http___hr.265health.com_conditions-treatments_hormone-issues_1016123007.html_1.xml
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background Addison's disease, also called adrenal insufficiency or hypocortisolism, is a rare endocrine (hormonal) disorder that is characterized by weight loss, muscle weakness, fatigue, low blood pressure, and occasional darkening of the skin. Addison's disease is named after Dr. Thomas Addison, who first identified adrenal insufficiency in 1849. The disease occurs when the adrenal glands do not produce enough of the hormone cortisol and, in some cases, the hormone aldosterone. The adrenal glands, located just above each of the two kidneys, secrete cortisol, also called hydrocortisone. Cortisol regulates proper glucose metabolism, blood pressure, and insulin release for blood sugar maintenance and it is involved in the inflammatory response. When the adrenal glands do not produce enough cortisol, symptoms of Addison's disease develop. Aldosterone belongs to a class of hormones called mineralocorticoids. This hormone helps regulate blood pressure as well as the water and salt balance in the body by helping the kidneys retain sodium and expel potassium. When aldosterone production falls too low, the kidneys are not able to regulate the salt and water balance, subsequently causing blood volume and blood pressure to drop. Addison's disease can occur at any age, but is most common in people ages 30 to 50. Researchers estimate that about one out of 100,000 people have Addison's disease. The disease is slightly more common in females than men. Researchers estimate that the male to female ratio is about 1:1.5-3.5 Treatment for Addison's involves replacing the hormones that the adrenal glands are not producing with medication. Corticosteroids like hydrocortisone (A-hydroCort®, Cortef®, Hydrocortone®, Hydrocortone® Acetate, Hydrocortone® Phosphate, Solu-Cortef®) are used to replace cortisol. Mineralocorticoids like fludrocortisone (Florinef®) are used to replace aldosterone. Related Terms ACHT, autoimmune disease, autoimmune disorder, autoimmunity, adrenal cortex, adrenal glands, adrenal hormones, adrenocorticotropic hormone, aldosterone, corticotropin, corticotropin releasing hormone, cortisol, CRH, endocrine system, endocrinology, glucocorticoid, glucocorticoids, hormonal disorder, hormone, hormones, hydrocortisone, hypoadrenalism, mineralocorticoid, mineralocorticoids, polyendocrine, polyendocrine deficiency syndrome, primary adrenal insufficiency, Schmidt syndrome, secondary adrenal insufficiency, tuberculosis.
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Saznajte što znači da imaju Addison bolest . Vaši nadbubrežne žlijezde , koji se nalazi neposredno iznad svakog bubrega , su dodijeljen zadatak reguliranja svaki organ i tkivo u vašem tijelu . Da biste to učinili , to je potrebno za te žlijezde za proizvodnju dovoljne količine glukokortikoida i mineralokortikoidi , naime hormona kortizola i aldosterona . U Addison bolest , ova funkcija je umanjena . Prepoznajte simptome Addison bolest . Sljedeći simptomi mogu pojaviti tijekom vremena : umor, slabost mišića , gubitak težine praćene gubitkom apetita , niske razine šećera u krvi (hipoglikemija) , vrlo nizak krvni tlak , povećane pigmentacije kože i žudnja za slana jela plan na test krvi će se poduzeti kako bi se utvrdilo da li ili ne može biti pate od Addison bolest . Kalija , natrija , kortizola i adrenocorticotropic hormona ( ACTH ), izlučuje hipofiza seruma se mjeri , uz razinu protutijela prikazanog . Roll rukavu za stimulaciju ACTH Test , koji mjeri količinu kortizola u krvi prije i nakon injekcije sintetskog ACTH se primjenjuje . Niska razina kortizola izdanju , ili ih uopće , u odgovoru na sintetičkom ACTH sugerira nadbubrežne žlijezde umanjenja vrijednosti . Budite spremni za CT abdomena (poznat kao tomografija ) za gledati za strukturne abnormalnosti nadbubrežne žlijezde . Imajte na umu da je to slikanje ispitivanje se može ponoviti na Vašem hipofize , kao dobro . Očekujte još jednu injekciju , s inzulinom ovaj put . Vaš liječnik svibanj želite obaviti ovaj test da vidite kako vaše kortizon proizvodnje i razine glukoze u krvi odgovoriti na uvođenje inzulina . U normalnom funkcioniranju nadbubrežne ,prisutnost inzulina uzrokuje kortizon razine rasti i razina glukoze padne . From:http://hr.265health.com/conditions-treatments/hormone-issues/1016123007.html