@Test
public void testC45H71N7O10() throws ClassNotFoundException, CDKException, Exception {

    IRule rule = new NitrogenRule();
    IMolecularFormula formula = MolecularFormulaManipulator.getMajorIsotopeMolecularFormula("C45H71N7O10", builder);
    formula.setCharge(0);
    Assert.assertEquals(1.0, rule.validate(formula), 0.0001);
}