<p>There is a wide variety of inhibitory neuron classes.  See here for a review of interneurons in the hippocampus: <a href="http://onlinelibrary.wiley.com/doi/10.1113/jphysiol.2004.078915/full" rel="nofollow noreferrer">P. Somogyi, T. Klausberger, J. Physiol. 562, 9–26 (2005).</a>.</p>

<p>Different classes of interneurons have different spike durations (e.g. "fast-spiking" or FS cells, generally used as a marker of putative PV+ interneurons).  Additionally, different classes of interneurons have different post-synaptic receptors with specific temporal and other characteristics.  For example, GABA-A receptors have time constants of ~10ms, whereas GABA-B receptors have time constants of ~100ms (and yes, there are subtypes of those receptor classes).  You can see a modeling paper I wrote for exploration of a use for different receptor classes, as well as more references for further research. <a href="http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.1854-12.2013" rel="nofollow noreferrer">H. Sanders, M. Berends, G. Major, M. S. Goldman, J. E. Lisman, J. Neurosci. 33, 424–429 (2013).</a>.</p>

CC BY-SA 3.0
2017-03-15T04:39:09.820Z
2017-03-15T04:39:09.820Z
honi
<p>Is there a difference in speed of impulses created by excitatory and inhibitory neurons?</p>

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2017-01-27T03:22:05.400Z
It is possible that they are different since the ion channels expressed in different cell types are different. I do not know of any studies though.
Memming
<neuroscience>
Excitatory impulse speed vs inhibitory
spacemonkey
# Excitatory impulse speed vs inhibitory

(Asked by: username_0 on 2017-01-25)

Is there a difference in speed of impulses created by excitatory and inhibitory neurons?

**Tags:** neuroscience

> **Comments:**
> **username_1**: It is possible that they are different since the ion channels expressed in different cell types are different. I do not know of any studies though.  

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## 1 answers

### Answer by username_2 on 2017-03-15. Score: 1 | Accepted answer

There is a wide variety of inhibitory neuron classes. See here for a review of interneurons in the hippocampus: [P. Somogyi, T. Klausberger, J. Physiol. 562, 9–26 (2005).](http://onlinelibrary.wiley.com/doi/10.1113/jphysiol.2004.078915/full).

Different classes of interneurons have different spike durations (e.g. "fast-spiking" or FS cells, generally used as a marker of putative PV+ interneurons). Additionally, different classes of interneurons have different post-synaptic receptors with specific temporal and other characteristics. For example, GABA-A receptors have time constants of ~10ms, whereas GABA-B receptors have time constants of ~100ms (and yes, there are subtypes of those receptor classes). You can see a modeling paper I wrote for exploration of a use for different receptor classes, as well as more references for further research. [H. Sanders, M. Berends, G. Major, M. S. Goldman, J. E. Lisman, J. Neurosci. 33, 424–429 (2013).](http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.1854-12.2013).


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