<p>On page 32 of &quot;Principles of Neural Science,&quot; it sates that, &quot;...the initial segment of the axon has the highest density of voltage-sensitive Na+ channels and therefore the lowest threshold for generating an action potential...&quot;</p>

CC BY-SA 4.0
2020-11-10T21:54:39.060Z
The quote you write already has an answer to one "why" question. Can you explain which "why" question you want answered? "Why" can be asked at many levels of analysis and it is ambiguous which level is intended.
Bryan Krause
CC BY-SA 4.0
2020-11-13T17:19:24.400Z
Is this the reference?: *Kandel, E. (2013). Principles of neural science. New York: McGraw-Hill.*
Tony Mobbs
CC BY-SA 4.0
2020-11-16T17:35:04.137Z
Yes, that is the reference.
HailieCochran
<neuroscience>
Why is a low threshold necessary for generating an action potential?
HailieCochran
# Why is a low threshold necessary for generating an action potential?

(Asked by: username_0 on 2020-11-10)

On page 32 of "Principles of Neural Science," it sates that, "...the initial segment of the axon has the highest density of voltage-sensitive Na+ channels and therefore the lowest threshold for generating an action potential..."

**Tags:** neuroscience

> **Comments:**
> **username_1**: The quote you write already has an answer to one "why" question. Can you explain which "why" question you want answered? "Why" can be asked at many levels of analysis and it is ambiguous which level is intended.  
> **username_2**: Is this the reference?: *Kandel, E. (2013). Principles of neural science. New York: McGraw-Hill.*  
> **username_0**: Yes, that is the reference.  

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## 0 answers

