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Cancer is the leading cause of death in a civilized world. A common feature of tumors is that the population of their own cells starts to breed uncontrollably at the expense of the organism. This multiplication can be stopped after a number of generations - then it is benign , such as maternal signs, adenomas, intestinal polyps, and small tumors within the body that we do not even know about. By contrast, malignant (malignant) tumor cells will never stop dividing and often have metastatic capability - spreading to distant parts of the body. Cancer in the broader sense means any malignant cancer. In the narrower sense, cancer is a malignant tumor originating from the epithelium of the skin or mucosa - carcinoma . Less common sarcoma is a malignant tumor of the connective tissue. Healthy cells have many inhibitions against unlimited division. For example, contact inhibition: The cell stops dividing when there is no free space. Then there's Hayflick's limit: most cells can not grow all the time, but it's limited to a few dozen divisions. Most body ( somatic ) cells also have the ability to divide permanently - they are terminally differentiated . The ability to divide into the body retains only a small fraction of cells - stem cells . They are activated during injury, but in some tissues they are still active. Therefore, tissues that grow and regenerate in adulthood - skin, mucosa, mammary gland, gonads ... Compared to somatic cells, tumor cells are undifferentiated. They remind stem cells - they are as young as they are, dividing and preparing to create some useful tissue, but they will never reach this end. In the beginning, tumor cells behave almost normally and retain their original function. Because of this, for example, in pituitary, adrenal, and other endocrine tumors, hormonal disorders occur because tumor cells are still dealing with their original occupation - the production of hormones. Tumor cells also, from the beginning, have a considerable desire to differentiate, ie to actually create a tissue that they are preparing to make. Often, only a mild chemical stimulus is sufficient to make the tumor cell decide to grow and become a functional, terminally differentiated somatic cell ( Kawamata2006dts ). During cancer, cancer cells lose their inhibitions and good behavior. They also learn to escape recognition by the immune system, lose apoptosis and the will to differentiate, and gradually adapt to the cytostatics the doctor is trying to heal. The development of cancer is a stochastic process of biological evolution taking place in the cancer cell population. To understand the phenomenon of malignant overthrow, it is important to remember that each malignant tumor: - It originates from a single cell of a specific tissue. - In its multiplication, evolutionary leaps stochastically progress towards greater malignancy. - Sooner or later he will confront the host's immune system. These characteristics also show why cancer is so difficult to treat. Since the beginning, cancer cells are virtually no different from normal cells, and it is hard to invent a poison that selectively kills them without damaging the whole body. The ability of cancer cells to evolve in turn means that even if a physician, by means of a substance or treatment method, keeps the disease temporarily in check, the cancer cells will develop resistance over time and the given substance / method will cease to work. For relapse, it is enough to survive the survival of one single viable cancer cell. Let us also point out that people are very well aware of the anti-cancer immunity. Man is naturally a long-lived animal and he is better equipped than most vertebrates. Throughout our lives, our immune system detects and destroys dozens of tumors without bothering to inform us. While mice and rats are dying for cancer after 1 year, dogs and cats receive cancer after 5 years, the human immune system allows us to survive 5 decades of active life in relative safety. This is our advantage, but on the other hand it also means that when the doctor comes with a malignant patient, his immune system has failed in his position and missed his best chance of applying anti-cancer immunity. The risk of cancer is rising sharply during the age of man's age, which is relatively rapid during the six decades of life. Susceptibility to cancer in old age is increasing not only because we have in DNA the damage accumulated over a lifetime, but also because of total body dyscrasias and immunity. The stochastic nature of malignancy and the course of the disease is the reason why cancer occurs only in some people and progresses differently in different patients. Cancer treatment For the reasons already mentioned, prevention and treatment of cancer will always be a difficult problem. The medical advances in the treatment of cancer are mild, despite the cost of its research. For some cancers, the likelihood of cure has increased slightly (prostate tumors, seminoma, malignant melanoma, lung, colon , stomach and esophageal cancer), in others (glioblastoma, hepatoma). Dangerous remains female females ( breast , ovary, and cervix). Cancer treatment has three standard components: - Surgical treatment - resection of the tumor bearing (bearing). - Cytostatic treatment - Destruction of cancer cells by selective poisons or radiation. - Supportive care - regeneration of the body and strengthening of the immune system In addition, biomolecule (immunotherapy), hormonal therapy, differentiation induction therapy, etc., are used, but the above 3 modalities remain crucial. Adaptogens and anticancer fungi, which I point out here, generally belong to supportive treatment, but they also lack direct cytostatic effects. While conventional surgical and cytostatic therapies are detrimental to both the tumor and the body, adaptogens promote regeneration and restore the damaged immune system. Anti-cancerous sponges have direct antitumour effects by both stimulatory effects on cytotoxic immunity and pro-apoptotic effects on cancer cells. Research on these drugs is extensive, and I provide references in the following text. Cytostatic treatment Cancer cells from healthy cells are very difficult to distinguish. In fact, the only reliable distinctive feature is that cancer cells are divided unlimitedly. And it is this property that affects cytostatic treatment. Cytostatic effect is generally any effect that damages or kills dividing cells, but is relatively harmless to resting, non-dividing cells. For example, this property has radiation. Ionizing radiation most damages the dividing cells and therefore radiotherapy is used to destroy tumors. An even more specific effect on the dividing cells has chemical cytostatics - mitotic poisons used in chemotherapy. It is, for example, 5-fluorouracil, which blocks the synthesis of thymidine - one of four DNA stones, which has no other use in the cell. Many of the cytotoxic agents used are of natural origin: Vinca alkaloids (vinblastine, vincristine), yew taxanes, podophyllotoxin, camptothecin, bacterial streptomycin, Unfortunately, many other cells are separated in addition to cancer cells and are damaged in the same way as a tumor in cytostatic treatment. They are epithelial cells of the skin, mucous membranes, growth zones of hair roots, nail beds, and stem cells of hematopoiesis, from which both red and white cells emerge. Cytostatic treatment is a terrifying experience in which patients suffer from tremendous fatigue, nausea, anorexia and loss of fertility. Hair looks and lines appear on the nails (Beau line). One of the worst consequences is a severe damage to the immune system by destroying white blood cells. Targeted cancer therapy Since the very beginning of cytostatic treatment, doctors have tried to limit this to cancer cells only. For radiotherapy, for example, a tumor bearing is targeted, while the rest of the body receives a relatively small dose. Chemotherapy has been targeting perfused organs since the 1950s. However, these methods fail with extensive metastases. In these cases, there is nowadays biological treatment (bio-therapy), more correctly immunological treatment. Cure for cancer is nothing new. There has long been an effort to create anticancer vaccines. The main problem is that the patient's own immune system is usually heavily damaged by cytostatic therapy. In today's immunotherapy, therefore, anti-cancer cells are artificially produced and administered to the patient in-house. This is a good commercial strategy, not a miraculous method. The physician actually imitates the immune system of the patient and faces a challenge in which the patient's natural immunity has failed once. Very promising is the combination of antibodies with a-radioisotopes, which then locally irradiate small tumorous deposits (targeted alpha therapy). Targeted alpha therapy has been devoted, for example, to No. 3 of Current Radiopharmaceuticals from September 2008 , from specific publications such as Tolmachev2007rth (lutetium 177 + HER2 anti -breast cancer antibodies) and Liepe2009a2a (Alpharadin, Prostate Cancer Radiation 223). Research activity is progressing intensively in this field, see Gudkov2016trt for a review. Supportive treatment of cancer Supportive treatment is not secondary to cancer. While other diseases can rely on natural regeneration capacity, cytostatic cancer therapy will immune patients' immunity and regenerative capacity thoroughly. In the body, new and new stem cells are recruited during chemotherapy, attempting to regenerate and being destroyed. The patient will become physiologically aged for several years in a few months. It also suffers from the immune system in which maternal hematopoietic stem cells are destroyed in the bone marrow. Ginseng Adaptogens protect against radiation and chemical damage and help with regeneration. These effects are scientifically documented, but it is important to ask whether cancer cells can be protected by analogy. According to experts it is not - specific adaptogens not only protect cancer cells but activate anti-cancer immunity and directly cause apoptosis of cancer cells. The direct effect against cancer cells is noticeable in anti-cancerous fungi - fungus adaptogens, which are typically glossy glossy. Again, the question is whether scientists examining adaptogens suffer from obliquity over their subject. This question exists and is being continuously addressed not only in adaptogens but also in any other sector of science. The miracle cure for cancer does not exist and is not even adapted to it. And there are restrictions that prevent scientists from finding a reliable cure for cancer. Genus Genuine is an extraordinary adaptogen suitable for cancer Ginseng research in cancer treatment focuses on 4 types of effects: (1) preventive, (2) protective and regenerative radiation and chemotherapy, (3) immunomodulatory and (4) direct anticancer, further subdivided into 3 subcategories. Preventive effects : In terms of prevention of ginseng use, it correlates negatively with the incidence of cancer ( Shin2000cpp ) and can be attributed to specific panaxosides ( Shibata2001ccp , Wang2008icp , Choi2013bbc ). A randomized clinical trial confirming this phenomenon is Yun2010npe . The anti-inflammatory effect of ginseng ( Hofseth2007ict ) may also include cancer risk factors. Protective and regenerative effects : The adaptogenic effect of ginseng against radiation damage is fully utilized in the treatment of cancer. Ginseng protects cells against irradiation, promotes regeneration of tissues and mainly the immune system ( Yonezawa1976rri , Takeda1981rri , Yonezawa1981rri , Takeda1982rri , Yonezawa1985rri ). According to clinical studies, ginseng improves the quality of life of cancer patients and limits the adverse effects of chemotherapy ( Kim2006esg , Yennurajalingam2015hag ). Immunomodulatory effects : According to Takei2008dcp , ginseng has an immunomodulatory effect acting on the cytotoxic response. It increases the activity of NK cells ( Yun1993iat , Jang2015pnk , Takeda2015ink ) and macrophages ( Wang2010ita ) and thus contributes to anticancer immunity. Direct antitumor effects : Panaxoside has been shown to have direct anti-tumor effects by Dr. Lars Christensen is divided into 3 groups: (1) cytostatic effect, (2) reduction of malignancy, and (3) limiting tumor growth in tumors ( Christensen2009gcb ). Recent reports of antitumor effects of ginseng are Wong2015rag and Wang2016rgc . The cytostatic effect is studied both in vitro on the cell lines and in vivo in animals. Numerous studies can not all be quoted, I choose: According to Wong2010age , ginseng extract was performed on a mouse model against pulmonary carcinoma. The ginseng also performed against human gastric carcinoma cells ( Hwang2015efg ), human gallbladder cancer ( Wu2015ers ), and human lymphoblastic leukemia ( Xia2016iap ) cells. Ginseng metabolite compound K acts against hepatoma cells ( Song2010imc ), ginsenoside F2 against glioblastoma in the rat model ( Shin2012aeg ), gssd. Rg 3 against human myeloma cells ( Li2016imm ) and ginseng acidic polysaccharides improved the results of cytostatic melanoma treatment in a mouse model ( Shin2004eae ). Gssd. Rg 3 and Compound K inhibit angiogenesis in lung, stomach and ovarian tumors ( Wang2015gmc ). Compound K acts by inhibition of p38 MAP kinase ( Jeong2010cib ) and sphingosine kinase 1 regulation ( Shin2014gci ). A slightly less inhibitory effect on angiogenesis has gssd. Rb 1 ( Papapetropoulos2007gor , Wang2015gmc ). Other panaxosides (eg, gssd, Rg 1 ) have opposite effects on vascular growth ( Sengupta2004may ). Although I adapt adaptogens, as a scientist, I must admit that despite all the research, the utility and irreplaceability of ginseng in cancer is not scientifically proven. It is not a question of whether or not herbal treatment of cancers - the recognized cytostatics are, for example, poisons of plant origin (vinblastine, taxol, podophyllotoxin etc., see previous section). The question is, rather, to what extent model adapters such as ginseng and aloe overshadow popularity by less well-known adaptogens suitable for cancer. So: Although I am presenting a lot of scientific resources, I urge you to try ginseng not for scientific reasons, but for some others, for example from respect for the unscientific TCE . In developed countries using TCM (typically Taiwan), ginseng is one of the most common components of prescriptions prescribed by the TCM surgery for cancer patients ( Lai2012ppc ). Glossy Glossy is a "miracle" sponge against cancer Of course, the title is not meant to be serious. Glossy gloss is an adaptogen containing a large amount of 100% non-terrestrial triterpenoid saponins - ganoderic acid, ganoderic acid, lucialdehyde, ganoderiol, and others (see Paterson2006gtf ). A total of 315 triterpenoids in the genus Ganoderma describe an overview of Xia2014crs , which is more than 182 triterpenoids described in the genus Panax ( Christensen2009gcb ). Lesklokorka also contains typically fungal B-glucans, polysaccharides and proteoglycans. Polysaccharides and other substances (e.g., polypeptides) are also considered to be carriers of the anti-rabies effects of glans. Glossy Glossy has no side effects ( Wachtelgalor2004gll , Kwok2005prd ). Lesklokorka supports cytotoxic immune response ( Radwan2011air ). Its extract and pure B-glucan (fucogalactan) increase IL-23 outflow from dendritic cells and induce Th17 T lymphocyte differentiation ( Yoshida2012pit ). Glycophage polysaccharides accelerate the proliferation of bone marrow macrophages and increase the production of IL-1B, IL-6, IL-12B35, IL-12B40, IL-18, TNFa, IL-1B and IL-12 ( Ji2011ibm ). Ganoderma formosanum activates an in vivo anticancer immune response in cancer-affected mice ( Wang2014aai ). Lesklokorka works against in-vitro colon cancer cell lines ( Thyagarajan2010tfg , Jedinak2011glt , Hong2004egl ) and reduces malignancy of gastric cancer cells ( Jang2011aae ). The direct cytotoxic effects of specific glomerular triterpenoids comment on Xia2014crs . According to Min2000tfs ganoderic acids c, d, e, z, n, and in vitro act against sarcoma and lung carcinoma cells. Ganoderic acid inhibits leukemia (HL-60) and ganoderliol E growth of breast cancer cells (MCF-7). According to Wang2010nga, ganoderic Mf, Mk and S kill lung cancer cells (95-D) and cervix (HeLa) at concentrations of 15-40uM. Ganoderic acid and lucid acids N and A act against hepatoma and leukemia cell lines ( Wu2001cgl ), ganodermic acid Ja against hepatoma cells ( Li2005gal ). Lucialdehyde B and C, ganodermanolol and ganodermanondiol act against lung cancer cells, breast cancer and sarcoma ( Gao2002nta ), luciadiol and ganoderiol F against HeLa cervical carcinoma cells ( Cheng2010ctf ), two other specific leukemia cell leukemias, cervical cancer, hepatoma and gastric cancer ( Guan2008clt ). According to Ma2012ltf , ganoderic acids A and C1 and luciformdehydes D and E, all at concentrations ~ 20ug / ml, are also anticancer. lucidum was anticancer in vivo in transplanted liver cancer ( Chen2010pg1 ) and other tumors ( Trajkovic2009apg , Nonaka2006aaa ). G. lucidum had an in vivo immunostimulatory and anti- rabbing effect ( Gao2005aau , Pang2007pnp ) and preceded the development and metastasis of lung cancer in mice exposed to cyclophosphamide carcinogen ( Nonaka2008eaf ). G. atrum had an anticancer effect on the mouse model ( Zhang2014pfg ). Ganoderic acid T reduces lung carcinoma cell malignancy in vivo ( Chen2010gai ). In terms of clinical trials, Gao2003egg tested the effect of polysaccharides of glans in 30 advanced cancer patients and found an increase in CD56 + cell count and NK cell activity. Chen2006mir found an increase in the number of CD3, CD4, CD8 and CD56 + lymphocytes in 41 patients with advanced colon cancer using glans. Sun2014pal has also found improvements in immune parameters in lung cancer patients using glossary. The study of Oka2010wef in 96 patients (+ 102 controls) found that glossopause used for 12 months prevented the development of colorectal adenomas, neoplasms of which can develop colon and rectal cancer . When using glossy cork , cases of complete cure are known, Suprasert2014ccg reports on 5 of these patients. Even more so than ginseng in glossy ice that regardless of the number of enthusiastic scientists recommending this sponge to the attention of doctors ( Sliva2003glr , Radwan2011air , Cheng2015glc , Jin2016glr ), funding of clinical trials has not been successful yet, so the main guide remains the scarlet the linguist is the magical medicine and cultural symbol. Other anticancer fungi In assessing anticancer fungi, it is advisable to avoid extremes. Both the oncologist and the patient must not wait for a miracle. When a doctor with a malignancy develops, it is clear that his immune system has already missed his best chance. Mild, even strong, immune enhancement is usually not enough to cure. On the other hand, there is a misconception that anti-cancerous fungi are ineffective and do not deserve their attributes. Such a view does not stand in the light of available scientific studies ( Popovic2013mcu ). The list of species I mention is not complete or enclosed: - Outkovka pestrá - Outfit camper - Chinese caterpillars - Rectangle oblique - chaga (an overview of its anticancer effects is Song2013pua ) - Firebird - Choroš wil The group of anticancer fungi is not distinct because even conventional edible sponges nonspecifically increase anti-cancer immunity ( Patel2012rdm , Feeney2014mhs ). Specifically, it is, for example, oyster mushroom , edible bumblebee ( Lentinus edodes , šísat), Grifola frondosa , maitake, Hericium erinaceus , and common mushrooms ( Agaricus bisporus , A. blazei ). Asian mushrooms (šítake, maitake) are not more effective than our non-specific anti-cancer effects are common fungal substances: B-glucans ( Temizoz2016vap ), ergosterol ( Li2015epf ) and fiber. Information that our soakbib, resp. his parasite does not catch golden-throat are cancer-producing is untrue . Other adaptogens for the prevention and supportive treatment of cancer Cancer is a popular topic in science. Paradoxically, precisely because of the over-popularity of the topic, it is difficult to identify truly effective anti-cancer adaptogens. To illustrate, CancerHSP ( Tao2015cah ) herbicide database contains more than 2400 potentially anticancer plants, The Duke and the TCMSP ( TC202 ) herbalist database ( Ru2014tds ) adds hundreds of herbs to it, but it is unclear which of them performs heavily and only weakly. Weak and non-specific anticancer effects are very common in herbs and fungi, but unfortunately, it is not enough to meet the hope of oncology patients. Certain anticancer effects have been found in almost all popular adaptogens, of which I offer more or less random choices: - In the genus Panax, there are types of American ginseng , ginseng notoginseng , etc., similar to P. ginseng and analogous anticancer effects (see Wang2015cap , Wang2016pap , Wang2008prg , He2012aap ). - Lycium barbarum polysaccharides (LBP) from Chinese goji fruit juice promote the growth of spleen cells ( Peng2001sci , Gan2004iaa ) and T lymphocytes ( Chen2008atl , Gan2003ppc ), immune regeneration after cytostatic treatment ( Gong2005tel ) and directly effect against liver , prostate, breast ( Chao2006hwe , Liu2000eia , Li2009lbi ). - Momordika bitter (bitter cucumber) has, in addition to the known potential against diabetes and obesity, a preventative potential for cancer, see the Raina2016pbm , Dandawate2016bmp and Nerurkar2010bma reviews . - There are hundreds of studies trying to scientifically clarify the experience of the TCM with the Baikal Shishak . Here are just a couple to illustrate: For example, bajcalin caused apoptosis of liver cancer cells ( Yu2016bps ), prostate ( Chan2000iap ) and other tumors ( Luo2014sbe ). Similarly, vogonin acts by multiple cellular mechanisms that cause apoptosis, restricts tumor growth in tumors, and has a synergistic effect with the fluorouracil ( Wu2016awe ) cytotoxic agent. In Taiwanese TCE, the bearded beetle ( Lai2012ppc , Yeh2014hdc , Chao2014ppc ) is also very commonly prescribed for cancer. - Anticorrosion activity in the liver was observed in vitro ( Huang2007maa , Huang2009czj ). - Vitania snodárna has documented anti-tumor effects ( Dar2015pow ), for example due to its inhibitory effect on vascular growth ( Mohan2004wip ). - The Chinese angel (angel angel) had anticancer effect in vitro and in vivo ( Cheng2004aea , Tsai2005aea , Kan2008sae , etc.). His polysaccharides were active against three in vivo mouse models of cancer ( Shang2003esa ). China is the most commonly prescribed TCH herb against breast cancer ( Lai2012ppc ) in Taiwan, but its effect is unclear from a scientific point of view ( Chang2006mhe ). - The anti- rabies effects of the sacred basil analyze the Baliga2013osh overview. - In vivo ( Shimpo2014iel , Pan2013iag and others) anticancer and polysaccharides from aloe vera have anticancer effects in vitro ( Xu2016rse , Luo2014caw , Chen2016ent , Chihara2015eae , Hussain2015avi , Yonehara2015ave ) and in vivo ( Shimpo2014iel , Pan2013iag and others), a good overview of the anticancer properties of aloe is Harlev2012apa , aloe-emodin anthraquinone . According to Lai2012ppc, TCHM practice in Taiwan, in addition to ginseng and jelly, often uses the plants of Vladimiria souliei , cardamom , pinnate , kosinec , Forsythia suspensa, and cymica daty . According to the Radomskalesniewska2015apr review, the effect on the growth of blood vessels in stomach tumors is pink , purple , aloe, and Plumbago zeylanica . Bocharova1994tpe also emphasizes the stairway . Safarzadeh2014hmi also contains anti- rabbit ginger , saffron , curcumin, and xanthorrhizol from turmeric , resveratrol, kvercetin and genistein from legumes, bajkalein and other flavonoids from Baikal Shihak , Shrimp, Isatis tinctoria , Sophora flavescens, and red-eyed ( Tabebuia impetiginosa ). Poisonous natural cytostatics Adaptogens contrast with natural mitotic poisons from some poisonous plants. They kill both cancerous, as all the other dividing cells and in the treatment of cancer are commonly used. They are not adaptogens because they are badly damaged by the healthy organism. I mention them for the sake of completeness, they are all very dangerous natural poisons. Typically used are vinblastine and vincristine from Vinca minor , taxol (paclitaxel) from yew ( Taxus baccata ), Camptothecin camptothecin ( Camptotheca acuminata ), Podophyllum peltatum podophyllotoxin. This category includes probably also a very promising, venomous Tripartite wilford ( Tripterygium wilfordii ), an average poisonous mistletoe ( Viscum album ) with its proteoglycans (lectins) and other plants. Recently, it has also been reported that the fruits of the Australian tree Hylandia dockrillii of the rust family have strong cytostatic effects (see ). However, the herbs described in this paragraph are completely out of the definition of the adaptogen and must be used by MUDr. doctor. The specific types of cancer I will be more concerned with - Leukemia (blood cancer) - Lung cancer - Stomach cancer - Malignant melanoma
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Rak je vodeći uzrok smrti u civiliziranom svijetu. Zajednička značajka raka je da se stanovništvo vlastite stanice počinje višestruko nekontrolirano na štetu organizma. Ova proliferacija može nakon određenog broja generacija prestaje - onda je benigni tumor (dobroćudni), kao što su madeži, adenoma, polipoza kolona i malih tumora unutar tijela, čije postojanje ne shvaćaju. Nasuprot tome, raka stanice (maligni) tumori nikada ne prestaju podjele i često imaju sposobnost da metastaza - širenje u udaljenim dijelovima tijela. Raka u širem smislu odnosi se na bilo malignih tumora. U užem smislu, karcinom je maligni tumor koji proizlaze iz epitela kože ili sluznice - karcinoma. Manje česta sarkom je rak vezivnog tkiva. Zdrave stanice imaju mnoge prepreke protiv neograničenog podjele. To je kao kontakt inhibicije: Cell prestane dijeliti, oni prolaze nema prostora. Zatim tu je Hayflick granica: većina stanica ne može rasti cijelo vrijeme, ali je ograničen na nekoliko desetaka podjele. Najviše tijelo (somatskih) stanica ima sposobnost da trajno podijeliti OFF - su fazi diferencirane. Sposobnost da dijele svoje tijelo zadržava samo mali dio stanica - matične stanice. Oni se aktiviraju ozljede, ali u nekim tkivima su još uvijek aktivni. Rak su stoga skloni oni tkiva koje rastu u odrasloj dobi i regenerirati - koža, sluznica, mliječne žlijezde, gonade ... Odnosu somatske stanice su nediferencirane stanice raka. Oni podsjećaju matičnih stanica - ako su mladi, dijeljenjem i priprema za stvaranje korisne tkivo, ali da cilj nikada neće odrasti. Tumorske stanice su posebno na početku ponašaju gotovo normalno i držite još svoju izvornu funkciju. Zbog toga, na primjer, tumora hipofize, nadbubrežne žlijezde i drugih endokrinih poremećaja hormonskih doći jer su tumorske stanice još bavi izvornom zanimanja - proizvodnja hormona. Tumorske stanice su također posebno na početku ponašaju velike želje da se razlikovati, tj. Doista stvaraju tkiva za čije je stvaranje on vjeruje plinovoda. Često samo blagi kemijski podražaj na tumorske stanice odlučila rasti i postati funkcionalna, terminalno diferenciranim somatskih stanica ( Kawamata2006dts ). Tijekom raka kancerogene stanice njihove inhibicije i pristojan ponašanje postupno izgubiti. Uče se također izbjeći prepoznavanje od strane imunološkog sustava, apoptoza gube sposobnost i volju da se diferenciraju i postupno prilagoditi na citostatike koje liječnik pokušava izliječiti rak. Razvoj raka toliko je stohastički proces biološke evolucije odvija u populaciji stanica raka. Da bismo razumjeli fenomen maligne degeneracije je važno shvatiti da svaki rak: - Ona dolazi izvorno iz jedne stanice određenog tkiva. - Tijekom njegova razmnožavanje nastavlja stohastički evolucijski skok prema povećanom malignosti. - Prije ili kasnije to će se natjecati s imunosnog sustava domaćina. Od tih svojstava ukazuju na to i zašto je to tako teško za liječenje raka. stanice raka gotovo od samog početka, jer ne razlikuje od normalnih stanica i da je teško razmišljati o toksina koji bi selektivno ubiti, a nije štetan za cijelo tijelo istovremeno. Sposobnost stanica raka proći evoluciju pak znači da čak i ako je liječnik korištenjem metode tvari ili liječenja čuvati bolesti u uvali privremeno, stanice raka mogu razviti otpornost tijekom vremena i Dana Latka / metoda prestaje raditi. Recidivi dovoljno da pokušaju liječiti jedan preživio samo održive stanice raka. Također je vidljivo da ljudi rade u pogledu imuniteta protiv raka vrlo dobro. Čovjek je, naravno, dugovječna životinja i rak je opremljena bolje od većine kralježnjaka. Tijekom života našeg imunološkog sustava prepoznaje i uništava desetke tumora, bez da nas obavijestite. Dok miševi i štakori umiru od raka nakon samo jedne godine, psi i mačke dobiti rak i nakon 5 godina, ljudski imunološki sustav omogućuje nam relativno sigurno od raka preživi pet desetljeća aktivnog života. To je u našu korist, ali s druge strane, to također znači da kada je riječ o medicinskim pacijentima koji su razvili malignosti, pa je njegov imunološki sustav nije uspio u svojoj funkciji i njihovu najbolju priliku da se prijave imunitet protiv raka propustili. Rizik od raka povećava oštro u starosti, koja kod ljudi dolazi relativno oštro više od 6 desetljeća života. Osjetljivost na rak u starosti se povećava ne samo zato što nose oštećenja DNA akumulirane tijekom života, ali i zbog ukupnog pogoršanja u tijelu i imunitet. Stohastičke prirode maligne degeneracije i bolesti je razlog zašto rak pojavljuje samo u nekim ljudima i različitim pacijentima napreduje različitim brzinama. liječenje raka Iz razloga što je već spomenuto u prevenciji i liječenju raka je uvijek težak problem. Medicinski napredak u liječenju raka, unatoč troškova nastalih u istraživanju skroman. Za neke vrste raka blago povećava vjerojatnost lijek (tumora prostate, seminom, malignog melanoma, pluća, debelog crijeva , jednjaka, želuca i), ali ne i s drugim (glioblastom, hepatoma). Opasni ostaju ženske raka ( dojke , jajnika i rak vrata maternice). liječenje raka ima tri standardne komponente: - Kirurških obrada - odstranjivanja tumora ležajevi (ležajevi). - Citostatik terapija - uništavanje selektivni otrova staničnih ili zračenja. - Potporno liječenje - regeneracija tijela i ojačati imunološki sustav Osim toga, to se odnosi bioléčba (imunoléčba), hormonsku terapiju, liječenje indukcijom diferencijacije i sl, ali gore navedene tri modaliteta i dalje presudno. Adaptogens i gljive protiv raka, koji su istaknuti, pripadaju uglavnom podržavaju tretman, ali nema ih nedostatak ili izravno citostatik učinak. Dok konvencionalni kirurških i citostatik terapija djeluje destruktivno na tumor i tijela, regeneraciju podršku Adaptogens i obnavljanja oštećenih imunološki sustav. Antitumorski gljive imaju izravan antitumorski učinak kao stimulacijski učinak na citotoksične imuniteta i proapoptotska učinak na stanice raka. Istraživanje tih lijekova ponovno opsežna i ispod njega dati reference. citostatik liječenje stanice raka iz zdravih stanica je vrlo teško razlikovati. Uglavnom, jedini pouzdani Posebnost je da su stanice raka podijeliti na neodređeno vrijeme. A to utječe na njihovu vlasništvu liječenjem sa citostaticima. Citostatski učinak je uglavnom bilo posljedica koje štete ili ubija diobu stanica, ali je relativno bezopasan za mirnim, koje se dijele stanice. Ovaj objekt ima primjer zračenja. Ionizirajućem zračenju oštećuje najviše diobu stanica te stoga koristi zračenje za uništavanje tumora. Još specifični učinak na diobu stanica, ali uz kemijski citostatik - mitotičkih otrova koji se koriste u kemoterapiji. To je, na primjer 5-fluorouracil, koji inhibira sintezu timidina - jedan od građevnih blokova četiri DNA u stanici nema drugog korištenja. Mnogi citostatici upotrijebiti prirodnog porijekla vinka alkaloidi (vinblastin, vinkristin), taksane iz tise, podofilotoksin, kamptotecin, bakterijska streptomicina itd Nažalost, osim stanica raka u tijelu podijeljen brojnim drugim stanicama, a oni su oštećeni od strane liječenjem sa citostaticima, kao i tumor u cijelosti. Oni su epitelne stanice kože, sluznica, zone rasta korijena kose, noktiju kreveta i također hematopoetskih matičnih stanica, koje proizlaze iz crvene i bijele krvne stanice. Citostatik tretman je zastrašujuće iskustvo, u kojoj pacijenti pate ogroman umor, mučnina, gubitak apetita i gubitak plodnosti. Kosa ispadne i tu su linije na noktima (Beauovy linija). Jedan od najgorih posljedica teškog oštećenja imunološkog sustava uništavanjem bijelih krvnih stanica. Ciljana terapija raka Liječnici od samog početka terapije sa citostaticima pokušao to nekako ograničen na stanice raka. Na primjer, radioterapija namjerno ozračena s tumorom, a ostatak tijela dobiva relativno malu dozu. Za kemoterapije od 50-tih godina 20. stoljeća, provodi ciljano perfuziju zahvaćenih organa. No, ove metode ne uspiju za velike metastaza. U tim slučajevima, tu se sada zove. Biološka terapija (bioléčba) ispravno imunološka obrada. Rak Bioléčba nije ništa novo. Davno je bilo nastojanje za stvaranje cjepiva protiv raka. Glavni problem je u tome što pacijenta vlastiti imunološki sustav obično se teško oštetile terapije sa citostaticima. Trenutno, dakle imunoléčbě antitijela protiv stanica karcinoma, a proizvode se umjetno primjenjuje intravenski na pacijentu. To je dobra poslovna strategija, ali ne i čudesan način. Liječnik zapravo samo oponaša pacijenta imunološki sustav i time stoji pred izazovom, koja ima prirodni imunitet nakon što je pacijent nije uspjelo. Vrlo obećavajući je kombinacija protutijela na a-radioizotopa koji se zatim lokalno ozračivanja tumora mali žarišta (ciljana terapija alfa). Ciljane a terapija je posvećena primjeru br. 3. Tekući radiofarmaka rujna 2008. , od posebne publikacija npr Tolmachev2007rth (lutecij-177 HER2 protutijela protiv raka dojke ) i Liepe2009a2a (Alpharadin, radij 223 karcinom prostate). Istraživanje aktivnosti u ovom području napreduje intenzivno, za pregled vidi Gudkov2016trt . Podržavaju liječenje raka Zaštitna terapija nije lijek za rak sekundarne. Dok je u drugim bolestima može se rabiti prirodne regenerativne sposobnosti, citostatik liječenje imuniteta kod oboljelih i regenerativne sposobnosti temeljito uništen. U tijelu tijekom kemoterapije i novo zapošljavanje novih matičnih stanica koje se pokušavaju obnoviti i time su uništeni. Pacijent za nekoliko mjeseci fiziološki dobiva stariji godine. Kao što je dobro patiti imunološki sustav, u kojem je iz temelja uništio roditeljske stanice koštane srži. Adaptogens vrsta ginsenga štiti od zračenja i kemijskih oštećenja i pomoći u oporavku. Ti njihovi učinci su znanstveno dokumentirana, ali je prikladno pitati da li analogija neće zaštititi stanice raka. Prema stručnjacima, to nije - specifični adaptogens ne štite samo stanice raka, već naprotiv aktiviraju imunitet protiv raka i izravno uzrokuje apoptozu stanica raka. Izravno djelovanje protiv stanica karcinoma je značajan za antitumorski gljivica - gljivica adaptogens obilježen Lingzhi gljiva. Opet, pitanje je da li su znanstvenici istražuju adaptogena pate pristranosti prema svom predmetu. Ovo pitanje postoji i stalno se riješiti samo s adaptogena, ali iu svakoj grani znanosti. Čudesna lijek za rak postoji i to nije ni adaptogens. I oni možda postoje ograničenja koja sprečavaju znanstvenike izmisliti pouzdan lijek za rak. Ginseng adaptogen izvanredno prikladni rak Istraživanja ginseng za liječenje raka se od četiri vrste učinaka: (1) sprječavanje i (2) za zaštitu i za jačanje tijekom ozračivanja i kemoterapijom, (3), imunomodulatora i (4), koji izravni antitumorska dalje podijeliti u tri potkategorije. 1. preventivno djelovanje: Sa stanovišta sprečavanja uporabu ginsenga negativno koreliraju s incidencijom raka ( Shin2000cpp ) preventivni učinak protiv raka može se pripisati određenoj panaxosidům ( Shibata2001ccp , Wang2008icp , Choi2013bbc ). Kliničke studije koje potvrđuju ovu pojavu je Yun2010npe . Čimbenici koji smanjuju rizik od raka mogu uključivati protuupalni učinak ginsenga ( Hofseth2007ict ). Zaštitne i regenerativne učinke na rak u potpunosti su primjenjivi adaptogeni učinak ginsenga protiv oštećenja izazvanih zračenjem . Ginseng tijekom ozračivanja štiti stanice potiče regeneraciju tkiva i uglavnom imunološki sustav ( Yonezawa1976rri , Takeda1981rri , Yonezawa1981rri , Takeda1982rri , Yonezawa1985rri ). Prema kliničkim studijama, ginseng poboljšava kvalitetu života pacijenata oboljelih od raka i smanjuje nuspojave kemoterapije ( Kim2006esg , Yennurajalingam2015hag ). Treće Imunomodulacijski učinci: Prema Takei2008dcp ima ginseng imunomodulatorne učinke koji se pojavljuju prema citotoksične reakcije. Povećava aktivnost NK stanica ( Yun1993iat , Jang2015pnk , Takeda2015ink ) i makrofaga ( Wang2010ita ) i time doprinosi otpornosti protiv raka. Izravni antitumorski efekti su otkrivene U panaxosidů direktan učinak protiv tumora Dr. Lars Christensen podijeljeni u tri skupine: (1) citostatik učinak, (2) smanjenje malignosti, i (3) ograničavaju rast krvnih žila u tumorima ( christensen2009gcb ). Nedavni izvještaji antitumorsko djelovanje ginsenga su Wong2015rag i Wang2016rgc . Citostatski učinak je istraživan je in vitro na staničnim linijama i in vivo na životinjama. Brojne studije ne mogu citirati sve, biram nasumce: Prema Wong2010age izvodi ekstrakta ginsenga u mišjem modelu protiv raka pluća. Ginseng također izvodi na ljudskim stanicama karcinoma želuca ( Hwang2015efg ), humani raka žučnog mjehura ( Wu2015ers ) i ljudskih stanica, akutna limfoblastična leukemija ( Xia2016iap ). Ginseng metabolita spoj A , protiv stanica hepatoma ( Song2010imc ) ginsenoside F2 prema modelu štakora (glioblastom Shin2012aeg ) gssd. Rg 3 protiv ljudskih stanica mijeloma ( Li2016imm ) i kisele polisaharide ginseng poboljšanih rezultata terapije sa citostaticima u mišjem modelu melanoma ( Shin2004eae ). Gssd. Rg 3 i spoj koji inhibira angiogenezu kod raka pluća, želuca, jajnika i ( Wang2015gmc ). Spoj djeluje inhibiranjem p38 MAP kinazu ( Jeong2010cib ) i kontrolu sfingozin kinazu 1 ( Shin2014gci ). Nešto manje inhibicijski učinak na angiogenezu je gssd. Rb 1 ( Papapetropoulos2007gor , Wang2015gmc ). Još panaxosidy (npr npr gssd, Rg 1 ), a oba imaju suprotne učinke na rast krvnih ( Sengupta2004may ). Iako adaptogens promovira kao znanstvenik moram priznati da unatoč svim istraživanjima korisnosti ili nezamjenjiv raka ginseng nije znanstveno dokazano. To još nije ovdje pitanje da li je biljni tretman raka da ili ne - nakon svega, priznati citostatika mnogo slučajeva otrovi biljnog podrijetla (vinblastina, taksola, podofilotoksina itd, vidi prethodni odjeljak). Pitanje je, naprotiv, u mjeri u kojoj je model Adaptogens kao ginseng i aloe njegova popularnost zasjenila manje poznatih adaptogena prikladno rak. Dakle: Iako sam spomenuo puno znanstvenih resursa, pozivam vas pokušao ginseng, a ne za znanstvenih razloga, ali za neke druge, poput poštivanja neznanstvene TCM . U razvijenim zemljama koriste TCM (obično Tajvan) Ginseng je jedan od glavnih sastojaka smjese recept u TCM klinikama za pacijente s rakom ( Lai2012ppc ). Lingzhi gljiva je „čudo” gljiva protiv raka Naslov očito nije mislio ozbiljno. Reishi sjaj je Adaptogen sadrži veliku količinu od 100% nezázračných triterpenoid saponina - ganoderové kiselina ganoderenové kiselina lucialdehydy, ganoderioly i više (vidi Paterson2006gtf ). Ukupno 315 triterpenoidi roda Ganoderme pregled opisuje Xia2014crs , što je više od 182 triterpenoidi opisane u rodu panax ( christensen2009gcb ). Reishi gljiva obično dalje sadrži beta-glukana, polisaharide i proteoglikane. Pod antikancerogenih učinaka nositelja još Reishi polisaharidi i druge tvari (na primjer, polipeptida). Lingzhi gljiva nema nuspojava ( Wachtelgalor2004gll , Kwok2005prd ). Reishi podržava citotoksični imunološki odgovor ( Radwan2011air ). Ekstrakt i čisti B-glukan (fukogalaktan) povećava IL-23 izlijevanje dendritične stanice i T-stanice inducira diferencijaciju Th17 ( Yoshida2012pit ). Polisaharidi Reishi ubrzavaju proliferaciju makrofaga koštane srži i povećava proizvodnju IL-1, IL-6, IL-12p35, IL-12p40, IL-18, TNF-a, IL-1B i IL-12 ( Ji2011ibm ). Ganoderma formosanum aktivira antitumorsko imuni odgovor in vivo u miševa s rakom ( Wang2014aai ). Reishi je učinkovit protiv staničnih linija za karcinom debelog crijeva u uvjetima in vitro ( Thyagarajan2010tfg , Jedinak2011glt , Hong2004egl ) i ograničava malignosti želučanih stanica raka ( Jang2011aae ). Izravni citotoksični učinci Reishi triterpenoidi gljiva specifična komentari Xia2014crs . Prema Min2000tfs ganoderové kiselina, Y, δ, e, Z, n, θ i in vitro protiv stanica sarkoma i raka pluća. Ganoderová kiselina, Jc inhibira rast stanica leukemije (HL-60) i porast E ganoderiol stanica karcinoma dojke (MCF-7). Prema Wang2010nga ganoderové kiselina Mf MC i S uništava stanice raka pluća (95-D) i cerviksa (HeLa) u koncentracijama 15-40 um. Ganoderová kiselina, E lucidenové kiselina, N i učinkovit je protiv stanične linije leukemije i hepatoma ( Wu2001cgl ) ganodermová kiselina ja od hepatoma stanica ( Li2005gal ). Lucialdehyd B i C i ganodermanonol ganodermanondiol protiv stanica raka pluća, dojke i rak sarkoma ( Gao2002nta ) luciadiol i ganoderiol F na HeLa stanicama raka grlića maternice ( Cheng2010ctf ), dva određenije lanostanoidy protiv stanica leukemije, karcinom grlića maternice, hepatoma i karcinom želuca ( Guan2008clt ). Prema Ma2012ltf antitumorska i ganoderové kiseline i C1 lucialdehydy D i E, a sve u koncentracijama ~ 20 ug / ml. G. lucidum raka djelovao in vivo u miševa transplantiranih s rakom jetre ( Chen2010pgl ) i drugih oblika raka ( Trajkovic2009apg , Nonaka2006aaa ). G. lucidum je imunostimulatorni in vivo i učinak protiv zračenja ( Gao2005aau , Pang2007pnp ) i spriječi formiranje i metastaziranja raka pluća miševa koji su izloženi u karcinogenom ciklofosfamid ( Nonaka2008eaf ). G. atrum radio modela raka miša ( Zhang2014pfg ). Ganoderová kiselina T smanjuje maligna stanica raka pluća (in vivo Chen2010gai ). Što se tiče kliničkih ispitivanja, Gao2003egg testirali učinak Reishi polisaharida na 30 bolesnika s uznapredovalim rakom i otkrili povećanje broja CD56 + stanica i aktivnost NK stanica. Chen2006mir se u 41 pacijenata s naprednim rakom debelog crijeva tretirani s povećanjem Reishi CD3, CD4, CD8 i CD56 + limfocita. Sun2014pal opet vidio napredak u imunoloških parametara u bolesnika s rakom pluća tretirana sa reishi. Studije Oka2010wef 96 bolesnika (kontrola + 102) utvrdio da Reishi koristite starije od 12 mjeseci sprečava razvoj adenoma kolona, od kojih su neoplazme može razviti rak debelog crijeva i rektuma . Kada uzimanje reishi su poznati slučajevi potpunog oporavka, Suprasert2014ccg izvješća o tih 5 pacijenata. Čak i više nego ginseng s reishi je istina da bez obzira na broj entuzijasta znanstvenika preporučuju ovu gljivu na pažnju liječnika ( Sliva2003glr , Radwan2011air , Cheng2015glc , Jin2016glr ), financiranje kliničkih ispitivanja za nju nije impresioniran, pa je misao vodilja opet ostaje šarlatan TCM za što je reishi (ling-chi) čaroban lijek i kulturni simbol. Drugo antikancerogeno gljive U procjeni antikancerogeno hub je poželjno da se izbjegne krajnosti. Onkolog, niti pacijent od njih ne bi trebao čekati čudo. Kada je u pitanju liječnik s pacijentom razvio malignosti, jasno je da je njegov imunološki sustav je propustio svoju najbolju šansu. Umjereno, čak i jaki poticaj imunitet obično nije dovoljno da se izliječi. S druge strane, zabluda da gljive protiv raka nedjelotvorni i njegov epitet zaslužuju. Takvo mišljenje u svjetlu raspoloživih znanstvenih studija ne stand up ( Popovic2013mcu ). Popis vrsta koje se spominje nije potpun ili zatvoren: - Trametes versicolor - versicolor kamfor - cordyceps - Inonotus obliquus - CagA (pregled svojih anti-raka učinaka Song2013pua ) - Ohňovec plug - Choros Oris antitumorski gljive skupina nije jasna, kao i konvencionalni jestivih gljiva specifično povećavaju antitumorski imunitet ( Patel2012rdm , Feeney2014mhs ). Naime, na primjer kamenice , shiitake (Lentinula edodes. Shiitake), zec gljiva (zec gljiva, maitake), šiljat koralja (Hericium erinaceus), ali i obični šampinjona (Agaricus bisporus, A. blazei), vidi Xu2012cpe , Martin2010ccs . Azijski gljivice (Shiitake, maitake) nisu učinkoviti od našeg, nespecifično nosač antikancerogenih učinaka u stvari zajedničke gljivičnih sredstava: P-glukana ( Temizoz2016vap ), ergosterolni ( Li2015epf ) i vlakana. Informacije koje naše vrganj, respektivno. parazit nedohub zlatovýtrusý kancerogene je lažna . Ostali adaptogens podržati prevenciju i liječenje raka Rak je popularna tema u znanosti. Paradoksalno, zbog prevelike popularnosti predmeta teško je zapravo odrediti učinkovite antikancerogena adaptogena. Za ilustraciju, u antikancerogenih učinaka bilja CancerHSP ( Tao2015cah ) sadrži više od 2.400 potencijalnih antikancerogene biljke, ethnobotanical baze podataka, dr vojvoda i baza podataka TCM bilja TCMSP ( Ru2014tds ) dodati stotine bilja, ali nije jasno koji od njih djeluju snažno i da samo malo. Slabe i nespecifičnim učinke protiv raka u stvari sa začinskim biljem i gljivama vrlo česte, nego ispuniti nade pacijentima raka, na žalost, nije dovoljno. Određene antitumorski efekti su pronađeni u gotovo sve popularne adaptogena, od kojih svi nude više ili manje slučajan izbor: - U roda Panax vrste imaju ginseng američki , ginseng notoginseng sl sl sastav analogne P. ginseng i antikancerogena svojstva (vidi popis Wang2015cap , Wang2016pap , Wang2008prg , He2012aap ). - Kustovnica polisaharidi (LBP) od voća goji (Goji) potiče proliferaciju stanica slezene ( Peng2001sci , Gan2004iaa ) i T limfociti ( Chen2008atl , Gan2003ppc ) rekuperacija imunosti nakon tretmana (citostatik Gong2005tel ) i direktno na stanice raka jetre , prostate dojke ( Chao2006hwe , Liu2000eia , Li2009lbi ). - Balsam apple gorka (gorko krastavac) ima pored poznatog potencijala protiv dijabetesa i pretilosti preventivno potencijal protiv raka, vidi izvješća Raina2016pbm , Dandawate2016bmp i Nerurkar2010bma . - Postoje stotine studija koje pokušavaju znanstveno objasniti iskustva sa TCM Sisak bajkalským . Spomenuti samo za ilustraciju: Na primjer bajkalin izaziva apoptozu stanica raka jetre ( Yu2016bps ), prostate ( Chan2000iap ) i drugih oblika raka ( Luo2014sbe ). Slično vogonin djeluje nekoliko mehanizama uzrokuje stanične apoptoze, inhibira rast krvnih žila u tumorima i ima sinergistički učinak s citostaticima fluorouracila ( Wu2016awe ). U Tajvanski TCM često propisane posebno raka također kapica bradatog ( Lai2012ppc , Yeh2014hdc , Chao2014ppc ). - Za Cicimku datulja pronađen na jetru antitumorski učinak in vitro ( huang2007maa , huang2009czj ). - Dovikom snodárná dokumentirala antitumorsko djelovanje ( Dar2015pow ), na primjer, s obzirom na njihov inhibitorni učinak na rast krvnih žila ( Mohan2004wip ). - Kineski (Angelica kineskog) imaju antikarcinomsku aktivnost in vitro i in vivo ( Cheng2004aea , Tsai2005aea , Kan2008sae itd) polisaharidi plesali protiv tri modela raka kod miševa in vivo ( Shang2003esa ). Divlji Angelica kineski na Tajvanu TCM biljka najčešće propisane od raka dojke ( Lai2012ppc ), ali znanstveno je nejasno učinak ( Chang2006mhe ). - Antitumorski efekti bosiljak sveta raspravlja pregled Baliga2013osh . - Antrakinoni i polisaharidi iz Aloe vera raka-nitro čin ( Xu2016rse , Luo2014caw , Chen2016ent , Chihara2015eae , Hussain2015avi , Yonehara2015ave ) i in vivo ( Shimpo2014iel , Pan2013iag i drugi), dobar pregled protiv raka svojstva Aloe je Harlev2012apa , antrakinona Aloe-emodin je posvećen pregled Chen2014pae , Prema Lai2012ppc TCM praksa u Tajvanu osim Ginseng i Wild Angelica se često koristi Vladimiria souliei biljka, kardamom , pinelii tri lista , milkvetch Membranozni , plačući forzicija (forzicija suspensa) i žižule . Prema izvješću Radomskalesniewska2015apr ima učinak protiv rasta krvnih žila u tumorima Rhodiola rosea , ljubičasta Coneflower , aloe vera i Leadwort Lanke (grafit zeylanica). Rhodiola također naglašava Bocharova1994tpe . Prema izvješću Safarzadeh2014hmi ima limfna đumbir pravu , šafran , kurkuma i xanthorrhizol od kurkumovníku , resveratrol, kvercetin i genistein iz mahunarki, bajkalein i drugih flavonoida iz Siska Baikal , Uncaria tomentosa , Isatis tinctoria (Isatis tinctoria), pagoda stablo žućkaste (Sophora flavescens) i trans crveni (Tabebuia impetiginosa). Otrovni prirodni citostatici Za razliku od prirodnih Adaptogens mitoze, otrovi nekih otrovnih biljaka. Oboje ubiti rak kao i bilo koje druge dijeljenjem stanica i u liječenju raka obično koriste. To nije adaptogens, jer zdravo tijelo jako štetan. Ja to spominjem samo za potpunost, oni su svi vrlo opasni otrovi. Među najčešće koriste su vinblastin i vinkristin Vinca minor (Vinca minor), taksol (paklitaksel) sa tise (Taxus baccata) -kamptotecina u kamptoteky ostrolisté (Camptotheca acuminata), podofilotoksin (iz noholistu štítnatého Podophyllum peltatum). U ovoj kategoriji su vjerojatno vrlo obećavajući, otrovna trojkřídlec wilfordův (Tripterygium wilfordii), malo otrovne imela (Viscum album) sa svojim proteoglikana (lektini) i drugih biljaka. Nedavno je također izvijestio da je australska voćka iz obiteljskih Hylandia dockrillii pryšcovitých imaju jake cito učinke (vidi, ovdje ). Ne znam, međutim, ako Hylandia adaptogen i njezin utjecaj jamčiti ... Određene vrste raka, koje ću posvetiti više - Leukemije (rak krvi) - rak pluća - raka želuca - maligni melanom