Try Ricky Gervais new podcast.
the pros and cons of technological invention, leading on to Karl's Malthusian concerns and a possible solution. There's a digression into the extra sensory perception of early hominids. Oh, and some Monkey News of course. Plus strange tales about lethal drinking vessels and stately homes.
I love his original version of The Office. The guy kills me. His partners on the podcast are funny. He plays off them well. The only thing about it that i hated was that it ended.
One of the reasons I just bought my slick iPod video was that he was podcasting. Ricky says this the first in a series of 12 podcasts, so I am not sure of his long term plans, but it is up there on the iTunes most popular.