Serum containing flavivirus antibodies in ELISA were subsequently tested by serum cross-neutralization
assay for antibodies to FRV, MVEV, KUNV, Alfuy virus, KOKV, Stratford virus, and EHV as described previously (27).
This and other studies have underscored a widespread pattern of cross-neutralization
of antivenoms against heterologous Bothrops sp.
In spite of the antigenic differences between VSV serotypes, variable levels of cross-neutralization
are observed among VSIV-1, 2 e 3 (PAUSZEK et al.
Antigenic relationships between flaviviruses as determined by cross-neutralization
tests with polyclonal antisera.
This report (("A dual-strain feline calicivirus vaccine stimulates broader cross-neutralization
antibodies than a single-strain vaccine and lessens clinical signs in vaccinated cats when challenged with a homologous feline calicivirus strain associated with virulent systemic disease" in Journal of Feline Medicne and Surgery, 2010)) describes the ability of a vaccine containing two different strains of FCV to induce protection in vaccinated animals against many strains of the virus.
Several groups have recently revealed that chimeric VLP in which the cross-neutralization
epitope of L2 inserted induce cross-neutralizing antibodies more effectively (27,28).
Weiss told SCIENCE NEWS that this cross-neutralization
offers hope that broad-spectrum drugs may be effective against the changeable HIV-1 virus, which, like the influenza virus, is notorious for its rapid mutation rate (SN: 6/28/86, p.
Both serum samples strongly neutralized Zika virus, showing low or no cross-neutralization
of the 4 DENV serotypes (Table 1; online Technical Appendix Figure 1, panels C, D), consistent with primary Zika virus infection.
Studies shown that no antibody against ONN was produced eliminating the possibility of 2-way cross-neutralization
test between CHIK and ONN viruses (11,12).
Multiple studies have reported cross-neutralization
, but antigenic diversity among different EV-71 genotypes has also been observed (11-17).
Previous studies have established that cross-neutralization
occurs among different EV71 strains and genogroups (13,14).
Lack of detectable cross-neutralization
of HRTV by mouse hyperimmune ascites fluids containing high-titered antibodies to LSV, SCV, and RGV * Virus (challenge PRNT70 antibody titers dose, PFU) HRTV LSV SCV RGV HRTV (54) 160 <20 <20 <20 LSV (214) 20 >640 <20 <20 SCV (220) 20 <20 320 <20 RGV (14) <20 <20 <20 320 * HRTV, Heartland virus; LSV, lone star virus; [PRNT.