<p>There is a physical connection.</p>

<p>Synapses are held together by adhesion molecules, like cadherins and neuroligins/neurexins. </p>

<p><a href="https://cshperspectives.cshlp.org/content/4/4/a005694.short" rel="noreferrer">Missler, M., Südhof, T. C., &amp; Biederer, T. (2012). Synaptic cell adhesion. Cold Spring Harbor perspectives in biology, 4(4), a005694.</a></p>

CC BY-SA 4.0
2019-08-16T16:46:01.483Z
2019-08-16T16:46:01.483Z
Bryan Krause
<p>When two neurons connect to form a synapse, between the pre-synaptic and post-synaptic cells some space is found (synaptic cleft). How does this keep in position if there is no physical connection between the two?</p>

<neuroanatomy>
How synapses are hold in place if they're not phisically attached?
Mattia
# How synapses are hold in place if they're not phisically attached?

(Asked by: username_0 on 2019-08-16)

When two neurons connect to form a synapse, between the pre-synaptic and post-synaptic cells some space is found (synaptic cleft). How does this keep in position if there is no physical connection between the two?

**Tags:** neuroanatomy


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## 1 answers

### Answer by username_1 on 2019-08-16. Score: 4 | Accepted answer

There is a physical connection.

Synapses are held together by adhesion molecules, like cadherins and neuroligins/neurexins.

[Missler, M., Südhof, T. C., & Biederer, T. (2012). Synaptic cell adhesion. Cold Spring Harbor perspectives in biology, 4(4), a005694.](https://cshperspectives.cshlp.org/content/4/4/a005694.short)


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