I en 24- ugers placebokontrolleret faktoriel undersøgelse af initial behandling gav sitagliptin 50 mg to gange dagligt i kombination med metformin (500 mg eller 1. 000 mg to gange dagligt) en signifikant
In a 24-week placebo-controlled factorial study of initial therapy, sitagliptin 50 mg twice daily in combination with metformin (500 mg or 1000 mg twice daily) provided significant improvements in glycaemic parameters compared with either monotherapy.