GL Sciences was the first company to emphasize the critical importance of silica-gel purity and silanol "speciation" ( e.g. optimizing isolated, vicinal, geminal, and siloxane ratios ) in creating a silica with optimal chromatographic properties. Inertsil SIL-100Å represents, to this day in 2011, the best-of-the-best silica material available in the chromatography industry. It is the basis for the advanced Inertsil 3-Series (see below), and is available in 3, 5, and 8 micron particle size in column configurations ranging from capillary to 50mm ID preparative sizes for normal phase chromatography.
The Inertsil 3-series represents a major advance in performance over the original Inertsil 2-Series. Inertsil 3-Series phases, including ODS-3, ODS-3V, ODS-P, ODS-EP, C8-3, Ph-3, CN-3, NH2, Diol, and SIL-100Å, are based on a purer, higher surface area silica which is specially manufactured to provide maximum bonded phase coverage. The result is a series of columns which provide excellent peak shapes using simple eluents while operating at low pressure.