American Transplant Congress abstracts
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Articles tagged "Metalloproteinases"
Matrix Metalloproteinase-9 and Neutrophil Extracellular Traps in Human and Mouse Liver Ischemia and Reperfusion Injury
S. Duarte, A. Zarrinpar, R. W. Busuttil, A. J. Coito
Dumont-UCLA Transplant Center, Los Angeles, CA
*Purpose: Neutrophils are key mediators of ischemia/reperfusion injury (IRI) in orthotopic liver transplantation (OLT). Once activated, they release nuclear DNA web-like structures called neutrophil extracellular…
Double Deficiency of Gelatinase-A and Gelatinase-B Does Not Protect against Hepatic Ischemia Reperfusion Injury
S. Duarte, P. Matian, S. Ma, R. Busuttil, A. Coito.
Dumont-UCLA Transplant Center, Los Angeles.
Gelatinases, consisting of gelatinase A (MMP-2; 72 KDa) and gelatinase B (MMP-9; 92KDa), are a subgroup of matrix metalloproteinases (MMPs) with key roles in a…
Matrix Metalloproteinase-9 in Human Orthotopic Liver Transplant Biopsies.
S. Duarte, N. Datta, J. Baber, R. Busuttil, A. Zarrinpar, A. Coito.
The Dumont-UCLA Transplant Center, Los Angeles.
Liver ischemia reperfusion injury (IRI) is an inflammatory event that contributes to graft dysfunction in orthotopic liver transplantation (OLT). Matrix Metalloproteinases (MMPs) are responsible for…
Anti-Inflammatory Effects of AAV-Mediated TIMP-1 Gene Transfer in Hepatic Ischemia-Reperfusion Injury.
S. Duarte, T. Fujii, G. Lipshutz, R. Busuttil, A. Coito.
Matrix metalloproteinase-9 (MMP-9) is a key mediator of leukocyte migration across vascular barriers in hepatic ischemia/reperfusion injury (IRI). Tissue inhibitor of metalloproteinase1 (TIMP-1) is the…
Matrix Metalloproteinase-2 (MMP-2) Activity Protects Against Hepatic Ischemia Reperfusion Injury Through MMP-9-Dependent and MMP-9-Independent Mechanisms.
S. Duarte, P. Matian, H. Kato, R. Busuttil, A. Coito.
Matrix Metalloproteinases (MMPs) are a family of proteinases with key roles in tissue homeostasis, inflammation and repair. We have recently shown that MMP-9 and MMP-2,…
AAV-Mediated TIMP-1 Gene Therapy Ameliorates Hepatic Ischemia/Reperfusion Injury
Matrix metalloproteinase-9 (MMP-9) is a key mediator of leukocyte migration across vascular barriers in hepatic ischemia/reperfusion injury (IRI). Tissue inhibitor of metalloproteinase-1 (TIMP-1) is the…
Most Viewed Abstracts
Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
Penis Transplantation: First U.S. Experience.
Low GFR after Kidney Donation Is Not Chronic Kidney Disease
Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
Live Related Kidney Transplant Experience in Abuja, Nigeria – First Eight Cases Ever.
Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes
Evidence of a Clinically Significant Drug-Drug Interaction between Cannabidiol and Tacrolimus: A Case Report
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