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Double mastectomy choice challenged by researchers Nearly three-quarters of women who have both breasts removed after a cancer diagnosis may be wrong to take the drastic step, a study has suggested. Researchers who studied 1,447 women treated for breast cancer found that 8% of them had undergone a double mastectomy. But 70% of these women did not meet the medically approved criteria for losing both breasts – a family history of breast or ovarian cancer, or BRCA 1 or BRCA 2 gene mutations. “Having a non-affected breast removed will not reduce the risk of recurrence in the affected breast” Sarah Hawley They had a very low risk of developing cancer in the healthy breast, the US scientists said. Study leader Dr Sarah Hawley, from the University of Michigan, said: “Women appear to be using worry over cancer recurrence to choose contralateral prophylactic mastectomy. “This does not make sense, because having a non-affected breast removed will not reduce the risk of recurrence in the affected breast,” she said. “For women who do not have a strong family history or a genetic finding, we would argue it’s probably not appropriate to get the unaffected breast removed.” The research, published in the journal JAMA Surgery, also found that 18% of the women studied had considered a double mastectomy. Women with a risky family history and BRCA mutations make up around 10% of all those diagnosed with breast cancer. They are considered to be at high risk of a new cancer developing in the unaffected breast. Without these indications, women who develop a tumour in one breast are very unlikely to acquire a second cancer in the other. Many of the women in the study who elected to have a double mastectomy were candidates for breast-conserving surgery to remove lumps, the researchers said. Overall, about three-quarters of the patients reported being very worried about their cancer. Those who chose to have both breasts removed were significantly more likely to be concerned. A double mastectomy is a major operation that can be associated with complications and difficult recovery, the authors pointed out. Most of the participants who had the procedure underwent breast reconstruction as well. The study found that women with higher education levels and who had been given a magnetic resonance imaging (MRI) scan before surgery were more likely to choose a double mastectomy. The new research coincides with former Dancing With The Stars host Samantha Harris making public her decision to have a double mastectomy following a diagnosis of breast cancer. She was praised by Baroness Delyth Morgan, chief executive of the Breast Cancer Campaign, who said: “Samantha’s openness in sharing her experience serves as a stark reminder of the impact of a breast cancer diagnosis. “Being breast aware can be crucial to early diagnosis, increasing chances of survival. It is important women report any unusual changes to their GP and consider attending routine breast screening when invited.” Ms Harris discovered a lump in her right breast during a routine self-examination. Readers' comments (1) I had breast cancer with a mastectomy and tram flap reconstruction in one breast. I was told I had a 93% chance of not having a recurrence. 19 years later I was diagnosed with a completely different type of cancer in the other breast and ended up with a mastectomy. This past year has been difficult and trying with needing chemotherapy, surgery and then radiation however, I can not say that I am sorry that I did not have a double mastectomy when I had the first cancer. I lived 19 years with my own breast on the unaffected side. It was not recommended at that time and I know that having a double mastectomy is not as easy as it sounds. Surgery is surgery and has its own recovery and possible complications. It should not be taken lightly and I don't think it should be recommended to everyone. Have your say You must sign in to make a comment.
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Žene koje su se podvrgnule dvostrukoj mastektomiji zbog straha da bi mogle razviti karcinom možda nisu poboljšale svoje šanse za preživljavanje, pokazala je najnovija studija Sveučilišta u Minnesoti Štoviše, čini se da je čak četiri od pet preventivnih mastektomija napravljeno nepotrebno, što je zanimljiv podatak u svjetlu statistike koja govori da se u posljednjih deset godina broj dvostrukih mastektomija udvostručio. Studija koju prenosi Slobodna Dalmacija je, naime, pokazala da je očekivano trajanje preživljavanja žena koje su se podvrgnule tom zahvatu bilo za šest mjeseci dulje neovisno o drugim rizičnim faktorima kao što je dob pacijentice i stadij karcinoma. Početkom ove godine slavna glumica Angelina Jolie podvrgnula se dvostrukoj mastektomiji nakon što joj je rečeno da ima 87 postotnu šansu da će razviti karcinom dojke budući da ima pozitivne testove na mutirani gen BRCA 1, ali i obiteljsko naslijeđe. Naime, Angelinina majka, baka po majčinoj liniji i tetka umrle su od karcinoma dojke odnosno jajnika u svojim kasnim 40-im i 50-im godinama. No žene poput holivudske zvijezde koje se podvrgavaju preventivnoj mastektomiji zbog straha od karcinoma, a ne zbog realnih indikacija možda ipak neće povećati svoje šanse za preživljavanje, pokazalo je istraživanje, budući da dvostruka mastektomija smanjuje rizik za razvoj karcinoma na drugoj dojci za manje od pet posto. Za čak četiri od pet preventivnih mastektomija nisu postojali opravdani razlozi. Najnovija studija čiji su rezultati objavljeni na kliničkom kongresu (Clinical Congress of the American College of Surgeons) analizirala je način na koji su žene donosile odluku. Pokazalo se da se većina žena s otkrivenim karcinomom dojke u ranoj fazi u jednoj dojci odlučivala za puno agresivniji zahvat uklanjajući obje dojke. Ta vijest došla je samo tjedan dana nakon što je eminentni britanski kirurg prof. Kefah Mokbel s London Breast Institutea upozorio da su dvostruke mastektomije besmislene kod žena koje nisu u istoj kategoriji kao Jolie. Učestalost dvostrukih mastektomija više se nego udvostručila u posljednjih deset godina kod žena s ranim stadijem karcinoma u jednoj dojci, iako se čini da taj zahvat neće značajno povećati preživljavanje. Naime, znanstvenici tvrde da je rizik razvoja karcinoma u drugoj dojci vrlo nizak. U visokom su riziku žene koje imaju pozitivno obiteljsko naslijeđe (rak dojke ili jajnika kod najbližih srodnika) i one koje su pozitivne na mutaciju gena BRCA1 i BRCA2. - Sviđa vam se članak? Preporučite ga prijateljima putem ovih servisa: Pošaljite mailom