http___medlib.mef.hr_968__1.xml
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Marčinko, Darko and Marčinko, Vesna and Karlović, Dalibor and Marčinko, Anita and Martinac, Marko and Begić, Dražen and Jakovljević, Miro (2008) Serum lipid levels and suicidality among male patients with schizoaffective disorder. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 32 (1). Abstract Suicidal behavior in schizoaffective disorder is a serious problem and suicide risk during lifetime ranges between 5%–10%. Neurobiology of suicidal behavior has not been studied sufficiently, and a high number of studies are oriented toward lipid investigation. The aim of our study was to investigate whether there were differences in the level of lipids (cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides) in hospitalized suicidal (n = 20) and non-suicidal (n = 20) patients with schizoaffective disorder. The study also included male healthy control subjects (n = 20). Hamilton Depression Rating Scale (HDRS-17), and Positive and Negative Syndrome Scale (PANSS) were used to confirm the level of psychopathology in patients with schizoaffective disorder. Severity of suicidality was measured by Scale for Suicide Ideation (SSI) at time of admission. Results of the study indicated significantly lower concentrations of cholesterol (p   0.05). Duration of the illness was significantly (p < 0.05) shorter in suicidal patients. Suicidal patients also had a significantly higher score on HDRS-17 (p < 0.001) and PANSS (p < 0.01) compared to non-suicidal patients. Actions (login required) Downloads Downloads per month over past year
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Marčinko, Darko and Bilić, Vedran and Pivac, Nela and Tentor, Berislav and Franić, Tomislav and Lončar, Mladen and Medjedović Marčinko, Vesna and Jakovljević, Miro (2011) Serum cholesterol concentration and structured individual psychoanalytic psychotherapy in suicidal and non-suicidal male patients suffering from borderline personality disorder. Collegium Antropologicum, 35 (Suppl.). pp. 219-23. Croatian abstract KONCENTRACIJA KOLESTEROLA I STRUKTURIRANA INDIVIDUALNA PSIHOANALITIČKA PSIHOTERAPIJA KOD SUICIDALNIH I NESUICIDALNIH MUŠKIH BOLESNIKA OBOLJELIH OD GRANIČNOG POREMEĆAJA OSOBNOSTI ----- Rezultati istraživanja brojnih studija upućuju na povezanost niske razine kolesterola i suicidalnog ponašanja kod bolesnika iz različitih dijagnostičkih kategorija. Cilj ovog istraživanja bio je ustanoviti jesu li vrijednosti serumskog kolesterola kod suicidalnih muških bolesnika s graničnim poremećajem osobnosti (N=20) niže u odnosu na nesuicidalne muške bolesnike s graničnim poremećajem osobnosti (N=20) i kontrolnu skupinu zdravih muških ispitanika (N=20) i provjeriti utječe li strukturirana individualna psihoanalitička psihoterapija na suicidalno ponašanje. Skupine su bile usklađene s obzirom na dob i indeks tjelesne mase (BMI). Rezultati istraživanja pokazuju da nema značajnih razlika u vrijednosti serumskog kolesterola između suicidalnih i nesuicidalnih muških bolesnika s graničnim poremećajem osobnosti i kontrolnih zdravih muških ispitanika. Razina psihopatologije (mjerena skalama Brief Psychiatric Rating Scale i Hamilton Depression Rating Scale) bila je značajno naglašenija kod suicidalnih bolesnika u odnosu na nesuicidalne bolesnike, što upućuje da je u praksi bitno prepoznati određene kliničke simptome kod bolesnika s graničnim poremećajem osobnosti s ciljem da se prevenira suicidalno ponašanje. Nesuicidalni bolesnici značajno su češće primili strukturiranu individualnu psihoanalitičku psihoterapiju prije hospitalizacije nego suicidalni bolesnici. Ti rezultati naglašavaju ulogu ovog oblika psihoterapije u preveniranju suicidalnog ponašanja u bolesnika sa graničnim poremećajem osobnosti. English abstract Findings from numerous studies suggest an association between low cholesterol levels and suicidal behavior in patients with different psychiatric diagnoses. The aims of this case-control study were to test whether cholesterol levels in male suicidal patients (N=20) with borderline personality disorder (BPD) are lower than in male non-suicidal patients (N=20) with BPD and male healthy control group (N=20), and to evaluate the influence of structured individual psychoanalytic psychotherapy on suicidal behavior. The groups were matched for age and body mass index (BMI). Results showed that serum cholesterol levels did not differ significantly between suicidal and non-suicidal BPD patients and healthy controls. The level of psychopathology (measured by Brief Psychiatric Rating Scale and Hamilton Depression Rating Scale) was significantly higher in the group of suicidal patients, which indicates the importance of evaluating particular clinical symptoms in BPD, in order to prevent suicidal behavior. Non-suicidal male patients suffering from BPD received more frequently structured individual psychoanalytic psychotherapy prior to the hospitalization than suicidal group. These results emphasized the role of this type of psychotherapy in preventing suicidal behavior in BPD patients. Actions (login required)