Komitéen forstår, at nye in uitro-mutagenicitetsundersøgelser af 7hydroxycoumarin og orthohydroxyphenyleddikesyre, som er de væsentligste metabolitter hos mennesket hhv. rotten, er blevet gennemført fornylig af The Research Institute for Fragrance Materials i USA.
The Committee understands that new in vitro mutagenicity studies have been carried out recently, under the auspices of the Research Institute for Fragrance Materials, USA, on 7hydroxycoumarin and ortho-hydroxyphenylacetic acid, which are the major metabolites in man and rat respectively.