<p>This picture in her talk (which is very good, by the way) refers to the study about <strong>amygdala hyperreactivity</strong> - see below. Essentially the picture shows <code>fMRI</code> scan differences between  controls and borderline patients when looking at <code>neutral</code>, <code>happy</code>, <code>sad</code> and <code>fearful</code> faces. Neutral faces and fixation point were used to transition between the exposure blocks to the emotional faces. Authors state the study points towards the role of greater amygdala activation in borderline patients being a key component to their emotional vulnerability in context of disturbed interpersonal relationships. To put it very simply - borderline patients' amygdala response (i.e. mostly - fear) is more sensitive. The speaker does not talk about the above picture in particular; it rather serves as a general illustration for her presentation.</p>

<p>Donegan, N. H., Sanislow, C. A., Blumberg, H. P., Fulbright, R. K., Lacadie, C., Skudlarski, P., … Wexler, B. E. (2003). Amygdala hyperreactivity in borderline personality disorder: implications for emotional dysregulation. Biological Psychiatry, 54(11), 1284–1293. <a href="https://doi.org/10.1016/S0006-3223(03)00636-X" rel="nofollow noreferrer">https://doi.org/10.1016/S0006-3223(03)00636-X</a></p>

<p>In addition I found a good overview article on neuroimaging in borderline patients:</p>

<p>Lis, E., Greenfield, B., Henry, M., Guilé, J. M., &amp; Dougherty, G. (2007). Neuroimaging and genetics of borderline personality disorder: a review. Journal of Psychiatry &amp; Neuroscience, 32(3), 162–173.</p>

CC BY-SA 4.0
2018-03-27T12:04:54.997Z
2020-01-15T17:04:33.750Z
2020-01-15T17:04:33.750Z
r0berts
<p>Starting from mark 21:50 in the lecture <a href="https://www.youtube.com/watch?v=_t_NqEP80GE" rel="nofollow noreferrer">BPD-related cognitive-perceptual difficulties and challenges in their diagnosis and treatment</a>, there is an image of brain scan in borderline patients:</p>

<p><img src="https://i.sstatic.net/jL5UC.jpg" alt=""></p>

<p>What does this image say? The speaker says that it's something about uncontrollable manipulation of borderline patients, but I'm not really sure.</p>

CC BY-SA 3.0
2017-09-06T21:12:58.387Z
Well, I didn't watch the whole video. But it seems that it's implying borderline patients are more reactive to facial expressions.That means they percieve facial expressions stronger than normal people. That means they can "read" you better than others and use this ability to manipulate u by reading your hidden emotions.
Shayan Kabiri
<brain><personality-disorder>
What is the meaning of the brain scan of borderline patients?
Ooker
# What is the meaning of the brain scan of borderline patients?

(Asked by: username_0 on 2017-09-02)

Starting from mark 21:50 in the lecture [BPD-related cognitive-perceptual difficulties and challenges in their diagnosis and treatment](https://www.youtube.com/watch?v=_t_NqEP80GE), there is an image of brain scan in borderline patients:

![](https://i.sstatic.net/jL5UC.jpg)

What does this image say? The speaker says that it's something about uncontrollable manipulation of borderline patients, but I'm not really sure.

**Tags:** brain, personality-disorder

> **Comments:**
> **username_1**: Well, I didn't watch the whole video. But it seems that it's implying borderline patients are more reactive to facial expressions.That means they percieve facial expressions stronger than normal people. That means they can "read" you better than others and use this ability to manipulate u by reading your hidden emotions.  

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## 1 answers

### Answer by username_2 on 2018-03-27. Score: 4 | Accepted answer

This picture in her talk (which is very good, by the way) refers to the study about **amygdala hyperreactivity** - see below. Essentially the picture shows `fMRI` scan differences between controls and borderline patients when looking at `neutral`, `happy`, `sad` and `fearful` faces. Neutral faces and fixation point were used to transition between the exposure blocks to the emotional faces. Authors state the study points towards the role of greater amygdala activation in borderline patients being a key component to their emotional vulnerability in context of disturbed interpersonal relationships. To put it very simply - borderline patients' amygdala response (i.e. mostly - fear) is more sensitive. The speaker does not talk about the above picture in particular; it rather serves as a general illustration for her presentation.

Donegan, N. H., Sanislow, C. A., Blumberg, H. P., Fulbright, R. K., Lacadie, C., Skudlarski, P., … Wexler, B. E. (2003). Amygdala hyperreactivity in borderline personality disorder: implications for emotional dysregulation. Biological Psychiatry, 54(11), 1284–1293. <https://doi.org/10.1016/S0006-3223(03)00636-X>

In addition I found a good overview article on neuroimaging in borderline patients:

Lis, E., Greenfield, B., Henry, M., Guilé, J. M., & Dougherty, G. (2007). Neuroimaging and genetics of borderline personality disorder: a review. Journal of Psychiatry & Neuroscience, 32(3), 162–173.


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