Do 620. godine, Muhammed je već bio izgubio dvije najveće podrške, Hatidžu, koja mu je bila supruga punih 25 godina, i plemenskog zaštitnika, amidžu Ebu Taliba. Dostigao je jednu od najnižih tačaka u svom životu.
By 620, Muhammad had also just lost two of his greatest supporters, his loyal wife of 25 years, Khadija, and his clan protector, his uncle Abu Talib.