Denne testmetode er baseret på Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) BCOP Test Method Protocol (8), som blev udviklet efter en international valideringsundersøgelse (4) (5) (9) med bidrag fra European Centre for the Validation of Alternative Methods (ECVAM) og Japanese Center for the Validation of Alternative Methods (JaCVAM).
This test method is based on the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) BCOP test method protocol (8), which was developed following an international validation study (4)(5)(9), with contributions from the European Centre for the Validation of Alternative Methods (ECVAM) and the Japanese Center for the Validation of Alternative Methods (JaCVAM).