http___metro-portal.hr_oprez-lijekovi-protiv-kolesterola-uzrokuju-secernu-bolest_67197_1.xml
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Lipitor Lipitor® (atorvastatin calcium) is a drug that is prescribed to lower cholesterol. It should be combined with a healthy diet and exercise. People with high levels of cholesterol are at risk for atherosclerotic disease. Lipitor, in addition to a proper diet, is prescribed for adult patients with the following risk factors for atherosclerosis: - Advanced age - Smoking - High blood pressure - Low HDL-C (high density lipoprotein-C, or the "good lipoprotein") levels, which are a measure of certain types of fat in the blood. - Family history of early coronary heart disease The purpose of the medication is to reduce: - The risk of heart attack - The risk of stroke - The need for surgical procedures to improve clogged blood vessels - The occurrence of angina or chest pain due to cardiovascular problems Diabetes, Lipitor and Older Women The U.S. Food and Drug Administration (FDA) added a new warning to the drug label of Lipitor to alert patients that the risk for developing Type 2 diabetes has increased slightly in some patients taking Lipitor as well as some other statin drugs. An association has been shown between taking these drugs and increased levels of sugar in the blood, which may be a precursor to diabetes. "A small increased risk of raised blood sugar levels and the development of Type 2 diabetes have been reported with the use of statins," the FDA warning says. The FDA previously issued a similar warning for another statin, Crestor, but decided in February 2012 to add the warning to the labels of all statin drugs, except for Pravachol. That medication was shown in a clinical trial to reduce the risk of developing diabetes by 30 percent. However, other studies indicated the drug was less effective in reducing the risk of heart disease. The Women's Research Institute at Northwestern University published data indicating a strong correlation between postmenopausal women who take statins and an almost 50 percent greater risk of Type 2 diabetes than those not taking cholesterol-lowering drugs. The data were taken from the women in the Women's Health Initiative when they entered the study. The research was conducted by Yunsheng Ma, MD, PhD, of the University of Massachusetts School of Medicine and his colleagues and published in the Archives of Internal Medicine. The scientists looked at data on 153,840 women averaging 63 years old, who did not have diabetes when they entered the study in 1993. About 7 percent of these women were taking statins at that time. When follow-up data were examined in 2005, the number of new-onset cases of diabetes was 10,242. The risks were seen with all types of statins used in all ethnicities. The highest risk was among Asian women. According to the study's authors: - Women taking statins should be tested for diabetes and liver dysfunction - Doctors may be prescribing too many statins and should be encouraging more changes in lifestyle, such as exercise and diet In the same Northwestern article, another researcher, Suzanne Steinbaum, MD, wrote in an email to the authors that the results of just one study don't give a clear representation of what the implications are for postmenopausal women taking statins. Steinbaum is director of women and heart disease at Lenox Hill Hospital in Bronx, New York. "Due to the extensive use of statins in the aging female population," Steinbaum wrote, "it is critical that more studies are done to help understand the association with statins and the development of diabetes. "Women who are taking statins should be aware of the need to check their blood sugars, along with their liver function tests." Other Side Effects of Lipitor The FDA has also warned of other side effects that occur in patients taking statins. In February 2012, the FDA announced that Lipitor and other statins increased the risk not only for diabetes, but also for memory loss, muscle pain and a low risk of liver damage. Some of the more common side effects include diarrhea, upset stomach, muscle pain and changes in blood tests. Doctor's should evaluate a patient's medical history before prescribing Lipitor. If you are taking Lipitor, you should understand the potential risks and their symptoms and should seek medical attention if you show signs of increased blood sugar and muscle damage. If you have been diagnosed with Type 2 diabetes after taking Lipitor, or have experienced another ill side effect of the medication, contact us to speak with a defective drug lawyer today. You may qualify for compensation. Lipitor® (atorvastatin calcium) is manufactured by Pfizer Inc. Lipitor is a registered trademark of Pfizer. Need Legal Help? Contact us for free information or to start a free case review.
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Oprez - lijekovi protiv kolesterola uzrokuju dijabetes u žena Istraživanje je utvrdilo kako su žene koje su uzimale statine imale gotovo 50 posto veće izglede za to da im se postavi dijagnoza dijabetesa Nedavno je američko istraživanje pokazalo kako bi lijekovi za snižavanje kolesterola, statini, mogli biti povezani s povećanim rizikom od šećerne bolesti kod žena između 50 i 70 godina, javlja Hina. Istraživanje, objavljeno u časopisu Archives of Internal Medicine, utvrdilo je da su žene koje su uzimale statine na početku višegodišnjeg istraživanja imale gotovo 50 posto veće izglede za to da im se postavi dijagnoza dijabetesa od onih koje nisu uzimale statine. "Liječenje statinom kod žena u postmenopauzi povezano je s povećanim rizikom za šećernu bolest", napisao je Yunsheng Ma s medicinskog fakulteta Sveučilišta u Massachusettsu. Znanstvenici su obradili podatke o oko 150 tisuća žena u dobi od 50 do 70 godina i utvrdili su da se šećerna bolest pojavila kod njih 10 tisuća s tim da su se izgledi za tu bolest bili 48 posto veći kod žena koje su uzimale statine. Znanstvenici su pri tom isključili druge faktore rizika za pojavu šećerne bolesti. Ranija istraživanja pokazala su da se vjerojatnost za obolijevanje od šećerne bolesti kod muškaraca povećava za 10 do 12 posto među korisnicima statina. Stručnjaci još nisu otkrili razloge te veze a preporučuju osobama koje uzimaju statine da gube na težini i više vježbaju kako bi smanjili rizike za pojavu šećerne bolesti.