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Millions of people are increasing their risk of a heart attack by taking painkillers, research reveals. Experts say there is an added danger even within the first week of taking non-steroidal anti-inflammatory drugs, such as ibuprofen and naproxen. The highest risk was found to be in the first month of taking the pills and to those on a high daily dose – such as more than 1,200mg of ibuprofen, 750mg of naproxen and 25mg rofecoxib. Researchers from Canada, Finland and Germany analysed data on 450,000 people, including 61,460 who had suffered a heart attack, and urged doctors to consider the risks before giving the commonly prescribed drugs. Almost 15 million NSAIDs were prescribed in England last year and annual sales are worth billions. The team’s study, published in The BMJ medical journal, found using the drugs for longer than one month did not increase risk more than with shorter use. It also found the overall risk of a heart attack if taking celecoxib, ibuprofen, diclofenac, naproxen and rofecoxib rose between 24% and 58%, compared with not using these drugs. The authors said: “Given that the onset of risk of acute myocardial infarction [heart attack]occurred in the first week and appeared greatest in the first month of treatment with higher doses, prescribers should consider the risks and benefits of NSAID.” Dr Mike Knapton, of the British Heart Foundation , was alarmed by how quickly the risk set in. He said: “Whether you’re prescribed painkillers like ibuprofen, or buy them, people must be made aware of the risk and alternative medication should be considered.”
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Lijek koji svi kupujemo bez recepta drastično povećava rizik od srčanog udara! buprofen, lijek koji je i kod nas vrlo raširen kao nesteroidni protuupalni analgetik, drastično povećava rizik od srčanog udara i to unutar prvih sedam dana redovnog korištenja. Tim međunarodnih naučnika radio je na istraživanju koje je pokazalo kako je ukupni rizik od srčanog udara u dužem razdoblju i dalje nizak, ali kako je najizgledniji u prvom mjesecu, čak i prvoj sedmici redovnog uzimanja ovog lijeka. Istraživanje je objavljeno u časopisu British Medical Journal, a napravljeno je na osnovu 450.000 osoba od kojih je 61.460 osoba pretrpjelo infarkt. U sklopu istraživanja proučavano je pet analgetika, a pokazalo se kako oni, u zavisnosti o kojem se radi, povećavaju rizik od srčanog udara za između 24 i 58 posto. Iapk, bitno je reći kako je i najmanje povećanje rizika od infarkta vrlo važno u kontekstu javnog zdravlja budući da su, posebno ibuprofeni, vrlo često korišteni. Iako se ovaj lijek može dobiti u apotekama bez recepta, ipak bi se u slučaju dužeg korištenja trebalo posavjetovati s lijekarom. (avaz)