Per Game Table | Season | Age | Tm | Lg | Pos | G | GS | MP | FG | FGA | FG% | 3P | 3PA | 3P% | 2P | 2PA | 2P% | eFG% | FT | FTA | FT% | ORB | DRB | TRB | AST | STL | BLK | TOV | PF | PTS |
| 2007-08 | 22 | CHI | NBA | C | 74 | 31 | 20.7 | 2.4 | 5.0 | .482 | 0.0 | 0.0 | .000 | 2.4 | 4.9 | .484 | .482 | 1.8 | 2.6 | .691 | 2.4 | 3.3 | 5.6 | 1.1 | 0.9 | 0.9 | 1.2 | 2.3 | 6.6 |
| 2008-09 | 23 | CHI | NBA | C | 80 | 55 | 24.2 | 2.6 | 4.7 | .556 | 0.0 | 0.0 | .000 | 2.6 | 4.6 | .558 | .556 | 1.5 | 2.3 | .676 | 3.1 | 4.5 | 7.6 | 1.3 | 0.6 | 1.4 | 1.0 | 3.0 | 6.7 |
| 2009-10 | 24 | CHI | NBA | C | 64 | 54 | 30.1 | 4.1 | 8.1 | .504 | 0.0 | 0.0 | | 4.1 | 8.1 | .504 | .504 | 2.5 | 3.4 | .744 | 3.4 | 7.6 | 11.0 | 2.1 | 0.5 | 1.6 | 1.8 | 3.1 | 10.7 |
| 2010-11 | 25 | CHI | NBA | C | 48 | 48 | 32.8 | 4.4 | 8.4 | .525 | 0.0 | 0.0 | .000 | 4.4 | 8.4 | .526 | .525 | 2.9 | 3.9 | .739 | 3.8 | 6.6 | 10.4 | 2.2 | 1.0 | 1.5 | 1.9 | 3.3 | 11.7 |
| 2011-12 | 26 | CHI | NBA | C | 64 | 64 | 30.4 | 3.9 | 7.7 | .508 | 0.0 | 0.0 | .000 | 3.9 | 7.6 | .509 | .508 | 2.4 | 3.2 | .748 | 3.8 | 6.0 | 9.8 | 2.5 | 0.6 | 1.4 | 1.4 | 2.5 | 10.2 |
| 2012-13 | 27 | CHI | NBA | C | 66 | 64 | 36.8 | 4.6 | 9.5 | .481 | 0.0 | 0.1 | .000 | 4.6 | 9.5 | .485 | .481 | 2.7 | 3.6 | .751 | 3.9 | 7.2 | 11.1 | 4.0 | 1.2 | 2.1 | 2.7 | 2.8 | 11.9 |
| 2013-14 | 28 | CHI | NBA | C | 80 | 80 | 35.3 | 4.8 | 10.0 | .475 | 0.0 | 0.0 | .000 | 4.8 | 10.0 | .476 | .475 | 3.1 | 4.2 | .737 | 3.5 | 7.7 | 11.3 | 5.4 | 1.2 | 1.5 | 2.4 | 3.1 | 12.6 |
| 2014-15 | 29 | CHI | NBA | C | 67 | 67 | 30.6 | 2.8 | 6.4 | .445 | 0.0 | 0.0 | .000 | 2.8 | 6.3 | .447 | .445 | 1.6 | 2.6 | .603 | 3.3 | 6.4 | 9.6 | 4.7 | 0.7 | 1.1 | 1.8 | 3.0 | 7.2 |
| 2015-16 | 30 | CHI | NBA | C | 29 | 2 | 21.9 | 1.8 | 4.6 | .383 | 0.0 | 0.0 | .000 | 1.8 | 4.6 | .386 | .383 | 0.8 | 1.6 | .489 | 3.0 | 5.8 | 8.8 | 3.8 | 0.6 | 1.0 | 1.8 | 2.7 | 4.3 |
| 2016-17 | 31 | NYK | NBA | C | 46 | 46 | 22.1 | 2.2 | 4.4 | .490 | 0.0 | 0.0 | .000 | 2.2 | 4.4 | .493 | .490 | 0.7 | 1.7 | .436 | 3.5 | 5.2 | 8.8 | 2.2 | 0.7 | 0.8 | 1.3 | 2.8 | 5.0 |
| 2017-18 | 32 | NYK | NBA | C | 7 | 0 | 5.7 | 0.7 | 1.4 | .500 | 0.0 | 0.0 | | 0.7 | 1.4 | .500 | .500 | 0.3 | 0.6 | .500 | 0.9 | 1.1 | 2.0 | 0.6 | 0.3 | 0.3 | 0.6 | 0.7 | 1.7 |
| 2018-19 | 33 | MEM | NBA | C | 42 | 1 | 16.5 | 2.6 | 5.1 | .516 | 0.0 | 0.0 | .000 | 2.6 | 5.0 | .519 | .516 | 1.9 | 2.6 | .716 | 1.4 | 4.3 | 5.7 | 2.1 | 0.5 | 0.7 | 1.2 | 2.3 | 7.1 |
| 2019-20 | 34 | LAC | NBA | C | 5 | 0 | 10.0 | 0.8 | 1.6 | .500 | 0.0 | 0.0 | | 0.8 | 1.6 | .500 | .500 | 1.2 | 1.6 | .750 | 1.0 | 2.2 | 3.2 | 1.4 | 0.2 | 0.2 | 1.2 | 1.8 | 2.8 |
| Career | | | NBA | | 672 | 512 | 27.7 | 3.3 | 6.8 | .491 | 0.0 | 0.0 | .000 | 3.3 | 6.8 | .493 | .491 | 2.1 | 2.9 | .700 | 3.2 | 5.8 | 9.0 | 2.8 | 0.8 | 1.3 | 1.7 | 2.8 | 8.8 |
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| 9 seasons | | CHI | NBA | | 572 | 465 | 29.5 | 3.5 | 7.2 | .490 | 0.0 | 0.0 | .000 | 3.5 | 7.2 | .492 | .490 | 2.2 | 3.1 | .711 | 3.3 | 6.1 | 9.4 | 3.0 | 0.8 | 1.4 | 1.8 | 2.9 | 9.3 |
| 2 seasons | | NYK | NBA | | 53 | 46 | 19.9 | 2.0 | 4.0 | .491 | 0.0 | 0.0 | .000 | 2.0 | 4.0 | .493 | .491 | 0.7 | 1.5 | .439 | 3.2 | 4.7 | 7.9 | 2.0 | 0.6 | 0.7 | 1.2 | 2.5 | 4.6 |
| 1 season | | MEM | NBA | | 42 | 1 | 16.5 | 2.6 | 5.1 | .516 | 0.0 | 0.0 | .000 | 2.6 | 5.0 | .519 | .516 | 1.9 | 2.6 | .716 | 1.4 | 4.3 | 5.7 | 2.1 | 0.5 | 0.7 | 1.2 | 2.3 | 7.1 |
| 1 season | | LAC | NBA | | 5 | 0 | 10.0 | 0.8 | 1.6 | .500 | 0.0 | 0.0 | | 0.8 | 1.6 | .500 | .500 | 1.2 | 1.6 | .750 | 1.0 | 2.2 | 3.2 | 1.4 | 0.2 | 0.2 | 1.2 | 1.8 | 2.8 |