<p>Yup, you had a caffeine overdose and some symptoms of acute caffeine toxicity.</p>

<p>Caffeine is metabolized by your liver, specifically by the CYP1A2 pathway of the cytochrome P450 enzyme complex and there are a lot of prescription drugs, foods and herbal remedies that will slow or speed up caffeine clearance (elimination).</p>

<p>What you could have done to speed up your recovery was to stay well hydrated, consider moderate aerobic exercise and if possible sleep through the worst of it. But to answer your question directly, a meal of charbroiled beef with cabbage, cauliflower or broccoli, all foods known to induce CYP1A2 activity would hasten caffeine elimination. </p>

<p>As would, in theory, the prescription drug regadenoson (adenosine agonist) or varied mild anti-anxiety or tranquilizers for symptomatic relief.</p>

<p>You'd especially want to avoid, if possible foods the following that would prolong the half life of caffeine: grapefruit juice, cumin, tumeric, St. John's wort, peppermint tea. And if practical avoid prescription drugs that would strongly inhibit CYP1A2 e.g. ciprofloxacin, fluoroquinolones, fluvoxamine, verapamil and oral contraceptives.</p>

CC BY-SA 4.0
2020-06-06T11:28:42.183Z
Those are some very specific health advice. While interesting and valuable, do you have some sources to back them up?
Ludwik
CC BY-SA 3.0
2018-02-18T16:03:59.353Z
2018-02-18T16:03:59.353Z
Modslacfilio
<p><strong>Yesterday I had a way too big, way too strong cup of 100% Robusta.</strong> I had never tried pure Robusta before, so I had no idea what I was getting into. I experienced strong caffeine effects 6+ hours after consumption, and had mildly shaking hands + felt a little ill for six more hours (and then I went to bed).</p>

<p>I'm fine now, but <strong>what could I have done (or eaten, drunk) to weaken the effects of said cup?</strong> There are "home remedies" for hangovers, and if one has eaten too spicy food, bread is usually good. What works on caffeine?</p>

CC BY-SA 3.0
2015-01-29T16:37:03.150Z
It was about 0.6 litres, so you're right, a cup isn't the correct word. Yeah, wasn't fun... I knew I'd had too much from the first 15 minutes. On the plus side, now I know my boundaries better, and I got a lot of programming done...
Ludwik
<health><caffeine>
How to weaken effects of caffeine after consumption
Ludwik
# How to weaken effects of caffeine after consumption

(Asked by: username_0 on 2015-01-29)

**Yesterday I had a way too big, way too strong cup of 100% Robusta.** I had never tried pure Robusta before, so I had no idea what I was getting into. I experienced strong caffeine effects 6+ hours after consumption, and had mildly shaking hands + felt a little ill for six more hours (and then I went to bed).

I'm fine now, but **what could I have done (or eaten, drunk) to weaken the effects of said cup?** There are "home remedies" for hangovers, and if one has eaten too spicy food, bread is usually good. What works on caffeine?

**Tags:** health, caffeine

> **Comments:**
> **username_0**: It was about 0.6 litres, so you're right, a cup isn't the correct word. Yeah, wasn't fun... I knew I'd had too much from the first 15 minutes. On the plus side, now I know my boundaries better, and I got a lot of programming done...  

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## 1 answers

### Answer by username_1 on 2018-02-18. Score: 2

Yup, you had a caffeine overdose and some symptoms of acute caffeine toxicity.

Caffeine is metabolized by your liver, specifically by the CYP1A2 pathway of the cytochrome P450 enzyme complex and there are a lot of prescription drugs, foods and herbal remedies that will slow or speed up caffeine clearance (elimination).

What you could have done to speed up your recovery was to stay well hydrated, consider moderate aerobic exercise and if possible sleep through the worst of it. But to answer your question directly, a meal of charbroiled beef with cabbage, cauliflower or broccoli, all foods known to induce CYP1A2 activity would hasten caffeine elimination.

As would, in theory, the prescription drug regadenoson (adenosine agonist) or varied mild anti-anxiety or tranquilizers for symptomatic relief.

You'd especially want to avoid, if possible foods the following that would prolong the half life of caffeine: grapefruit juice, cumin, tumeric, St. John's wort, peppermint tea. And if practical avoid prescription drugs that would strongly inhibit CYP1A2 e.g. ciprofloxacin, fluoroquinolones, fluvoxamine, verapamil and oral contraceptives.

> **Comments:**
> **username_0**: Those are some very specific health advice. While interesting and valuable, do you have some sources to back them up?  

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