Fluvoxamin (100 mg én gang daglig), en potent CYP1A2- hæmmer, mindskede den tilsyneladende plasma- clearance for duloxetin med omtrent 77% og øgede AUC0- t 6 gange.
Fluvoxamine (100 mg once daily), a potent inhibitor of CYP1A2, decreased the apparent plasma clearance of duloxetine by about 77% and increased AUCo-t 6-fold.