Beating of the cilia of ependymal cells appears to set up concentration gradients of guidance molecules, such as cytokines TNF-α (tumor necrosis factor) and IGF-1 (insulin-like growth factor), to direct migration of neuroblasts, such as in the RMS.
O batimento dos cílios das células ependimárias parece definir os gradientes de concentração de moléculas guia, tais como as citocinas TNF-α (fator de necrose tumoral) e IGF-1 (fator de crescimento insulínico), para orientar a migração de neuroblastos, tal como no RMS.