Insulinbehovet kan være nedsat under samtidig behandling med lægemidler med hypoglykæmisk aktivitet, f. eks. orale antidiabetika, salicylater (f. eks. acetylsalicylsyre), sulfapræparater, visse antidepressiva (monoaminooxidasehæmmere), visse angiotensin konverteringsenzym (ACE) hæmmere (captopril, enalapril), angiotensin II- receptorblokkere, beta- blokkere, octreotid eller alkohol.
Insulin requirements may be reduced in the presence of substances with hypoglycaemic activity, such as oral hypoglycaemics, salicylates (for example, acetylsalicylic acid), sulpha antibiotics, certain antidepressants (monoamine oxidase inhibitors), certain angiotensin converting enzyme inhibitors (captopril, enalapril), angiotensin II receptor blockers, beta-blockers, octreotide or alcohol.