http___www.kinderwunschklinik.at_hr_lijecenje_mogucnosti_lijecenja_spindleview__1.xml
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SpindleView The spindle plays a central role in the eggs cells. The spindle is responsible for accurate alignment and distribution of the chromosomes during cell division. The spindle is however in danger of being damaged by the injection of the needle during ICSI treatment. For this reason, we’ve implemented a technological innovation at the IVF laboratory of the KinderWunschKlinik Vienna. This SpindleView technique makes the spindle clearly visible. In this way, any damage to the spindle during the ICSI procedure or during the polar body biopsy can be avoided. Several studies have shown that the absence of the spindle correlates with a significantly reduced fertilization rate and with a lower development potential of the embryo. Consequently, the spindle is an excellent marker when determining a cell’s ability to live and develop. Furthermore, data from trials hypothesize that the location and/or the position of the spindle during the ICSI has an influence on the further development of the egg cell. Even morphological parameters of the egg cell can be determined using SpindleView. The SpindleView system automatically records data regarding the thickness of the egg cell's outer layer, the position as well as the thickness of the layers. This data is then evaluated in order to be able to better assess the quality of various egg cells.
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SpindleView SpindleView u klinici KinderWunschKlinik u Beču Takozvani „vretenasti aparat“ ima važnu funkciju u jajnoj stanici. On se brine za to da se kromosomi prilikom dijeljenja stanice pravilno raspodjele. Vretenasti aparat je međutim ugrožen prodiranjem igle prilikom ICSI-tretmana. Zbog toga smo u laboratoriju za in vitro oplodnju u klinici KinderWunschKlinik u Beču uveli jednu tehnološku inovaciju. Ova SpindleView tehnika omogućava da vretenasti aparat postane vidljiv. Time se može izbjeći ozljeđivanje vretenastog aparata prilikom ICSI mjere, kao i prilikom biopsije polarnog tijela. Više studija je takođe potvrdilo da je odsustvo vretena povezano sa znatno smanjenom stopom oplodnje i lošijim razvojnim potencijalom zametaka. Time je vreteno izuzetan marker za određivanje životne i razvojne sposobnosti jedne jajne stanice. Osim toga, podaci iz studija navode na pretpostavku da položaj, odnosno usmjerenost vretena za vrijeme ICSI utiče na dalji razvoj jajne stanice. Pomoću SpindleView tehnike mogu se odrediti i morfološki parametri na jajnoj stanici SpindleView sistem automatski prima podatke o gustoći vanjske kože jajne stanice , o usmjerenosti kao i o debljini slojeva. Ovi podaci se ocjenjuju kako bi se bolje mogao procijeniti kvaliteta različitih jajnih stanica.