Scratch no more: Gene for itch sensation discovered
...enes they identified, GRPR stood out because it is present
in only a few nerve cells in the spinal cord known to relay pain and/or itch signals to the brain. So they began to study some mice that were missing the GRPR gene to find out how they were different from normal mice. "The research was a little disa...
Identified main genetic variants involved in response to HIV
...rmination of the progression of AIDS. During the present
study, obtained genetic data was compared to blood virus load in patients during the first two years after the infection, and also to the rhythm of immune degradation as a result of the infection. This type of comparison, known as association study, ...
Liver cancer patients with high serum levels of hepatitis B virus face poorer outcomes
...re high total bilirubin and HCV infection. “The present
study has shown that a pre-chemotherapy viral load...nced disease, the authors concluded, “Based on the present
findings, the incorporation of anti-viral therapies to reduce HBV viral load should be considered as...
Research team identifies new Alzheimer's gene
...and that the GAB2 protein produced by this gene is present
in those brain cells containing tangles. When the researchers silenced GAB2 in preliminary studies it increased a molecular process thought to play an important role in the development of tangles. Based on these findings, the researchers hypothesize ...
Envisat captures first image of Sargassum from space
...sary for photosynthesis. The amount of chlorophyll present
in vegetation plays an important role in determini...oductivity. "The 709 band used by MERIS is not present
on other ocean-colour sensors. It was essential to our detecting Sargassum," Gower said. "The MCI in...
Brain holds clues to bipolar disorder
...rlier and more efficiently. Dr. Phillips also will present
data illustrating how imaging can be used to identify biomarkers and how these markers can help clinicians determine which patients will respond best to certain treatments. Neuroimaging also can help predict which patients of those who are geneticall...
Newly found sensing system enables certain bacteria to resist human immune defenses
...dies show that all three components of aps must be present
for the system to function and effectively protect bacteria from AMPs. “We are aware that for gram-negative bacteria, PhoP/PhoQ has been called a premier target for antimicrobial drug discovery, but little corresponding work has been done with gra...
Dual-imaging technique useful before -- and during -- brain surgery
... and other neurological conditions. Leach will present
this preliminary research in a special scientific exhibit at the American Society of Neuroradiology’s annual meeting, June 9–13 in Chicago. To combine both functional MRI and diffusion tensor tractography images in the operating room, Leach and h...
Newly discovered antibody may be body's natural defense against Alzheimer's
... but they were never previously demonstrated to be present
in substantial quantities in blood from normal hum...terian Hospital/Weill Cornell Medical Center, will present
the findings on Monday, June 11, at 3:30 pm, at the "2nd Alzheimer's Association International Confe...
Researchers shed light on mechanism of action used by anti-cancer drug
...d by sorafenib remained largely unknown. In the present
work, Grant and his team found that in human leukemia cells, sorafenib induces a process known as endoplasmic reticulum (ER) stress, which results from accumulation of misfolded proteins in the ER. The ER is a subcellular structure which plays a key ...
Massive herds of animals found to still exist in Southern Sudan
...ugh we were telling people that wildlife was still present
in Southern Sudan, nobody believed us,” said Maj. Gen. Alfred Akwoch, undersecretary of the Ministry of the Environment, Wildlife Conservation, and Tourism. “Thanks to the aerial surveys, we now know that wildlife resources, including elephants, are ...
CT scan reveals ancient long-necked gliding reptile
... behavior evolved several times in reptiles and is present
in the Indonesian reptile Draco. ...
Study finds mix of disease processes at work in brains of most people with dementia
...ses with the number of different disease processes present
in the brain, according to a new study. The research was funded by the National Institute on Aging (NIA), part of the National Institutes of Health, and conducted at the Rush Alzheimer’s Disease Center at Rush University Medical Center in Chicago. Ju...
454 sequencing identifies HIV drug resistance at early stage
...limited to detecting resistance mutations that are present
at levels of approximately 20% or greater in the c...study clearly shows that even resistance mutations present
at the 1% level lead to premature failure of therapy” explained Michael Kozal, M.D. the senior autho...
Exploring the dark matter of the genome
...entromeric and telomeric regions, until later. The present
work extends the sequence into those regions." Repeating sequences are the hallmark of heterochromatin, and there are several distinct kinds. Simple, short repeats are called satellite DNAs, which tend to become more abundant near the centromeres...
Potent possibilities for parasite attack
...disease type, only 200 out of more than 8000 genes present
in each genome were found to be differentially dis...iven their lack of similarity to human genes, they present
a limited repertoire of potential targets for drug and vaccine development allowing researchers to o...
Mutating the entire genome
...n one of every million cells, not enough cells are present
in which subsequent steps can occur so that cancer develops. “If we now improve that 10,000-fold, the pool of cells [with translocated chromosomes] may be large enough to create a mouse that develops the cancer,” so the new method makes it easier...
Clot-dissolving agent may be beneficial in treatment of severe frostbite
...ite. “Candidates for this therapy are patients who present
with severe frostbite as suggested by full-thickness tissue involvement, hemorrhagic blisters and abnormal perfusion on either angiogram or pyrophosphate scanning. Initiation of therapy within 24 hours of rewarming also appears to be necessary. Exclu...
Researchers develop buckyballs to fight allergy
...acked with granules containing histamine. They are present
in nearly all tissues except blood. When mast cells are activated, inflammatory substances such as histamine, heparin and a number of cytokines are rapidly released into the tissues and blood, promoting an allergic response. The researchers found ...
Revealed -- Mosquito genes that could be controlling the spread of killer viruses
...ers, while the other transmits malaria. Beyond the present
descriptive work, functional studies will be needed to clarify exactly how this happens. “This study made us realise that the immune systems of insects are not static but evolve and differentiate rapidly, most likely in response to the differ...