@Test
public void test1456139() throws Exception {

    SmilesParser p = new SmilesParser(DefaultChemObjectBuilder.getInstance());
    IAtomContainer mol = p.parseSmiles("Cc1nn(C)cc1[C@H]2[C@H](C(=O)N)C(=O)C[C@@](C)(O)[C@@H]2C(=O)N");
    IAtomContainer mol2 = DefaultChemObjectBuilder.getInstance().newInstance(IAtomContainer.class, mol);
    Assert.assertNotNull(mol2);
    Assert.assertEquals(22, mol2.getAtomCount());
}