AbstractA 66 ‐year‐old Asian female diagnosed with an occupied mass of the inferior vena cava (IVC) case with extension to the right atrium, bilateral renal vasculature, and venae iliaca communis, which caused severe thrombocytopenia and severe liver and kidney dysfunction. The postoperative pathological dia gnosis was high‐grade undifferentiated intimal sarcoma. There have been less than 10 cases of venous undifferentiated intimal sarcomas reported in the literature, three of which occurred in the IVC. Unfortunately, the patient died of multiple organ failure in the intensive care unit postoperativel y.
SARC018_SPORE02: Phase II Study of Mocetinostat Administered with Gemcitabine for Patients with Metastatic Leiomyosarcoma with Progression or Relapse following Prior Treatment with Gemcitabine-Containing Therapy.
A 40-year-old man with history of AIDS –Kaposi sarcoma involving retroperitoneal lymph nodes, and end-stage renal disease presented with several weeks of shortness of breath and right sided chest discomfort. Physical exam revealed numerous firm, hyperpigmented papules and nodules of the chest. The patient denied a history of antecedent acne and had no family history of hypertrophic or keloidal scarring. Lab work-up revealed thrombocytopenia. Imaging showed lung nodules and multifocal intrathoracic lymphadenopathy.