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Cervical cancer is not something that happens to “other women only” 18.81 million SA women over the age of 15 are at risk The subject of cervical cancer has not received nearly as much attention as other life-threatening illnesses affecting women, says Dr Thandi Mtsi, a gynaecologist and obstetrician practising at Netcare Park Lane Hospital in Parktown, Johannesburg. “And yet, according to a recent report of the HPV Information Centre, as many as 7 735 South African women are diagnosed with cervical cancer every year while 4 248 lose their lives annually because of the disease,” she adds. The Human Papillomavirus and Related Disease Report published by the ICO HPV Information Centre on HPV and Cancer in February 2016, indicates than 18.81 million South African women, over the age of 15 are at risk of cervical cancer. “Given that approximately 80% of women will be exposed to the human papilloma virus in their lifetime, this is clearly not something that happens to ‘other’ women only. These statistics are all the more disconcerting when one considers that cervical cancer is nowadays a preventable disease,” points out Dr Mtsi. “With the aid of annual Pap smears and timeous vaccination against the cancer-causing human papillomavirus, a sexually transmitted infection, cervical cancer should have been totally eradicated by now.” “However, because of the incorrect perception that sexual promiscuity lies at the heart of this disease, it has been a difficult issue to tackle. Also of great concern, is the fact that girls are nowadays exposed to the virus at a younger age.” Vaccinations against the human papilloma virus (HPV) became part of the national vaccination programme in 2014 when SA became the first African country to fund cervical cancer vaccines for schoolgirls. While awareness of the importance of the Nobel Prize-winning HPV vaccine has grown, take-up has sadly been slow,” says Dr Mtsi. According to Dr Kim Lohlun, an oncologist at Netcare Olivedale Hospital, despite the fact that cervical cancer is a preventable disease, it causes more deaths in South African women than of any other type of cancer. “Vaccination against HPV is highly effective, but it is best to be vaccinated before becoming sexually active and it is recommended that girls as young as nine get vaccinated. However, it is never too late to get the injection, even though you may have come into contact with some of the HPV strains.” “The gold standard these days is the HPV test which checks for the virus that can cause these cell changes on the cervix. It may be used to screen for cervical cancer together with the Pap test and may also be used to provide more information when the results of a Pap smear are unclear. The HPV test is unfortunately not yet widely available and is also costly,” says Dr Lohlun. “Young women in their teens or early 20’s carry the highest rates of HPV infection. However, these are mostly cleared by the immune system. A positive HPV test in an older women is more likely to indicate persistent infection and this puts her more at risk of developing cervical cancer.” “At the advent of the HIV/AIDS outbreak, people were very hesitant talk about the disease, the HI virus and how it is transmitted. With the introduction of anti-retroviral treatment, which essentially rendered HIV infection a manageable ‘chronic disease’, this stigma was greatly reduced. In the same way, we now need to get discussions going on and spread awareness of HPV and cervical cancer. South African need to know that there is no shame in discussing this condition openly,” notes Dr Lohlun. What is the HPV? The human papilloma virus (HPV) is a double-stranded DNA virus. Up to 80 percent of sexually active women will acquire an HPV infection in their lifetime, with the risk of persistence increasing with age. Approximately 100 types of HPV have been identified to date and, of these, nearly 15 virus types are considered to cause cervical cancer. Together the highest-risk virus types 16 and 18 are responsible for over 70 percent of cervical cancers globally. “If you can protect yourself from getting an HPV infection, your chances of developing cervical cancer are miniscule,” says Dr Mtsi. How is the HPV transmitted? The virus is transmitted through sexual contact and in rare cases from a mother to her newborn baby, explains Dr Mtsi. Because the virus is not carried by bodily fluids but is transferred by contact, having protected sex will not give a hundred percent protection against becoming infected. This also means penetration does not have to take place before the HPV is transmitted – rubbing against your partner can be enough to contract the virus. What is the link between the HPV and cervical cancer? The high-risk HPV virus types are responsible for virtually all cervical cancer, which is cancer of the cervix, the small canal between the womb and the vagina. The more a woman comes into contact with the HPV, the greater her chances are of developing cervical cancer. “When your cervix is scarred from frequent infection, your cervical cells multiply to heal themselves. However, abnormal cells can multiply out of control as a result of the HPV infection and can cause pre-cancerous cervical lesions, which ultimately cause cervical cancer,” explains Dr Mtsi. What are the symptoms of cervical cancer? According to Dr Mtsi, there are no early symptoms for cervical cancer. “The first symptoms only appear as the disease progresses. Women should, however, look out for pain during sex, any change in their menstrual periods, an increased vaginal discharge and any abnormal vaginal bleeding,” she advises. According to Dr Lohlun cervical cancer can be difficult to treat if it is diagnosed at a late or advanced stage. If caught early, however, the disease can be very effectively treated. “This is why screening is so important. Treatment is either surgery or chemo-radiation, depending on how advanced the cancer is.” Fast facts - Cervical cancer is caused by a virus called human papilloma virus (HPV), which is transmitted through sexual activity. - HPV types 16 and 18 are the most common cancer-causing virus types and account for over 70% of all cervical cancer cases globally. - HPV types 16, 18, 31, 33 and 45 are the five most frequent cancer-causing HPV types, and are responsible for over 82% of cervical cancer cases globally. - The primary role of HPV vaccination is to protect women against cervical cancer. - The HPV vaccine provides highly effective and long-lasting protection against the most common and aggressive HPV types.
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Žene nedovoljno znaju o vezi HPV-a i raka cerviksa VELIK broj žena ne zna da je glavni uzrok raka cerviksa (vrata maternice) virus te da kontracepcijske pilule ne štite od te bolesti, objavili su britanski znanstvenici. Humani papilomavirus (HPV) povezan je s oko 95 posto cervikalnih karcinoma i jedan je od najčešćih uzročnika spolno prenosivih bolesti. Manje od trećine od tisuću žena ispitanih u jednoj londonskoj klinici u proteklih 15 mjeseci čulo je za HPV, a manje od polovice znalo je da je taj virus povezan s rakom. One koje su za to čule, starije su žene koje su imale patološki bris cerviksa. Prosječna dob ispitanica bila je 30 godina. "U tom razmjerno dobro obrazovanom uzorku, znanje o HPV-u je slabo", navodi Jo Waller sa Sveučilišta u Londonu u izvješću objavljenom u časopisu Sexually Transmitted Infections. Gotovo sve žene s rakom cerviksa imale su HPV, no istraživanja su pokazala da je mali postotak zaraženih oboljelo od raka. Taj virus uzrokuje i genitalne bradavice, najprepoznatljiviji simptom HPV infekcije. No, samo trećina ispitanih žena znala je da genitalne bradavice nisu uzrokovale rak cerviksa. "Potrebna je hitna edukacija javnosti, tako da žene koje sudjeluju u praćenju raka cerviksa budu potpuno informirane o svojim nalazima", zaključuje Waller.