Myelofibrosis usually develops slowly. In its very early stages, many people don't experience signs or symptoms. But as disruption of normal blood cell production increases, signs and symptoms may include:
- Feeling tired, weak or short of breath, usually because of anemia
- Pain or fullness below your ribs on the left side, due to an enlarged spleen
- Pale skin
- Easy bruising
- Easy bleeding
- Excessive sweating during sleep (night sweats)
- Frequent infections
- Bone pain
When to see a doctor
Make an appointment with your doctor if you have any persistent signs and symptoms that worry you.