<p>From what I understand, only the oligodendrocytes are affected in multiple sclerosis, and they are attacked by T cells which cross the blood-brain barrier. This leads me to two questions:</p>

<ol>
<li>How is the blood-brain barrier affected in MS that allows T lymphocytes to cross the barrier?</li>
<li>Why do the T lymphocytes attack the oligodendrocytes? And when they do, what is the mechanism for de-myelination?</li>
</ol>

<p>Thank you in advance!</p>

CC BY-SA 3.0
2015-03-26T12:44:56.520Z
I'm voting to close this question as off-topic because it is better suited for Biology.SE
AliceD
CC BY-SA 3.0
2015-04-02T13:10:16.110Z
Voted for deletion as it is answered on Bio: http://biology.stackexchange.com/questions/30242/how-does-de-myelination-occur-in-multiple-sclerosis
AliceD
<neuroscience><neuroanatomy><genetics>
How does de-myelination occur in multiple sclerosis?
Meep
# How does de-myelination occur in multiple sclerosis?

(Asked by: username_0 on 2015-03-08)

From what I understand, only the oligodendrocytes are affected in multiple sclerosis, and they are attacked by T cells which cross the blood-brain barrier. This leads me to two questions:

1. How is the blood-brain barrier affected in MS that allows T lymphocytes to cross the barrier?
2. Why do the T lymphocytes attack the oligodendrocytes? And when they do, what is the mechanism for de-myelination?

Thank you in advance!

**Tags:** neuroscience, neuroanatomy, genetics

> **Comments:**
> **username_1**: I'm voting to close this question as off-topic because it is better suited for Biology.SE  
> **username_1**: Voted for deletion as it is answered on Bio: http://biology.stackexchange.com/questions/30242/how-does-de-myelination-occur-in-multiple-sclerosis  

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