http___www.krenizdravo.com_korisno_upute_euthyrox-50-uputa-kako-uzimati-nuspojave-cuvanje_1.xml
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WHAT DAONIL IS AND WHAT IT IS USED FOR The name of your medicine is Daonil 5mg Tablets. Daonil is a medicine taken by mouth to help lower blood sugar. It belongs to a group of medicines called sulfonylureas. Daonil works by increasing the amount of insulin released from your pancreas. The insulin then lowers your blood sugar levels. What Daonil is used for - Daonil is used to treat a certain form of diabetes (type 2 diabetes mellitus), when diet, physical exercise and weight reduction alone have not been able to control your blood sugar levels. WHAT YOU NEED TO KNOW BEFORE YOU TAKE DAONIL Do not take Daonil if: - You are allergic (hypersensitive) to glibenclamide, sulphonamides (medicines for bacterial infection) or any of the other ingredients of Daonil - You have insulin dependent diabetes (type 1 diabetes mellitus) - You have diabetic ketoacidosis (a complication of diabetes with some of the following signs: fatigue, nausea (feeling sick), frequent urination and muscular stiffness) - You are in a diabetic coma - You are pregnant - You are breast-feeding - You have severe problems with your kidneys - You have a severe liver disease - You are receiving a medicine called bosentan, used to treat high blood pressure Do not take this medicine if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking Daonil. Warnings and Precautions Take special care with Daonil Check with your doctor or pharmacist before taking your medicine if: - You are recovering from an injury, operation, infections with fever, or from other forms of stress, inform your doctor as temporary change of treatment may be necessary - You have a severe liver or kidney disorder If you are not sure if any of these apply to you, talk to your doctor or pharmacist before taking Daonil. Lowering of the haemoglobin level and breakdown of red blood cells (haemolytic anemia) can occur in patients missing the enzyme glucose-6-phosphate dehydrogenase. Epidemiological studies suggest an increased of cardiovascular mortality with administration of glibenclamide, when compared to metformin or gliclazide. The risk was especially observed in patients with diagnosed coronary (heart) diseases. Children The information available on the use of Daonil in people under 18 years of age is limited. Therefore Daonil is not recommended for use in children. Important information about hypoglycaemia (low blood sugar) When you take Daonil, you may get hypoglycaemia (low blood sugar). Please see below for additional information about hypoglycaemia, its signs and treatment. Following factors could increase the risk of you getting hypoglycaemia: - Undernourishment, irregular meal time, missed or delayed meal or period of fasting - Changes to your diet - Taking more Daonil than needed - Having kidneys that do not work properly - Having severe liver disease - If you suffer from particular hormone-induced disorders (disorders of the thyroid glands, of the pituitary gland or adrenal cortex) - Drinking alcohol (especially when you skip a meal) - Taking certain other medicines (see Other medicines and Daonil below) - If you increase the amount of exercise you do and you don’t eat enough food or eat food containing less carbohydrate than usual - If you are elderly or have adrenal or pituitary insufficiency Signs of hypoglycaemia include: - Hunger pangs, headache, nausea, vomiting, sluggishness, sleepiness, problems sleeping, restlessness, aggression, problems with concentration, reduced alertness and reaction time, depression, confusion, problems with your speech and sight, slurred speech, shakiness, partial paralysis, dizziness, helplessness - The following signs may also occur: sweating, clammy skin, anxiety, fast or increased heart beat, high blood pressure, awareness of your heart beat, sudden strong pain in the breast that may radiate into neighbouring areas (angina pectoris and cardiac arrhythmias). If blood sugar levels continue to drop you may suffer from considerable confusion (delirium), develop fits, lose self control, breathing may be shallow and your heart beat slowed down, you may fall into unconsciousness. The clinical picture of a severe reduced blood sugar level may resemble that of a stroke. Treating hypoglycaemia: In most cases the signs of reduced blood sugar vanish very quickly when you consume some form of sugar, e.g. sugar cubes, sweet juice, sweetened tea. You should therefore always take some form of sugar with you (e.g. sugar cubes). Remember that artificial sweeteners are not effective. Please contact your doctor or go to the hospital if taking sugar does not help or if the symptoms recur. Laboratory Tests The level of sugar in your blood or urine should be checked regularly. Your doctor may also take blood tests to monitor your blood cell levels and liver function. Other medicines and Daonil Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. Your doctor may wish to change your dose of Danoil if you are taking other medicines, which may weaken or strengthen the effect of Daonil on the level of sugar in your blood. The following medicines can increase the blood sugar lowering effect of Daonil. This can lead to a risk of hypoglycaemia (low blood sugar): - Other medicines to treat diabetes mellitus (such as insulin) - Medicines to treat pain and inflammation (phenylbutazone, azopropazone, oxyphenbutazone) - Medicines to treat urinary infections (such as some long acting sulfonamides) - Medicines to treat bacterial and fungal infections (tetracyclines, chloramphenicol, fluconazole, miconazole, quinolones, clarithromycin) - Medicines to inhibit blood clotting (coumarin derivatives such as warfarin) - Medicines supporting muscle build up (anabolics) - Medicines used for male sex hormone replacement therapy - Medicines to treat depression (fluoxetine, MAO-inhibitors) - Medicines lowering high cholesterol level (fibrates) - Medicines lowering high blood pressure (ACE inhibitors) - Medicines to treat gout (probenecid, sulfinpyrazone) - Medicines to treat cancer (cyclophosphamide, ifosfamide, trofosfamide) - Medicines used to reduce weight (fenfluramine) - Medicines to increase circulation when given in a high dose intravenous infusion (pentoxifylline) - Medicines to treat nasal allergies such as hay fever (tritoqualine) - Medicines called sympatholytics to treat high blood pressure, heart failure, or prostate symptoms The following medicines may decrease the blood sugar lowering effect of Daonil. This can lead to a risk of hyperglycaemia (high blood sugar level): - Medicines containing female sex hormones (oestrogens, progestogens) - Medicines to treat high blood pressure called thiazide diuretics (water tablets) - Medicines used to stimulate the thyroid gland - Medicines to treat allergies and inflammation (glucocorticoids) - Medicines to treat severe mental disorders (phenothiazine derivatives) - Medicines used to raise heart beat, to treat asthma or nasal congestion, coughs and colds, used to reduce weight, or used in lifethreatening emergencies (adrenaline and sympathomimetics) - Medicines to treat high cholesterol level (nicotinic acid) - Medicines to treat constipation when they are used long term (laxatives) - Medicines to treat fits (phenytoin) - Medicines to treat nervousness and sleep problems (barbiturates) - Medicines to treat increased pressure in the eye - Medicines to treat high blood pressure or lowering blood sugar (diazoxide) - Medicines to treat infections, tuberculosis (rifampicin) - Medicines to treat severe low blood sugar levels (glucagon) The following medicines can increase or decrease the blood sugar lowering effect of Daonil: - Medicines to treat stomach ulcers (called H2 antagonists) - Medicines to treat high blood pressure or heart failure such as beta-blockers, clonidine, guanethidine and reserpine. These can also hide the signs of hypoglycaemia, so special care is needed when taking these medicines Daonil may either increase or weaken the effects of the following medicines: - Medicines inhibiting blood clotting (coumarin derivatives such as warfarin) Taking Daonil with food and drink Alcohol intake may increase or decrease the blood sugar lowering action of Daonil in an unpredictable way. Pregnancy, breast-feeding and fertility Daonil should not be taken during pregnancy. Tell your doctor if you are, you think you might be or are planning to become pregnant. Daonil may pass into breast milk. Daonil should not be taken during breast feeding. Ask your doctor or pharmacist for advice before taking any medicine. Driving and using machines Your ability to concentrate or react may be reduced if your blood sugar is lowered (hypoglycaemia), or raised (hyperglycaemia) or if you develop visual problems as a result of such conditions. Bear in mind that you could endanger yourself or others (e.g. when driving a car or using machines). Please ask your doctor whether you can drive a car if you: - have frequent episodes of hypoglycaemia, - have fewer or no warning signals of hypoglycaemia Important information about some of the ingredients of Daonil Daonil contains lactose. If you have been told by your doctor that you cannot tolerate some sugars, contact your doctor before taking this medicinal product. HOW TO TAKE DAONIL Always take Daonil exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure. Taking this medicine - Take this medicine by mouth, just before or with the first main meal of the day (usually breakfast). If you do not have breakfast you should take the product on schedule as prescribed by your doctor. It is important not to leave out any meal when you are on Daonil. - Swallow the tablets whole with at least half glass of water. Do not crush or chew the tablets How much to take The dose of Daonil depends on your needs, condition and results of blood and urine sugar tests and is determined by your doctor. Do not take more tablets than your doctor has prescribed. - The usual starting dose is one 5mg tablet daily. - If necessary, your doctor may increase the dose after each 1 - 2 weeks of treatment. - If you are run down or are elderly, you will usually start by taking a lower dose. - Your dose of Daonil may need to be adjusted if you change weight, change your lifestyle, or if you are under a lot of stress. Please speak to your doctor if any of these situations apply to you. - If you feel the effect of your medicine is too weak or too strong do not change the dose yourself, but ask your doctor. If you take more Daonil than you should If you happen to have taken too much Daonil or an additional dose there is a danger of hypoglycaemia (signs of hypoglycaemia see Section 2 - Take special care with Daonil) and therefore you should instantly consume enough sugar (e.g. sugar cubes, sweet juice, sweetened tea) and inform a doctor immediately. When treating hypoglycaemia due to accidental intake in children, the quantity of sugar given must be carefully controlled to avoid the possibility of producing dangerous hyper-glycaemia. Persons in a state of unconsciousness must not be given food or drink. Since the state of hypoglycaemia may last for some time it is very important that the patient is carefully monitored until there is no more danger. Admission into hospital may be necessary, also as a measure of precaution. Show the doctor the package or remaining tablets, so the doctor knows what has been taken. Severe cases of hypoglycaemia accompanied by loss of consciousness and coma are cases of medical emergency requiring immediate medical treatment and admission into hospital. It may be helpful to tell your family and friends to call a doctor immediately if this happens to you. If you forget to take Daonil If you forget to take a dose, do not take a double dose to make up for forgotten doses. Take your normal dose as soon as you remember and continue as normal. If you are unsure or are concerned contact your doctor to discuss. If you stop taking Daonil If you interrupt or stop the treatment you should be aware that the desired blood sugar lowering effect is not achieved or that the disease will get worse again. Keep taking Daonil until your doctor tells you to stop. POSSIBLE SIDE EFFECTS Like all medicines, Daonil can cause side effects, although not everybody gets them. Tell your doctor immediately if you experience any of the following symptoms: - Allergic (hypersensitivity) reactions which may include - Swelling of the lips, face, throat or tongue - Skin rash, itching, hives and increased sensitivity to the sun - Inflammation of blood vessels, often accompanied with skin rash, which may develop into serious reactions accompanied with difficulty breathing, fall in blood pressure and sometimes progressing to shock - Abnormal liver function including yellowing of the skin and eyes (jaundice), problems with the bile flow (cholestasis), inflammation of the liver (hepatitis) or liver failure. - Severe hypoglycaemia including loss of consciousness, seizures or coma Rare: may affect up to 1 in 1,000 people - Lower blood sugar than normal (hypoglycaemia) (See Section 2 - Take special care with Daonil) - Decrease in the number of blood cells: - Blood platelets (which increases risk of bleeding or bruising) - White blood cells (which makes infections more likely) - Red blood cells (which can make the skin pale and cause weakness or breathlessness) These problems generally get better after you stop taking Daonil. Very rare: may affect up to 1 in 10,000 people - Feeling or being sick, diarrhoea, feeling full or bloated and abdominal pain - Decrease in the amount of sodium level in your blood (shown by blood tests) - Problems with your sight may occur when beginning treatment with Daonil. This is due to changes in blood sugar levels and should soon improve - Increased liver enzymes Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via HPRA Pharmacovigilance Earlsfort Terrace IRL - Dublin 2 Website: www.hpra.ie E-mail: medsafety@hpra.ie By reporting side effects you can help provide more information on the safety of this medicine. HOW TO STORE DAONIL Keep this medicine out of the sight and reach of children. Do not use Daonil Tablets after the expiry date which is stated after 'EXP' on the blister and carton. The expiry date refers to the last day of that month. Do not store above 25°C. Store in the original package to protect from light. Do not throw away any medicines via waste water or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment. CONTENTS OF THE PACK AND OTHER INFORMATION What Daonil contains The active substance is glibenclamide. Daonil 5mg Tablets contain 5mg of glibenclamide. Other ingredients include lactose monohydrate, maize starch, pregelatinised maize starch, talc, colloidal anhydrous silica and magnesium stearate. What Daonil looks like and contents of the pack Daonil 5mg Tablets are white oblong shaped tablets. LDI is engraved on each side of the score-line and inverted. The other face is plain. The score-line allows the tablets to be divided into equal halves. Daonil 5mg Tablets are available in carton packs of 100 tablets. Marketing Authorisation Holder and Manufacturer Marketing Authorisation Holder: sanofi-aventis Ireland Ltd., T/A SANOFI Citywest Business Campus Dublin 24 Email: IEmedinfo@sanofi.com Manufacturer: Sanofi-Winthrop Industrie 56 Route de Choisy au bac 60205 Compiegne France Sanofi-Aventis Deutschland GmbH Industriepark Hochst D-65926 Frankfurt am Main Germany Famar L’Aigle Z.I. No.1, Route de Crulai 61300 L’Aigle France This leaflet was revised in April 2015.
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Euthyrox 50- uputa: kako uzimati, nuspojave, čuvanje… U ovoj uputi: - Što je Euthyrox i za što se koristi - Prije nego počnete uzimati Euthyrox - Kako uzimati Euthyrox - Moguće nuspojave - Kako čuvati Euthyrox - Dodatne informacije Cijena pakiranja Euthyrox 50 je 20.65 kuna. ŠTO JE EUTHYROX I ZA ŠTO SE KORISTI Levotiroksin, djelatna tvar Euthyroxa, je sintetski hormon štitne žlijezde za liječenje bolesti i poremećaja rada štitne žlijezde. Ima jednaki učinak kao i prirodni hormon štitne žlijezde. Euthyrox se koristi - za liječenje benigne eutiroidne gušavosti kod bolesnika s normalnom funkcijom štitne žlijezde; - za sprečavanje ponovne pojave gušavosti nakon operacije; - kao nadomjestak prirodnog hormona štitne žlijezde, kada ga Vaša štitne žlijezde ne proizvodi dovoljno; - za potiskivanje ponovne pojave tumora kod bolesnika s karcinomom štitne žlijezde; Euthyrox 50 mikrograma tablete upotrebljavaju se još za uspostavljanje ravnoteže hormona štitne žlijezde kada se pojačano lučenje hormona liječi antitireoidnim lijekovima. PRIJE NEGO POČNETE UZIMATI EUTHYROX Euthyrox nemojte uzeti ukoliko se neko od sljedećih stanja odnosi na Vas: - alergija (preosjetljivost) na djelatnu tvar ili bilo koji od drugih sastojaka Euthyroxa (pogledajte poglavlje 6); - neliječeni poremećaj nadbubrežne žlijezde, hipofize ili pojačano lučenje hormona štitne žlijezde (tireotoksikoza); - akutna bolest srca (infarkt miokarda ili upala srca). Ako ste trudnica, Euthyrox nemojte uzimati zajedno s antitireoidnim lijekovima (pogledajte poglavlje Trudnoća dojenje). Budite oprezni s Euthyroxom ako imate neku od sljedećih bolesti: - nedovoljan protok krvi u krvnim žilama srca (angina pektoris); zatajenje srca; - ubrzan i nepravilan rad srca; - visoki krvni tlak; - stvaranje masnih naslaga u krvnim žilama (arterioskleroza). Prije početka uzimanja Euthyroxa, ili prije supresijskog testa štitne žlijezde, ova stanja moraju biti pod liječničkim nadzorom. Tijekom uzimanja Euthyroxa, razinu Vaših hormona štitne žlijezde morate često kontrolirati. Ako niste sigurni da li se neko od ovih stanja odnosi na Vas, ili ako se ne liječite, razgovarajte sa svojim liječnikom. Vaš liječnik će provjeriti da lj imate poremećaj rada nadbubrežne žlijezde ili hipofize ili poremećaj rada štitne žlijezde uz nekontroliranu prekomjernu produkciju hormona štitne žlijezde (tiroidna autonomija), budući da prije početka uzimanja Euthyroxa, ili prije supresijskog testa štitne žlijezde, ova stanja moraju biti pod liječničkim nadzorom. Razgovarajte sa svojim liječnikom - ako ste u menopauzi ili postmenopauzi; Vaš liječnik će možda trebati redovno provjeravati funkciju Vaše štitne žlijezde radi rizika od osteoporoze, - ako prelazite s jednog na drugi lijek koji sadržava levotiroksin. Učinak se može blago razlikovati te može biti potrebno pažljivije praćenje i prilagodba doze. Uzimanje s drugih lijekova s Euthyroxom Obavijestite svog liječnika ako uzimate neki od sljedećih lijekova jer Euthyrox može imati utjecaj na njihov učinak: - antidijabetici (lijekovi za snižavanje šećera u krvi): Euthyrox može umanjiti učinak antidijabetika te ćete možda trebati dodatne kontrole razine šećera u krvi, naročito na početku liječenja Euthyroxom.tijekom uzimanja Euthyroxa, može biti potrebna prilagodba doze Vašeg antidijabetika. - derivati kumarina (lijekovi koji sprečavaju zgrušavanje krvi): Levotiroksin može pojačati učinak ovih lijekova te ćete možda trebati redovne kontrole vrijednosti zgrušavanja, naročito na početku liječenja. Tijekom uzimanja Euthyroxa može biti potrebna prilagodba doze kumarina. Pazite na pridržavanje preporučenih vremenskih razmaka, ako uzimate neki od sljedećih lijekova: - lijekovi koji snižavaju razinu masnoće u krvi i visoki kolesterol (kao što su kolestiramin i kolestipol): Pazite da Euthyrox uzmete 4-5 sati prije ovih lijekova jer oni mogu blokirati preuzimanje Euthyroxa iz crijeva. - antacidi (za ublažavanje simptoma žgaravice), sukralfati (za čir želuca ili crijeva), drugi lijekovi koji sadržavaju aluminij, željezo ili kalcijev karbonat Pazite da Euthyrox uzimate barem 2 sata prije uzimanja ovih lijekova jer u suprotnom mogu umanjiti njegov učinak. Obavijestite svog liječnika ako uzimate sljedeće lijekove jer mogu umanjiti učinak Euthyroxa: - propiltiouracil (antitiroidni lijek); - glukokortikoidi (antialergijski i protuupalni lijekovi); - beta-blokatori (lijekovi koji smanjuju krvni tlak i primjenjuju se za liječenje bolesti srca); - sertralin (antidepresiv); - klorokin ili progvanil (lijekovi protiv malarije); - lijekovi koji aktiviraju neke enzime jetre kao što su barbiturati (sedativi, tablete za spavanje), - lijekovi koji sadržavaju estrogen, a koji se primjenjuju kao hormonska nadomjesna terapija tijekom ili nakon menopauze ili za sprečavanje trudnoće. Obavijestite svog liječnika ako uzimate neki od sljedećih lijekova jer mogu pojačati djelovanje Euthyroxa: - salicilati (lijekovi koji se primjenjuju za ublažavanje boli i sniženje tjelesne temperature); dikumarol (lijek za sprečavanje zgrušavanja krvi); - furosemid u visokim dozama od 250 mg (diuretik); - klofibrat (lijekovi za snižavanje lipida u krvi); - fenitoin (antiepileptik). Obavijestite svog liječnika ako uzimate amiodaron (lijek koji se primjenjuje za liječenje nepravilnog ritma srca) jer ovaj lijek može imati utjecaj na aktivnost Vaše štitne žlijezde. Ako trebate biti podvrgnuti dijagnostičkim testovima ili snimanju koji uključuju kontrastna sredstava koji sadržavaju jod, recite svom liječniku da uzimate Euthyrox jer ćete možda primiti injekciju koja može imati utjecaj na rad Vaše štitne žlijezde. Obavijestite svog liječnika ako uzimate ili ste nedavno uzimali bilo kakve lijekove, uključujući one koje kupujete bez recepta. Hormoni štitne žlijezde nisu prikladni za sniženje tjelesne težine. Uzimanje hormona štitne žlijezde neće umanjiti Vašu tjelesnu težinu, ako su Vaši hormoni štitne žlijezde na normalnoj razini. Ako povećate dozu bez da Vam je to posebno savjetovao liječnik, mogu se pojaviti teške, pa čak I po život opasne nuspojave. Uzimanje hrane i pića s Euthyroxom Recite svom liječniku ako jedete hranu koja sadržava soju, naročito ako mijenjate količine koje jedete. Proizvodi od soje mogu umanjiti apsorpciju Euthyroxa iz crijeva te stoga može biti potrebna prilagodba doze Euthyroxa. Trudnoća i dojenje Ako ste trudnica, nastavite uzimati Euthyrox. Razgovarajte sa svojim liječnikom, radi moguće prikgoa Ako Euthyrox uzimate zajedno s antitireoidnim lijekovima za liječenje prekomjernog lučenja hormona štitne žlijezde, Vaš liječnik će Vam savjetovati da tijekom trudnoće prekinete uzimati Euthyrox. Ako dojite, nastavite s uzimanjem Euthyroxa u skladu s preporukama Vašeg liječnika. Količina ovog lijeka koja se izlučuje u majčino mlijeko je tako mala da neće imati nikakav učinak na dijete. Upravljanje vozilima i strojevima Studije djelovanja levotiroksina na sposobnost upravljanja vozilima i strojevima nisu provođene. Međutim, budući da je levotiroksin identičan prirodnim hormonu štitne žlijezde, ne očekuje se da bi Euthyrox imao utjecaj na sposobnost upravljanja vozilima ili strojevima. Važne obavijesti o nekim sastojcima Euthyroxa Ako Vam je liječnik rekao da imate bolest nepodnošenja nekih šećera, prije nego što počnete uzimati ovaj lijek posavjetujte se sa svojim liječnikom jer Euthyrox sadržava laktozu. KAKO UZIMATI EUTHYROX Euthyrox uvijek uzimajte onako kako Vam je propisao Vaš liječnik. Individualnu dnevnu dozu određuje liječnik na temelju dijagnostičkih laboratorijskih testova i kliničkog pregleda. U pravilu, liječenje ćete započeti niskom dozom koja se povećava svaka 2-4 tjedna, do postizanja Vaše pune, individualne doze.Tijekom početnih tjedana napravit ćete laboratorijske kontrole, radi prilagodbe doze. Uobičajeno doziranje prikazano je u donjoj tablici. Niže individualne doze mogu biti dovoljne: - ako ste starija osoba, - ako imate srčane probleme, - ako imate teške ili dugotrajne probleme oslabljene funkcije štitne žlijezde, - ako ste niske tjelesne težine ili s velikom strumom. Primjena Euthyroxa - za liječenje benigne gušavosti uz normalnu funkciju štitne žlijezde » 75-200 mikrograma dnevno - sprečavanje povrata gušavosti nakon operacije » 75-200 mikrograma dnevno - nadomještaj prirodnih hormona štitne žlijezde kada ih Vaša štitna žlijezda ne producira dovoljno: - odrasli: početna doza » 25- 50 mg, doza održavanja » 100- 200 mikrograma - djeca: početna doza » 12.5- 50 mg, doza održavanja » 100- 150 mikrograma - supresija rasta tumora kod bolesnika s karcinomom štitne žlijezde » 150 do 300 mikrograma - uspostavljanje ravnoteže hormona štitne žlijezde kada se prekomjerno lučenje hormona liječi antitiroidnim lijekovima » 50 do 100 mikrograma Primjena Euthyrox je namijenjen za primjenu kroz usta. Uzmite čitavu dnevnu dozu ujutro na prazan želudac, (najmanje pola sata prije doručka), najbolje s nešto tekućine, npr. pola čaše vode. Djeci se daje čitava dnevna doza najmanje pola sata prije prvog obroka u danu. Neposredno prije davanja, razmrvite tabletu, pomiješajte s malo vode i dajte je djetetu s još nešto više vode. Ovu smjesu uvijek pripremite svježu. Trajanje liječenja Trajanje liječenja ovisi o stanju radi kojeg uzimate Euthyrox. O tome koliko dugo trebate uzimati Flithyrnx razgovarati ćete sa svojim liječnikom. Većina bolesnika Euthyrox uzima tijekom čitavog života. Ako uzmete više Euthyroxa nego što ste trebali Ako uzmete više Euthyroxa nego što ste trebali, možete osjetiti simptome kao što su ubrzani otkucaji srca, anksioznost, uznemirenost i nehotične kretnje. Ako se ovo dogodi, molimo obratite se svom liječniku. Ako ste zaboravili uzeti Euthyrox Ne uzimajte dvostruku dozu da biste nadoknadili zaboravljenu tabletu, nego sljedećeg dana uzmite normalnu dozu.. U slučaju bilo kakvih nejasnoća ili pitanja u vezi s primjenom Euthyroxa, obratite se svom liječniku ili ljekarniku. MOGUĆE NUSPOJAVE Kao i svi drugi lijekovi, i Euthyrox može izazvati nuspojave, ali one se ne pojavljuju kod svih osoba. Euthyrox je identičan prirodnom hormonu štitne žlijezde. Stoga, ako uzimate propisanu,dozu Euthyroxa i redovno obavljate laboratorijske kontrole u skladu s uputama Vašeg liječnika, nuspojave se ne očekuju. Ako ste uzeli više Euthyroxa nego što je propisano, ili ako ne podnosite određenu dozu (npr. kod prebrzog povećanja doze) možete osjetiti jednu ili više od sljedećih nuspojava: Nepravilne ili ubrzane otkucaje srca, bol u grudima, glavobolju, slabost mišića i grčeve, iznenadno crvenilo (žarenje i crvenilo lica), vrućicu, povraćanje, menstrualne poremećaje, pseudotumor mozga (povećani pritisak u glavi uz oticanje očiju), drhtavicu, nemir, nesanicu, pojačano znojenje, gubitak tjelesne težine i proljev. Ako primijetite bilo koju navedenu nuspojavu, obratite se svom liječniku. Vaš liječnik će odlučiti treba li prekinutu terapiju na nekoliko dana ili smanjiti dnevnu dozu do povlačenja nuspojave. Moguće su alergijske reakcije na neki od sastojaka Euthyroxa (pogledajte poglavlje 6. „Što Euthyrox 50 mikrograma sadrži”). Ako se ovo dogodi, odmah se javite svom liječniku. Ako primijetite bilo kakvu nuspojavu potrebno je obavijestiti liječnika ljekarnika. KAKO ČUVATI EUTHYROX Euthyrox morate čuvati izvan dohvata i pogleda djece. Euthyrox se ne smije primjenjivati nakon isteka roka valjanosti označenog na pakovanju. Istek roka valjanosti odnosi se na zadnji dan navedenog mjeseca. Euthyrox čuvajte na temperaturi do 25 °C. Blistere čuvajte u zatvorenoj kutiji, radi zaštite lijeka od svjetlosti. Lijekovi se ne smiju odbacivati u odvod ili kućno smeće. Pitajte svog ljekarnika kako odložiti lijek koji više ne trebate. Ove mjere pridonose zaštiti okoliša. OSTALE INFORMACIJE Što Euthyrox 50 mikrograma sadrži Djelatna tvar Euthyrox tableta je levotiroksin. Svaka tableta sadržava 50 mikrograma levotiroksinnatrija. Ostale tvari su kukuruzni škrob; kannelozanatrij, umrežena; želatina; laktoza hidrat i magnezijev stearat. Kako Euthyrox 50 mikrograma izgleda i sadržaj pakovanja Euthyrox 50 mikrograma su bijele, okrugle tablete, ravne s obje strane, zakošenog ruba, s razdjelnim urezom natpisom EM 50 na površini. Euthyrox je raspoloživ u pakovanjima od 90 (3×30) i 100 (4×25) tableta. Napomena: Ovo su neslužbene i skraćene upute. Za službene upute obratite se ljekarniku ili proizvođaču.