JOSE MOURINHO is now favourite to become the first managerial casualty this season.
The Red Devils endured their first defeat of the campaign following a dismal 3-2 defeat away at Brighton.
Trouble appears to be brewing behind the scenes as Mourinho's relationship with the likes of Anthony Martial and Paul Pogba hits rock-bottom.
And if the Portuguese boss has lost the dressing room then surely it is only a matter of time before he receives the axe.
That is what the bookmakers believe with their latest odds in the Premier League managerial sack race.
He is now 9/2 favourite with Paddy Power, overtaking the likes of Newcastle's Rafa Benitez and Leicester's Claude Puel.
Benitez is 13/2 while Southampton boss Mark Hughes is 6/1.
And the bookmakers are so confident that the Red Devils won't win the Premier League they are offering a extraordinary price of 25/1.
Liverpool, Chelsea, Tottenham all have more chance of pipping Manchester City to the title.
While Mourinho works on how to salvage his season at United, fierce rivals City are in cruise control after strolling to a 6-1 win against Huddersfield.