Det tog hele 40 år at udarbejde denne lovgivning, selv om den naturligvis indeholder mange undtagelser, fra 1967 (direktiv 67/458/EØF) til 2007, da Reach-forordningen trådte i kraft,
This legislation took as many as 40 years to be completed, although it naturally has many exceptions, from 1967 (Directive 67/458/ΕEC) to 2007, when the REACH Regulation entered into force;