An aminonucleoside antibiotic that is toxic to both prokaryotic and eukaryotic cells. It causes premature chain termination in protein synthesis and is widely used in cell culture as a selection agent.
Puromycin can be used in vitro as a selection agent for cells transfected with puromycin N-acetyl transferase gene (pac). It causes premature chain termination in protein synthesis, and is an inhibitor of aminopeptidase and enkephalinase.
Inhibitor of aminopeptidase and enkephalinase.