Is hysterosalpingography an important tool in predicting fertility outcome?
Ben W.J. Mol*, Patricia Swart, Patrick M.M. Bossuyt, Fulco Van der Veen
Objective: To determine the prognostic significance of hysterosalpingography (HSG) for fertility outcome. Design: Retrospective cohort study. Setting: Infertility department of an academic hospital. Patient(s): Consecutive patients undergoing HSG for subfertility between May 1985 and November 1987. Intervention(s): Hysterosalpingography. Main Outcome Measure(s): Follow-up ended when pregnancy or tubal surgery occurred or at the day of last contact. Kaplan-Meier curves for the occurrence of spontaneous intrauterine pregnancy (IUP) were constructed for a normal HSG, a HSG with a one-sided abnormality, and a HSG with a two-sided abnormality. Fecundity rate ratios were calculated to express the association between HSG findings and the occurrence of spontaneous IUP. Result(s): Of 359 patients that were analyzed, 231 (64%) showed no tubal pathology on HSG, 67 (19%) had a one-sided tubal pathology, and 61 (17%) had a two-sided tubal pathology. The adjusted fecundity rate ratios were 0.81 (95% confidence interval 0.47 to 1.4) for a one-sided pathology and 0.30 (95% confidence interval 0.13 to 0.71) for a two-sided pathology. Correction for informative censoring and sensitivity analysis did not alter these results. Conclusion(s): One-sided tubal pathology detected on HSG has limited prognostic significance, whereas two-sided tubal pathology detected on HSG reduces fertility prospects considerably.
Fertility outcome
prognostic significance
Fingerprint Dive into the research topics of 'Is hysterosalpingography an important tool in predicting fertility outcome?'. Together they form a unique fingerprint.
Fertility Medicine & Life Sciences
Tubal Pregnancy Medicine & Life Sciences
Hospital Departments Medicine & Life Sciences
Mol, B. W. J., Swart, P., Bossuyt, P. M. M., & Van der Veen, F. (1997). Is hysterosalpingography an important tool in predicting fertility outcome? Fertility and Sterility, 67(4), 663-669. https://doi.org/10.1016/S0015-0282(97)81363-5
Is hysterosalpingography an important tool in predicting fertility outcome? / Mol, Ben W.J.; Swart, Patricia; Bossuyt, Patrick M.M.; Van der Veen, Fulco.
In: Fertility and Sterility, Vol. 67, No. 4, 04.1997, p. 663-669.
Mol, BWJ, Swart, P, Bossuyt, PMM & Van der Veen, F 1997, 'Is hysterosalpingography an important tool in predicting fertility outcome?', Fertility and Sterility, vol. 67, no. 4, pp. 663-669. https://doi.org/10.1016/S0015-0282(97)81363-5
Mol BWJ, Swart P, Bossuyt PMM, Van der Veen F. Is hysterosalpingography an important tool in predicting fertility outcome? Fertility and Sterility. 1997 Apr;67(4):663-669. https://doi.org/10.1016/S0015-0282(97)81363-5
Mol, Ben W.J. ; Swart, Patricia ; Bossuyt, Patrick M.M. ; Van der Veen, Fulco. / Is hysterosalpingography an important tool in predicting fertility outcome?. In: Fertility and Sterility. 1997 ; Vol. 67, No. 4. pp. 663-669.
@article{ab650b13def9463abeebdba703a35f10,
title = "Is hysterosalpingography an important tool in predicting fertility outcome?",
abstract = "Objective: To determine the prognostic significance of hysterosalpingography (HSG) for fertility outcome. Design: Retrospective cohort study. Setting: Infertility department of an academic hospital. Patient(s): Consecutive patients undergoing HSG for subfertility between May 1985 and November 1987. Intervention(s): Hysterosalpingography. Main Outcome Measure(s): Follow-up ended when pregnancy or tubal surgery occurred or at the day of last contact. Kaplan-Meier curves for the occurrence of spontaneous intrauterine pregnancy (IUP) were constructed for a normal HSG, a HSG with a one-sided abnormality, and a HSG with a two-sided abnormality. Fecundity rate ratios were calculated to express the association between HSG findings and the occurrence of spontaneous IUP. Result(s): Of 359 patients that were analyzed, 231 (64%) showed no tubal pathology on HSG, 67 (19%) had a one-sided tubal pathology, and 61 (17%) had a two-sided tubal pathology. The adjusted fecundity rate ratios were 0.81 (95% confidence interval 0.47 to 1.4) for a one-sided pathology and 0.30 (95% confidence interval 0.13 to 0.71) for a two-sided pathology. Correction for informative censoring and sensitivity analysis did not alter these results. Conclusion(s): One-sided tubal pathology detected on HSG has limited prognostic significance, whereas two-sided tubal pathology detected on HSG reduces fertility prospects considerably.",
keywords = "Fertility outcome, hysterosalpingography, prognostic significance",
author = "Mol, {Ben W.J.} and Patricia Swart and Bossuyt, {Patrick M.M.} and {Van der Veen}, Fulco",
T1 - Is hysterosalpingography an important tool in predicting fertility outcome?
AU - Mol, Ben W.J.
AU - Swart, Patricia
AU - Bossuyt, Patrick M.M.
AU - Van der Veen, Fulco
N2 - Objective: To determine the prognostic significance of hysterosalpingography (HSG) for fertility outcome. Design: Retrospective cohort study. Setting: Infertility department of an academic hospital. Patient(s): Consecutive patients undergoing HSG for subfertility between May 1985 and November 1987. Intervention(s): Hysterosalpingography. Main Outcome Measure(s): Follow-up ended when pregnancy or tubal surgery occurred or at the day of last contact. Kaplan-Meier curves for the occurrence of spontaneous intrauterine pregnancy (IUP) were constructed for a normal HSG, a HSG with a one-sided abnormality, and a HSG with a two-sided abnormality. Fecundity rate ratios were calculated to express the association between HSG findings and the occurrence of spontaneous IUP. Result(s): Of 359 patients that were analyzed, 231 (64%) showed no tubal pathology on HSG, 67 (19%) had a one-sided tubal pathology, and 61 (17%) had a two-sided tubal pathology. The adjusted fecundity rate ratios were 0.81 (95% confidence interval 0.47 to 1.4) for a one-sided pathology and 0.30 (95% confidence interval 0.13 to 0.71) for a two-sided pathology. Correction for informative censoring and sensitivity analysis did not alter these results. Conclusion(s): One-sided tubal pathology detected on HSG has limited prognostic significance, whereas two-sided tubal pathology detected on HSG reduces fertility prospects considerably.
AB - Objective: To determine the prognostic significance of hysterosalpingography (HSG) for fertility outcome. Design: Retrospective cohort study. Setting: Infertility department of an academic hospital. Patient(s): Consecutive patients undergoing HSG for subfertility between May 1985 and November 1987. Intervention(s): Hysterosalpingography. Main Outcome Measure(s): Follow-up ended when pregnancy or tubal surgery occurred or at the day of last contact. Kaplan-Meier curves for the occurrence of spontaneous intrauterine pregnancy (IUP) were constructed for a normal HSG, a HSG with a one-sided abnormality, and a HSG with a two-sided abnormality. Fecundity rate ratios were calculated to express the association between HSG findings and the occurrence of spontaneous IUP. Result(s): Of 359 patients that were analyzed, 231 (64%) showed no tubal pathology on HSG, 67 (19%) had a one-sided tubal pathology, and 61 (17%) had a two-sided tubal pathology. The adjusted fecundity rate ratios were 0.81 (95% confidence interval 0.47 to 1.4) for a one-sided pathology and 0.30 (95% confidence interval 0.13 to 0.71) for a two-sided pathology. Correction for informative censoring and sensitivity analysis did not alter these results. Conclusion(s): One-sided tubal pathology detected on HSG has limited prognostic significance, whereas two-sided tubal pathology detected on HSG reduces fertility prospects considerably.
KW - Fertility outcome
KW - prognostic significance