Hos patienter med hæmatologiske maligniteter var gennemsnitlig Vss 5 l/ kg, og gennemsnitlig clearance cirka 1300 ml/ time/ kg med en gennemsnitlig terminal halveringstid på cirka 4, 5 timer.
After single intravenous doses of 20 to 250 micrograms/ kg (healthy volunteers) and 60 micrograms/ kg (cancer patients), palifermin exhibited rapid extravascular distribution In patients with haematological malignancies mean Vss was 5 l/ kg and mean clearance about 1300 ml/ hour/ kg with an average terminal half-life of approximately 4.5 hours.