Years ago, around 330, the physician Samuel Hafenreffer said that itching is "an unpleasant sensation that provokes scratching". There is not a better definition even today. The medical term for itching is "pruritus", prurire the Latin term meaning "burning".
Itching is a particularly agonizing challenge for many people with EB. The itching is very uncomfortable, it has a spontaneous response - the scratching. It can have serious consequences in EB, because new blisters and sores usually form immediately in the places you have scratched. It is necessary to at least relieve itching and it is often possible.