Dette kommer til udtryk ved subjektivt ubehag eller pinefuld uro samt et behov for ofte at ændre position i følgeskab med manglende evne til at sidde eller stå stille.
5 Akathisia/ psychomotor restlessness The use of duloxetine has been associated with the development of akathisia, characterised by a subjectively unpleasant or distressing restlessness and need to move often accompanied by an inability to sit or stand still.