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CHEMMART BISOPROLOL Bisoprolol fumarate Consumer Medicine Information What is in this leaflet This leaflet answers some common questions about bisoprolol. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you using this medicine against the benefits they expect it will have for you. If you have any concerns about taking this medicine, talk to your doctor or pharmacist. Keep this leaflet with your medicine. You may need to read it again. What this medicine is used for Chemmart Bisoprolol contains the active ingredient bisoprolol fumarate. Bisoprolol is used to treat heart failure. It is usually used in combination with other medicines. Heart failure occurs when the heart muscle is weak and unable to pump enough blood to supply the body’s needs. Heart failure may start off with no symptoms, but as the condition progresses patients may feel short of breath and notice swelling of the feet and ankles due to fluid build up. Bisoprolol belongs to a group of medicines called beta-blockers. These medicines work by affecting the body’s response to some nerve impulses, especially in the heart. As a result, it decreases the heart’s need for blood and oxygen and therefore reduces the amount of work the heart has to do. Bisoprolol also slows your heart rate, which in turn increases the efficiency of your heart. Bisoprolol can help to reduce the number of heart failure episodes needing hospital admission and also the risk of sudden death. Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed this medicine for another reason. Bisoprolol is not recommended for use in children, as the safety and efficacy in children have not been established. This medicine is available only with a doctor’s prescription. There is no evidence that this medicine is addictive. Before you take this medicine When you must not take it Do not take this medicine if you are hypersensitive to or have had an allergic reaction to bisoprolol or any of the ingredients listed at the end of this leaflet. Some of the symptoms of an allergic reaction may include cough, shortness of breath, wheezing or difficulty breathing; swelling of the face, lips, tongue, throat or other parts of the body; rash, itching or hives on the skin; fainting or hayfever-like symptoms. If you think you are having an allergic reaction do not take any more of the medicine and contact your doctor immediately or go to the Accident and Emergency department at the nearest hospital. Do not take bisoprolol if you have any of the following heart problems: severe heart failure that is not controlled medically worsening heart failure requiring injection of medicines into a vein cardiogenic shock, a serious heart condition causing low blood pressure and circulatory failure certain heart conditions where the electrical activity controlling your heart rate does not work properly, causing a very slow heart rate or uneven heart beating low blood pressure. Do not take bisoprolol if you have any of the following medical conditions: severe asthma or severe chronic obstructive lung disease (COPD) severe blood circulation problems in your limbs (such as Raynaud’s syndrome), which may cause your fingers and toes to tingle or turn pale or blue untreated phaeochromocytoma, a rare tumour of the adrenal gland metabolic acidosis, a condition when there is too much acid in the blood Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering. If it has expired or is damaged, return it to your pharmacist for disposal. Before you start to take it Tell your doctor if you are allergic to any other medicines, foods, dyes or preservatives. Tell your doctor if you are pregnant or plan to become pregnant. Bisoprolol may affect your developing baby if you take it during pregnancy. Your doctor will discuss the risks and benefits whilst taking it during pregnancy. Tell your doctor if you are breastfeeding or wish to breastfeed. Bisoprolol is not recommended while breastfeeding. Your doctor will discuss the risks and benefits of taking this medicine when breastfeeding. Tell your doctor if you have or have had any of the following medical conditions: asthma, difficulty breathing or other lung problems certain heart diseases such as disturbances in heart rhythm or Prinzmetal angina diabetes any allergic conditions psoriasis, a skin disease with thickened patches of red skin, often with silvery scales thyroid disorder any blood vessel disorder causing poor circulation in the arms and legs kidney problems liver problems phaeochromocytoma, a rare tumour of the adrenal gland. Your doctor may want to take special care if you have any of the above conditions. Tell your doctor if you are going to have anaesthesia (for example, for surgery). Bisoprolol may influence how your body reacts to this situation. If you have not told your doctor about any of the above, tell them before you start taking this medicine. Taking other medicines Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop. Taking bisoprolol may change the effect of some medicines, and some medicines may affect how well bisoprolol works. You may need different amounts of your medication or to take different medicines. Do not take the following medicines with bisoprolol without special advice from your doctor: certain anti-arrhythmic medicines such as disopyramide, lidocaine, phenytoin or flecainide, used to treat irregular or abnormal heartbeat certain calcium antagonists such as diltiazem or verapamil, used to treat high blood pressure and angina certain medicines used to treat high blood pressure such as clonidine, methyldopa or moxonidine. However, do not stop taking these medicines without checking with your doctor. Check with your doctor before taking the following medicines with bisoprolol: anti-arrhythmic medicines such as amiodarone, used to treat irregular or abnormal heartbeat calcium antagonists such as felodipine or amlodipine, used to treat high blood pressure and angina certain medicines used to treat arthritis, pain or inflammation, such as ibuprofen or diclofenac eye drops for glaucoma treatment insulin and oral drugs for diabetes anaesthetic agents used in surgery certain medicines used to increase cardiac output, such as digoxin ergot derivatives, medicines commonly used to treat migraines rifampicin, a medicine used to treat tuberculosis tricyclic antidepressants barbiturates, medicines used to treat epilepsy phenothiazines, medicines used to treat some mental conditions mefloquine, a medicine used to treat malaria certain medicines used to treat allergic reactions and nervous system disorders, such as adrenaline certain medicines used to treat depression called monoamine oxidase inhibitors, such as phenelzine or tranylcypromine. Your doctor may need to check your condition more frequently. Your doctor or pharmacist have more information on medicines to be careful with or avoid while taking bisoprolol. How to take this medicine Follow carefully all directions given to you by your doctor or pharmacist. Their instructions may be different to the information in this leaflet. How much to take The usual starting dose is 1.25 mg once daily for a week. If well tolerated, your doctor will gradually increase your dose over the next ten weeks. The usual dose for maintenance therapy is 10 mg once daily. If your conditions worsen, or you no longer tolerate the drug, it may be necessary to reduce the dose again or to interrupt treatment. In some patients a maintenance dose lower than 10 mg may be sufficient. Your doctor will tell you what to do. Your doctor will monitor your blood pressure, heart rate and other vital signs carefully after you start treatment with bisoprolol and during dose increase. Follow all directions given to you by your doctor and pharmacist carefully. How to take it Swallow your tablet(s) with a glass of water. Do not crush or chew the tablets. If you crush or chew the tablets, they will not work as well. When to take it Take bisoprolol in the morning, with or without food. How long to take it To properly control your condition, bisoprolol must be taken every day, usually as a long-term treatment. Continue taking your medicine for as long as your doctor tells you. It is very important that you do not stop taking bisoprolol suddenly. Make sure you have enough to last over weekends and holidays. If you forget to take it If it is almost time for your next dose, skip the missed dose and take your next dose as usual. Otherwise, take it as soon as you remember, and then go back to taking it as you would normally. Do not take a double dose to make up for missed doses. This may increase the chance of you experiencing side effects. If you have trouble remembering to take your medicine, ask your pharmacist for some hints to help you remember. If you take too much (overdose) If you think that you or anyone else may have taken too much of this medicine, immediately telephone your doctor or the Poisons Information Centre (Tel: 13 11 26 in Australia) for advice. Alternatively go to the Accident and Emergency Department at your nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Symptoms of an overdose may include slowed heart rate, difficulty breathing, marked drop in blood pressure, severe heart failure, or a decrease in blood sugar. While you are taking this medicine Things you must do Before starting any new medicine, tell your doctor or pharmacist that you are taking this medicine. Tell all the doctors and pharmacists treating you that you are taking this medicine. If you become pregnant or are planning to become pregnant while taking this medicine, tell your doctor. If you are to undergo anaesthesia and/or surgery, including dental, tell your doctor or pharmacist that you are taking this medicine. If you are being treated for diabetes, make sure you check your blood sugar level regularly and report any changes to your doctor Bisoprolol may change how well your diabetes is controlled. It may also cover up some of the symptoms of low blood sugar, called hypoglycaemia, such as fast heartbeat. Bisoprolol may make hypoglycaemia last longer. Your dose of diabetic medicines, including insulin, may need to change. If you are to have any medical tests, tell your doctor that you are taking this medicine. Bisoprolol may affect the results of some tests. Go to your doctor regularly for a check-up. Your doctor may check your eyes, thyroid, lipid and blood glucose levels. Tell your doctor if, for any reason, you have not taken your medicine exactly as prescribed. Your doctor may think it is not working effectively and change your treatment unnecessarily. Things you must not do Do not stop taking this medicine or change the dosage, without checking with your doctor. Stopping bisoprolol suddenly may cause your condition to worsen or other heart complications may occur. If you have to stop treatment, your doctor will usually advise you to reduce the dose gradually. Do not give this medicine to anyone else, even if they have the same condition as you. Do not use this medicine to treat any other conditions unless your doctor tells you to. Things to be careful of Be careful driving or operating machinery until you know how bisoprolol affects you. Bisoprolol may cause tiredness, dizziness or light-headedness in some people, especially after the first dose. If any of these occur, do not drive, operate machinery or do anything else that could be dangerous. Be careful getting up from a sitting or lying position. Dizziness, light-headedness or fainting may occur, especially when you get up quickly. Getting up slowly may help. Suggestions to help manage your condition Physical activity – regular exercise when symptoms are absent or mild helps improve heart function. Before starting any exercise, ask your doctor for advice. Weight reduction – your doctor may suggest losing some weight to help lessen the amount of work your heart has to do. Diet – eat a healthy low fat diet which includes plenty of fresh fruit and vegetables, bread, cereals and fish. Also, try to eat less fat and sugar. Salt restriction – too much salt can make your heart failure worse. Try to avoid using salt in cooking and at the table. Side effects Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking bisoprolol, or if you have any questions or concerns. Do not be alarmed by the following lists of side effects. You may not experience any of them. Bisoprolol helps most people with heart failure, but it may have effects in a few people. All medicines can have side effects. Sometimes they are serious, most of the time they are not. Tell your doctor if you notice any of the following and they worry you: tiredness, feeling weak dizziness headache sleep disturbances, nightmares nausea, vomiting diarrhoea, constipation feeling of coldness or numbness in hands or feet allergic runny nose hair loss sexual problems. Tell your doctor as soon as possible if you notice any of the following: muscular weakness or cramps dizziness or light-headedness (sometimes with fainting), especially on standing up, which may be due to low blood pressure irregular heartbeat e.g. a very slow heart beat symptoms of worsening heart failure such as, shortness of breath, fatigue, swelling chest pain or tightness hallucinations depression irritation or redness of the eye skin reactions such as rash, flush, itching, worsening of psoriasis difficulty hearing liver disorders such as, abnormal liver test results, yellowing of the skin and poor appetite symptoms of an allergic reaction including cough, shortness of breath, wheezing, difficulty breathing, swelling of the face, lips, tongue or throat, rash, itching, hives on the skin, fainting, or hayfever-like symptoms. The above list includes serious side effects that may require urgent medical attention. Tell your doctor immediately or go to Accident and Emergency at the nearest hospital if you experience any of the above. Other side effects not listed above may occur in some patients. Tell your doctor if you notice any other effects. Storage and disposal Storage Keep your medicine in its original packaging until it is time to take it. If you take your medicine out of its original packaging it may not keep well. Keep your medicine in a cool dry place, away from light, where the temperature will stay below 25°C. Do not store your medicine, or any other medicine, in the bathroom or near a sink. Do not leave it on a window sill or in the car. Heat and dampness can destroy some medicines. Keep this medicine where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines. Disposal If your doctor or pharmacist tells you to stop taking this medicine or they have passed their expiry date, your pharmacist can dispose of the remaining medicine safely. Product description What Chemmart Bisoprolol looks like 1.25 mg: A white to off white, round, biconvex tablet, debossed ‘1.25’ and plain on the other side 2.5 mg: A white to off white, round, biconvex tablet, debossed ‘2’ bisect ‘5’ and plain on the other side 3.75 mg: A white to off white, round, biconvex tablet, debossed ‘3.75’ and plain on the other side 5 mg: A white to off white, round, biconvex tablet, debossed ‘5’ on the left of a break line and plain on the other side 10 mg: A white to off white, round, biconvex tablet, debossed ’10’ on the left of a break line and plain on the other side Blister packs of 7, 10, 28, 30, 42, 56 and 100 tablets Ingredients Each tablet contains 1.25 mg, 2.5 mg, 3.75 mg, 5 mg or 10 mg of bisoprolol fumarate as the active ingredient. It also contains the following inactive ingredients: colloidal anhydrous silica microcrystalline cellulose croscarmellose sodium sodium starch glycollate (type A) magnesium stearate This medicine is gluten-free, lactose-free, sucrose-free, tartrazine-free and free of other azo dyes. Australian Registration Numbers Chemmart Bisoprolol 1.25 mg tablet (Blister pack): AUST R 182121. Chemmart Bisoprolol 2.5 mg tablet (Blister pack): AUST R 182118. Chemmart Bisoprolol 3.75 mg tablet (Blister pack): AUST R 182124. Chemmart Bisoprolol 5 mg tablet (Blister pack): AUST R 182125. Chemmart Bisoprolol 10 mg tablet (Blister pack): AUST R 182111. Sponsor Apotex Pty Ltd 16 Giffnock Avenue Macquarie Park, NSW 2113 Australia This leaflet was last updated in:
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Tablete za hipertenziju bisoprolol, Beta blokatori za liječenje visokog tlaka (hipertenzije) | Cochrane Djelatna tvar u lijeku Kordobis je bisoprolol fumarat. Kordobis 1,25 mg tableta sadrži 1,25 mg bisoprolol fumarata. Kordobis 2,5 mg tableta sadrži 2,5 mg bisoprolol fumarata. Kordobis 5 mg tableta sadrži 5 mg bisoprolol fumarata. Kordobis 10 mg tableta sadrži 10 mg bisoprolol fumarata. Kratkoća daha hipertenzije tvari: celuloza, mikrokristalična; silicijev dioksid, koloidni, bezvodni; karmelozanatrij, umrežena; natrijev škroboglikolat, vrste A; magnezijev stearat. Kako Kordobis izgleda i sadržaj pakiranja? Kordobis 1,25 mg tablete su bijele do gotovo bijele, okrugle, bikonveksne tablete. Kordobis 2,5 mg tablete su bijele do gotovo bijele, okrugle, bikonveksne tablete s razdjelnom crtom na jednoj strani. Kordobis 5 mg tablete su bijele do gotovo bijele, okrugle, bikonveksne tablete s razdjelnom crtom hipertenzija adolescent je jednoj strani. Bisprolol tablete (1,25/2,5/5/10mg) – Uputa o lijeku Kordobis 10 mg tablete su bijele do gotovo bijele, okrugle, bikonveksne tablete s razdjelnom crtom na jednoj strani. Samo Kordobis 2,5 mg, Kordobis 5 mg i Kordobis 10 mg tablete se mogu prepoloviti. Kordobis 1,25 mg tablete dostupne su u pakiranju od po 20 tableta u blisteru, u kutiji. Kordobis 2,5 mg, Kordobis 5 mg, Kordobis 10 mg tablete dostupne su u pakiranju od po 30 tableta u blisteru, u kutiji. Kako čuvati Kordobis? Budite oprezni s Bisoprolol-om Prije uzimanja lijeka, recite liječniku: ako imate dijabetes. Bisoprolol može prikriti uobičajene simptome niske razine šećera u krvi. Ovaj lijek čuvajte izvan pogleda i dohvata djece. Lijek ne zahtjeva posebne uvjete čuvanja. Kordobis se ne smije upotrijebiti nakon isteka roka valjanosti navedenog na pakiranju. Rok valjanosti odnosi se na zadnji dan navedenog mjeseca. Primjena Što je Kordobisi za što se koristi? Djelatna tvar lijeka Kordobis je bisoprolol koji pripada skupini lijekova koji se nazivaju beta- blokatori. Beta blokatori za liječenje visokog tlaka (hipertenzije) Ova skupina lijekova utječe na tjelesni odgovor na neke živčane impulse, osobito u srcu. Kao rezultat, bisoprolol usporava otkucaje srca i povećava učinkovitost srca kao pumpe. Bisoprolol: Uses and Expert Advice by Dr. Sameer Gupta (Cardiologist) I 1mg Pritom, srce može raditi bolje, uz manje zahtjeve za krvi i kisikom. Kordobis se koristi za liječenje: stabilnog kroničnog, umjerenog do teškog zatajenja srca Do zatajenja srca dolazi kada je srčani mišić oslabljen i nije u mogućnosti pumpati dovoljno krvi za potrebe tijela. Kordobis se primjenjuje za liječenje stabilnog kroničnog zatajenja srca. Obično se primjenjuje u kombinaciji s drugim lijekovima prikladnim za liječenje ovog stanja ACE smjernice za hipertenzije, diureticima ili srčanim glikozidima. Uvijek uzmite ovaj lijek točno onako kako Vam je rekao Vaš liječnik. Provjerite sa svojim liječnikom ili ljekarnikom ako niste sigurni. Kordobis treba uzimati ujutro, uz obrok ili neovisno o obroku. Tablete treba progutati cijele, s tekućinom, i ne smije ih se žvakati ni drobiti. Niže su navedene uobičajene doze: Stabilno kronično zatajenje srca Liječenje Kordobisom zahtijeva redovno praćenje od strane Vašeg liječnika. - Čime sniziti visoki tlak - Ckoлbko Tыcяч или MиллиoHoB лeT, пoдyMaл ЭлBиH, пocлeдoBaTeли yчиTeля coбиpaлиcb здecb, чToбы BoздaTb eMy пoчecTи. - Bisprolol tablete (1,25/2,5/5/10mg) – Uputa o lijeku | Upute - Kreni zdravo! - Hipertenzija bolest u ljudi - Etiologija hipertenzije patogeneze - Losartan hipertenzije - OлBиHy пoTpeбoBaлocb HekoTopoe BpeMя, чToбы пoпpиBыkHyTb k XилBapy -- пo пpичиHe, koTopyю oH He cMor бы ToлkoM oбъяcHиTb, He paHиB пpи эToM чyBcTB cыHa CиpэйHиc. - ЭлBиH пpocлeдил Heckoлbko пyлbcaций, и Bce oHи, HecMoTpя Ha eдиHый ocHoBHoй oбpaз, paзличaлиcb TpyдHooпpeдeлиMыMи пoдpoбHocTяMи. Ovo je naročito važno na početku terapije, tijekom povećanja doze i kada prestajete s liječenjem. Liječenje Kordobisom obično je dugotrajno. Odrasli i starije osobe Liječenje Kordobisom počinje niskim dozama koje se postepeno povećavaju. O povećanju doze odlučuje liječnik. Povećanje doze obično je u skladu sa sljedećim koracima: 1,25 mg bisoprolola jednom dnevno tijekom tjedan dana 2,5 mg bisoprolola jednom dnevno tijekom tjedan dana 3,75 mg bisoprolola jednom dnevno tijekom tjedan dana 5 mg bisoprolola jednom dnevno tijekom četiri tjedna 7,5 mg bisoprolola jednom dnevno tijekom četiri tjedna 10 mg bisoprolola jednom dnevno za održavanje terapije. Najviša preporučena doza je 10 mg dnevno. Ovisno o tome kako podnosite lijek, Vaš liječnik može odlučiti produljiti vrijeme između povećanja doza. Ako se Vaše stanje pogorša, ili više ne podnosite lijek, dozu će možda trebati ponovo smanjiti ili liječenje prekinuti. Nekim bolesnicima dovoljna doza održavanja terapije može biti niža od 10 mg bisoprolola. Vaš liječnik će Vam objasniti kako trebate postupiti. Ako je potreban prekid liječenja, Vaš liječnik će Vam obično savjetovati postepeno ukidanje doze jer se, u suprotnom, Vaše zdravstveno stanje može pogoršati. Hipertenzija i angina pektoris Liječenje treba započeti postupno niskim tablete za hipertenziju bisoprolol koje se potom lagano povećavaju. Liječnik će Vam individualno prilagoditi dozu, ovisno o pulsu i uspješnosti terapije. Kordobis tablete Odrasli i starije osobe Uobičajena doza je 5 mg jednom dnevno. Liječnik može povećati dozu na 10 mg jednom dnevno. Najveća preporučena doza je 20 mg jednom dnevno. - Kada je puls hipertenzije - Mjerenje krvnog pritiska kod čovjeka - To je tlak u arterijama veći od normale, najčešće bez simptoma, koji povećava rizik nastanka zatajenja srca, srčanog udara infarkta srcamoždanog udara, oštećenja bubrega i oštećenja očne pozadine krvnih žila mrežnice oka. - Biprol 2,5 mg tablete — Mediately Baza Lijekova - Beta blokatori za liječenje visokog tlaka hipertenzije Što je cilj ovog pregleda literature? - Kako razlikovati vegetativno-vaskularnu hipertenziju Primjena u djece i adolescenata Kordobis se ne preporučuje kod djece i adolescenata. Primjena u bolesnika s oštećenjem bubrega ili jetre Kod bolesnika s poremećajima rada jetre ili bubrega, blage do umjerene jakosti, u pravilu nije potrebno prilagođavanje doze. U bolesnika s teškim poremećajem bubrega ili jetre doza ne smije premašiti 10 mg jedanput na dan. Tablete za hipertenziju bisoprolol uzmete više lijeka Kordobis nego što ste trebali Odmah se javite svome liječniku ili u najbližu stanicu za hitnu pomoć. Sa sobom ponesite ovu uputu i sve preostale tablete. Znakovi predoziranja tablete za hipertenziju bisoprolol usporene otkucaje srca, otežano disanje, pad krvnog tlaka, akutno zatajenje srca i pad šećera u krvi. Ako ste zaboravili uzeti Kordobis Nemojte uzeti dvostruku dozu kako biste nadoknadili propuštenu dozu. Svoju uobičajenu dozu uzmite sljedeće jutro. Ako prestanete uzimati Kordobis Nemojte iznenada prestati uzimati lijek niti mijenjati preporučenu dozu, a da se najprije ne posavjetujete sa svojim liječnikom. - Nasljedni faktor hipertenzije - Hipertenzija tretman lječilište - Prihvaćene indikacije za beta-blokatore su: Koronarna bolest srca angina pektoris stabilna i nestabilna te infarkt srca sa ili bez ST elevacije u akutnoj i postinfarktnoj fazi Hipertenzija Aritmije supraventrikulske, ventrikulske, kontrola frekvencije klijetki pri fibrilaciji atrija Zatajivanje srca Hipertrofijska opstruktivna kardiomiopatija Ostale kardiovaskularne indikacije vazovagalna sinkopa, disekcija aorte, Marfanov sindrom, prolaps mitralne valvule, kongenitalna QT prolongacija, tetralogija Fallot, fetalna tahikardija Centralne indikacije anksioznost, esencijalni tremor, profilaksa migrene, profilaksa sustezanja alkohola Endokrine tireotoksikoza Gastrointestinalne profilaksa krvarenja iz varikoziteta jednjaka Glaukom u lokalnoj primjeni Primjena beta blokatora? - NARODNI ZDRAVSTVENI LIST - Rawel SR 1,5 mg filmom obložene tablete s produljenim oslobađanjem indapamid Indapamid svojim diuretskim djelovanjem u kortikalnom dilucijskom segmentu bubrežnih tubula i smanjenjenjem arteriolarnog i ukupnog perifernog otpora smanjuje vrijednost visokog krvnog tlaka. - Dijagnoza bolesti hipertenzije Ako morate prekinuti uzimanje lijeka, liječnik će Vas uputiti kako postepeno smanjivati dozu. U suprotnom, Vaše zdravstveno stanje bi se moglo ozbiljno pogoršati. U slučaju bilo kakvih pitanja u vezi s primjenom ovog lijeka, obratite se svom liječniku ili ljekarniku. Upozorenja i mjere opreza Tablete tablete za hipertenziju bisoprolol hipertenziju bisoprolol se svom liječniku ili ljekarniku prije nego uzmete Kordobis: ako imate bolove u prsima dok mirujete Prizmentalova anginaako imate blažu astmu ili kroničnu bolest pluća, ako imate šećernu bolest, ako ste na strogoj dijeti, ako imate ili ste prije imali tablete za hipertenziju bisoprolol ljuskav osipako imate blaže probleme s cirkulacijom u rukama i nogama, ako imate bolest bubrega ili jetre, ako su Vam otkucaji srca nepravilni, ako imate poremećaj rada štitnjače tireotoksikozaako ste trudni, ako planirate zatrudnjeti ili ako dojite. Dodatno, recite Vašem liječniku: ako ste planirani za desenzibilizacijsko liječenje npr. Djeca i adolescenti Kordobis se ne preporučuje kod djece i adolescenata. Drugi lijekovi i Kordobis Obavijestite svog liječnika ili ljekarnika ako uzimate ili ste nedavno uzeli ili biste mogli uzeti bilo koje druge lijekove. Nemojte uzimati sljedeće lijekove uz Kordobis bez posebnog savjeta Vašeg liječnika: Lijekovi za liječenje visokog krvnog tlaka, angine pektoris ili nepravilnih otkucaja srca antagonisti kalcija kao što su verapamil i diltiazem Lijekovi za snižavanje krvnog tlaka kao što su klonidin, metildopa, moksonidin, rilmenidin. Lijekovi za liječenje nepravilnog rada srca klasa I antiaritmika kao što su kinidin, disopiramid, lidokain, fenitoin, flekainid, propafenon Međutim, nemojte prestati uzimati ove lijekove bez prethodnog savjetovanja s Vašim liječnikom. Drugi lijekovi za liječenje nepravilnog rada srca antiaritmici klase III kao što je amiodaron. Lijekovi koji spadaju u skupinu beta-blokatora, a namijenjeni su za vanjsku primjenu npr. Lijekovi na recept Određeni lijekovi za liječenje npr. Alzheimerove bolesti ili glaukoma parasimpatomimetici kao što su takrin ili karbakol ili lijekovi za liječenje akutnih problema sa srcem simpatomimetici kao što su izoprenalin i dobutamin U bolesnika koji uzimaju oralne tablete za hipertenziju bisoprolol ili inzulin, upotreba lijeka Kordobis može prikriti simptome niskog šećera u krvi —hipoglikemije. Anestetici npr. Glikozidi digitalisa koji se primjenjuje pri liječenju zatajenja srca. Nesteroidni protuupalni lijekovi, kojima se liječi artritis, bol ili upala npr.