@Test
public void testVariantIsOutsideDomain() {

    VariantCoordinates variant = new SimpleVariantCoordinates(GenomeAssembly.HG19, 1, 5, "A", "T");
    instance = new TopologicalDomain(1, 1000, 10000, new HashMap<>());
    assertThat(instance.containsPosition(variant), is(false));
}