Vedle toho byl v krvi přítomen i malý počet metabolitů střední polarity, produkty O- demetylace a oxygenace.
After single oral administration of radiolabeled pimecrolimus in healthy subjects, unchanged pimecrolimus was the major active substance-related component in blood and there were numerous minor metabolites of moderate polarity that appeared to be products of O-demethylations and oxygenation.