@Test
public void testThatOffTargetNonPathogenicVariantsAreStillScoredAndFailFilterWhenPassAllVariantsSetFalse() {

    instance = new PathogenicityFilter(PASS_ONLY_PATHOGENIC_AND_MISSENSE_VARIANTS);
    FilterResult filterResult = instance.runFilter(downstreamFailsFilter);
    FilterTestHelper.assertFailed(filterResult);
}