http___hr.adaptogens.com_c-13839.aspx_1.xml
1.1 1.2 1.3 1.4 2.1 3.1 3.2 3.3 4.1 5.1 5.2 5.3 6.1 7.1 7.2 7.3 7.4 7.5 8.1 9.1 10.1 10.2 11.1 12.1 13.1 14.1 14.2 14.3 14.4 14.5 14.6 14.7 14.8 14.9 14.10 15.1 16.1 16.2 16.3 16.4 16.5 16.6 16.7 17.1 18.1 18.2 18.3 18.4 18.5 18.6 19.1 20.1 20.2 20.3 20.4 20.5 21.1 22.1 22.2 22.3 22.4 22.5 22.6 22.7 23.1 24.1 24.2 24.3 24.4 24.5 24.6 24.7 24.8 24.9 24.10 25.1 26.1 26.2 26.3 26.4 27.1 27.2 27.3 27.4
The history of adaptogenes discovered by Israel Brechman follows the theoretical and medical concept of stress , whose exponent was Janos (Hans) Selye . Before I go on, I will ask - have you ever heard the term " theoretical medicine "? Because I did not meet him in my childhood in any medical book, or later in my studies of physiology at the UK. Theoretical biology is a legitimate science that lectures on the UK and theoretical physics is the everyday concept ... Theoretical Counter Practical Science Luckily, my task is to reject the definition of science, but the good common sense tells me that "the most science" is physics, then biology and then medicine. Furthermore, intuition tells me that theoretical physics is the real physics, while experimental physics is her maid (though honored). So it seems that the science that physics is undoubtedly the theory needs, or is based on. Theoretical biology If I do not have common sense in biology, I will hear that theoretical biology is an exotic but recognized discipline. It's like an image of a distracted professor - on the one hand, a little "useless", on the other hand, offering profound insights that would give biologists the opportunity to topple the giant physicists who are publishing in biological journals and who have mastered our own field. Biology would like to be based on its own theory beyond physical chemistry, but it has not been successful in practice - despite the heroic efforts of Wilson, Prigozins and Žabotinsky. Theoretical medicine However, the peer review of medicine will be quite negative. I hear that theoretical medicine is a puffy concept, exotic discipline, at best some kind of introduction to medicine, that every particular illness has a specific aetiology and therapy, that the true theory of medicine is molecular medicine, that cheering attracts laziness and charlatans ... Moreover my intuition it seems that one day - sometimes from the 1930s to the 1960s - theoretical medicine was viewed more seriously, whereas today theoreticians are more concerned with the lack of interest that reflects the declining interest in science in general, which is a reflection ... but I would already be getting into the field of money and that does not belong here. In order to find out what others think about theoretical medicine, I copied the words "theoretical medicine" into the search engine after writing this paragraph. Snippets from results: - "For example, while theoretical medicine seeks to address the causes of health and illness, practical medicine simply tries to keep people healthy." - Or: "Theoretical Medicine = Biomedicine" (read: theoretical medicine does not exist) - Or, "The theoretical medicine, lifted out of life, did not help the sick much." (from the history of medicine, here ) - One professor (Mikuláš Popovič, born in 1941, Mukachevo) has a theoretical medicine among his specialties. - Even in the information giant called Wikipedia, the "Theoretical Medicine" page does not exist (even in the English version), again we find only a handful of professors, the year of the 40s. Fate of the Forgotten Branch So it seems that I was not so far from the truth. Medicine likes to say science, but when it comes to breaking the bread, it follows the principles of craftsmanship. The original thoughts of the founders of theoretical medicine, like Jánosz / Hans Selye with stress, or even Israel Brechman with an adaptogen , are forgotten. Students of medicine will meet the concepts of theoretical medicine in introductory lectures, but theoretical medicine as a discipline, to the extent I hear, practically ceased to exist. Stress and adaptogen folk in fashionable words, and hurrying experimenters do not have time for theory. For example, Marina Davidov, in his review "Eleutherococcus senticosus as an adaptogen - a closer look", collected detailed information about his phytochemistry, but the theoretical and medical meaning of the concept of adapogen is already missing. She had time to get acquainted with only her version of it, which she promptly rejects. In the case of stress, Gerald Weissman's "The Experimental Pathology of Stress: Hans Selye to Paris Hilton," where Weissman Selye mocks as the frontman of "stressed" Paris Hilton, his theoretical the work declares self-esteem, and its practical attempts - the only one to which it can not deny value - are reduced by reference to previous authors. But Weissman is not an inability to understand anything but fun - Selye is just one of the hundreds of satire victims, whom the old man regularly enjoys himself and his audience. In doing so, he inadvertently demonstrates how "normal" medicine is looking at theoretical medicine. Einstein in medicine is not welcome? It was just the Weissman article, which brought me to the parallel between Sely and Albert Einstein. Weissman fervently reveals what is happening in respectable resources ( ) we do not always know - that Selye has prevented Stress and Strains of Homeostasis (1935) from stressing Stress and Strains of Homeostasis (1935), while Selye's flagship publication, "A syndrome produced by various nocuous agents" discovered in Nature one year later. It also points to older experiments dealing with corticosteroids in stressful situations. It made me think. Even with Einstein, one could point to the previously known Lorentz transformation - that the discovery was already "hanging in the air". But a genius had to come to make it a coherent theory. After all, Konrad Lorenz's envious criminals claim that his imprinting at the house does not tell the peasants anything new and Isaac Newton that apples fell long before gravity laws ... The theorists blame yourself for self-promotion In his life, Selye wrote more than 1,500 papers and scientific reviews, roughly the same as his countryman Pál Erdös, the most productive mathematician of all time. Why so much? Was it just for self-realization, how does Weissman suspect? I think it was an effort to grasp hard to grasp. He faced a similar problem as Doc. Anton Markos , who in his lectures on theoretical biology still repeats the same words, and recommends reading thousands of pages , even though he is trying to single-digitize the gene and get rid of the slogan that "the gene is a nucleotide sequence in DNA." Ignore the audience Jánosz / Hans Selye was a productive experimentator. In rats exposed to various stressful factors, in addition to a specific response, the non-specific general response syndrome (Selye's own induction) demonstrated adrenal enlargement, lymph node enlargement, thymus reduction, and hormonal changes. He has developed a systematic classification of steroid hormones for corticosteroids (adrenal hormones), androgens and estrogens. He introduced the term glucocorticoid and described the anti-inflammatory effect of corticoids several years before this fact was clinically confirmed ( Szabo2012lhs ). However, I do not consider the introduction of new words, nor the research of specific hormones, as Selye's greatest contribution, but the theory of stress and health that Selye describes in his publications as a unified theory of medicine and which practitioners still ignore more and more today. Nobello outside the bowl I do not know if the Nobel Prize is - as Feynman said - the second mistake of Alfred Nobel, but at least sometimes there are slaves. And I am not talking about the ridiculous price of peace for the European Commission (!), But mainly about the fact that the Nobel Committee has not dared give Einstein the theory of relativity - it has been considered a "more practical" photoelectric phenomenon. Likewise, Jánosz / Hans Selye never had the chance to get a nobel for a unified theory of medicine, just as it could not be given to genius Erdös for mathematics ... He had the chance to get it for the glucocorticoids he discovered and named. However, when the price for glucocorticoids was awarded in the 1950s, Selye was not on the list. Selye was then nominated for a nobel nine more times - unsuccessfully every time. We just live on a planet where the most prestigious scientific prize for theoretical work is not awarded. Theoretical medicine is missing today It is time to admit that I have exaggerated somewhat in the previous text. Stress theory lives, mental stress has been generalized as an allostatic burden ( Mcewen2000aal ), and immune and neurological correlates of stress are examined. Even the theoretical medicine is developing somewhere, albeit only in a very narrow circle of people interested. For example, Bengt Brülde . Although Brülde calls his discipline "Practical Philosophy", he is mostly practicing hardcore theoretical medicine ( Brulde2001gmt , Brulde2000hdc , etc.) Lewis S. Coleman has a more personal approach to theoretical medicine, see his "30 years lost in anesthesia theory" anesthesia theories). Coleman has long opened Selye's theory of stress in surgical operations and is attempting to abstain from the theory of anesthesia as a stress reliever that would otherwise make complicated surgical operations impossible. There will certainly be people who judge the physical superstructure theory for the sake of Kabbalistic calculations of degenerate dimensions, and they will also condemn Coleman's contributions. Even the abstract benefit can ultimately lead to specific changes, just as perpetuum mobile has made progress in mechanics. I'm glad to find doctors who are aware of the importance of medical theory, and when they approach Selye's relationship with the seriousness it deserves. The role of Prague in theoretical medicine and biology Albert Einstein and Jánosz / Hans Selye have a much longer common cause: they both worked in Prague. Selye studied here (at that time it was the German University of Prague), while Albert Einstein discovered a general theory of relativity 100 years ago. Because of the Austro-Hungarian origin of Jánosz Selye, his study of physiology in Prague is not surprising - in the words of biochemistry and immunologist Felix Haurowitz, "all major German doctors worked at the Medical Faculty in Prague and Würzburg." I wonder if Selye also stayed in Viničná 7 like Einstein, or down at Albert, I welcome it. Another Prague anomaly is today's Department of Philosophy and History of Natural Sciences of the Faculty of Science of the Charles University, which offers the field of Theoretical and Evolutionary Biology and where phenomenal Zdeněk Kratochvíl also works. According to Doc. Anton Markos, the establishment of this department was made possible by the atmosphere of the early 1990s and the vacuum after the abolition of the Marxist-Leninist Institute. At the faculties of the natural sciences of ordinary universities, the establishment of this type of department is otherwise something extraordinary and unusual.
1.1 1.2 1.3 1.4 2.1 3.1 3.2 3.3 4.1 5.1 5.2 5.3 6.1 7.1 7.2 7.3 7.4 7.5 8.1 9.1 10.1 11.1 12.1 13.1 14.1 14.2 14.3 14.4 14.5 14.6 14.7 14.8 14.9 14.10 15.1 16.1 16.2 16.3 16.4 16.5 16.6 16.7 16.8 17.1 18.1 18.2 18.3 18.4 18.5 18.6 19.1 20.1 20.2 20.3 20.4 20.5 20.6 21.1 22.1 22.2 22.3 22.4 22.5 22.6 22.7 23.1 24.1 24.2 24.3 24.4 24.5 24.6 24.7 24.8 24.9 24.10 24.11 25.1 26.1 26.2 26.3 27.1 27.2 27.3 27.4
Povijest adaptogens otkrio Brechman Izrael, slijedi teorijski koncept medicinske stresa , čiji je eksponent je János (Hans) Selye . Prije nego što sam i dalje, neka me pitati - jeste li ikada čuli za pojam „teoretski lijek”? Budući da sam ga upoznao u djetinjstvu ili u bilo kojoj medicinskoj knjizi, ili kasnije za cijeli studij psihologije na Sveučilištu. To je legitimno Theoretical Biology znanost koja predaje Velikoj Britaniji i teorijske fizike, dnevnog koncept ... Teoretski odnosu na praktičnoj znanosti Srećom, to nije moj zadatak improvizacija recitirati definicija znanosti, ali zdrav razum mi govori da je „većina znanost” fizike, biologije i medicine do tada. Osim toga, moja intuicija kaže da je teorijska fizika je realna fizika, eksperimentalna fizika a njezina sluškinja (iako čitanje). Tako se čini da je tipična znanost, koja je nesumnjivo fizika, teorija i zahtijeva na temelju njega. Theoretical Biology Ako vam neka zdrav razum govori za biologiju, čujem da teorijska biologija je egzotična, ali priznat disciplina. To je kao da slici rastreseni profesor - na jednoj strani malo „beskorisno”, s druge strane, nudi duboke uvide koji će nam dati možda jednom biologa i omogućuju preljev arogantne fizičare, objavljivanje u biološkim časopisima i gubitnike za to što nam se u našem području. Biologija bih na temelju vlastitih teorija iza fizikalne kemije, ali nije - unatoč herojskim naporima Wilson, Prigožinů i Žabotínských - u praksi nekoliko cvjeta. teorijska medicina Totalno negativan ali zajedničko mišljenje u medicini. Čujem da je teorijski koncept medicine je natečen, egzotični disciplina, možda u najboljem slučaju neka vrsta uvoda u medicinu da je svaka specifična bolest ima određenu etiologiju i tretman da je pravi lijek je teorija molekularne medicine koja privlači lijeni lupetati i šarlatane ... Uz moju intuiciju čini se da je u jednom trenutku - ponekad se od 30. do 60. godina 20. stoljeća - teorijska medicina zurio ozbiljno, a danas teoretičari, a susret s ravnodušnošću, koja je odraz pada interesa u znanosti općenito, što je odraz ... ali to bi ostvarili na području bankarstva i to ne pripada ovdje. Da biste saznali što teorijska medicina smatra da su drugi udario bio sam pisanje ovaj stavak, riječ „teorijska medicina” u tražilicu. Izvodi iz rezultata: - „Na primjer, dok teorijski medicina pokušava shvatiti uzroke zdravlja i bolesti, praktična medicina se jednostavno pokušava zadržati ljude zdrava.” - Ili: „Teoretski Medicina = Biomedicina” (čitaj: teorijska medicina ne postoji) - Ili „Izvorni teorijska medicina, povukao iz života da mnogi pacijenti nisu pomogli.” (Iz povijesti medicine, ovdje ) - Jedan profesor (Mikuláš Popović, b. 1941 Mukachevo) ima teoretske medicine među svojim specijalizacijama. - Čak iu bazen informacija dosegne, pod nazivom Wikipedija stranicu „Teoretski medicina” ne postoji (čak i na engleskom jeziku) Opet nalazimo samo nekoliko profesora, berba 40-ih. Sudbina zaboravljenog industrije Dakle, čini se da nisam bio tako daleko od istine. Medicina stalno govoreći joj se sviđa znanost, ali kada je u pitanju krize, i drži načela plovila. Izvorna ideja osnivača teoretske medicine, kao što je bio samo Janosz / Hans Selye stres, ili pak čak i Izrael Brechman s adaptogena , zaboravljena. Studenti medicine s teorijskim konceptima medicine susreću u uvodnih predavanja, ali teoretske medicine kao discipline, kako sam čuje praktički prestala postojati. Stres i adaptogen kolokvijalno u buzzwords i žure teorija Eksperimenti nemaju vremena. Na primjer, Marina Davidovová u svom izvješću „eleutherococcus senticosus kao adaptogen - bliži pogled” ( Sibirski ginseng kao adaptogen - bliži pogled) prikuplja detaljne informacije o svom phytochemistry, ali teoretski medicinsku značenje pojma adaptogen već izmiče. Imala je vremena da se upoznaju sa samo vulgarized verziji, koja odmah odbio. Za stres može okrenuti kao na primjeru eseja Geralda Weissmana „The eksperimentalne patologije stresa Hans Selye na Paris Hilton” (eksperimentalnu patologiju stresa: Od Hans Selye do Paris Hilton), gdje Weissman Selye ruga kao preteča „istakao je” Paris Hilton, njegova teorijska rad izjavljuje sebezviditelňování i praktični eksperimenti - što samo može zanijekati vrijednost - smanjuje se odnosi na prethodnih autora. U Weissmana ali ne i nesposobnost da razumije nešto, ali zabavno - Selye je samo jedan od stotina žrtava satire, koje je starac redovno sebe i svoju publiku zabavlja. Evo ga nesvjesno pokazuje koliko je „normalno” medicina teorijska medicina izgleda. Einstein je u medicini nije dobrodošao? Bilo je to na kraju samo Weissmanův članak koji me doveo do paralele između Selye i Albert Einstein. Weissman željno izdaje što je u respektabilni izvori ne uvijek učimo - a to je da Selye spriječiti stres riječ za najmanje godinu dana Walter B. Cannon ( naprezanja i naprezanja homeostaze , 1935), dok je Selye-ov vodeći objave „sindrom proizvodi raznolike otrovan agenti " (sindrom uzrokovan raznim štetnim agensima) pojavio u časopisu Nature godinu dana kasnije. To se odnosi na prijašnjim eksperimentima koji se bave kortikosteroida u stresnim situacijama. To je napravio mene misliti. Čak i uz Einstein mogao ukazivati na ranije poznate Lorentz transformacije - otkriće je „visio u zraku”. Ali on je došao genije da to koheretně izražena kao koherentne teorije. Čak i Konrada Lorenze zavidni tvrde da je otisak u goslings poljoprivrednika reći ništa novo, a Isaac Newton da jabuke pala davno prije zakonima gravitacije ... Krivnja teoretičar samopromocije Selye je u svom životu napisao više od 1500 članaka i istraživanja izvješća, otprilike isto kao i njegov sunarodnjak Pál Erdos, najproduktivniji matematičar svih vremena. Zašto toliko? Bilo je to samo zbog sebezviditelňování kao sumnja Weissman? Mislim da je to bio pokušaj da zgrabite nedostižan. Stajao je pred sličnim problemom, kao Doc. Anton Markos , koji je tijekom svog predavanja Theoretical Biology ponavljao iste riječi i čitanje preporučene tekstove koji se sastoje od tisuća stranica , iako je zapravo pokušava singl - gena generalizirati i odmaknuti od slogan da „gen slijed nukleotida u DNK.” ignorirati Pokusníka Janosz / Hans Selye je produktivan eksperimentator. U štakora koji su bili podvrgnuti raznim faktorima stresa uz specifične reakcije pokazao i nespecifičnog odgovora na stres (opći sindrom prilagodba - koncept koji je uveden sam Selye) povećanja nadbubrežna žlijezda, limfni čvor proširenja, smanjenje u timus i hormonalne promjene. Sastavlja sustavna klasifikacija steroidnih hormona (npr. Glukokortikoidi nadbubrežne žlijezde), androgeni i estrogeni. On skovao izraz glukokortikoida i opisuje protuupalni učinak kortikosteroida nekoliko godina prije nego što je činjenica je potvrđena klinički ( Szabo2012lhs ). Ja, ali najveća korist Selyeho ne razmotriti uvođenje novih riječi, ili istraživačkim specifičnih hormona, ali to teorija stresa i zdravlja da Selye u svojim publikacijama zove jedinstvena teorija medicine i liječnici opće prakse do danas više manje ignorirati. Nobelova nagrada iz mjesta Ja ne znam da li Nobelovu nagradu - on je rekao Feynman - Druga pogreška Alfreda Nobela, ali barem ponekad sjedio pile. A ja ne govorim o ne tako smiješno ovogodišnje nagrade za mir Europskoj komisiji, ali i da je Nobelov odbor nije usudio dati nagradu za Einsteinovoj teoriji relativnosti (!) - to mora biti „praktični”, fotoelektrični efekt. Slično Janosz / Hans Selye nikada nije imao priliku osvojiti Nobelovu nagradu za jedinstvenu teoriju medicine, jer nije bilo moguće dati Erdos genij za matematiku ... Imao je priliku da biste dobili glukokortikoida, koji otkrivenim i ime. Međutim, kada je u 50-ima je cijena glukokortikoida nagrađen, Selye nije bio na popisu. Selye je kasnije bio nominiran za Nobelovu 9 više puta - svaki put bezuspješno. Jednostavno živimo na planetu gdje je najprestižnija znanstvena nagrada teorijskog rada ne. Teoretski Medicina danas nedostaje Došlo je vrijeme priznati da sam u prethodnom tekstu malo pretjerana. Teorija stresa života, psihički stres je generalizirati kao što se. Allostatic opterećenje ( Mcewen2000aal ) ispitivanje imunološki i neurološki korelate stresa. Ja teoretski medicina razvija negdje, makar u vrlo uskom krugu kandidata. Kao što Bengt Brülde . Iako Brülde njihova disciplina pod nazivom „praktična filozofija” općenito djeluje samo hardcore teorijski medicine ( Brulde2001gmt , Brulde2000hdc itd), personalizirani pristup teoriji medicine je Lewis S. Coleman , vidjeti njegove „30 godina izgubila u teoriji anestezije” (30 izgubljenih godina teorija anestezija). Coleman nakon dugog razdoblja otvara Selye teoriju stresa kod kirurških operacija i pokušaja da se apstraktne teorije anestezije kao tretman stresa olakšavanja, što bi inače bilo teško kirurške operacije potpuno nemoguće. Tu su, naravno, ljudi koji imaju fizički superstruna teorija osuđenika naprijed samo zbog kabalistički brojeva degenerirati dimenziju i oni će osuditi i Coleman postove. Ja apstraktne prednosti, ali u konačnici može dovesti do konkretnih promjena, kao i perpetum mobile stroj navijali napredak u pogon. Drago mi je pronaći liječnika koji je važnost teorije u medicini i ostvaruju Selye referentnu pristup s ozbiljnošću koju zaslužuje. Uloga Pragu teoretske biologije i medicine Albert Einstein i Janosz / Hans Selye dijele još više stvar: Oni su oboje radili u Pragu. Selye studirao ovdje (kada je njemačka sveučilišta u Pragu), a Albert Einstein je ovdje prije 100 godina otkrio opću teoriju relativnosti. S obzirom na austrougarskog porijekla Jánosze Selyeho je fiziologija u Pragu ne čudi - riječi biokemičar i imunolog Felix Haurowitz „svi glavni njemački liječnici radili na Medicinskom fakultetu u Pragu te u Würzburgu.” Pitam se je li Selye je također ostao u Viničné 7 kao Einstein ili dolje za Alberta, pojašnjenje dobrodošlice. Još jedna anomalija Prague danas Odjel za filozofiju i povijest znanosti Prirodoslovno-matematički fakultet koji nudi specijalizaciji teorijski i evolucijske biologije, a koja također ima fenomenalan Zdeněk Kratochvíl . Prema riječima doc. Antona Markoše je osnivanje ovog odjela omogućen atmosferu ranih 90-ih godina 20. stoljeća, a vakuum nakon ukidanja Zavoda za marksizam-lenjinizam. Fakulteti prirodnih znanosti običnog sveučilišta trebala postaviti ovu vrstu odjela ili nešto neobično i izuzetno.