba tokom graviditeta i laktacije: Preparat se ne koristi kod gravidnih krmača i nazimica. Ne daje se ovcama u laktaciji čije se mleko koristi za ishranu ljudi. Predoziranje: Soli penicilina su veoma malo toksične. Životinje dobro podnose visoke doze benzilpenicilina. U slučaju ekstremno visokih doza može doći do senzibilizacije i pojave alergijskih reakcija. Inkompatibilnost: Penicilin u rastvorima precipitiraju ili inaktiviraju aminofilin, askorbinska kiselina, cefalotin, fenotijazin, natrijum hidrogenkarbonat i vitamini B kompleksa. Penicilin se postepeno inaktiviše u rastvorim aza infuziju. Kiseline, baze i oksidaciona sredstva brzo inaktiviraju penicilin. Posebna upozorenja za osobe koje daju veterinarski lek životinjama: Penicilin u 10% ljudi dovodi do hipersenzitivnih reakcija. Osobe preosetljive na penicilin ne treba da rukuju ovim lekom. Prilikom primene leka treba izbegavati direktan kontakt leka sa kožom i sluzokožom, odnosno očima. Ruke posle svake primene treba oprati i lek držati van domašaja dece. U slučaju pojave znakova preosetljivosti obrati se lekaru. Posebne predostrožnosti kod odlaganja i uništavanja leka: Neiskorišćen lek ili ostaci leka se uništavaju u skladu sa važećim propisima. Pakovanje:Unutrašnje pakovanje je ujedno i spoljašnje: Boca od obojenog stakla (II hidrolitička grupa), zapremine 100 ml, zatvorena čepom od brombutila i aluminijumskim poklopcem. Način izdavanja: Lek se može izdavati samo na recept veterinara. ATCvet kod: QJ01CE09 Proizvođač: “FM Pharm” d.o.o., Subotica