http___metro-portal.hr_zaboravite-na-sve-lose-uz-pilulu-koja-brise-negativna-sjecanja_41749_1.xml
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If there existed a pill that could take all the pain away, would you take it? Hmmm. Would I? Forgetting an unhappy love affair or a traumatic accident could soon be as easy as popping a pill. At the risk of being accused of developing a pill for everything, scientists have discovered a drug that helps numb the pain of bad memories by flooding the mind with feelings of security and safety. And the technique could one day be used to cure phobia sufferers of their fears, help soldiers recover from the horrors of battle or allow accident victims to put their trauma behind them. To test the effectiveness of the drug, researchers created bad memories by giving mice electric shocks while a loud noise was played. Over time, the creatures learned to associate the sound with the shock, and hearing the noise alone was enough to make them freeze. But when they were given a drug called brain-derived neurotrophic factor, or BDNF, they lost their fear, the journal Science reports. The effect of the drug was similar to a psychological technique called extinction training, in which phobia sufferers are repeatedly exposed to their nemesis in a bid to desensitise them to it. The U.S. government-funded researchers believe that, as in extinction training, the drug did not erase the bad memory completely, but created a sense of safety and positivity that made it easier to cope with. They think it does this by triggering the growth of connections between cells in a part of the brain that is crucial in dealing with phobias. BDNF is naturally produced in the brain, and experiments showed that rats with a shortage of the compound struggled to overwrite bad memories. Failure to overwrite fear is thought to contribute to post-traumatic stress disorder, as well as other psychological problems. Prozac also raises levels of BDNF, but the researchers believe that more effective drugs could be developed to tackle fears and phobias. Dr Thomas Insel of the National Institute of Mental Health, which financed the research, said: ‘Many lines of evidence implicate BDNF in mental disorders. ‘This work supports the idea that medications could be developed to augment the effects of BDNF, providing opportunities for pharmaceutical treatment of post-traumatic stress disorder and other anxiety disorders.’ A drug that boosts levels of BDNF in the brain might also help people tackle addictions. The researchers, from the University of Puerto Rico, will now look into the possibility of creating such a pill – and will also study whether exercise could be beneficial in dealing with fear. The ability to erase painful memories has been the stuff of science fiction and Hollywood blockbusters for decades. In the film Eternal Sunshine Of The Spotless Mind, a couple, played by Kate Winslet and Jim Carrey, undergo a procedure known as ‘targeted memory erasure’ to wipe out all recollection of each other after their relationship turns sour. Last year, Dutch researchers discovered that beta-blocker drugs used to treat heart disease may also help patients to banish bad memories. And scientists have shown that maintaining a stiff upper lip in times of crisis can stop bad memories from being laid down. Those who refuse to panic during moments of trauma remember less about what they saw than people who are more emotional. It is thought that by concentrating so hard on keeping their emotions in check, they overload their brain, stopping it from taking in what is happening. But the field is not without its critics, with some claiming that holding on to and reviewing bad memories is essential if we are to learn from our mistakes. And because of that last statement in this article, I must say, the answer for me – Would I take the pill? Definitely not. Sometimes… Mistakes? Pain? Life? It’s suppose to hurt. Like my Father always says, “Pain. It’s the best teacher there is.” And he’s not wrong.
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Zaboravite na sve loše uz pilulu koja briše negativna sjećanja Zaboravljanje nesretne ljubavi ili traumatske nesreće moglo bi biti jednostavno poput gutanja pilule Naime, znanstvenici su izumili upravo pilulu koja koja pomaže ublažavanju boli negativnih sjećanja preplavljujući um emocijama sigurnosti i smirenosti. Ova tehnika jednog bi se dana mogla koristiti za izlječenje od raznih fobija, pomoći vojnicima da se oporave od užasa rata ili omogućiti žrtvama nesreće da ostave traume iza sebe. Kako bi testirali efektivnost lijeka, istraživači su stvorili loša sjećanja kod miševa dajući im elektrošokove te puštajući glasnu muziku. Tijekom vremena životinje su naučile povezivati zvuk sa strahom i šokom, no kad im je dan lijek po imenu BDNF, riješile su se svih negativnih emocija. Efekt lijeka sličan je psihološkoj tehnici koja se zove trening izumiranja, tijekom čega se pacijenti koji pate od fobija konstantno izlažu svojim strahovima kako bi očvrsnuli. Znanstvenici, čije istraživanje financira vlada SAD-a, vjeruju da lijek zapravo ne briše loša sjećanja, već stvara pozitivne emocije uz koje se lakše s njima nositi. Smatraju kako do tog efekta dolazi stimuliranjem rasta veza među stanicama u dijelu mozga koji je odgovoran za fobije. BDNF se također prirodno proizvodi u mozgu, a eksperimenti na štakorima pokazali su kako životinje s nedostatkom tog faktora imaju problema u nošenju s negativnim sjećanjima. Nesposobnost da se nadvlada strah pripisuje se i posttraumatskom stresnom poremećaju i psihološkim problemima. Prozac također podiže nivo BDNF-a, no znanstvenici vjeruju kako se može razviti puno efektniji lijek za borbu protiv fobija. Thomas Insel koji je radio na istraživanju dodaje: "Ova studija podržava ideju da se mogu razviti lijekovi koji pojačavaju efekte BDNF-a, čime se otvaraju mogućnosti za liječenje mnogih psihičkih poremećaja."