<p>The following is Figure 8.2 from <a href="https://mitpress.mit.edu/9780262041997/theoretical-neuroscience/" rel="nofollow noreferrer">Dayan &amp; Abbott (2001)</a>, p. 292:</p>
<p><a href="https://i.sstatic.net/CUUxx.jpg" rel="nofollow noreferrer"><img src="https://i.sstatic.net/CUUxx.jpg" alt="Dayan &amp; Abbott (2001), Fig. 8.2" /></a></p>
<p>It describes the phenomenon of long-term potentiation/depression (LTP/LTD): Change in synaptic strength (y-axis) is inversely proportional to pre/post-synaptic spike time difference (x-axis). The closer pre- and post-synaptic spike are together, the higher the change in synaptic strength. Does anybody know whether there exist openly available data for such experiments?</p>

CC BY-SA 4.0
2023-02-10T05:15:03.520Z
There are thousands of LTP papers; I'm sure some have open data, but they're all going to be quite different because they all have different research questions.
Bryan Krause
CC BY-SA 4.0
2023-02-10T12:51:11.077Z
@BryanKrause: Sure! Can you point me to one of those papers or a repository that has such data?
Joram Soch
CC BY-SA 4.0
2023-02-10T15:45:36.457Z
I think it's really something you should put some effort into yourself if you want the data.
Bryan Krause
<neuroscience><theoretical-neuroscience><neurophysiology><computational-modeling>
Are there open data for long-term potentiation/depression experiments?
Joram Soch
# Are there open data for long-term potentiation/depression experiments?

(Asked by: username_0 on 2023-02-09)

The following is Figure 8.2 from [Dayan & Abbott (2001)](https://mitpress.mit.edu/9780262041997/theoretical-neuroscience/), p. 292:

[![Dayan & Abbott (2001), Fig. 8.2](https://i.sstatic.net/CUUxx.jpg)](https://i.sstatic.net/CUUxx.jpg)

It describes the phenomenon of long-term potentiation/depression (LTP/LTD): Change in synaptic strength (y-axis) is inversely proportional to pre/post-synaptic spike time difference (x-axis). The closer pre- and post-synaptic spike are together, the higher the change in synaptic strength. Does anybody know whether there exist openly available data for such experiments?

**Tags:** neuroscience, theoretical-neuroscience, neurophysiology, computational-modeling

> **Comments:**
> **username_1**: There are thousands of LTP papers; I'm sure some have open data, but they're all going to be quite different because they all have different research questions.  
> **username_0**: @BryanKrause: Sure! Can you point me to one of those papers or a repository that has such data?  
> **username_1**: I think it's really something you should put some effort into yourself if you want the data.  

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## 0 answers

