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Insomnia is a disorder characterized by the disability being unable to sleep or to sleep at all. In the long run, 10-15% of the population, more women, the elderly and the mentally ill suffer from insomnia. Disability complains that they can not fall asleep, even if they lie in bed, they wake up too soon, or that sleep is not refreshing, although sleep time is long enough. Permanent lack of sleep (chronic insomnia) is much worse than transient insomnia, which we all know. Patients with chronic insomnia have a bad mood and overall deterioration in the day, affecting their family and surroundings. They also have more injuries, traffic accidents, suicide, depression, anxiety, and immune system disorders . These textbooks can be found anywhere, for example in Saddichha2010dtc . Chronic insomnia is also a risk factor for obesity . Transient insomnia caused by stressful experiences we all know. We also all know that there is a natural biorhythm of sleep and waking that we have to respect. If our rhythm of sleep and wakefulness moves, we can adjust it with the right diet . Transient insomnia can be caused by caffeine or too much evening meal. How to get rid of insomnia When you come to a doctor with insomnia, you will most likely get so-called sleeping pills - GABA receptor agonists . These are really sedative and help you sleep. But it does not solve the cause of insomnia, which is sometimes deeper ... Identify the cause The first step is to distinguish long-term insomnia from the problems of principally others. People often say "I can not fall asleep" when they really suffer from depression, failure, unhappy love, etc. If we have these kinds of problems, we have to concentrate on solving them - the sleep problems are solved by themselves. (I 'm dealing with cases of depression here .) Watch for sedatives A naive person at the end of the 1960s might say that medical science in the 21st century will offer patients an effective and harmless cure for insomnia. When we come to the pharmacy, it looks like it at first glance - the choice of sedatives is enormous. But reality is quite different. Thousands of different sedatives have a single effect: activation of the GABA receptor, or the alcoholic drunk receptor. Like alcohol, these drugs sometimes cure. But there is also a threat to the same dependence. These drugs are unfortunately very profitable. Natural Alternatives to Insomnia Medicinal plants with sedative effect are a lot. After all, ethanol, which works just like diazepam and zolpidem, is a natural product. But we are interested in those plants that will not only succumb, but also improve the sleep mode in the long run. Ginseng improves sleep Ginseng is known as a mental stimulant , so he definitely does not belong to the hypnotic as such. Although panaxosides act on GABA receptors as well as other sedatives (diazepam, Rohypnol or alcohol), their effect is only modulated. From personal experience, I have the impression that ginseng allows sleep to be suppressed. Unlike other stimulants, however, ginseng is a calming and sleeping cycle and does not interfere with waking but improves. This was demonstrated in animals ( Lee1990cip , Huong1998aem ) and humans ( Han2013erg ). According to TČM, ginseng is soothing ( Cho2010heb ). In animal experiments it reduces anxiety from negatively motivated tasks ( Churchill2002npg , Churchill2002npg ). The calming effects of ginseng are explained by its neurosteroidal action on GABA receptors, whose ginseng activity stabilizes. At GABA receptors, the ginseng has a double, opposite effect - Yuan1998mag ginseng acts both against the increase in muscarinic activity of GABA receptors and the reduction of their activity by bikulins. According to Tsang1985gsi, the ginseng extract slows GABA reabsorption to synapses, thus prolonging the duration of GABA on the synapse. Ginsenosides Rb1, Rb2, Rc, Re, Rf and Rg1 reversibly bind to GABA A and GABA B receptors, thereby increasing sedative activity ( Kimura1994igw ). According to Takagi1972psp, the mixture of ginsenosides Rb 1 , Rb 2 and Rc prolonged hexobarbitol sleep and had a calming effect in mice. In addition, according to Cho2010heb , the sedative effect of ginseng plays a role in its action on serotonin receptors. In the words of Attele2000tia , "the results of several studies suggest that ginseng's effects can at least partly contribute to maintaining a normal sleep and wake cycle." Ginseng is not addictive - by its effects on dopamine receptors, narcotics addiction decreases ( Kim1995ibg ). Other adaptogens to improve sleep Hypnotic effects are just as easy in the plant kingdom as sedatives in pharmacies. Many plants contain GABA receptor agonists that act heavily and sedationally. Among the natural sedatives originates, for example, the heady peppermint (kava-kava) or the beer yeast , which is our favorite source of natural ethanol sedative. Popular beer yeast products are also popular with hops revolving from a miraculous family of cannabis ( Cannabaceae ) , whose positive effects on sleep confirm dozens of studies, such as Franco2012seh . When you give yourself a small, well-earned beer in the evenings before bedtime, you do not need a sedative or a sweet-hearted pepper. Satisfaction will also be provided by sage , lavender , St. John's wort, and a medical calf . Another complement of quiet sleeping can be the bayalis , the sedative herb TČM also acting through GABA receptors ( Chang2011beb ). - Glossy gloss improves and deepens sleep (rat, 22207209).
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Nesanica je poremećaj koji karakterizira nesposobnost da uopće ne može spavati ili spavati. Dugoročno, 10-15% stanovništva, više žena, starijih osoba i mentalno bolesnih pate od nesanice. Invaliditet se žali da ne mogu zaspati, čak i ako leže u krevetu, prerano se probude, ili da san ne osvježava, iako je vrijeme za spavanje dovoljno dugo. Trajni nedostatak sna (kronična nesanica) mnogo je gore od prolazne nesanice, koju svi znamo. Pacijenti s kroničnom nesanicom imaju loše raspoloženje i ukupno pogoršanje na dan, koji utječu na njihovu obitelj i okolinu. Imaju i više ozljeda, prometne nesreće, samoubojstvo, depresija, anksioznost i poremećaji imunološkog sustava . Ti se udžbenici mogu naći bilo gdje, primjerice u Saddichha2010dtc . Kronična nesanica je također faktor rizika za pretilost . Prolaznu nesanicu uzrokovanu stresnim iskustvima koje svi znamo. Svi znamo da postoji prirodni bioritam spavanja i buđenja koji moramo poštovati. Ako se naš ritam sna i budnosti pomiče, možemo ga prilagoditi pravilnom prehranom . Prolaznu nesanicu može uzrokovati kofein ili previše večernjih obroka. Kako se riješiti nesanice Kada dođete do liječnika s nesanicom, najvjerojatnije ćete dobiti takozvane tablete za spavanje - agoniste GABA receptora . To su stvarno sedative i pomažu vam spavati. Ali to ne riješi uzrok nesanice, što je ponekad dublje ... Utvrdite uzrok Prvi korak je razlikovanje dugotrajne nesanice od problema uglavnom drugih. Ljudi često kažu "Ne mogu zaspati" kada doista pate od depresije, neuspjeha, nesretne ljubavi itd. Ako imamo takve probleme, moramo se usredotočiti na njihovo rješavanje - problemi spavanja sami se rješavaju. (Ovdje se bavim slučajevima depresije .) Pazi na sedative Naivna osoba krajem šezdesetih mogla bi reći da će medicinska znanost u 21. stoljeću pružiti pacijentima učinkovit i bezopasan lijek za nesanicu. Kada dođemo u ljekarnu, to izgleda kao na prvi pogled - izbor sedativa je ogroman. Ali stvarnost je sasvim drugačija. Tisuće različitih sedativa ima jedan učinak: aktivaciju GABA receptora ili alkoholnog pijanog receptora. Kao i alkohol, ti lijekovi ponekad liječe. No postoji i prijetnja istoj ovisnosti. Ovi lijekovi su nažalost vrlo profitabilni. Prirodne alternative na nesanicu Ljekovite biljke s sedativnim učinkom su puno. Uostalom, etanol, koji djeluje poput diazepama i zolpidema, prirodni je proizvod. Ali mi smo zainteresirani za one biljke koje će ne samo umrijeti, već i dugoročno poboljšati način spavanja. Ginseng poboljšava san Ginseng je poznat kao mentalni stimulans , tako da on definitivno ne pripada hipnotičkoj kao takvoj. Iako panaxozidi djeluju na GABA receptore, kao i druge sedative (diazepam, Rohypnol ili alkohol), njihov učinak je samo moduliran. Iz osobnog iskustva imam dojam da ginseng dopušta da se san spriječi. Za razliku od ostalih stimulanata, ginseng je umirujući i spavaći ciklus i ne ometa buđenje, ali se poboljšava. To je pokazano kod životinja ( Lee1990cip , Huong1998aem ) i ljudi ( Han2013erg ). Prema TČM, ginseng je umirujući ( Cho2010heb ). U pokusima na životinjama smanjuje anksioznost od negativno motiviranih zadataka ( Churchill2002npg , Churchill2002npg ). Smirujući učinci ginsenga objašnjavaju se njegovim neurosteroidnim djelovanjem na GABA receptore, čija se aktivnost ginsenga stabilizira. Kod GABA receptora, ginseng ima dvostruki, suprotan učinak - Yuan1998mag ginseng djeluje protiv povećanja muskarinskih aktivnosti GABA receptora i smanjenja njihove aktivnosti bikulina. Prema Tsang1985gsi, ekstrakt ginsensa usporava ponovnu pohranu GABA u sinapse, čime se povećava trajanje GABA na sinapsi. Ginsenosidi Rb1, Rb2, Rc, Re, Rf i Rg1 reverzibilno se vežu na GABA A i GABA B receptore, čime se povećava sedativna aktivnost ( Kimura1994igw ). Prema Takagi1972psp, mješavina ginsenosida Rb1, Rb2 i Rc produžila je heksobarbitol spavanje i imala je umirujući učinak kod miševa. Osim toga, prema Cho2010heb , sedativni učinak ginseng igra ulogu u djelovanju na serotonin receptore. Riječi Attele2000tia recenzije, "rezultati nekoliko studija sugeriraju da efekti ginsenga mogu barem djelomično doprinijeti održavanju normalnog ciklusa sna i budi". Ginseng nije zarazan - njegovim učincima na receptore dopamina, ovisnost o drogi se smanjuje ( Kim1995ibg ). Ostali adaptogeni za poboljšanje spavanja Hipnotički učinci jednako su jednostavni u biljnom kraljevstvu kao sedativi u ljekarnama. Mnoge biljke sadrže agoniste GABA receptora koji djeluju snažno i sedacijski. Među prirodnim sedativima potječe, primjerice, mrljica za pivo (kava-kava) ili pivo kvasac , koji je naš omiljeni izvor prirodnog etanolnog sedativa. Popularni proizvodi od pivskog kvasca također su popularni kod hmelja koji se okreću od čudesne kanabisne obitelji ( Cannabaceae ) , čiji pozitivni učinci na spavanje potvrđuju desetke studija, kao što je Franco2012seh . Kada se uvečer dajte malom dobro plaćenog piva prije spavanja, ne trebate sedativ ili slatko srce. Zadovoljstvo će osigurati i kadulja , lavanda , sv. Ivana i liječnički tele . Drugi dopuna mirnog spavanja može biti bayalis , sedativna TČM biljka koja također djeluje kroz GABA receptore ( Chang2011beb ). - Sjajni sjaj poboljšava i produbljuje san (rat, 22207209).