http___www.tportal.hr_lifestyle_zdravlje_60812_Uskoro-pilula-protiv-menstrualnih-bolova.html_1.xml
1.1 1.2 2.1 3.1 3.2 3.3 3.4 3.5 4.1 4.2 4.3 5.1 5.2 5.3 6.1 7.1 7.2
An experimental new drug can ease menstrual cramps by targeting the cause rather than the symptom of the pain, says the scientists. The newly developed drug is now known by the code name VAIII913. Buzz up! Menstrual cramps, also known as dysmenorrhea, creates several problems which include the pain in abdomen and back, nausea, mood swings, vomiting, sweating, and dizziness for ninety percent of the women. Menstrual cramps are caused by contractions of the uterus during menstruation. In dysmenorrhea, the uterus contracts with increased frequency, causing unusually severe, cramping pain. The reason for this is the increased blood levels of the hormone Vasopressin, which plays a role in regulating contraction of the uterus. The newly developed drug helps blocking the hormones, which can relieve dysmenorrhea. Existing treatments for the condition include pain-relievers, anti-inflammatory drugs, and oral contraceptives that stop menstruation. These treatments are ineffective in almost one-third of women with moderate to severe cases. Some of them relieve only the symptoms, rather than targeting the underlying cause of dysmenorrhea, and may have unwanted side effects such as mood alteration and stomach upsets. The newly developed drug, VAIII913, can fine tune the effects of dysmenorrhea. This drug is to be administered orally as a pill, rather than an injection. The drug is safe, with no apparent ill effects. The next phase of clinical trials is currently underway in the U.K. and the U.S. to evaluate how well it works to control pain in a group of women with dysmenorrhea. Investigators expect results to be available later this year. If studies continue to show promise, the drug could be available to patients in four years, says the scientists.
1.1 2.1 2.2 3.1 3.2 3.3 4.1 4.2 5.1 5.2 6.1 6.2 8.1
Lijek koji bi trebao milijune žena konačno riješiti menstrualnih grčeva i bolova mogao bi se uskoro naći na tržištu Pilula je stvorena s ciljem da se bori s bolnim menstrualnim grčevima (dismenoreja) koji muče 90 posto mladih i sredovječnih žena svakog mjeseca. Uzima li se uoči menstruacije, može u potpunosti odagnati bol, no može se koristiti i kad bol nastupi i u tom slučaju ga učinkovito ublažava. Uobičajeni PMS simptomi uključuju bolove u trbuhu i leđima, mučninu, povraćanje, znojenje i vrtoglavicu. Postojeće metode liječenja za to stanje uključuju analgetike, protuupalne lijekove i oralnu kontracepciju koja zaustavlja menstruaciju. Međutim, sve te metode liječenja su zapravo neučinkovite kod više od trećine žena s umjerenim i ozbiljnim slučajevima PMS-a. Većina tih lijekova ublažava simptome, a ne bavi se njihovim uzrocima. Menstrualne grčeve uzrokuju kontrakcije maternice za vrijeme menstruacija, a kod dismenoreje maternica kontaktira povećanim intenzitetom, što uzrokuje ozbiljne i bolne grčeve. Znanstvenici vjeruju da je uzrok povećana razina hormona vazopresina u krvi koji igra značajnu ulogu u regulaciji kontrakcija maternice. U farmaceutskoj tvrtki Vantia došli su do otkrića da blokiranje tog hormona može pomoći u ublažavanju dismenoreje, a lijek na kojem trenutno rade na tržištu bi se mogao naći za četiri godine. - Sviđa vam se članak? Preporučite ga prijateljima putem ovih servisa: Pošaljite mailom