Five-year outcomes after acute myocardial infarction in patients with and without diabetes mellitus in Taiwan, 1996-2005
Cheng Hung Chiang, Wei Chun Huang, Jin Shiou Yang, Chin Chang Cheng, Feng Yu Kuo, Kuan Rau Chiou, Tao Yu Lee, Tzu Wen Lin, Guang Yuan Mar, Chuen Wang Chiou, Chun Peng Liu, King Teh Lee
Background: Diabetes mellitus (DM) is a strong risk factor of cardiovascular disease. To date, the impact of DM on outcomes after acutemyocardial infarction (AMI) in Taiwan is undetermined. The aim of this study was to compare five-year outcomes after AMI in patients with and without diabetes in Taiwan. Methods: A nationwide cohort of 25,028 diabetic and 56,028 non-diabetic patients who were first hospitalized with AMI between 1996 and 2005 was enrolled through linkage with the Taiwan National Health Insurance research database. Patient mortality rates within 30 days after AMI, and 1, 3, and 5 years thereafter were compared. Result: Length of hospital stay (8.9 ± 8.7 vs. 8.2 ± 8.0 days, p < 0.01) and medical cost during admission (in Taiwan dollars: $129,123 ± $158,073 vs. $121,631 ± $157,018, p < 0.01) were significantly higher in diabetic patients. The difference in mortality rate within 30 days was insignificant between diabetic and non-diabetic patients (18.1% vs. 17.6%, p = 0.06). Mortalities within 1 year (31.0% vs. 26.8%, p < 0.01), 3 years (42.4% vs. 34.7%, p < 0.01), and 5 years (50.6% vs. 41.1%, p < 0.01)were significantly higher in diabetic patients. In patients with AMIwho underwent percutaneous coronary intervention (PCI) during index admission, the mortality rate within 30 days was insignificant (6.3% vs. 6.4%, p = 0.70) but mortalities within 1 year (15.2% vs. 11.6%, p < 0.01), 3 years (24.1% vs. 17.2%, p < 0.01), and 5 years (32.2% vs. 22.6%, p < 0.01) were significantly higher in diabetic patients. Conclusions: The average patient length of hospital stay and medical cost during admission were significantly higher in diabetic patients. Additionally, the difference in mortality rate within 30 days after AMI was insignificant between diabetic and non-diabetic patients. Also, long-term mortality after AMI was significantly higher in diabetic patients.
Acta Cardiologica Sinica
National Health Programs
Length of hospital stay
Medical cost
Chiang, C. H., Huang, W. C., Yang, J. S., Cheng, C. C., Kuo, F. Y., Chiou, K. R., ... Lee, K. T. (2013). Five-year outcomes after acute myocardial infarction in patients with and without diabetes mellitus in Taiwan, 1996-2005. Acta Cardiologica Sinica, 29(5), 387-394.
Five-year outcomes after acute myocardial infarction in patients with and without diabetes mellitus in Taiwan, 1996-2005. / Chiang, Cheng Hung; Huang, Wei Chun; Yang, Jin Shiou; Cheng, Chin Chang; Kuo, Feng Yu; Chiou, Kuan Rau; Lee, Tao Yu; Lin, Tzu Wen; Mar, Guang Yuan; Chiou, Chuen Wang; Liu, Chun Peng; Lee, King Teh.
In: Acta Cardiologica Sinica, Vol. 29, No. 5, 01.09.2013, p. 387-394.
Chiang, CH, Huang, WC, Yang, JS, Cheng, CC, Kuo, FY, Chiou, KR, Lee, TY, Lin, TW, Mar, GY, Chiou, CW, Liu, CP & Lee, KT 2013, 'Five-year outcomes after acute myocardial infarction in patients with and without diabetes mellitus in Taiwan, 1996-2005', Acta Cardiologica Sinica, vol. 29, no. 5, pp. 387-394.
Chiang CH, Huang WC, Yang JS, Cheng CC, Kuo FY, Chiou KR et al. Five-year outcomes after acute myocardial infarction in patients with and without diabetes mellitus in Taiwan, 1996-2005. Acta Cardiologica Sinica. 2013 Sep 1;29(5):387-394.
Chiang, Cheng Hung ; Huang, Wei Chun ; Yang, Jin Shiou ; Cheng, Chin Chang ; Kuo, Feng Yu ; Chiou, Kuan Rau ; Lee, Tao Yu ; Lin, Tzu Wen ; Mar, Guang Yuan ; Chiou, Chuen Wang ; Liu, Chun Peng ; Lee, King Teh. / Five-year outcomes after acute myocardial infarction in patients with and without diabetes mellitus in Taiwan, 1996-2005. In: Acta Cardiologica Sinica. 2013 ; Vol. 29, No. 5. pp. 387-394.
@article{19d438a252384f07b80a092f9c41c089,
title = "Five-year outcomes after acute myocardial infarction in patients with and without diabetes mellitus in Taiwan, 1996-2005",
abstract = "Background: Diabetes mellitus (DM) is a strong risk factor of cardiovascular disease. To date, the impact of DM on outcomes after acutemyocardial infarction (AMI) in Taiwan is undetermined. The aim of this study was to compare five-year outcomes after AMI in patients with and without diabetes in Taiwan. Methods: A nationwide cohort of 25,028 diabetic and 56,028 non-diabetic patients who were first hospitalized with AMI between 1996 and 2005 was enrolled through linkage with the Taiwan National Health Insurance research database. Patient mortality rates within 30 days after AMI, and 1, 3, and 5 years thereafter were compared. Result: Length of hospital stay (8.9 ± 8.7 vs. 8.2 ± 8.0 days, p < 0.01) and medical cost during admission (in Taiwan dollars: $129,123 ± $158,073 vs. $121,631 ± $157,018, p < 0.01) were significantly higher in diabetic patients. The difference in mortality rate within 30 days was insignificant between diabetic and non-diabetic patients (18.1{\%} vs. 17.6{\%}, p = 0.06). Mortalities within 1 year (31.0{\%} vs. 26.8{\%}, p < 0.01), 3 years (42.4{\%} vs. 34.7{\%}, p < 0.01), and 5 years (50.6{\%} vs. 41.1{\%}, p < 0.01)were significantly higher in diabetic patients. In patients with AMIwho underwent percutaneous coronary intervention (PCI) during index admission, the mortality rate within 30 days was insignificant (6.3{\%} vs. 6.4{\%}, p = 0.70) but mortalities within 1 year (15.2{\%} vs. 11.6{\%}, p < 0.01), 3 years (24.1{\%} vs. 17.2{\%}, p < 0.01), and 5 years (32.2{\%} vs. 22.6{\%}, p < 0.01) were significantly higher in diabetic patients. Conclusions: The average patient length of hospital stay and medical cost during admission were significantly higher in diabetic patients. Additionally, the difference in mortality rate within 30 days after AMI was insignificant between diabetic and non-diabetic patients. Also, long-term mortality after AMI was significantly higher in diabetic patients.",
keywords = "Acute myocardial infarction, Diabetes mellitus, Length of hospital stay, Medical cost, Mortality, National health insurance",
author = "Chiang, {Cheng Hung} and Huang, {Wei Chun} and Yang, {Jin Shiou} and Cheng, {Chin Chang} and Kuo, {Feng Yu} and Chiou, {Kuan Rau} and Lee, {Tao Yu} and Lin, {Tzu Wen} and Mar, {Guang Yuan} and Chiou, {Chuen Wang} and Liu, {Chun Peng} and Lee, {King Teh}",
journal = "Acta Cardiologica Sinica",
publisher = "Republic of China Society of Cardiology",
T1 - Five-year outcomes after acute myocardial infarction in patients with and without diabetes mellitus in Taiwan, 1996-2005
AU - Chiang, Cheng Hung
AU - Huang, Wei Chun
AU - Yang, Jin Shiou
AU - Cheng, Chin Chang
AU - Kuo, Feng Yu
AU - Chiou, Kuan Rau
AU - Lee, Tao Yu
AU - Lin, Tzu Wen
AU - Mar, Guang Yuan
AU - Chiou, Chuen Wang
AU - Liu, Chun Peng
AU - Lee, King Teh
N2 - Background: Diabetes mellitus (DM) is a strong risk factor of cardiovascular disease. To date, the impact of DM on outcomes after acutemyocardial infarction (AMI) in Taiwan is undetermined. The aim of this study was to compare five-year outcomes after AMI in patients with and without diabetes in Taiwan. Methods: A nationwide cohort of 25,028 diabetic and 56,028 non-diabetic patients who were first hospitalized with AMI between 1996 and 2005 was enrolled through linkage with the Taiwan National Health Insurance research database. Patient mortality rates within 30 days after AMI, and 1, 3, and 5 years thereafter were compared. Result: Length of hospital stay (8.9 ± 8.7 vs. 8.2 ± 8.0 days, p < 0.01) and medical cost during admission (in Taiwan dollars: $129,123 ± $158,073 vs. $121,631 ± $157,018, p < 0.01) were significantly higher in diabetic patients. The difference in mortality rate within 30 days was insignificant between diabetic and non-diabetic patients (18.1% vs. 17.6%, p = 0.06). Mortalities within 1 year (31.0% vs. 26.8%, p < 0.01), 3 years (42.4% vs. 34.7%, p < 0.01), and 5 years (50.6% vs. 41.1%, p < 0.01)were significantly higher in diabetic patients. In patients with AMIwho underwent percutaneous coronary intervention (PCI) during index admission, the mortality rate within 30 days was insignificant (6.3% vs. 6.4%, p = 0.70) but mortalities within 1 year (15.2% vs. 11.6%, p < 0.01), 3 years (24.1% vs. 17.2%, p < 0.01), and 5 years (32.2% vs. 22.6%, p < 0.01) were significantly higher in diabetic patients. Conclusions: The average patient length of hospital stay and medical cost during admission were significantly higher in diabetic patients. Additionally, the difference in mortality rate within 30 days after AMI was insignificant between diabetic and non-diabetic patients. Also, long-term mortality after AMI was significantly higher in diabetic patients.
AB - Background: Diabetes mellitus (DM) is a strong risk factor of cardiovascular disease. To date, the impact of DM on outcomes after acutemyocardial infarction (AMI) in Taiwan is undetermined. The aim of this study was to compare five-year outcomes after AMI in patients with and without diabetes in Taiwan. Methods: A nationwide cohort of 25,028 diabetic and 56,028 non-diabetic patients who were first hospitalized with AMI between 1996 and 2005 was enrolled through linkage with the Taiwan National Health Insurance research database. Patient mortality rates within 30 days after AMI, and 1, 3, and 5 years thereafter were compared. Result: Length of hospital stay (8.9 ± 8.7 vs. 8.2 ± 8.0 days, p < 0.01) and medical cost during admission (in Taiwan dollars: $129,123 ± $158,073 vs. $121,631 ± $157,018, p < 0.01) were significantly higher in diabetic patients. The difference in mortality rate within 30 days was insignificant between diabetic and non-diabetic patients (18.1% vs. 17.6%, p = 0.06). Mortalities within 1 year (31.0% vs. 26.8%, p < 0.01), 3 years (42.4% vs. 34.7%, p < 0.01), and 5 years (50.6% vs. 41.1%, p < 0.01)were significantly higher in diabetic patients. In patients with AMIwho underwent percutaneous coronary intervention (PCI) during index admission, the mortality rate within 30 days was insignificant (6.3% vs. 6.4%, p = 0.70) but mortalities within 1 year (15.2% vs. 11.6%, p < 0.01), 3 years (24.1% vs. 17.2%, p < 0.01), and 5 years (32.2% vs. 22.6%, p < 0.01) were significantly higher in diabetic patients. Conclusions: The average patient length of hospital stay and medical cost during admission were significantly higher in diabetic patients. Additionally, the difference in mortality rate within 30 days after AMI was insignificant between diabetic and non-diabetic patients. Also, long-term mortality after AMI was significantly higher in diabetic patients.
KW - Acute myocardial infarction
KW - Diabetes mellitus
KW - Length of hospital stay
KW - Medical cost
KW - Mortality
KW - National health insurance
JO - Acta Cardiologica Sinica
JF - Acta Cardiologica Sinica