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Alzheimer's disease health centre Fish oils may delay brain ageing 22nd January 2014 – Fish oils may delay the loss of brain cells as we age by 1 to 2 years, according to a study published in the online issue of the US medical journal Neurology. Shrinking brain volume is a sign of Alzheimer’s disease as well as normal ageing. The newly published study found that women with higher levels of the omega-3 fatty acids found in fish oil may also have larger brain volumes in old age, equivalent to preserving 1 to 2 years of brain health. The study Omega-3 fatty acids can be found in fish such as trout, mackerel, sardines and salmon. You can also get fish oil capsules over the counter from pharmacies, health food shops or supermarkets. For the study, the levels of omega-3 fatty acids in red blood cells were tested in 1,111 older women who were part of the Women’s Health Initiative Memory Study in the US. Eight years later, when the women were an average age of 78, MRI scans were taken to measure their brain volume. Those with higher levels of omega-3s had larger total brain volumes. They also had a 2.7% larger volume in the hippocampus area of the brain, which plays an important role in memory. According to a statement by study author Dr James Pottala, of the University of South Dakota: "These higher levels of fatty acids can be achieved through diet and the use of supplements, and the results suggest that the effect on brain volume is the equivalent of delaying the normal loss of brain cells that comes with ageing by 1 to 2 years." Alzheimer's disease Commenting on the study, Dr Doug Brown, director of research and development at the Alzheimer’s Society says: "It’s interesting to see that eating more fish could lead to larger brain volume, particularly in the hippocampus – an area of the brain that comes under attack in dementia. We know that brain shrinkage can be linked to dementia and larger brain volumes could indicate a better ability to cope with the ravages of the condition, but it’s a big leap to draw this conclusion." He says: "Whilst interesting, this study still leaves us in the dark about what effect eating fish has on the development of dementia specifically." Previous research A study of more than 2,000 older women published last September found that a diet rich in omega-3 fatty acids 'may not protect against brain ageing'. Dr Laura Phipps of Alzheimer’s Research UK comments by email: "There has been mixed evidence as to the benefits of omega-3 fish oils on the brain and whether they may protect against memory decline and dementia. This study suggests that higher levels of omega-3 fatty acids in blood are linked to larger brain size but the possible reasons for this association need further investigation. We know that the brain gets smaller in people with dementia, but it is unclear from the study what effect larger brain size would have on memory and thinking in the volunteers or their long-term risk of developing dementia. "The best way to assess whether omega-3 could protect against dementia is through clinical trials and so far, trials of omega-3 supplementation have not shown benefits in protecting against cognitive decline. Currently, research suggests that a balanced diet, along with regular exercise, not smoking, maintaining a healthy weight and keeping blood pressure and cholesterol in check may help to keep our brains healthy as we get older." Today in Alzheimer's disease Mind, body & soul newsletter health and wellbeing.
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Znanstvenici iz Rhode Island Hospital su u novoj studiji još jednom potvrdili važnost omega-3 masnih kiselina. Pokazalo se da svakodnevni unos ovih masnih kiselina ima poveznicu s usporavanjem slabljenja kognitivnih sposobnosti kod osoba starije životne dobi. Rezultati su objavljeni u stručnom časopisu Alzheimer’s & Dementia, a ispitane su sposobnosti kod 819 sudionika uz pomoć standardiziranih testova koji su tijekom 4 godine bili podvrgavani redovnim pregledima mozga NMR uređajem. Utvrđeno je kako svakodnevni unos omega-3 masnih kiselina ima ulogu u usporavanju procesa atrofije mozga kod starijih osoba. To usporavanje je najizraženije u cerebralnom korteksu i hipokampusu, dijelovima mozga koji su ključni za formiranje i zadržavanje pamćenja. Zato se preporučuje barem 2 puta tjedno jesti ribu, jer je glavni izvor omega-3 masnih kiselina upravo riba.