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What is celiac disease? What is Dermatitis Herpetiformis? What are HLA DQ2 and DQ8? What are the symptoms? How do you get tested? What are the blood tests I should get? Is testing the same for Dermatitis Herpetisformis? What is the difference between Celiac Disease and Gluten Intolerance? If I have some of the symptoms, should I try going on the gluten free diet? I have just been diagnosed with celiac disease, should I get my family tested too? What is gluten and the gluten free diet? If I have celiac disease, do I have to follow the gluten free diet forever? What is the Kogan Celiac Center? Where is the Kogan Celiac Center located? How does the program work? Are there support groups for people with celiac disease? How do the recent changes in labeling laws affect someone following the gluten free diet? What about alcohol? Celiac disease is a lifelong, genetic intolerance to certain proteins found in the grains wheat, barley and rye. When ingested by an individual with celiac disease, these proteins trigger an autoimmune inflammatory response in the small intestine, causing damage to the absorptive structures called villi. When villi are damaged, their ability to absorb nutrients (fat, carbohydrate, protein, vitamins and minerals) is greatly reduced, resulting in compromised nutritional status and increased risk for diseases of almost every organ system. In fact, the word “celiac” comes from the Greek word “Koiliakos,” which means “abdomen” or “hollow” and refers to the way an individual with celiac disease can eat but remain malnourished when gluten is present in the diet. Although most experts agree that individuals with certain genes can get celiac disease at some point in their lives (see discussion about HLA DQ2 and DQ8 below), it is not yet understood what triggers the onset of the disease or when it actually happens. Some research suggests the following may have an effect: early introduction of gluten-containing foods to a baby’s diet, puberty, the stress of surgery, illness or pregnancy, or a stressful occurrence in one’s life. Presently, there is no cure for the 1 in 133 individuals who are believed to have celiac disease in the United States, and the only known treatment is lifelong adherence to a gluten free diet. At the Kogan Celiac Center, we are committed to early diagnosis and a comprehensive, multidisciplinary approach to treating and managing this disease for our adult and pediatric patients. top ] This is an itchy, blistering skin condition that is associated with celiac disease. It is commonly found bilaterally on the buttocks, knees, elbows, face and scalp. Individuals with the diagnosis of Dermatitis Herpetiformis can also show similar damage to the small bowel and show positive response to the gluten free diet. top ] HLA (Human Leukocyte Antigen) is a genetic marker or “flag” that exists on the surface of each cell in our bodies. Its function is to help the immune system distinguish between “self” cells and “invader” cells. Individuals who have either HLA DQ2 or HLA DQ8 markers are at risk for developing celiac disease and the presence or absence of this genetic material can be useful information in diagnosing this disease. top ] Symptoms of celiac disease may include any of the following: diarrhea, change in bowel habits, abdominal bloating, failure to thrive, delayed weight gain and/or growth retardation, skin rash, discolored teeth, depression, irritability, fatigue, anemia, missed menstrual periods or joint pain. Some conditions associated with untreated celiac disease are osteoporosis, Vitamin K deficiency, intestinal lymphoma, dental enamel defects, infertility and/or miscarriage and general malnutrition. top ] Initially, a blood test is ordered to determine if antibodies against gluten are being produced. High levels of antibodies show increased immune reaction and a strong likelihood for celiac disease. This suspicion is confirmed by examining the villi via a small bowel biopsy - a short, minimally invasive procedure usually done on an out-patient basis. top ] The Kogan Celiac Center follows a strict protocol to measure the specific antibodies that are markers for celiac disease. Of the most sensitive and specific tests, IgA tissue transglutaminase (tTG) antibody testing is ordered, or IgG tissue transglutaminase antibody testing when individuals are deficient in IgA responses. Screenings that use these tests are hosted frequently by the Kogan Celiac Center. top ] No, a skin biopsy is used to diagnose this skin condition. top ] Celiac disease is characterized by an autoimmune reaction to gluten in genetically susceptible individuals that results in intestinal damage and malnutrition that can affect any organ system in the body. The only known treatment for celiac disease is a very strict, lifelong compliance with a gluten free diet. Gluten intolerance, for the most part, results in GI distress in individuals who consume gluten, without autoimmune or malabsorption results. It is not known yet if there is any genetic marker for this intolerance and, while treatment for this condition is also a gluten free diet, small amounts of gluten may be tolerated without causing damage to the small intestine. top ] When gluten is eliminated from the diet, the villi heal and the results of a biopsy will not be accurate or reliable. Individuals are advised to wait until they have been positively diagnosed with celiac disease before going on a gluten free diet. top ] Yes. Evidence suggests that first-degree relatives (parents, siblings, and children) have an elevated risk for celiac disease, as do second-degree relatives (grandparents, grandchildren, aunts, uncles, cousins) to a lesser extent. The Kogan Celiac Center recommends screening serology for these family members. top ] Gluten is a general term for certain proteins that are found in wheat, barley and rye and are responsible for triggering the autoimmune reaction that is the hallmark of celiac disease. There is currently some controversy about whether a similar protein found in oats causes a similar response. Individuals who follow a gluten free diet eliminate gluten and all derivatives of it from the food that they consume. Grains that are NOT acceptable on the gluten free diet are: wheat (otherwise known as enkorn, durum, faro, graham, kamut, semolina, spelt), rye, barley, and triticale (a cross between wheat and rye). Obvious places for the above grains are breads, pastas, and baked goods but processed foods can also contain other hidden sources of gluten. There are many grains and other sources of starch that are acceptable for anyone following a gluten free diet. The most common are corn, potatoes, rice and tapioca (sometimes called cassava). Other acceptable grains and sources of starch are: amaranth, arrowroot, buckwheat, millet, quinoa, sorghum (sometimes called jowar), sweet potato, taro, teff, and yam. Sometimes flour is made from beans, legumes and nuts. The Kogan Celiac Center is committed to providing expert nutritional education to help individuals manage the gluten free diet and accompanying lifestyle changes. top ] At present, there is no treatment for celiac disease other than strict, lifelong adherence to a gluten free diet. Exposure to even a small amount of gluten will cause damage to the small intestine... you cannot “grow out of” this disease! Over the course of time, intentional or non-intentional ingestion of gluten increases risk for many diseases including but not limited to lymphoma, osteoporosis and many other complications of malnutrition. top ] The Kogan Celiac Center offers comprehensive testing and treatment for adults and children with celiac disease. The Center is dedicated to providing expert early assessment, diagnosis, treatment, education and support to improve the health and well being of those who have this disease. top ] The Center is located at the Barnabas Health Ambulatory Care Center, Suite 111, 200 South Orange Avenue, Livingston, New Jersey. For further information, you may call us at (973) 322-7272. top ] The Center offers nutritional counseling, periodic screenings, and community-based education events and provides comprehensive information regarding System healthcare professionals. Our nutritional education program, Celiac Steps to Success, divides the process of learning how to eat and live gluten free into easy, manageable steps. Patients meet with a Registered Dietitian at regular intervals and learn how to implement changes that meet dietary guidelines and address lifestyle needs. This sequence typically runs over a 6 month period, after which annual follow up visits are recommended. top ] Many national support organizations have local chapters which host regular support group meetings. The Kogan Celiac Center also hosts monthly support groups for adults, teens and children. Please call the Center for more details. top ] As of January 1, 2006, the Food Allergen Labeling and Consumer Protection Act requires manufacturers to provide certain information about the ingredients they use to make their products. They must specify in plain English any ingredient that contains protein from any of the eight major food allergens: milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, or soybeans. Consequently, an individual with Celiac Disease can know very quickly whether a product contains wheat; note, however, that there is no current requirement for barley and rye to be mentioned on a product’s label. This law also required the FDA to further examine gluten as an ingredient of concern and to make a final ruling regarding the use of the term “gluten free” on food labels by no later than August 2008. The final ruling is expected to define “gluten free” as meaning that a product must have less than a predetermined amount of gluten in it, usually measured in parts-per-million. Check here for up-to-date information as this law and the regulation of gluten labeling evolves. top ] It is currently believed that the gluten protein is too heavy to be transferred to food or drink during the distillation process. So, distilled alcohol is considered safe for those following a gluten free diet as long as no additional colorings or flavorings are added. However, traditional beer and other malt beverages are made with barley and are not gluten free – explore online to find gluten free beer that has been developed in past years. top ]
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Vjerojatno ste već čuli za celijakliju. O njoj se sve više priča i zauzima sve više prostora u medijima, a kako i ne bi kada sve više ljudi, poglavito mladih, obolijeva od ove pritajene bolesti. Ukratko, celijaklija je alergija na gluten. Bolest se ne može izliječiti i najčešće je genetski uvjetovana, odnosno prenosi se unutar obitelji te može mirovati godinama dok se jednom ne aktivira, a aktivatori mogu biti stres, operacije, razne infekcije te trudnoća. Bolest se razvija u crijevima, točnije u tankom crijevu, a nastaje zbog kompliciranih reakcija crijeva na gluten. Gluten se nalazi u hrani, ali i u drugim stvarima kao primjerice lijekovima, vitaminima pa čak i balzamima za usne. Hrana koja obiluje glutenom su žitarice, primjerice raž, ječam, pšenica, zob. Stoga je najbolje ove namirnice izbjegavati ukoliko nam je dijagnosticirana celijaklija. Također, treba znati da glutena, prije svega onoga iz pšenice, ima u mnogim drugim proizvodima, kao što su pekarski proizvodi, razni kupovni keksi, tjestenina i slično. Dakle, kada sve zbrojimo, možemo zaključiti da se oboljeli od celijaklije moraju mnogo toga odreći žele li normalno živjeti. Naime, prehrana bez glutena pomaže da se sluznica crijeva oporavi te tako obavlja svoju funkciju. Ukoliko se oboljeli od celijaklije ne pridržavaju strogih prehrambenih pravila, posljedice mogu biti kobne, a najčešće se razvija nekakav oblik tumora crijeva. No, s druge strane, ukoliko to čine, mogu voditi dug i normalan život. Simptomi celijaklije su kronični proljev ili zatvor, napuhnutost, grčevi, povraćanje, umor, anemija, trnci u tijelu, depresija, izostanak ili neredovita menstruacija, afte, slab apetit, slabost mišića i slično. Kod djece je posebno opasna jer, primjerice može usporiti pravilan razvoj puberteta. Kao što smo rekli, za ovu bolest nema lijeka, stoga je jedino rješenje da se stvari stave pod kontrolu – stroga bezglutenska dijeta. Ovo podrazumijeva prehranu bez žitarica, a dozvoljene namirnice su povrće, prije svega rajčica, soja, riba, heljda, brašno od graha i amaranta te proizvodi na kojim izričito piše kako ne sadrže gluten. Gotovih proizvoda na kojima je jasno deklarirano ima li ili nema glutena sve je više, upravo zbog toga što sve više ljudi boluje od ovoga poremećaja. Ukoliko sumnjate na celijakliju, najbolje je otići svom liječniku kako bi vas upustio na daljnje pretrage. Nemojte prije toga prestati uzimati gluten na vlastitu ruku jer postoji mogućnost da testovi neće pokazati pravo stanje stvari. Pretraga se radi vađenjem krvi te njezinom analizom na markere posebnih antitijela, ali i biopsijom tankog crijeva. Do rezultata se u nekim slučajevima pritajene celijaklije teško dolazi te treba biti uporan. A ako ste se pitali što je zapravo gluten, evo odgovora. To su bjelančevine kojih ima u žitaricama. Njihovi nazivi su glutelini, albumini, globulini i prolamini te oni oštećuju sluznicu koja zbog toga smanjeno upija važne nutrijente iz hrane. Foto: Sxc.hu