http___magazin.net.hr_zdravlje_istrazivanja_muskarci-koji-bolje-spavaju-imaju-manji-rizik-od-agresivnog-raka-prostate_1.xml
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Melatonin linked to lower prostate CA risk When to Screen for Prostate Cancer Melatonin linked to lower prostate CA risk HealthDay News -- Men with higher levels of melatonin may have a lower risk of developing prostate cancer, according to researchers at the American Association for Cancer Research's Conference on Advances in Prostate Cancer Research. Risk for advanced prostate cancer was 75% lower in men with levels of 6-sulfatoxymelatonin -- a measure of melatonin breakdown in urine -- that were higher than the median value, Sarah C. Markt, MPH, from the Harvard School of Public Health in Boston, and colleagues reported. They examined the association between urinary 6-sulfatoxymelatonin concentrations, sleep patterns and prostate cancer risk in 928 Icelandic men from the from the AGES-Reykjavik cohort from 2002 to 2009. Overall, 111 men were newly diagnosed with prostate cancer, including 24 with advanced disease. The median concentration of 6-sulfatoxymelatonin was 17.14 nanograms per milliliter. One in seven men reported problems falling asleep, one in five men reported problems staying asleep, and almost one in three reported taking sleeping medications. Levels of 6-sulfatoxymelatonin were significantly lower in men who reported sleep problems at baseline, the researchers found. Higher urinary 6-sulfatoxymelatonin levels were associated with a decreased risk of prostate cancer, particularly advanced disease. After adjusting for potential confounders, men with high levels of 6-sulfatoxymelatonin had a significantly lower prostate cancer risk (hazard ratio, 0.25). “Our results require replication, but support the public health implication of the importance of maintaining a stable light-dark and sleep-wake cycle,” Markt said. “Because melatonin levels are potentially modifiable, further studies of melatonin and prostate cancer risk and progression are warranted.” References - Markt S. Abstract # A21, PR04. Urinary melatonin levels, sleep disruption, and risk of prostate cancer. Presented at: AACR Conference on Advances in Prostate Cancer Research. Jan. 18 to 21; San Diego, Calif.
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Za čak 75 posto!Kako muškarci mogu znatno smanjiti rizik od agresivnog raka prostate Spavanje će muškarce zaštititi od raka prostate, tvrde znanstvenici. Studija je pokazala da oni s visokim razinama hormona melatonina imaju 75 posto manje šanse razviti agresivniji oblik smrtonosne bolesti. Osobe s manjim razinama melatonina teže utonu u san i češće se bude tijekom noći. Znanstvenici su testirali razine melatonina kod 928 osoba tijekom sedam godina. U tom vremenu, kod njih 111 dijagnosticiran je rak prostate, a 24 ih je imalo uznapredovali oblik raka, koji je vrlo agresivan i najčešće smrtonosan. Pokazalo se da su oni s višim razinama melatonina imali 75 posto manje šanse razviti uznapredovali oblik raka, u odnosu na one s razinama nižim od srednjih vrijednosti. Voditeljica studije Sarah Markt, s Harvardske škole za javno zdravstvo iz Bostona, kaže: 'Nedostatak sna i drugi faktori mogu utjecati na smanjeno izlučivanje melatonina ili ga potpuno blokirati. Zdravstveni problemi povezani s melatoninom osim poremećaja sna uključuju i rizik od razvoja raka.' 'Naši rezultati govore o važnosti održavanja stabilnosti ciklusa svjetlo-tama te spavanja i buđenja.' Britanski liječnik dr. Matthew Hobbs upozorava da se u Velikoj Britaniji rak prostate godišnje dijagnosticira kod više od 40.000 muškaraca. 'Ključno je moći odrediti koji od tih muškaraca imaju veći rizik za razvoj agresivnog raka koji se širi na ostale dijelove tijela' Druga studija provedena na 572 osobe oboljele od raka prostate pokazala je da su oni koji su prije dijagnoze hodali brže imali bolje prognoze za liječenje. U tumorima su imali više krvnih žila i bile su veće, a američki znanstvenici kažu da to olakšava liječenje. Poznato je da fizički aktivni muškarci s rakom prostate imaju niži rizik od recidiva i smrtnog ishoda, ali do sada znanstvenici nisu mogli objasniti zašto. web preporuke sensaklub.hrKako laže koji horoskopski znak?