http___livro-ensino-medio.f1cf.com.br_biologia_hr_biology-221.html_1.xml
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Many diseases can be depleted with the use of vaccine Source: Figure courtesy Drugstore Catarina, www.drogariascatarinense.com.br The gene vaccine or DNA vaccine, still under experiment and standardization, can become the greatest promise for combating infectious diseases for which today there is no effective prevention, such as herpes, AIDS, malaria, tuberculosis , hepatitis, schistosomiasis, dengue fever, among others. For the production of the vaccine gene, scientists remove the causative agent of the disease, which can be a virus, bacterium, fungus or parasite, a piece of the DNA molecule, which is its genetic code. When the inoculated animals or humans, this piece of DNA which encodes an immunogenic protein or a virulence factor, it has the capability of inducing the immune system to produce antibodies or stimulating cell mediated immunity, particularly cytotoxic or helper T lymphocytes ( a major defense cells in our body), protecting against infection by the pathogen from which the DNA originated. The method is considered more effective and safer than conventional vaccines certain that inoculate viruses or attenuated live bacteria and the person to force the immune system to produce antibodies or cell mediated immunity. These vaccines an attenuated live, although they work well, offer a degree of risk that the person to finish contaminated by the disease that is to be prevented. With the DNA vaccine does not. Currently, the isolation of genes or DNA is a technique mastered by science due to the great development of molecular biology in recent years. The genes are frequently related to the virulence or pathogenesis of infectious agents are linked to other DNA fragments, called plasmids, by genetic engineering techniques. This recombinant plasmid carries the message of the vaccine as if it were a CD containing a computer file: when applied to animals, cells of the immune system to recognize that message transmitted by plasmid like a computer reading CD, triggering the activation of the response immune. DNA vaccines, in addition to the specific cellular and humoral immunity, offer additional advantages compared to classical vaccines: "The vaccination as a public health measure, requires the induction of long-lasting immunity. Most vaccines used in childhood vaccination programs requires administration of successive booster doses with periodic revaccination. gene vaccine With this problem would be solved one Implications of Advances in Biological Phenomenon LIFE
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Mnoge bolesti mogu biti potrošen uz korištenje cjepiva Izvor: Slika ljubaznošću ljekarna Catarina, www.drogariascatarinense.com.br (...) Gena cjepivo ili DNK cjepiva, još u eksperimentu i standardizacije, može postati najveći obećanje za suzbijanje zaraznih bolesti, za koje danas ne postoji djelotvorna prevencija, kao što su herpes, AIDS-a, malarije, tuberkuloze , hepatitis, schistosomiasis, denga groznicu, među ostalima. Za proizvodnju cjepiva gena, znanstvenici ukloniti uzročnika bolesti, što može biti virus, bakterija, gljivica i parazita, dio DNA molekule, što je njegov genetski kod. Kad bakteriziranoj životinja ili ljudi, ovaj komad DNA koji kodira imunogenog proteina ili virulencije faktor, on ima sposobnost izazivanja imunološkog sustava da proizvodi antitijela ili poticajno stanica posredovani imunitet, osobito citotoksični ili pomoćne T limfociti ( jedan od glavnih obrambenih stanica u našem tijelu), štiti od infekcija patogena iz koje potječe DNK. Metoda se smatra učinkovitiji i sigurniji od konvencionalnih cjepiva određenim nasaditi da virusi ili razrijeđenim žive bakterije i osoba natjerati imunološki sustav da proizvodi antitijela ili stanica posredovani imunitet. Ova cjepiva atenuirani live, iako oni rade dobro, nude stupanj rizika da osoba ne završi zagađena bolest koja se može spriječiti. S DNA cjepivo ne. Trenutno, izoliranje gena ili DNA je tehnika savladati znanosti zbog velikog razvoja molekularne biologije u posljednjih nekoliko godina. Geni se često odnose na otrovnost ili patogenetskoj uzročnika su povezane s drugim DNA fragmenata, nazivaju plazmida, po genetičkog inženjeringa. Ovo rekombinantnog plazmida nosi poruku o cjepivu kao da je CD koji sadrži računalni datoteku: kada se primjenjuju na životinjama, stanice imunološkog sustava da prepozna tu poruku prenose strane plazmida kao CD računalnog čitanja, što je izazvalo aktiviranje odgovora imuni. DNK cjepiva, osim u određenim stanični i humoralni imunitet, nudi dodatne prednosti u odnosu na klasične cjepiva: "Cijepljenje kao javnozdravstvena mjera, zahtijeva indukciju dugotrajan imunitet Većina cjepiva koji se koriste u djetinjstvu programe cijepljenja zahtjeva. Administracija uzastopnih doze s povremenim ponovnog cijepljenja. gena Cjepivo S ovim problemom bi se riješio jedan Implikacije Napredak u biološkoj fenomen ŽIVOTA