Intracranial hemorrhage in herpes simplex encephalitis: An unusual presentation
Guliz Erdem, Paula A. Vanderford, Robert D. Bart
We describe a 14-month-old patient with atypical presentation of herpes simplex encephalitis. She initially presented with fever, lethargy, seizures, and large hemorrhages in the right parietal lobe, and clinical findings suggestive of a hypercoagulable state. The etiology of coagulation abnormality was not identified, although it was suggested as a possible causative factor in severe bleeding along with acute neuronal lysis as a result of infection. Although large intracerebral hemorrhages are occasionally described with systemic herpes infection, this presentation is unusual beyond the infant period.
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Herpes Simplex Encephalitis Medicine & Life Sciences 100%
Intracranial Hemorrhages Medicine & Life Sciences 80%
Hemorrhage Medicine & Life Sciences 45%
Febrile Seizures Medicine & Life Sciences 45%
Lethargy Medicine & Life Sciences 44%
Cerebral Hemorrhage Medicine & Life Sciences 38%
Parietal Lobe Medicine & Life Sciences 34%
Erdem, G., Vanderford, P. A., & Bart, R. D. (2002). Intracranial hemorrhage in herpes simplex encephalitis: An unusual presentation. Pediatric Neurology, 27(3), 221-223. https://doi.org/10.1016/S0887-8994(02)00428-9
Intracranial hemorrhage in herpes simplex encephalitis : An unusual presentation. / Erdem, Guliz; Vanderford, Paula A.; Bart, Robert D.
In: Pediatric Neurology, Vol. 27, No. 3, 09.2002, p. 221-223.
Erdem, G, Vanderford, PA & Bart, RD 2002, 'Intracranial hemorrhage in herpes simplex encephalitis: An unusual presentation', Pediatric Neurology, vol. 27, no. 3, pp. 221-223. https://doi.org/10.1016/S0887-8994(02)00428-9
Erdem G, Vanderford PA, Bart RD. Intracranial hemorrhage in herpes simplex encephalitis: An unusual presentation. Pediatric Neurology. 2002 Sep;27(3):221-223. doi: 10.1016/S0887-8994(02)00428-9
Erdem, Guliz ; Vanderford, Paula A. ; Bart, Robert D. / Intracranial hemorrhage in herpes simplex encephalitis : An unusual presentation. In: Pediatric Neurology. 2002 ; Vol. 27, No. 3. pp. 221-223.
@article{dc03888fec574b58a52a6b2e723f1748,
title = "Intracranial hemorrhage in herpes simplex encephalitis: An unusual presentation",
abstract = "We describe a 14-month-old patient with atypical presentation of herpes simplex encephalitis. She initially presented with fever, lethargy, seizures, and large hemorrhages in the right parietal lobe, and clinical findings suggestive of a hypercoagulable state. The etiology of coagulation abnormality was not identified, although it was suggested as a possible causative factor in severe bleeding along with acute neuronal lysis as a result of infection. Although large intracerebral hemorrhages are occasionally described with systemic herpes infection, this presentation is unusual beyond the infant period.",
author = "Guliz Erdem and Vanderford, {Paula A.} and Bart, {Robert D.}",
journal = "Pediatric Neurology",
T1 - Intracranial hemorrhage in herpes simplex encephalitis
T2 - An unusual presentation
AU - Erdem, Guliz
AU - Vanderford, Paula A.
AU - Bart, Robert D.
N2 - We describe a 14-month-old patient with atypical presentation of herpes simplex encephalitis. She initially presented with fever, lethargy, seizures, and large hemorrhages in the right parietal lobe, and clinical findings suggestive of a hypercoagulable state. The etiology of coagulation abnormality was not identified, although it was suggested as a possible causative factor in severe bleeding along with acute neuronal lysis as a result of infection. Although large intracerebral hemorrhages are occasionally described with systemic herpes infection, this presentation is unusual beyond the infant period.
AB - We describe a 14-month-old patient with atypical presentation of herpes simplex encephalitis. She initially presented with fever, lethargy, seizures, and large hemorrhages in the right parietal lobe, and clinical findings suggestive of a hypercoagulable state. The etiology of coagulation abnormality was not identified, although it was suggested as a possible causative factor in severe bleeding along with acute neuronal lysis as a result of infection. Although large intracerebral hemorrhages are occasionally described with systemic herpes infection, this presentation is unusual beyond the infant period.
JO - Pediatric Neurology
JF - Pediatric Neurology