Nationale kliniske vejledninger og behandlingsprotokoller angives at være under udarbejdelse eller revidering i Danmark, Irland, Ungarn, Portugal, Det Forenede Kongerige og Norge, og Slovakiet offentliggjorde retningslinjer for forvaltningen af metadonbehandling i 2004.
National clinical guidelines and treatment protocols are reported to be in preparation or being revised in Demark, Ireland, Hungary, Portugal, the United Kingdom and Norway, and Slovakia published guidance on methadone treatment administration in 2004.