<p>You can use the <a href="http://www.med.harvard.edu/aanlib/home.html" rel="nofollow">Whole Brain Atlas by Harvard</a> to <a href="http://www.med.harvard.edu/aanlib/cases/caseNA/pb9.htm" rel="nofollow">look at the normal brain anatomy in 3-D with MRI/PET</a>.</p>

<p>Check the Anterior Commissure (AC) on the MRI and sync it with the PET or SPECT. It helps.</p>

<p>More specifically, select "Anterior Commissure" and T1/FDG and click sync to show all the orientations in the same modalities and anatomical structure. It helps to find the anterior commissure in a normal brain using nuclear medicine image.</p>

CC BY-SA 3.0
2016-08-13T07:05:41.167Z
Thanks, Henrique, however I want to find the anatomical point of interest in the particular image I have in hand. Usually it does not comes with an anatomical image overlayed, and it is really hard to pinpoint the anterior comissure. I guess the answer is that one can never exactly find the anterior comissure when all one has is the SPECT image, w/o the anatomical image to guide... Thanks anyways...
lf_araujo
CC BY-SA 3.0
2016-08-12T04:03:29.597Z
2016-08-26T18:05:17.517Z
2016-08-26T18:05:17.517Z
Henrique Amaral
<p>I am learning how to use SPM and ISAS to analyze ictal and interictal SPECT. However I am stuck at a point of their <a href="http://spect.yale.edu/analysis_details.html#set_origin" rel="nofollow noreferrer">tutorial</a>. </p>

<p>In the item 1.2 one has to set the origin for the SPECT image. That is, to pinpoint the <a href="https://en.wikipedia.org/wiki/Anterior_commissure" rel="nofollow noreferrer">anterior commissure</a>. This is a fairly easy task in a MRI, but very hard to do in a SPECT. How am I to find a tiny anatomical area in such a blurry image (like the one below)?</p>

<p><a href="https://i.sstatic.net/ajinL.gif" rel="nofollow noreferrer"><img src="https://i.sstatic.net/ajinL.gif" alt="enter image description here"></a></p>

<p>Are there any anatomical references that I should be using in order to find the approximate area for the anterior commissure?</p>

<p>Any help would be greatly appreciated.</p>

<neuroimaging><spm>
Finding the anterior comissure to set origin in a SPECT image using SPM/ISAS
lf_araujo
# Finding the anterior comissure to set origin in a SPECT image using SPM/ISAS

(Asked by: username_0 on 2016-01-05)

I am learning how to use SPM and ISAS to analyze ictal and interictal SPECT. However I am stuck at a point of their [tutorial](http://spect.yale.edu/analysis_details.html#set_origin).

In the item 1.2 one has to set the origin for the SPECT image. That is, to pinpoint the [anterior commissure](https://en.wikipedia.org/wiki/Anterior_commissure). This is a fairly easy task in a MRI, but very hard to do in a SPECT. How am I to find a tiny anatomical area in such a blurry image (like the one below)?

[![enter image description here](https://i.sstatic.net/ajinL.gif)](https://i.sstatic.net/ajinL.gif)

Are there any anatomical references that I should be using in order to find the approximate area for the anterior commissure?

Any help would be greatly appreciated.

**Tags:** neuroimaging, spm


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## 1 answers

### Answer by username_1 on 2016-08-12. Score: 1 | Accepted answer

You can use the [Whole Brain Atlas by Harvard](http://www.med.harvard.edu/aanlib/home.html) to [look at the normal brain anatomy in 3-D with MRI/PET](http://www.med.harvard.edu/aanlib/cases/caseNA/pb9.htm).

Check the Anterior Commissure (AC) on the MRI and sync it with the PET or SPECT. It helps.

More specifically, select "Anterior Commissure" and T1/FDG and click sync to show all the orientations in the same modalities and anatomical structure. It helps to find the anterior commissure in a normal brain using nuclear medicine image.

> **Comments:**
> **username_0**: Thanks, Henrique, however I want to find the anatomical point of interest in the particular image I have in hand. Usually it does not comes with an anatomical image overlayed, and it is really hard to pinpoint the anterior comissure. I guess the answer is that one can never exactly find the anterior comissure when all one has is the SPECT image, w/o the anatomical image to guide... Thanks anyways...  

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