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Healthy cells have many barriers against unlimited division. It's as contact inhibition: Cell stops sharing when it is not about space. Then there is the Hayflick limit which limits the majority of the cells on a relatively small number of division. Most of the body (ie. Somatic) cell has the ability to divide completely disabled. Then in the body retains only a small fraction of cells - stem cells. The cancer are therefore prone those tissues that grow into adulthood and regenerate - skin, mucous membranes, mammary gland, gonads ... In summary, we can say that every cancer: - Based originating from a single cell of a particular tissue. - In its multiplication proceeds stochastically evolutionary leaps towards greater malignancy. - Sooner or later it will compete with the host immune system. During aging accumulate mutations in the DNA. The cancer are therefore more vulnerable older people. Procedure cancer is a random process, which varies from patient to patient. We humans are naturally long-lived and cancer are better equipped than most vertebrates. Over the life of our immune system detects and destroys dozens of tumors without bothering to inform us. Cancer can therefore look as well as immunodeficiency . cancer treatment Despite medical advances in cancer treatment still remains a difficult medical problem. For some cancers, the likelihood of cure increased (prostate tumor, seminoma, malignant melanomas, lung cancer, colon, stomach and esophagus), others not (glioblastoma, hepatoma ...) Dangerous also remain female cancers (breast, ovarian and cervical cancer ). Cancer treatment has three main components: - Surgical treatment - resection of the tumor (bearings). - Cytostatic therapy (chemotherapy and radiotherapy) - destroying tumor cells cytostatics or radiation. - Supportive therapy - aims to boost the immune system and regeneration of the body after chemotherapy. Cytostatic drugs used in chemotherapy are poisons that kill dividing cells. Addition to cancerous cells, unfortunately, even kill cells in growth areas of the skin, mucous membranes, gonads, hair roots, nail beds, and also the hematopoietic stem cell in bone marrow. This leads to a lack of white blood cells and severe damage to the immune system. Cytostatic treatment is a frightening experience in which patients suffer enormous fatigue, nausea, loss of appetite, loss of fertility and hair loss. The nails appear lines (Beauovy line). The patient's body accumulates minor wounds that can not heal. Recruited new and novel stem cell that is attempting to regenerate damage enter mitosis and subsequently destroyed. In this way the patient for a few months older physiologically for years. Similar side effects have also radiotherapy. The aim of this paper is to highlight the adaptogens which are suitable for supportive treatment of cancer. We find among them some gentle drugs that contribute to the destruction of cancer cells without burdening the patient toxicity. Adaptogens in the treatment of cancer Chemotherapy completely destroy both immunity and regenerative capacity of the affected organism. In this situation are welcome adaptogens that improve wound healing and regeneration . In cancer treatment adaptogens are four other important effects: - protect healthy cells from radiation and chemotherapy - Strong improvement of regeneration of the immune system - Immunomodulation direction cytotoxic response - direct anti-tumor effects Protecting healthy cells against radiation and chemotherapy Available natural adaptogens have the ability to slow down the cellular aging, protects the patient from radiation and prevent the apoptosis of healthy cells. Ginseng is, according to experts, the most effective means available against radiation damage whatsoever ( Yonezawa1976rri , Takeda1981rri , Yonezawa1981rri , Takeda1982rri , Yonezawa1985rri ). Adaptogens not only protects against radiation, but also against apoptosis of healthy cells from chemotherapy. Schisandra, eleutherocok, Leuzea Regeneration of the immune system xxx Schisandra, eleutherocok, Leuzea Immunomodulation direction cytotoxic response xxx Schisandra, eleutherocok, Leuzea Jana Merhautová in his lecture phytopharmakology addition immunostimulants such as oncology mentions unkárii matted (Uncaria tomentosa, Vilcacora, cat's claw), purple coneflower (Echinacea purpurea), catcher (Tabebuia impetiginosa), bee product and beer yeast. Direct tumor effects of adaptogens Yeah ... right ... ginseng Reishi mushroom shiny ... but also many other adaptogens Schisandra, eleutherocok, Leuzea In relation to the ability of adaptogens protect cells from damage by radiation and chemotherapy is appropriate to ask whether these drugs are not in the same way also protect cancer cells. According to most of the available publications do not. Adaptogens have specific according to available research, direct anticancer effects, the overall balance (ie. They behave like friendly cytostatics). Other anticancer sponges List of species is not closed, I made the choice at its own discretion. - According to the number of publications is clearly the most attractive for researchers adaptogen ginseng. Here it goes into effect when ginseng overshadows other adaptogens more than it should. Other adaptogens are compared with ginseng ineffective or inferior, just less rozšířené. Outkovka eater (Trametes versicolor) - Cordyceps (Cordyceps sinensis) - Inonotus obliquus (Inonotus obliquus), CagA - Ohňovec furrow (Phellinus linteus) - Choros Oris (Polyporus umbellatus) Group anticancer hub is not clear-cut, as well as common edible mushrooms are not specifically enhance anti-cancer immunity ( Patel2012rdm , Feeney2014mhs ). Specifically, it is e.g. Oyster mushroom (Pleurotus ostreatus) , shiitake (Lentinus edodes, Shiitake), Grifola frondosa (Grifola frondosa, maitake), spiky coral (Hericium erinaceus), but also ordinary button mushrooms (Agaricus bisporus, A. blazei), see Xu2012cpe , Martin2010ccs . Asian mushrooms (Shiitake, maitake), while no more effective than ours, bearer of nonspecific anti-cancer effects are in fact common fungal agents: B-glucan ( Temizoz2016vap ), ergosterol ( Li2015epf ) and fiber. Information that our Boletus, respectively. the parasite nedohub zlatovýtrusý carcinogenic is false . In assessing the anticancer mushrooms are worth avoiding extremes. Oncologist nor the patient from them should not wait for a miracle. When it comes to medical patients who have developed malignancies, it is clear that his immune system had its best chance missed. Moderate or even strong boost immunity not usually enough to cure. On the other hand, it is a misconception that anti-cancer mushrooms are ineffective and do not deserve his epithet. Such an opinion in the light of available scientific studies stand. Ginseng is an adaptogen front suitable for the treatment of cancer Consequently supportive role ginseng cytostatic therapy. There are dozens of publications pointing to its direct anticancer effects, which recently reviewed the Wang2016rgc . According to Dr. Lars Christensen ( christensen2009gcb ) can be documented anti-cancer effects of ginseng divided into three groups: cytostatic effect, reducing malignancies and limit the growth of blood vessels in tumors. According Takei2008dcp ginseng stimulates the immune system toward a cytotoxic response. Increases the activity of NK cells ( Yun1993iat , Jang2015pnk , Takeda2015ink ) and macrophages ( Wang2010ita ), hence its suitability in imunoléčbě cancer. According Wong2010age performed ginseng extract in a mouse model against lung cancer. Ginseng also performed against cells of human gastric carcinoma ( Hwang2015efg ), human gallbladder cancer ( Wu2015ers ) and human cells of acute lymphoblastic leukemia ( Xia2016iap ). Ginseng metabolite compound A acted against hepatoma cells ( Song2010imc ) ginsenoside F2 against glioblastoma rat model ( Shin2012aeg ) gssd. Rg 3 against the human myeloma cells ( Li2016imm ) and acidic polysaccharides ginseng improved results cytostatic treatment of melanoma in a mouse model ( Shin2004eae ). Gssd. Rg 3 and the compound to inhibit angiogenesis in tumors of the lung, stomach and ovaries ( Wang2015gmc ). The compound acts by inhibiting p38 MAP kinase ( Jeong2010cib ) and the regulation of sphingosine kinase-1 ( Shin2014gci ). Somewhat less inhibitory effect on angiogenesis is gssd. Rb 1 ( Papapetropoulos2007gor , Wang2015gmc ). Another panaxosidy (e.g. e.g. gssd. Rg 1 ), but have on the growth of blood vessels opposite effects ( Sengupta2004may ). According Kim2006esg ginseng improves the quality of life for cancer patients. Lingzhi mushroom is medicinal mushrooms with direct anticancer effects Lingzhi mushroom (Ganoderma Lucidum) contains a huge variety of triterpenoid saponins - ganoderové acid, ganoderenové acid, lucialdehydy, ganoderioly and more (see Paterson2006gtf ). A total of 315 triterpenoids in the genus Ganoderma describes overview Xia2014crs , which is more than 182 triterpenoids described in the genus Panax ( christensen2009gcb ). Reishi further comprises typically fungal B-glucans, polysaccharides and proteoglycans. As bearers of specific anti-cancer effects are considered triterpenoids and polysaccharides, to some extent also a substance (eg. Polypeptides). Lingzhi mushroom is completely harmless ( Wachtelgalor2004gll , Kwok2005prd ). Reishi promotes cytotoxic immune response ( Radwan2011air ). The extract and pure B-glucan (fukogalaktan) increases outpouring of IL-23 on dendritic cells and T cells induces differentiation of Th17 ( Yoshida2012pit ). Polysaccharides Reishi accelerate the proliferation of bone marrow macrophages and increase the production of IL-1B, IL-6, IL-12p35, IL-12p40, IL-18, TNF-a, IL-1B and IL-12 ( Ji2011ibm ). Ganoderma formosanum activates antitumor immune response in vivo in mice afflicted with cancer ( Wang2014aai ). Reishi is effective against cell lines of colon cancer in vitro ( Thyagarajan2010tfg , Jedinak2011glt , Hong2004egl ) and limits the malignancy of gastric cancer cells ( Jang2011aae ). Direct cytotoxic effects of specific triterpenoids Reishi comments Xia2014crs . According Min2000tfs ganoderové acid Y, δ, e, Z, n, and θ in vitro against cells sarcoma and lung cancer. Ganoderová acid. Jc inhibits the growth of leukemia cells (HL-60) and E ganoderiol growth of breast cancer cells (MCF-7). According Wang2010nga ganoderové acid Mf Mk S and destroys cell lung cancer (95-D) and cervix (HeLa) in concentrations 15-40uM. Ganoderová acid. E and lucidenové acid. N and A is effective against hepatoma cell lines and leukemia ( Wu2001cgl ) ganodermová acid Ja against hepatoma cells ( Li2005gal ). Lucialdehyd B and C ganodermanonol and ganodermanondiol act against cells of lung cancer, mammary cancer, and sarcoma ( Gao2002nta ) luciadiol and ganoderiol F against HeLa cells of cervical cancer ( Cheng2010ctf ), two more specific lanostanoidy against cells leukemia, cervical carcinoma, hepatoma and gastric cancer ( Guan2008clt ). According Ma2012ltf anticancer and ganoderové acids and C 1 and lucialdehydy D and E, all at concentrations of ~ 20ug / ml. Regarding the in vivo studies, G. lucidum cancer-operated mice transplanted with liver cancer ( Chen2010pgl ) and other tumors ( Trajkovic2009apg , Nonaka2006aaa ). G. lucidum was immunostimulatory in vivo and anti-radiation effect ( Gao2005aau , Pang2007pnp ) and prevent the formation and metastasis of lung cancer in mice exposed to carcinogens cyclophosphamide ( Nonaka2008eaf ). G. atrum worked cancer-mouse model ( Zhang2014pfg ). Ganoderová acid T reduces the malignancy of lung cancer cells in vivo ( Chen2010gai ). Regarding clinical trials, Gao2003egg tested the effect of Reishi polysaccharides on 30 patients with advanced cancer and found an increase in the number of CD56 + cells and NK cell activity. Chen2006mir found in 41 patients with advanced colorectal cancer treated with Reishi increase of CD3, CD4, CD8 and CD56 + lymphocytes. Sun2014pal again found improvement of immune parameters in patients with lung cancer using Reishi. I think an interesting clinical study Oka2010wef that in 96 patients (102 in the control group) found that Reishi used in the 12-month period prevents the development of colorectal adenomas, neoplasms of which may develop cancer of the colon and rectum. When taking Reishi are known cases of complete cure, Suprasert2014ccg reports on five such patients. Better clinical studies in principle exist, although current research and practical experience clearly shows that Reishi mushroom is friendly and cytostatic specific antitumor immunity stimulant. Scientists agree that doctors should this fungus had systematically ( Sliva2003glr , Radwan2011air , Cheng2015glc , Jin2016glr ). vvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvv This list is not fanciful. Behind each of these points stand now hundreds of scientific publications (some of which I quote below), although reports WHO and the EU will tell you that this research en Somme does not mean anything. Researchers are most attracted to true ginseng, perhaps overshadows other adaptogens more than it should. Adaptogens type of ginseng excel in treating cancer protective and regenerative effects. Immunomodulatory and direct anti-tumor effects are characterized adaptogens type lingzhi mushroom . In developed countries recognizing traditional medicine (Japan, Taiwan, today i PRC) is the administration of adaptogens routine part of treatment for cancer patients. For example, in Taiwan in the treatment of breast cancer using dozens of different herbal combinations, which is most common děhel Chinese and ginseng ( Lai2012ppc ). (In Taiwan, there is no animosity between scientific medicine and TCM.) Other adaptogens to prevention and supportive treatment of cancer This subchapter I would start by saying that reveal the denouement: Good adaptogenic Roštín cancer exist, but they can not determine what they are and that, paradoxically, precisely because of the fact that this effect of herbs pays too much attention. Although on a much adaptogenic plant anticancer publications, there is never certainty whether this plant has a strong and specific effects or only a weak and nonspecific. Of necessity, therefore I am resorting to suggest that ginseng and anticancer especially mushrooms, which have the effect I'm sure (see also study Yun1995tnm ). If someone wants to include treatment also adaptogens, then doing poorly due to an excess of options, I am unable to give any specific recommendations. It's a fact, that: - In cancer research is the result of irrational preoccupation overinvestment (he thinks it's even Terry Pratchett). - Mild, non-specific anti-cancer effects of a large number of plants and fungi. - Complete cure cancer adaptogen weak action is a hopeless undertaking. For an illustration, the database anticancer effects of herbs CancerHSP ( Tao2015cah ) contains more than 2,400 potentially anticancer plant, but the information contained therein do not give any guidance whatsoever to their comparisons. The situation is similar in terms of anti-cancer effects etnobotanická database, Dr. Duke and database TCM herbs TCMSP ( Ru2014tds ). According to points 1 and 2 also show that the anticancer effects of herbs often pay those scientists who are currently in need of rapid publication than those who are really trying to discover something new. Item 3. turn is due to the fact that unlike lifestyle diseases cancer during treatment evolutionarily and develops against drugs acquires resistance. Therefore, even if an adaptogen over several weeks or months to occupy the cancer usually eventually gets the upper hand. For all these reasons, I ascribe publications on anticancer effect of herbs less weight. With this introduction I offer them a partial list. - In the genus Panax are other species ( American ginseng , ginseng notoginseng , etc.) similar to the composition of active ingredients as P. ginseng and are analogous to their anticancer effects (see list Wang2015cap , Wang2016pap , Wang2008prg , He2012aap ). - Lycium barbarum polysaccharides (LBP) from fruits goji (Goji) promote the proliferation of spleen cells ( Peng2001sci , Gan2004iaa ) and T lymphocytes ( Chen2008atl , Gan2003ppc ) recovery of immunity after chemotherapy ( Gong2005tel ) and directly effective against tumor cells of the liver, prostate and breast cancer ( Chao2006hwe , Liu2000eia , Li2009lbi ). - Balsam apple bitter (bitter cucumber) has in addition to the effects against diabetes and obesity considerable preventive potential against cancer, which describes the reports Raina2016pbm Dandawate2016bmp and Nerurkar2010bma . - AT cicimku Date Fruit was found anticancer effects on the liver in vitro ( huang2007maa , huang2009czj ). - Hailing snodárná has an antitumor effect due to its inhibitory effect on the growth of vessels ( Mohan2004wip ). - AT Chinese děhele was detected anti-cancer effect in vitro and in vivo ( Cheng2004aea , Tsai2005aea , Kan2008sae etc.) Polysaccharides děhele danced against three cancer models in mice in vivo ( Shang2003esa ). Děhel however, it contains phytoestrogens, and its effect is unclear to me. Some of the substances contained děhele promote the proliferation of HER2 + breast cancer cells ( Chang2006mhe ), but despite the děhel Taiwan TCM herb most commonly prescribed breast cancer ( Lai2012ppc ). - Anthraquinones and polysaccharides from aloe (Aloe vera) act cancer-vitro ( Xu2016rse , Luo2014caw , Chen2016ent , Chihara2015eae , Hussain2015avi , Yonehara2015ave ) and in vivo ( Shimpo2014iel , Pan2013iag and others), a good overview of the anticancer properties of aloe is Harlev2012apa , anthraquinone aloe-emodin with pays overview Chen2014pae . In cancer it is of great importance to inspire the practice of TCM in a single country where the medical arts have survived without interruption - in Taiwan. Already mentioned study Lai2012ppc found the top 10 in TCM combination prescribed breast cancer in Taiwan and found that 7 of them contain děhel Chinese ginseng and 6. Other important herbs in these combinations are Vladimiria souliei, cardamomum Amomum, Pinellia ternata, Astragalus membranaceus, Forsythia and Jujube. Overview Radomskalesniewska2015apr focuses on products with activity against the growth of blood vessels in tumors, which assigns Rhodiola rosea , třapatce purple , Aloe (Aloe vera) and olověnci cejlonskému (Plumbago zeylanica). According to the survey Safarzadeh2014hmi of cancer-also ginger true crocus (Crocus sativus), curcumin and xanthorrhizol of turmeric , resveratrol, quercetin, genistein legumes, bajkalein of Šišák Baikal , řemdihák fuzzy (Uncaria tomentosa), Isatis tinctoria (Isatis tinctoria), pagoda tree yellowish (Sophora flavescens), catcher red (Tabebuia impetiginosa). Adaptogens versus standard treatment procedures in oncology The contradiction between them in fact exist. Pharmacology does not ask whether a drug is natural or synthetic, only whether and how it works. This contradiction is artificially created by monopolists who seek traditional patent medicines not subject to squeeze into the role of illegitimate and anti-scientific "alternatives". Natural toxins are actually in oncology using a large - many cytostatic drugs derived from medicinal plants that do not meet the definition of adaptogen. It is true that in the 20th century during the boom invasive medicine and pharmacotherapy Paracelsian emphasis was on adaptogens, but it is expected that the treatment of lifestyle diseases dominating the medicine of the 21st century will be natural and later synthetic adaptogens important place. For clinical use adaptogens it is crucial that these do not represent an additional burden for the metabolism and detoxification system of the patient. On the contrary, protect and reduce the toxicity of standard medical treatments. These substances are therefore possible without risk classified as an adjuvant at any stage cancer treatment. At least with Ginseng and Reishi mushroom is also not have to worry about drug interactions. Danger interactions adaptogens highly exaggerated manufacturers of conventional drugs. It's good to know the doctors can promote regeneration of cancer patients and other than diet no. 11 with the addition of vitamins and minerals. Other related articles: - Cancer of the rectum and colon cancer (colorectal carcinoma) - Breast cancer - Leukemia (blood cancer) - Lung cancer - stomach cancer - Liver cancer (hepatoma) - malignant melanoma xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx Other notes How do the antineoplastic agents: It is for example 5-fluorouracil, which inhibits the synthesis of thymidine. Thymidine is needed for DNA synthesis, and otherwise in the cell for anything else used. His lack kills only dividing cells, which begin with DNA replication, but due to lack of thymidine can not finish it and die. Some used cytostatics are natural (vinblastine, vincristine, taxanes etc.), others are synthetic. Their common feature is only that selectively kill only proliferating cells. Doctors are trying to side effects of chemotherapy and radiotherapy to alleviate targeted cytotoxic chemotherapy and radiation targeted radiotherapy and bone marrow autotransplantation. For natural anticancer drugs can mention effective, but downright poisonous natural cytostatics. These plants are adaptogens contradiction: while killing cancer cells but healthy body severely damaging. I mention it only for completeness, its independent use is prohibited. These include: trojkřídlec wilfordův (Tripterygium wilfordii), vinblastine and vincristine vinca minor (Vinca minor), taxol from yew (Taxus baccata), camptothecin from kamptoteky ostrolisté (Camptotheca acuminata), podophyllotoxin from noholistu štítnatého (Podophyllum peltatum), mistletoe lectin (Viscum album) and others. Reishi: - lucidumol C 26899240 - Reishi stimulates NK cell activity (23803412) - Reishi polysaccharides have immunostimulating and anti-radiation effect in vivo in a mouse cancer model (17995702). Cancer in general: - Astragali radix 25087616 - Atractylodes macrocephala, Lance 25066389 - TCM Cancer 24871650 - Alstonia scholaris and A. macrophylla 24486598 - Loranthus parasiticus 24467533 - apparently j Ed kryptolepin 24391229 - Ficus carica 24159359 - Bruce javanica 24066797 - famous Indian adaptogen Chlorophytum borivilianum 24045177 - plants in Cervical Cancer Therapy 23886123 - apparently cytotoxic traditional plants 27457235 - Bangladeshi medicial plants against Cancer 27382642 - lichen metabolites 26704132 - others TCM fulltext review 26622657 - Moringa oleifera 26428271 - curcumin (search better reference) - Croton crassifolius (sounds sarcastically) against the growth of blood vessels 26386379 - resveratrol (search better reference) - pornatka coconut (search better reference) - Momordica cochinchinensis 26225702 - Kalanchoe tubiflora 26179408 - kostunolid of Costus speciosus 26178525 - pancreatic cancer case report 26171011 - triptolid (search better reference) - chikusetsusaponin IVa 26151883 - Sophora in TCM 26087234 - Helicteres angustifolia 26087229 - novel cytotoxic steroidal glycosides from the roots of Liriope muscari 26073343 - betulin (search better reference) - Angelica (search better reference) - berberine (search better reference) - Pogostemon cablin 26042464 - 4-methylcoumarin 26017566 - Perilla frutescens 25996217 - Baliospermum montanum 25960237 - Ophiopogon japonicus 26826325 - myricetin 26455550 - Epimedium 26243581 - gingerol and shogaoly 26228533 - Trametes robiniophila 25955759 - Loranthus ferrugineus 25830054 - Portulaca oleracea 25692148
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Rak je vodeći uzrok smrti u civiliziranom svijetu. Zajednička značajka raka je da se stanovništvo vlastite stanice počinje višestruko nekontrolirano na štetu organizma. Ova proliferacija može nakon određenog broja generacija prestaje - onda je benigni tumor (dobroćudni), kao što su madeži, adenoma, polipoza kolona i malih tumora unutar tijela, čije postojanje ne shvaćaju. Nasuprot tome, raka stanice (maligni) tumori nikada ne prestaju podjele i često imaju sposobnost da metastaza - širenje u udaljenim dijelovima tijela. Raka u širem smislu odnosi se na bilo malignih tumora. U užem smislu, karcinom je maligni tumor koji proizlaze iz epitela kože ili sluznice - karcinoma. Manje česta sarkom je rak vezivnog tkiva. Zdrave stanice imaju mnoge prepreke protiv neograničenog podjele. To je kao kontakt inhibicije: Cell prestane dijeliti, oni prolaze nema prostora. Zatim tu je Hayflick granica: većina stanica ne može rasti cijelo vrijeme, ali je ograničen na nekoliko desetaka podjele. Najviše tijelo (somatskih) stanica ima sposobnost da trajno podijeliti OFF - su fazi diferencirane. Sposobnost da dijele svoje tijelo zadržava samo mali dio stanica - matične stanice. Oni se aktiviraju ozljede, ali u nekim tkivima su još uvijek aktivni. Rak su stoga skloni oni tkiva koje rastu u odrasloj dobi i regenerirati - koža, sluznica, mliječne žlijezde, gonade ... Odnosu somatske stanice su nediferencirane stanice raka. Oni podsjećaju matičnih stanica - ako su mladi, dijeljenjem i priprema za stvaranje korisne tkivo, ali da cilj nikada neće odrasti. Tumorske stanice su posebno na početku ponašaju gotovo normalno i držite još svoju izvornu funkciju. Zbog toga, na primjer, tumora hipofize, nadbubrežne žlijezde i drugih endokrinih poremećaja hormonskih doći jer su tumorske stanice još bavi izvornom zanimanja - proizvodnja hormona. Tumorske stanice su također posebno na početku ponašaju velike želje da se razlikovati, tj. Doista stvaraju tkiva za čije je stvaranje on vjeruje plinovoda. Često samo blagi kemijski podražaj na tumorske stanice odlučila rasti i postati funkcionalna, terminalno diferenciranim somatskih stanica ( Kawamata2006dts ). Tijekom raka kancerogene stanice njihove inhibicije i pristojan ponašanje postupno izgubiti. Uče se također izbjeći prepoznavanje od strane imunološkog sustava, apoptoza gube sposobnost i volju da se diferenciraju i postupno prilagoditi na citostatike koje liječnik pokušava izliječiti rak. Razvoj raka toliko je stohastički proces biološke evolucije odvija u populaciji stanica raka. Da bismo razumjeli fenomen maligne degeneracije je važno shvatiti da svaki rak: - Ona dolazi izvorno iz jedne stanice određenog tkiva. - Tijekom njegova razmnožavanje nastavlja stohastički evolucijski skok prema povećanom malignosti. - Prije ili kasnije to će se natjecati s imunosnog sustava domaćina. Od tih svojstava ukazuju na to i zašto je to tako teško za liječenje raka. stanice raka gotovo od samog početka, jer ne razlikuje od normalnih stanica i da je teško razmišljati o toksina koji bi selektivno ubiti, a nije štetan za cijelo tijelo istovremeno. Sposobnost stanica raka proći evoluciju pak znači da čak i ako je liječnik korištenjem metode tvari ili liječenja čuvati bolesti u uvali privremeno, stanice raka mogu razviti otpornost tijekom vremena i Dana Latka / metoda prestaje raditi. Recidivi dovoljno da pokušaju liječiti jedan preživio samo održive stanice raka. Također je vidljivo da ljudi rade u pogledu imuniteta protiv raka vrlo dobro. Čovjek je, naravno, dugovječna životinja i rak je opremljena bolje od većine kralježnjaka. Tijekom života našeg imunološkog sustava prepoznaje i uništava desetke tumora, bez da nas obavijestite. Dok miševi i štakori umiru od raka nakon samo jedne godine, psi i mačke dobiti rak i nakon 5 godina, ljudski imunološki sustav omogućuje nam relativno sigurno od raka preživi pet desetljeća aktivnog života. To je u našu korist, ali s druge strane, to također znači da kada je riječ o medicinskim pacijentima koji su razvili malignosti, pa je njegov imunološki sustav nije uspio u svojoj funkciji i njihovu najbolju priliku da se prijave imunitet protiv raka propustili. Rizik od raka povećava oštro u starosti, koja kod ljudi dolazi relativno oštro više od 6 desetljeća života. Osjetljivost na rak u starosti se povećava ne samo zato što nose oštećenja DNA akumulirane tijekom života, ali i zbog ukupnog pogoršanja u tijelu i imunitet. Stohastičke prirode maligne degeneracije i bolesti je razlog zašto rak pojavljuje samo u nekim ljudima i različitim pacijentima napreduje različitim brzinama. liječenje raka Iz razloga što je već spomenuto u prevenciji i liječenju raka je uvijek težak problem. Medicinski napredak u liječenju raka, unatoč troškova nastalih u istraživanju skroman. Za neke vrste raka blago povećava vjerojatnost lijek (tumora prostate, seminom, malignog melanoma, pluća, debelog crijeva , jednjaka, želuca i), ali ne i s drugim (glioblastom, hepatoma). Opasni ostaju ženske raka ( dojke , jajnika i rak vrata maternice). liječenje raka ima tri standardne komponente: - Kirurških obrada - odstranjivanja tumora ležajevi (ležajevi). - Citostatik terapija - uništavanje selektivni otrova staničnih ili zračenja. - Potporno liječenje - regeneracija tijela i ojačati imunološki sustav Osim toga, to se odnosi bioléčba (imunoléčba), hormonsku terapiju, liječenje indukcijom diferencijacije i sl, ali gore navedene tri modaliteta i dalje presudno. Adaptogens i gljive protiv raka, koji su istaknuti, pripadaju uglavnom podržavaju tretman, ali nema ih nedostatak ili izravno citostatik učinak. Dok konvencionalni kirurških i citostatik terapija djeluje destruktivno na tumor i tijela, regeneraciju podršku Adaptogens i obnavljanja oštećenih imunološki sustav. Antitumorski gljive imaju izravan antitumorski učinak kao stimulacijski učinak na citotoksične imuniteta i proapoptotska učinak na stanice raka. Istraživanje tih lijekova ponovno opsežna i ispod njega dati reference. citostatik liječenje stanice raka iz zdravih stanica je vrlo teško razlikovati. Uglavnom, jedini pouzdani Posebnost je da su stanice raka podijeliti na neodređeno vrijeme. A to utječe na njihovu vlasništvu liječenjem sa citostaticima. Citostatski učinak je uglavnom bilo posljedica koje štete ili ubija diobu stanica, ali je relativno bezopasan za mirnim, koje se dijele stanice. Ovaj objekt ima primjer zračenja. Ionizirajućem zračenju oštećuje najviše diobu stanica te stoga koristi zračenje za uništavanje tumora. Još specifični učinak na diobu stanica, ali uz kemijski citostatik - mitotičkih otrova koji se koriste u kemoterapiji. To je, na primjer 5-fluorouracil, koji inhibira sintezu timidina - jedan od građevnih blokova četiri DNA u stanici nema drugog korištenja. Mnogi citostatici upotrijebiti prirodnog porijekla vinka alkaloidi (vinblastin, vinkristin), taksane iz tise, podofilotoksin, kamptotecin, bakterijska streptomicina itd Nažalost, osim stanica raka u tijelu podijeljen brojnim drugim stanicama, a oni su oštećeni od strane liječenjem sa citostaticima, kao i tumor u cijelosti. Oni su epitelne stanice kože, sluznica, zone rasta korijena kose, noktiju kreveta i također hematopoetskih matičnih stanica, koje proizlaze iz crvene i bijele krvne stanice. Citostatik tretman je zastrašujuće iskustvo, u kojoj pacijenti pate ogroman umor, mučnina, gubitak apetita i gubitak plodnosti. Kosa ispadne i tu su linije na noktima (Beauovy linija). Jedan od najgorih posljedica teškog oštećenja imunološkog sustava uništavanjem bijelih krvnih stanica. Ciljana terapija raka Liječnici od samog početka terapije sa citostaticima pokušao to nekako ograničen na stanice raka. Na primjer, radioterapija namjerno ozračena s tumorom, a ostatak tijela dobiva relativno malu dozu. Za kemoterapije od 50-tih godina 20. stoljeća, provodi ciljano perfuziju zahvaćenih organa. No, ove metode ne uspiju za velike metastaza. U tim slučajevima, tu se sada zove. Biološka terapija (bioléčba) ispravno imunološka obrada. Rak Bioléčba nije ništa novo. Davno je bilo nastojanje za stvaranje cjepiva protiv raka. Glavni problem je u tome što pacijenta vlastiti imunološki sustav obično se teško oštetile terapije sa citostaticima. Trenutno, dakle imunoléčbě antitijela protiv stanica karcinoma, a proizvode se umjetno primjenjuje intravenski na pacijentu. To je dobra poslovna strategija, ali ne i čudesan način. Liječnik zapravo samo oponaša pacijenta imunološki sustav i time stoji pred izazovom, koja ima prirodni imunitet nakon što je pacijent nije uspjelo. Vrlo obećavajući je kombinacija protutijela na a-radioizotopa koji se zatim lokalno ozračivanja tumora mali žarišta (ciljana terapija alfa). Ciljane a terapija je posvećena primjeru br. 3. Tekući radiofarmaka rujna 2008. , od posebne publikacija npr Tolmachev2007rth (lutecij-177 HER2 protutijela protiv raka dojke ) i Liepe2009a2a (Alpharadin, radij 223 karcinom prostate). Istraživanje aktivnosti u ovom području napreduje intenzivno, za pregled vidi Gudkov2016trt . Podržavaju liječenje raka Zaštitna terapija nije lijek za rak sekundarne. Dok je u drugim bolestima može se rabiti prirodne regenerativne sposobnosti, citostatik liječenje imuniteta kod oboljelih i regenerativne sposobnosti temeljito uništen. U tijelu tijekom kemoterapije i novo zapošljavanje novih matičnih stanica koje se pokušavaju obnoviti i time su uništeni. Pacijent za nekoliko mjeseci fiziološki dobiva stariji godine. Kao što je dobro patiti imunološki sustav, u kojem je iz temelja uništio roditeljske stanice koštane srži. Adaptogens vrsta ginsenga štiti od zračenja i kemijskih oštećenja i pomoći u oporavku. Ti njihovi učinci su znanstveno dokumentirana, ali je prikladno pitati da li analogija neće zaštititi stanice raka. Prema stručnjacima, to nije - specifični adaptogens ne štite samo stanice raka, već naprotiv aktiviraju imunitet protiv raka i izravno uzrokuje apoptozu stanica raka. Izravno djelovanje protiv stanica karcinoma je značajan za antitumorski gljivica - gljivica adaptogens obilježen Lingzhi gljiva. Opet, pitanje je da li su znanstvenici istražuju adaptogena pate pristranosti prema svom predmetu. Ovo pitanje postoji i stalno se riješiti samo s adaptogena, ali iu svakoj grani znanosti. Čudesna lijek za rak postoji i to nije ni adaptogens. I oni možda postoje ograničenja koja sprečavaju znanstvenike izmisliti pouzdan lijek za rak. Ginseng adaptogen izvanredno prikladni rak Istraživanja ginseng za liječenje raka se od četiri vrste učinaka: (1) sprječavanje i (2) za zaštitu i za jačanje tijekom ozračivanja i kemoterapijom, (3), imunomodulatora i (4), koji izravni antitumorska dalje podijeliti u tri potkategorije. 1. preventivno djelovanje: Sa stanovišta sprečavanja uporabu ginsenga negativno koreliraju s incidencijom raka ( Shin2000cpp ) preventivni učinak protiv raka može se pripisati određenoj panaxosidům ( Shibata2001ccp , Wang2008icp , Choi2013bbc ). Kliničke studije koje potvrđuju ovu pojavu je Yun2010npe . Čimbenici koji smanjuju rizik od raka mogu uključivati protuupalni učinak ginsenga ( Hofseth2007ict ). Zaštitne i regenerativne učinke na rak u potpunosti su primjenjivi adaptogeni učinak ginsenga protiv oštećenja izazvanih zračenjem . Ginseng tijekom ozračivanja štiti stanice potiče regeneraciju tkiva i uglavnom imunološki sustav ( Yonezawa1976rri , Takeda1981rri , Yonezawa1981rri , Takeda1982rri , Yonezawa1985rri ). Prema kliničkim studijama, ginseng poboljšava kvalitetu života pacijenata oboljelih od raka i smanjuje nuspojave kemoterapije ( Kim2006esg , Yennurajalingam2015hag ). Treće Imunomodulacijski učinci: Prema Takei2008dcp ima ginseng imunomodulatorne učinke koji se pojavljuju prema citotoksične reakcije. Povećava aktivnost NK stanica ( Yun1993iat , Jang2015pnk , Takeda2015ink ) i makrofaga ( Wang2010ita ) i time doprinosi otpornosti protiv raka. Izravni antitumorski efekti su otkrivene U panaxosidů direktan učinak protiv tumora Dr. Lars Christensen podijeljeni u tri skupine: (1) citostatik učinak, (2) smanjenje malignosti, i (3) ograničavaju rast krvnih žila u tumorima ( christensen2009gcb ). Nedavni izvještaji antitumorsko djelovanje ginsenga su Wong2015rag i Wang2016rgc . Citostatski učinak je istraživan je in vitro na staničnim linijama i in vivo na životinjama. Brojne studije ne mogu citirati sve, biram nasumce: Prema Wong2010age izvodi ekstrakta ginsenga u mišjem modelu protiv raka pluća. Ginseng također izvodi na ljudskim stanicama karcinoma želuca ( Hwang2015efg ), humani raka žučnog mjehura ( Wu2015ers ) i ljudskih stanica, akutna limfoblastična leukemija ( Xia2016iap ). Ginseng metabolita spoj A , protiv stanica hepatoma ( Song2010imc ) ginsenoside F2 prema modelu štakora (glioblastom Shin2012aeg ) gssd. Rg 3 protiv ljudskih stanica mijeloma ( Li2016imm ) i kisele polisaharide ginseng poboljšanih rezultata terapije sa citostaticima u mišjem modelu melanoma ( Shin2004eae ). Gssd. Rg 3 i spoj koji inhibira angiogenezu kod raka pluća, želuca, jajnika i ( Wang2015gmc ). Spoj djeluje inhibiranjem p38 MAP kinazu ( Jeong2010cib ) i kontrolu sfingozin kinazu 1 ( Shin2014gci ). Nešto manje inhibicijski učinak na angiogenezu je gssd. Rb 1 ( Papapetropoulos2007gor , Wang2015gmc ). Još panaxosidy (npr npr gssd, Rg 1 ), a oba imaju suprotne učinke na rast krvnih ( Sengupta2004may ). Iako adaptogens promovira kao znanstvenik moram priznati da unatoč svim istraživanjima korisnosti ili nezamjenjiv raka ginseng nije znanstveno dokazano. To još nije ovdje pitanje da li je biljni tretman raka da ili ne - nakon svega, priznati citostatika mnogo slučajeva otrovi biljnog podrijetla (vinblastina, taksola, podofilotoksina itd, vidi prethodni odjeljak). Pitanje je, naprotiv, u mjeri u kojoj je model Adaptogens kao ginseng i aloe njegova popularnost zasjenila manje poznatih adaptogena prikladno rak. Dakle: Iako sam spomenuo puno znanstvenih resursa, pozivam vas pokušao ginseng, a ne za znanstvenih razloga, ali za neke druge, poput poštivanja neznanstvene TCM . U razvijenim zemljama koriste TCM (obično Tajvan) Ginseng je jedan od glavnih sastojaka smjese recept u TCM klinikama za pacijente s rakom ( Lai2012ppc ). Lingzhi gljiva je „čudo” gljiva protiv raka Naslov očito nije mislio ozbiljno. Reishi sjaj je Adaptogen sadrži veliku količinu od 100% nezázračných triterpenoid saponina - ganoderové kiselina ganoderenové kiselina lucialdehydy, ganoderioly i više (vidi Paterson2006gtf ). Ukupno 315 triterpenoidi roda Ganoderme pregled opisuje Xia2014crs , što je više od 182 triterpenoidi opisane u rodu panax ( christensen2009gcb ). Reishi gljiva obično dalje sadrži beta-glukana, polisaharide i proteoglikane. Pod antikancerogenih učinaka nositelja još Reishi polisaharidi i druge tvari (na primjer, polipeptida). Lingzhi gljiva nema nuspojava ( Wachtelgalor2004gll , Kwok2005prd ). Reishi podržava citotoksični imunološki odgovor ( Radwan2011air ). Ekstrakt i čisti B-glukan (fukogalaktan) povećava IL-23 izlijevanje dendritične stanice i T-stanice inducira diferencijaciju Th17 ( Yoshida2012pit ). Polisaharidi Reishi ubrzavaju proliferaciju makrofaga koštane srži i povećava proizvodnju IL-1, IL-6, IL-12p35, IL-12p40, IL-18, TNF-a, IL-1B i IL-12 ( Ji2011ibm ). Ganoderma formosanum aktivira antitumorsko imuni odgovor in vivo u miševa s rakom ( Wang2014aai ). Reishi je učinkovit protiv staničnih linija za karcinom debelog crijeva u uvjetima in vitro ( Thyagarajan2010tfg , Jedinak2011glt , Hong2004egl ) i ograničava malignosti želučanih stanica raka ( Jang2011aae ). Izravni citotoksični učinci Reishi triterpenoidi gljiva specifična komentari Xia2014crs . Prema Min2000tfs ganoderové kiselina, Y, δ, e, Z, n, θ i in vitro protiv stanica sarkoma i raka pluća. Ganoderová kiselina, Jc inhibira rast stanica leukemije (HL-60) i porast E ganoderiol stanica karcinoma dojke (MCF-7). Prema Wang2010nga ganoderové kiselina Mf MC i S uništava stanice raka pluća (95-D) i cerviksa (HeLa) u koncentracijama 15-40 um. Ganoderová kiselina, E lucidenové kiselina, N i učinkovit je protiv stanične linije leukemije i hepatoma ( Wu2001cgl ) ganodermová kiselina ja od hepatoma stanica ( Li2005gal ). Lucialdehyd B i C i ganodermanonol ganodermanondiol protiv stanica raka pluća, dojke i rak sarkoma ( Gao2002nta ) luciadiol i ganoderiol F na HeLa stanicama raka grlića maternice ( Cheng2010ctf ), dva određenije lanostanoidy protiv stanica leukemije, karcinom grlića maternice, hepatoma i karcinom želuca ( Guan2008clt ). Prema Ma2012ltf antitumorska i ganoderové kiseline i C1 lucialdehydy D i E, a sve u koncentracijama ~ 20 ug / ml. G. lucidum raka djelovao in vivo u miševa transplantiranih s rakom jetre ( Chen2010pgl ) i drugih oblika raka ( Trajkovic2009apg , Nonaka2006aaa ). G. lucidum je imunostimulatorni in vivo i učinak protiv zračenja ( Gao2005aau , Pang2007pnp ) i spriječi formiranje i metastaziranja raka pluća miševa koji su izloženi u karcinogenom ciklofosfamid ( Nonaka2008eaf ). G. atrum radio modela raka miša ( Zhang2014pfg ). Ganoderová kiselina T smanjuje maligna stanica raka pluća (in vivo Chen2010gai ). Što se tiče kliničkih ispitivanja, Gao2003egg testirali učinak Reishi polisaharida na 30 bolesnika s uznapredovalim rakom i otkrili povećanje broja CD56 + stanica i aktivnost NK stanica. Chen2006mir se u 41 pacijenata s naprednim rakom debelog crijeva tretirani s povećanjem Reishi CD3, CD4, CD8 i CD56 + limfocita. Sun2014pal opet vidio napredak u imunoloških parametara u bolesnika s rakom pluća tretirana sa reishi. Studije Oka2010wef 96 bolesnika (kontrola + 102) utvrdio da Reishi koristite starije od 12 mjeseci sprečava razvoj adenoma kolona, od kojih su neoplazme može razviti rak debelog crijeva i rektuma . Kada uzimanje reishi su poznati slučajevi potpunog oporavka, Suprasert2014ccg izvješća o tih 5 pacijenata. Čak i više nego ginseng s reishi je istina da bez obzira na broj entuzijasta znanstvenika preporučuju ovu gljivu na pažnju liječnika ( Sliva2003glr , Radwan2011air , Cheng2015glc , Jin2016glr ), financiranje kliničkih ispitivanja za nju nije impresioniran, pa je misao vodilja opet ostaje šarlatan TCM za što je reishi (ling-chi) čaroban lijek i kulturni simbol. Drugo antikancerogeno gljive U procjeni antikancerogeno hub je poželjno da se izbjegne krajnosti. Onkolog, niti pacijent od njih ne bi trebao čekati čudo. Kada je u pitanju liječnik s pacijentom razvio malignosti, jasno je da je njegov imunološki sustav je propustio svoju najbolju šansu. Umjereno, čak i jaki poticaj imunitet obično nije dovoljno da se izliječi. S druge strane, zabluda da gljive protiv raka nedjelotvorni i njegov epitet zaslužuju. Takvo mišljenje u svjetlu raspoloživih znanstvenih studija ne stand up ( Popovic2013mcu ). Popis vrsta koje se spominje nije potpun ili zatvoren: - Trametes versicolor - versicolor kamfor - cordyceps - Inonotus obliquus - CagA (pregled svojih anti-raka učinaka Song2013pua ) - Ohňovec plug - Choros Oris antitumorski gljive skupina nije jasna, kao i konvencionalni jestivih gljiva specifično povećavaju antitumorski imunitet ( Patel2012rdm , Feeney2014mhs ). Naime, na primjer kamenice , shiitake (Lentinula edodes. Shiitake), zec gljiva (zec gljiva, maitake), šiljat koralja (Hericium erinaceus), ali i obični šampinjona (Agaricus bisporus, A. blazei), vidi Xu2012cpe , Martin2010ccs . Azijski gljivice (Shiitake, maitake) nisu učinkoviti od našeg, nespecifično nosač antikancerogenih učinaka u stvari zajedničke gljivičnih sredstava: P-glukana ( Temizoz2016vap ), ergosterolni ( Li2015epf ) i vlakana. Informacije koje naše vrganj, respektivno. parazit nedohub zlatovýtrusý kancerogene je lažna . Ostali adaptogens podržati prevenciju i liječenje raka Rak je popularna tema u znanosti. Paradoksalno, zbog prevelike popularnosti predmeta teško je zapravo odrediti učinkovite antikancerogena adaptogena. Za ilustraciju, u antikancerogenih učinaka bilja CancerHSP ( Tao2015cah ) sadrži više od 2.400 potencijalnih antikancerogene biljke, ethnobotanical baze podataka, dr vojvoda i baza podataka TCM bilja TCMSP ( Ru2014tds ) dodati stotine bilja, ali nije jasno koji od njih djeluju snažno i da samo malo. Slabe i nespecifičnim učinke protiv raka u stvari sa začinskim biljem i gljivama vrlo česte, nego ispuniti nade pacijentima raka, na žalost, nije dovoljno. Određene antitumorski efekti su pronađeni u gotovo sve popularne adaptogena, od kojih svi nude više ili manje slučajan izbor: - U roda Panax vrste imaju ginseng američki , ginseng notoginseng sl sl sastav analogne P. ginseng i antikancerogena svojstva (vidi popis Wang2015cap , Wang2016pap , Wang2008prg , He2012aap ). - Kustovnica polisaharidi (LBP) od voća goji (Goji) potiče proliferaciju stanica slezene ( Peng2001sci , Gan2004iaa ) i T limfociti ( Chen2008atl , Gan2003ppc ) rekuperacija imunosti nakon tretmana (citostatik Gong2005tel ) i direktno na stanice raka jetre , prostate dojke ( Chao2006hwe , Liu2000eia , Li2009lbi ). - Balsam apple gorka (gorko krastavac) ima pored poznatog potencijala protiv dijabetesa i pretilosti preventivno potencijal protiv raka, vidi izvješća Raina2016pbm , Dandawate2016bmp i Nerurkar2010bma . - Postoje stotine studija koje pokušavaju znanstveno objasniti iskustva sa TCM Sisak bajkalským . Spomenuti samo za ilustraciju: Na primjer bajkalin izaziva apoptozu stanica raka jetre ( Yu2016bps ), prostate ( Chan2000iap ) i drugih oblika raka ( Luo2014sbe ). Slično vogonin djeluje nekoliko mehanizama uzrokuje stanične apoptoze, inhibira rast krvnih žila u tumorima i ima sinergistički učinak s citostaticima fluorouracila ( Wu2016awe ). U Tajvanski TCM često propisane posebno raka također kapica bradatog ( Lai2012ppc , Yeh2014hdc , Chao2014ppc ). - Za Cicimku datulja pronađen na jetru antitumorski učinak in vitro ( huang2007maa , huang2009czj ). - Dovikom snodárná dokumentirala antitumorsko djelovanje ( Dar2015pow ), na primjer, s obzirom na njihov inhibitorni učinak na rast krvnih žila ( Mohan2004wip ). - Kineski (Angelica kineskog) imaju antikarcinomsku aktivnost in vitro i in vivo ( Cheng2004aea , Tsai2005aea , Kan2008sae itd) polisaharidi plesali protiv tri modela raka kod miševa in vivo ( Shang2003esa ). Divlji Angelica kineski na Tajvanu TCM biljka najčešće propisane od raka dojke ( Lai2012ppc ), ali znanstveno je nejasno učinak ( Chang2006mhe ). - Antitumorski efekti bosiljak sveta raspravlja pregled Baliga2013osh . - Antrakinoni i polisaharidi iz Aloe vera raka-nitro čin ( Xu2016rse , Luo2014caw , Chen2016ent , Chihara2015eae , Hussain2015avi , Yonehara2015ave ) i in vivo ( Shimpo2014iel , Pan2013iag i drugi), dobar pregled protiv raka svojstva Aloe je Harlev2012apa , antrakinona Aloe-emodin je posvećen pregled Chen2014pae , Prema Lai2012ppc TCM praksa u Tajvanu osim Ginseng i Wild Angelica se često koristi Vladimiria souliei biljka, kardamom , pinelii tri lista , milkvetch Membranozni , plačući forzicija (forzicija suspensa) i žižule . Prema izvješću Radomskalesniewska2015apr ima učinak protiv rasta krvnih žila u tumorima Rhodiola rosea , ljubičasta Coneflower , aloe vera i Leadwort Lanke (grafit zeylanica). Rhodiola također naglašava Bocharova1994tpe . Prema izvješću Safarzadeh2014hmi ima limfna đumbir pravu , šafran , kurkuma i xanthorrhizol od kurkumovníku , resveratrol, kvercetin i genistein iz mahunarki, bajkalein i drugih flavonoida iz Siska Baikal , Uncaria tomentosa , Isatis tinctoria (Isatis tinctoria), pagoda stablo žućkaste (Sophora flavescens) i trans crveni (Tabebuia impetiginosa). Otrovni prirodni citostatici Za razliku od prirodnih Adaptogens mitoze, otrovi nekih otrovnih biljaka. Oboje ubiti rak kao i bilo koje druge dijeljenjem stanica i u liječenju raka obično koriste. To nije adaptogens, jer zdravo tijelo jako štetan. Ja to spominjem samo za potpunost, oni su svi vrlo opasni otrovi. Među najčešće koriste su vinblastin i vinkristin Vinca minor (Vinca minor), taksol (paklitaksel) sa tise (Taxus baccata) -kamptotecina u kamptoteky ostrolisté (Camptotheca acuminata), podofilotoksin (iz noholistu štítnatého Podophyllum peltatum). U ovoj kategoriji su vjerojatno vrlo obećavajući, otrovna trojkřídlec wilfordův (Tripterygium wilfordii), malo otrovne imela (Viscum album) sa svojim proteoglikana (lektini) i drugih biljaka. Nedavno je također izvijestio da je australska voćka iz obiteljskih Hylandia dockrillii pryšcovitých imaju jake cito učinke (vidi, ovdje ). Ne znam, međutim, ako Hylandia adaptogen i njezin utjecaj jamčiti ... Određene vrste raka, koje ću posvetiti više - Leukemije (rak krvi) - rak pluća - raka želuca - maligni melanom