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Overview Celiac disease (gluten-sensitive enteropathy), sometimes called sprue or coeliac, is an immune reaction to eating gluten, a protein found in wheat, barley and rye. If you have celiac disease, eating gluten triggers an immune response in your small intestine. Over time, this reaction damages your small intestine's lining and prevents absorption of some nutrients (malabsorption). The intestinal damage often causes diarrhea, fatigue, weight loss, bloating and anemia, and can lead to serious complications. In children, malabsorption can affect growth and development, in addition to the symptoms seen in adults. There's no cure for celiac disease — but for most people, following a strict gluten-free diet can help manage symptoms and promote intestinal healing. Next Symptoms The signs and symptoms of celiac disease can vary greatly and are different in children and adults. The most common signs for adults are diarrhea, fatigue and weight loss. Adults may also experience bloating and gas, abdominal pain, nausea, constipation, and vomiting. However, more than half of adults with celiac disease have signs and symptoms that are not related to the digestive system, including: - Anemia, usually resulting from iron deficiency - Loss of bone density (osteoporosis) or softening of bone (osteomalacia) - Itchy, blistery skin rash (dermatitis herpetiformis) - Damage to dental enamel - Mouth ulcers - Headaches and fatigue - Nervous system injury, including numbness and tingling in the feet and hands, possible problems with balance, and cognitive impairment - Joint pain - Reduced functioning of the spleen (hyposplenism) - Acid reflux and heartburn Children In children under 2 years old, typical signs and symptoms of celiac disease include: - Vomiting - Chronic diarrhea - Swollen belly - Failure to thrive - Poor appetite - Muscle wasting Older children may experience: - Diarrhea - Constipation - Weight loss - Irritability - Short stature - Delayed puberty - Neurological symptoms, including attention-deficit/hyperactivity disorder (ADHD), learning disabilities, headaches, lack of muscle coordination and seizures Dermatitis herpetiformis Dermatitis herpetiformis is an itchy, blistering skin disease that stems from intestinal gluten intolerance. The rash usually occurs on the elbows, knees, torso, scalp and buttocks. Dermatitis herpetiformis is often associated with changes to the lining of the small intestine identical to those of celiac disease, but the disease may not produce noticeable digestive symptoms. Doctors treat dermatitis herpetiformis with a gluten-free diet or medication, or both, to control the rash. When to see a doctor Consult your doctor if you have diarrhea or digestive discomfort that lasts for more than two weeks. Consult your child's doctor if your child is pale, irritable or failing to grow or has a potbelly and foul-smelling, bulky stools. Be sure to consult your doctor before trying a gluten-free diet. If you stop or even reduce the amount of gluten you eat before you're tested for celiac disease, you may change the test results. Celiac disease tends to run in families. If someone in your family has the condition, ask your doctor if you should be tested. Also ask your doctor about testing if you or someone in your family has a risk factor for celiac disease, such as type 1 diabetes. PreviousNext Causes Celiac disease occurs from an interaction between genes, eating foods with gluten and other environmental factors, but the precise cause isn't known. Infant feeding practices, gastrointestinal infections and gut bacteria might contribute to developing celiac disease. Sometimes celiac disease is triggered — or becomes active for the first time — after surgery, pregnancy, childbirth, viral infection or severe emotional stress. When the body's immune system overreacts to gluten in food, the reaction damages the tiny, hair-like projections (villi) that line the small intestine. Villi absorb vitamins, minerals and other nutrients from the food you eat. If your villi are damaged, you can't get enough nutrients, no matter how much you eat. Some gene variations appear to increase the risk of developing the disease. But having those gene variants doesn't mean you'll get celiac disease, which suggests that additional factors must be involved. The rate of celiac disease in Western countries is estimated at about 1 percent of the population. Celiac disease is most common in Caucasians; however, it is now being diagnosed among many ethnic groups and is being found globally. PreviousNext Risk factors Celiac disease can affect anyone. However, it tends to be more common in people who have: PreviousNext - A family member with celiac disease or dermatitis herpetiformis - Type 1 diabetes - Down syndrome or Turner syndrome - Autoimmune thyroid disease - Microscopic colitis (lymphocytic or collagenous colitis) - Addison's disease - Rheumatoid arthritis Complications Untreated, celiac disease can cause: - Malnutrition. The damage to your small intestine means it can't absorb enough nutrients. Malnutrition can lead to anemia and weight loss. In children, malnutrition can cause slow growth and short stature. - Loss of calcium and bone density. Malabsorption of calcium and vitamin D may lead to a softening of the bone (osteomalacia or rickets) in children and a loss of bone density (osteoporosis) in adults. - Infertility and miscarriage. Malabsorption of calcium and vitamin D can contribute to reproductive issues. - Lactose intolerance. Damage to your small intestine may cause you to experience abdominal pain and diarrhea after eating lactose-containing dairy products, even though they don't contain gluten. Once your intestine has healed, you may be able to tolerate dairy products again. However, some people continue to experience lactose intolerance despite successful management of celiac disease. - Cancer. People with celiac disease who don't maintain a gluten-free diet have a greater risk of developing several forms of cancer, including intestinal lymphoma and small bowel cancer. - Neurological problems. Some people with celiac disease may develop neurological problems such as seizures or peripheral neuropathy (disease of the nerves that lead to the hands and feet). In children, celiac disease can also lead to failure to thrive, delayed puberty, weight loss, irritability and dental enamel defects, anemia, arthritis, and epilepsy. Nonresponsive celiac disease As many as 30 percent of people with celiac disease may not have, or be able to maintain, a good response to a gluten-free diet. This condition, known as nonresponsive celiac disease, is often due to contamination of the diet with gluten. Therefore it's important to work with a dietitian. People with nonresponsive celiac disease may have additional conditions, such as bacteria in the small intestine (bacterial overgrowth), microscopic colitis, poor pancreas function, irritable bowel syndrome or intolerance to disaccharides (lactose and fructose). Or, they may have refractory celiac disease. Refractory celiac disease In rare instances, the intestinal injury of celiac disease persists and leads to substantial malabsorption, even though you have followed a strict gluten-free diet. This combination is known as refractory celiac disease. If you continue to experience signs and symptoms despite following a gluten-free diet for six months to one year, your doctor may recommend further testing and look for other explanations for your symptoms. Your doctor may recommend treatment with a steroid to reduce intestinal inflammation, or a medication that suppresses your immune system. All patients with celiac disease should be followed up to monitor the response of their disease to treatment. PreviousNext Diagnosis Researchers estimate that only 20 percent of people with celiac disease may receive a diagnosis. Doctors may order two blood tests to help diagnose celiac disease. - Serology testing looks for antibodies in your blood. Elevated levels of certain antibody proteins indicate an immune reaction to gluten. - Genetic testing for human leukocyte antigens (HLA-DQ2 and HLA-DQ8) can be used to rule out celiac disease. If the results of these tests indicate celiac disease, your doctor may order an endoscopy to view your small intestine and to take a small tissue sample (biopsy) to analyze for damage to the villi. It's important to be tested for celiac disease before trying a gluten-free diet. Eliminating gluten from your diet may change the results of blood tests so that they appear to be normal. PreviousNext Treatment A strict, lifelong gluten-free diet is the only way to manage celiac disease. In addition to wheat, foods that contain gluten include: - Barley - Bulgur - Durum - Farina - Graham flour - Malt - Rye - Semolina - Spelt (a form of wheat) - Triticale Your doctor may refer you to a dietitian, who can help you plan a healthy gluten-free diet. Once you remove gluten from your diet, inflammation in your small intestine generally begins to lessen — usually within several weeks, though you may start to feel better in just a few days. Complete healing and regrowth of the villi may take several months to several years. Healing in the small intestine tends to occur more quickly in children than adults. If you accidentally eat a product that contains gluten, you may experience abdominal pain and diarrhea. Some people experience no signs or symptoms after eating gluten, but this doesn't mean it's not harmful to them. Even trace amounts of gluten in your diet can be damaging, whether or not they cause signs or symptoms. Hidden gluten can be present in foods, medications and nonfood products, including: - Modified food starch, preservatives and food stabilizers - Prescription and over-the-counter medications - Vitamin and mineral supplements - Herbal and nutritional supplements - Lipstick products - Toothpaste and mouthwash - Envelope and stamp glue - Play-Doh Vitamin and mineral supplements If your nutritional deficiencies are severe, your doctor or dietitian may recommend taking vitamin and mineral supplements. You may need to supplement your levels of: - Calcium - Folate - Iron - Vitamin B-12 - Vitamin D - Vitamin K - Zinc Vitamins and supplements are usually taken in pill form. If your digestive tract has trouble absorbing vitamins, your doctor may give them by injection. You need to be sure that the vitamins and supplements are gluten-free. Follow-up care If you have celiac disease, you will need medical follow-up to make sure your symptoms have responded to a gluten-free diet. Doctors will also want to be sure you are getting the support you need to maintain the diet for life. They will use blood tests to monitor your response. The results of these tests, which are primarily designed as a way to detect celiac disease, usually become negative once you have been gluten-free for six to 12 months. If test results remain positive, then your doctor may try to find the reason, the most common being unintentional exposure to gluten in your diet. However, these tests are not perfect, and even if the results become negative, it is possible that you could still be exposed to a significant amount of gluten and continue to have symptoms and damage to your intestines. If you continue to have symptoms, or your symptoms recur, you may need a follow-up endoscopy with biopsies to ensure that healing has occurred. Adults typically have a greater need for follow-up testing, although children may require it, too. Some doctors recommend a routine re-biopsy if you are diagnosed in adulthood, as healing is often quite slow and uncertain. It also can be helpful to follow up with an expert dietitian for assistance in adapting to, and maintaining, a healthy, nutritious, gluten-free diet. Medications to control intestinal inflammation If your small intestine is severely damaged, your doctor may recommend steroids to control inflammation. Steroids can ease severe signs and symptoms of celiac disease while the intestine heals. Dermatitis herpetiformis If you have this itchy, blistering skin rash that sometimes accompanies celiac disease, your doctor may recommend a skin medication (dapsone) along with the gluten-free diet. Refractory celiac disease If you have refractory celiac disease, you may continue to have severe symptoms, or your symptoms may lessen but then relapse. In either case, your small intestine does not heal. When this happens, you likely will require evaluation in a specialized center. Refractory celiac disease can be quite serious and there is currently no proven treatment. People with refractory celiac disease should be treated by experts. There may be several causes for this condition. Doctors will often use steroid therapy — either a topical budesonide or systemic steroids such as prednisone. Sometimes, they will use the same medications used to treat other conditions. Potential future treatments While the only proven therapy for celiac disease is a gluten-free diet, it is not perfect. People with celiac disease may often be accidentally exposed to gluten, possibly causing severe symptoms. Several treatments are in development for celiac disease. Some try to neutralize or bind to gluten. Others address the barrier of the intestine, blocking the leakiness that gluten can trigger. Still others target the body's immune system. Researchers have also been trying to genetically modify wheat, but have not yet been successful. None of these treatments is likely to be approved within the next two to three years. However, given the number of different approaches, there is a good chance that there will be additional treatments available for celiac disease in the future. PreviousNext Alternative medicine There are no proven treatments that assist with celiac disease. Enzyme therapies that claim to digest gluten may be available in health food stores or other outlets, but there is no scientific evidence that they are effective in treating celiac disease. PreviousNext Preparing for an appointment You may be referred to a doctor who treats digestive diseases (gastroenterologist). Here's some information to help you prepare for your appointment and know what to expect from your doctor. What can you do - Continue eating a normal diet. If you stop or reduce eating gluten before you're tested for celiac disease, you may change the test results. - Write down your symptoms. Include when they started and how they may have changed over time. - Write down key personal information. Include any major stresses or recent life changes. - Make a list of all medications. Include vitamins or supplements that you're taking. - Write down questions to ask your doctor. Questions to ask your doctor Some basic questions to ask your doctor include: - What's the most likely cause of my symptoms? - Is my condition temporary or long term? - What kinds of tests do I need? - What treatments can help? - Are there any dietary restrictions that I need to follow? - How will I learn which foods contain gluten? Should I see a dietitian? - If I have celiac disease, will you also test for other conditions such as vitamin or mineral deficiencies, osteoporosis or diabetes? Don't hesitate to ask other questions during your appointment. What to expect from your doctor Be ready to answer questions your doctor may ask: PreviousNext - When did you first begin experiencing symptoms, and how severe are they? - Have your symptoms been continuous or occasional? - What, if anything, seems to improve your symptoms? - What, if anything, seems to worsen your symptoms? - What medications and pain relievers do you take? - Does anyone in your family have celiac disease? - Do you or does anyone in your family have an autoimmune disorder? - Have you had any blistering or itchy skin rashes with your symptoms? - Have you ever been diagnosed with anemia or osteoporosis? Lifestyle and home remedies If you've been diagnosed with celiac disease, you'll need to avoid all foods that contain gluten. Ask your doctor for a referral to a dietitian, who can help you plan a healthy gluten-free diet. It's important to get enough vitamins, nutrients, fiber and calcium in your diet. Here's an overview of foods that contain gluten and gluten-free foods that are safe to eat. Always avoid Avoid food and drinks containing: - Barley - Bulgur - Durum - Farina - Graham flour - Malt - Rye - Semolina - Spelt (a form of wheat) - Triticale - Wheat Read labels Packaged foods should be avoided unless they're labeled as gluten-free or have no gluten-containing ingredients. In addition to cereals, pastas and baked goods — such as breads, cakes, pies and cookies — other packaged foods that may contain gluten include: - Beer - Candies - Gravies - Imitation meats or seafood - Processed luncheon meats - Salad dressings and sauces, including soy sauce - Self-basting poultry - Soups Certain grains, such as oats, can be contaminated with wheat during growing and processing. Pure oats are not harmful for most people with celiac disease. In the United States, doctors generally recommend avoiding oats unless they have been specifically labeled gluten-free. Outside of the United States, different labeling laws for oats apply. Occasionally, even pure oats can be a problem for people with celiac disease. Allowed foods Many basic foods are allowed in a gluten-free diet, including: - Fresh meats, fish and poultry that aren't breaded, batter-coated or marinated - Fruits - Most dairy products - Potatoes - Vegetables - Wine and distilled liquors, ciders and spirits Grains and starches allowed in a gluten-free diet include: - Amaranth - Arrowroot - Buckwheat - Corn - Cornmeal - Gluten-free flours (rice, soy, corn, potato, bean) - Pure corn tortillas - Quinoa - Rice - Tapioca Carob is a potential substitute for gluten, but more research is needed about its effect on people with celiac disease. Fortunately for bread and pasta lovers with celiac disease, an increasing number of gluten-free products are available. If you can't find any at your local bakery or grocery store, check online. There are gluten-free substitutes for many gluten-containing foods. However, be aware that processed gluten-free foods may contain excessive fat and calories. PreviousNext Coping and support It can be difficult, and stressful, to follow a completely gluten-free diet. Here are some ways to help you cope and to feel more in control. Previous - Get educated. Educate those around you — including family and friends — so they can recognize, acknowledge and support your efforts in dealing with the disease. - Follow your doctor's recommendations. If you are diagnosed with celiac disease, it's necessary to maintain a totally gluten-free diet. - Find a support group. It's helpful to know that you're not alone. You may find comfort in sharing your experience and struggles and meeting people who face similar challenges. Organizations such as the Celiac Disease Foundation, Gluten Intolerance Group, the Celiac Support Association and Beyond Celiac can help put you in touch with others who have had similar experiences and can understand what you're going through.
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Celijakija sprue : uzroci , simptomi , dijagnoza , liječenje Gastroenterologija / / August 12, 2017 Celiac sprue - nasljedna bolest nepoznate etiologije, krše probavni (crijevne apsorpcije) uzrokovana oštećenja tankog crijeva Neke namirnice (pšenica, ječam, raž i eventualno zob), koji sadrži proteine gluten žitarica gluten i koji su mu bliski proteini žitarica- avenin, hordeinske itd i abnormalne crijevne nemogućnost probaviti gluten i, posebno, jedan od glavnih sastojaka glutena -. glutenski epitopi.To je mješoviti autoimuna, alergijski, nasljedna geneza, naslijedio u autosomno dominantan način. Alternativni nazivi: sprue;netropska crijevna bolest;crijevna infantilizam;celijakija;nepodnošenje glutena;glutenska enteropatija;Gee bolest;glyutenochuvstvitelnaya enteropatija. Celiac sprue je rasprostranjena među autohtonog stanovništva Dalekog i Bliskog istoka, Indije, rodom iz Južne Afrike, Zimbabvea i na Karibima.To također može utjecati na Europljane koji su migrirali u tim zemljama, a njegovi znakovi mogu trajati dugi niz godina.Jedina manifestacija kronične bolesti povreda asimilaciju vitamina liječenje - prehrambene korekcija nedostatak i uvođenje širokog spektra tipa antibiotik tetraciklin.Nakon svakog tretmana treba ponoviti test nakon apsorpciju vitamina B12.U ekstremnim slučajevima, sprue propisati steroidnih hormona i steroida.U kroničnim slučajevima, sprue ne preporučuje da ostanu u zemljama s tropskom klimom.U razvoju bolesti igraju značajnu ulogu imunoloških poremećaja. Uzroci i faktori rizika za celijakija sprue Točan uzrok celijakije spru je nepoznat.Plast crijevnih resica je pomoći apsorbirati hranjive tvari.Kad ljudi s celijakijom jesti hranu koja sadrži gluten, njihov imunološki sustav reagira na oštećenja resica.Štete utjecati na sposobnost apsorpcije hranjivih tvari ispravno.Čovjek potpuno zasićen - bez obzira koliko hrane jede. Bolest se može razviti u bilo kojem trenutku u životu, od djetinjstva do kasne odrasle dobi. Ljudi koji imaju člana obitelji s celijakijom imaju veći rizik od razvoja bolesti.Poremećaj se najčešće javlja u bijelaca i ljudi europskog podrijetla.Žene su pogođene češće od muškaraca. Osobe s celijakije vjerojatno da su sljedeće bolesti: - autoimune bolesti - kao što je reumatoidni artritis, sistemski eritematozni lupus, Sjogrenov sindrom; - Addisonova bolest (kronična adrenalna insuficijencija, ili gipokortitsizm); - Downov sindrom; - rak debelog crijeva (ili rak debelog crijeva, - crijevna limfoma (rijedak zloćudni tumor tankog i debelog crijeva); - laktoza netolerancije (ili hypolactasia) - štitnjača bolesti; - tip 1 šećerne bolesti (dijabetes ovisan o inzulinu, juvenilni dijabetes); Simptomi celijakije sprue Simptomi celijakije u različitim pojedincima mogu varirati To je jedan od razloga zašto se dijagnoza nije uvijek staviti odjednom, na primjer, jedna osoba može imati zatvor, drugi - proljev, a treći ne može imati sve ... nema problema sa stolca Gastrointestinalni simptomi uključuju: - bolovi u trbuhu, nadutost, plinove, prevrnut želuca, - zatvor, - smanjen apetit (i apetit može biti povećana ili nepromijenjena); - proljev- stalno ili povremeno; - laktoza intolerancija (često kada se dijagnosticira osoba, obično nestaje nakon tretmana); - mučnina i povraćanje; - proljev, koji ima neugodan miris, masnu ili krvav; - neobjašnjen gubitak težine (iako su ljudi u isto vrijeme i mogu biti pretili ili normalne težine). S obzirom na činjenicu da se crijeva ne apsorbiraju puno važnih vitamina, minerala i drugih dijelova hrane, sljedeći simptomi se mogu pojaviti za dugo vremena: - blagi vrtoglavicu; - depresija ili anksioznost; - umor; - usporava rast (kod djece); - gubitak kose; - svrbež kože; - dugo menstrualnog perioda; - usta čireve; - grčevi mišića i bol u zglobovima; - krvarenje iz nosa; - bockanje ili utrnulost u rukama ili nogama, itd Djeca s celijakijom mogu imati simptome kao: - nedostaci u zubnu caklinu i diskoloraciju zubi; - odgođen pubertet; - proljev, zatvor, masna ili smrdljive stolice, mučnina ili povraćanje; - iritacija i nemir u ponašanju; - snažan porast težine; - sporiji rast ili rast ispod normalne visine za svoju dob. dijagnoza celijakija sprue - albumin (može biti niska); - alkalna fosfataza; - zgrušavanja abnormalnosti faktor (faktori zgrušavanja - skupinu kemikalija pronađena u trombocitima i plazmi i osiguranje kolaps); - provjera može sniziti kolesterol; - kompletna krvna slika (test za anemija); - analiza jetrenih enzima; - protrombinsko vrijeme krvni testovi mogu otkriti neke specifično antitijelo, pod nazivom "razredi antitijela IgA da transglutaminaze tkiva" (ili tTG protutijela protiv transglutaminaze, imunoglobulini klase G - određivanje klase seruma G imunoglobulina za transglutaminaze enzim tkiva je osjetljiva ispecifična metoda za dijagnosticiranje celijakije u bolesnika s imunoglobulina izolirani nedostatak A. temu GFD i postizanje remisije koncentraciju protutijela postupno se smanjuje, a može postati negativna analiza zašto istraživanja o anti-TG, IgG može se koristiti za procjenu pacijentovog prianjanje na glutena-free dijetai test krvi se preporučuje da se ova dijeta).Liječnik propisuje tih testova antitijela, ako se sumnja celijakija. Ako je test uspješan, obično izvode endoskopiju i biopsija (analiza uzoraka tkiva komada) iz prvog dijela tankog crijeva (duodenum).Biopsija se može pokazati pečat u crijevnom resica ispod duodenuma. ispitivanje genetski krvi također može pomoći u određivanju što može biti opasno za celijakije. naknadno biopsija ili test krvi može se dodijeliti samo nekoliko mjeseci nakon dijagnoze i liječenja.Ovi testovi pomoći će testirati na odgovor tijelu pacijenta za liječenje.Normalno znači da je pacijent reagirao na liječenje, dijagnoza je potvrđena.Međutim, to ne znači da se bolest u potpunosti izliječiti. Liječenje celijakija sprue Celijakija se ne može izliječiti do kraja.Međutim, simptomi nestaju nakon odgovarajućeg tretmana, a resice u crijevne sluznice izliječi, ako to pacijent će biti tijekom svog života slijediti gluten-free dijeta: neće jesti hranu, piti pića i lijekova koji sadrže pšenicu, ječam, raž, i,možda i zob. Ako pacijent - celijakija, važno je da je konzultirao nadležnog dijetetičara koji se bavi celijakije i bezglutenske prehrane.Stručnjak može reći pacijentu, gdje se mogu kupiti bezglutenski proizvodi i podijeliti važne informacije koje će objasniti bolest i njegove metode liječenja. dijetetičar može dati savjete o uvjetima koji se obično nalaze zajedno s celijakijom - kao što su: - dijabetes; - netolerancija laktoze; - vitamina ili manjak mineralnih; - gubitak težine ili dobitak. Preporučeni celijakije pacijentima da pažljivo pročitate hrane i lijekova naljepnice proizvoda otkriti skrivene izvore koji sadrže gluten (glutena), žitarice i sastojaka koji su povezani s njima.Promatrajući disciplinu i planiranje obroka, pacijent će se oporaviti relativno. No, ne smijemo započeti dijetu bez glutena prije postavljanja dijagnoze "celijakija" ( "sprue").Dijeta utjecati dijagnostičke pokazatelje bolesti. liječnik može propisati pacijentu s vitaminom celijakija i mineralnih dodataka ispraviti nedostatke u prehrani.Ponekad kortikosteroide (kao što je prednizon) može također biti propisan za kratkoročni uporabu.Nakon dobro uravnotežen bezglutenske prehrane, u pravilu, samo trebate nadležno postupanje. Kada pacijent s "celijakija" dijagnoza, on može konzultirati dijetetičara koji se bavi celijakije i bezglutenske prehrane.Podrška skupine također može pomoći pacijentu nositi s bolesti i prehrane. P Projekcija celijakija sprue bezglutenske prehrane liječi crijevne štetu i spriječiti daljnje štete.Liječenje se obično javlja u roku od 3-6 mjeseci u djece, ali može potrajati 2-3 godina u odraslih. rijetko dugoročno oštećenje crijevne sluznice će biti učinjeno prije dijagnoze. Neki problemi uzrokovani celijakije neće otići - na primjer, problemi s rastom i oštetiti zube. Vezani članci: - gluten-free dijeta za celijakija - cjelovitu istinu o glutena - korisnih i štetnih proizvoda za jetru - jednostavnih i složenih ugljikohidrata: oni nas - Anemija je potrebno: uzroci, simptomi, liječenje, prevencija Komplikacije celijakije sprue pacijenta mora sav život i dalje pozorno pratiti gluten-free dijeta.Ako se ne liječi, bolest može izazvati komplikacije, opasne po život. odgađanje ili odsustvo ispravnu dijagnozu nakon dijeta će dostaviti pacijenta na rizik povezan s celijakijom - kao što su na primjer: - autoimune bolesti; - koštane bolesti: osteoporoza, kifoze, česti lomovi; - određene vrste raka debelog crijeva; - niska razina hemoglobina (nedovoljan broj crvenih krvnih stanica) u krvi (anemija); - niska razina šećera u krvi (hipoglikemija); - neplodnost ili ponavlja pobačaj; - bolesti jetre. preporučamo da se obratite liječniku ako postoje simptomi celijakije. Prevencija celijakija sprue Budući da je točan uzrok celijakija je nepoznat, ne postoji poznati način da se spriječi njegov razvoj.Međutim, u fazi rane dijagnoze i znanja liječenja čimbenika rizika (primjerice, u prisustvu člana obitelji s poremećajem) mogu povećati šanse za dugo zdrav život.