Dr Jack Da Silva
My research and teaching are focused on evolutionary genetics. Current topics of interest are:
evolution of sex and recombination
evolution of sexes (anisogamy)
evolution of senescence (ageing)
evolution of eusociality
2003 - ongoing Senior Lecturer University of Adelaide
1986 - 1989 University of Oxford United Kingdom DPhil
1990 - 1992 NSERC Postdoctoral Fellow McGill University, Montreal Canada
Evolutionary Biology Molecular Evolution Population, Ecological and Evolutionary Genetics
2022 da Silva, J. (2022). The Extension of Foundress Life Span and the Evolution of Eusociality in the Hymenoptera. American Naturalist, 199(4), 16 pages.
2022 da Silva, J. (2022). Gene dynamics of haplodiploidy favor eusociality in the Hymenoptera. Evolution, 76(7), 1546-1555.
DOI Europe PMC1
2022 da Silva, J. (2022). The kin selection theory of genomic imprinting and modes of reproduction in the eusocial Hymenoptera. Biological Reviews, 19 pages.
2021 da Silva, J. (2021). Life History and the Transitions to Eusociality in the Hymenoptera. Frontiers in Ecology and Evolution, 9, 20 pages.
2020 da Silva, J. (2020). Williams' Intuition about Extrinsic Mortality Was Correct. Trends in Ecology and Evolution, 35(5), 378-379.
2019 da Silva, J. (2019). Plastic senescence in the honey bee and the disposable soma theory. The American Naturalist, 194(3), 367-380.
DOI Scopus5 WoS4 Europe PMC1
2019 da Silva, J. (2019). Correction: Plastic senescence in the honeybee and the disposable soma theory (American Naturalist, 194, 3, (2019), (367-380), 10.1086/704220). American Naturalist, 194(6), 881-884.
2018 da Silva, J. (2018). The evolution of sexes: A specific test of the disruptive selection theory. Ecology and Evolution, 8(1), 207-219.
2018 da Silva, J. (2018). Reports of the Death of Extrinsic Mortality Moulding Senescence Have Been Greatly Exaggerated. Evolutionary Biology, 45(2), 140-143.
2018 Da Silva, J., & Drysdale, V. (2018). Isogamy in large and complex volvocine algae is consistent with the gamete competition theory of the evolution of anisogamy. Proceedings of the Royal Society B: Biological Sciences, 285(1890), 6 pages.
2017 da Silva, J., & Galbraith, J. (2017). Hill-Robertson interference maintained by Red Queen dynamics favours the evolution of sex. Journal of Evolutionary Biology, 30(5), 994-1010.
2014 Da Silva, J., & Wyatt, S. (2014). Fitness valleys constrain HIV-1's adaptation to its secondary chemokine coreceptor. Journal of Evolutionary Biology, 27(3), 604-615.
DOI Scopus9 WoS10 Europe PMC7
2012 Da Silva, J. (2012). Antibody selection and amino acid reversions. Evolution, 66(10), 3079-3087.
DOI WoS1 Europe PMC1
2012 Da Silva, J. (2012). BRCA1/2 mutations, fertility and the grandmother effect. Royal Society of London. Proceedings B. Biological Sciences, 279(1740), 2926-2929.
2012 Da Silva, J. (2012). The dynamics of HIV-1 adaptation in early infection. Genetics, 190(3), 1087-1099.
2010 Da Silva, J., Coetzer, M., Nedellec, R., Pastore, C., & Mosier, D. (2010). Fitness epistasis and constraints on adaptation in a human immunodeficiency virus Type 1 protein region. Genetics, 185(1), 293-303.
2010 Da Silva, J. (2010). An adaptive walk by human immunodeficiency virus type 1 through a fluctuating fitness landscape. Evolution, 64(4), 1160-1165.
2009 Da Silva, J. (2009). Amino acid covariation in a functionally important human immunodeficiency virus type 1 protein region is associated with population subdivision. Genetics, 182(1), 265-275.
2009 Summers, K., Roney, K., Da Silva, J., Capraro, G., Cuthbertson, B., Kazianis, S., . . . McConnell, T. (2009). Divergent patterns of selection on the DAB and DXB MHC class II loci in Xiphophorus fishes. Genetica, 135(3), 379-390.
2006 Da Silva, J. (2006). Site-specific amino acid frequency, fitness and the mutational landscape model of adaptation in human immunodeficiency virus type 1. Genetics, 174(3), 1689-1694.
2003 Da Silva, J. (2003). The evolutionary adaptation of HIV-1 to specific immunity. Current HIV Research, 1(3), 363-371.
2002 Summers, K., Da Silva, J., & Farwell, M. (2002). Intragenomic conflict and cancer. Medical Hypotheses, 59(2), 170-179.
2002 Burke Da Silva, K., Mahan, C., & Da Silva, J. (2002). The Trill of the Chase: Eastern Chipmunks call to warn kin. Journal of Mammalogy, 83(2), 546-552.
2001 Hughes, A., Westover, K., Da Silva, J., O'Connor, D., & Watkins, D. (2001). Simultaneous positive and purifying selection on overlapping reading frames of the tat and vpr genes of Simian Immunodeficiency Virus. Journal of Virology, 75(17), 7966-7972.
2001 Ferguson, M., Maxwell, J., Vincent, T., Da Silva, J., & Olson, J. (2001). Comparison of the exoS gene and protein expression in soil and clinical isolates of pseudomonas aeruginosa. Infection and Immunity, 69(4), 2198-2210.
2001 Hughes, A., Da Silva, J., & Friedman, R. (2001). Ancient genome duplications did not structure the human Hox-bearing chromosomes. Genome Research, 11(5), 771-780.
DOI Scopus102 WoS92 Europe PMC76
1999 Evans, D. T., O'Connor, D. H., Jing, P., Dzuris, J. L., Sidney, J., Da Silva, J., . . . Watkins, D. I. (1999). Virus-specific cytotoxic T-lymphocyte responses select for amino-acid variation in simian immunodeficiency virus Env and Nef. Nature Medicine, 5(11), 1270-1276.
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1999 Gardezi, T., & Da Silva, J. (1999). Diversity in relation to body size in mammals: A comparative study. American Naturalist, 153(1), 110-123.
1999 Da Silva, J., & Hughes, A. L. (1999). Molecular phylogenetic evidence of cytotoxic T lymphocyte (CTL) selection on human immunodeficiency virus type 1 (HIV-1) [4]. Molecular Biology and Evolution, 16(10), 1420-1422.
1998 Da Silva, J., & Hughes, A. L. (1998). Conservation of cytotoxic T lymphocyte (CTL) epitopes as a host strategy to constrain parasite adaptation: Evidence from the nef gene of human immunodeficiency virus 1 (HIV-1). Molecular Biology and Evolution, 15(10), 1259-1268.
1996 Da Silva, J., & Bell, G. (1996). The ecology and genetics of fitness in Chlamydomonas. VII. The effect of sex on the variance in fitness and mean fitness. Evolution, 50(4), 1705-1713.
DOI Scopus12 Europe PMC2
1996 DaSilva, J., & Bell, G. (1996). The ecology and genetics of fitness in Chlamydomonas .7. The effect of sex on the variance in fitness and mean fitness. EVOLUTION, 50(4), 1705-1713.
DOI WoS13 Europe PMC3
1995 Woodroffe, R., Macdonald, D. W., & da Silva, J. (1995). Dispersal and philopatry in the European badger, Meles meles. Journal of Zoology, 237(2), 227-239.
1994 DASILVA, J., MACDONALD, D. W., & EVANS, P. G. H. (1994). NET COSTS OF GROUP LIVING IN A SOLITARY FORAGER, THE EURASIAN BADGER (MELES-MELES). BEHAVIORAL ECOLOGY, 5(2), 151-158.
DOI WoS70
1994 Zeyl, C., Bell, G., & da Silva, J. (1994). Transposon abundance in sexual and asexual populations of Chlamydomonas reinhardtii. Evolution, 48(4), 1406-1409.
1993 da Silva, J., Woodroffe, R., & Macdonald, D. W. (1993). Habitat, food availability and group territoriality in the European badger, Meles meles. Oecologia, 95(4), 558-564.
1992 da Silva, J., Bell, G., & Burt, A. (1992). Sources of variance in protein heterozygosity: the importance of the species-protein interaction.. Heredity, 68(3), 241-252.
1992 Da Silva, J., & Bell, G. (1992). The ecology and genetics of fitness in Chlamydomonas VI. Antagonism between natural selection and sexual selection. Proceedings of the Royal Society B: Biological Sciences, 249(1326), 227-233.
1991 Da Silva, J., Winquist, S. T., Weary, D. M., Inman, A. J., Mountjoy, D. J., Krebs, E. A., & Basolo, A. L. (1991). Male swords and female preferences. Science, 253(5026), 1426-1427.
DOI Scopus31 WoS7 Europe PMC3
1988 da Silva, J., & Terhune, J. M. (1988). Harbour seal grouping as an anti-predator strategy. Animal Behaviour, 36(5), 1309-1316.
1986 DASILVA, J., CAMERON, J. L., & FANKBONER, P. V. (1986). MOVEMENT AND ORIENTATION PATTERNS IN THE COMMERCIAL SEA-CUCUMBER PARASTICHOPUS-CALIFORNICUS (STIMPSON) (HOLOTHUROIDEA, ASPIDOCHRITIDA). MARINE BEHAVIOUR AND PHYSIOLOGY, 12(2), 133-147.
1985 DASILVA, J., & NEILSON, J. D. (1985). LIMITATIONS OF USING OTOLITHS RECOVERED IN SCATS TO ESTIMATE PREY CONSUMPTION IN SEALS. CANADIAN JOURNAL OF FISHERIES AND AQUATIC SCIENCES, 42(8), 1439-1446.
DOI WoS111
2008 Da Silva, J. (2008). Simulation of HIV-1 molecular evolution in response to chemokine coreceptors and antibodies. In D. Flower (Ed.), Immunionformatics (Vol. 9780387729688, pp. 161-178). USA: Springer.
2006 Da Silva, J. (2006). Parallel Monte Carlo Simulation of HIV Molecular Evolution in Response to Immune Surveillance. In A. Zomaya (Ed.), Parallel computing or bioinformatics and computational biology (pp. 29-57). Hoboken, New Jersey: Wiley.
2001 Hughes, A., Da Silva, J., & Verra, F. (2001). Evolutionary analysis of molecular sequence data. In Molecular Epidemiology: A Practical Approach (pp. 209-231). Great Britain: Oxford University Press.
2002 Da Silva, J., & Hughes, A. (2002). Monte Carlo simulation of HIV-1 evolution in response to selection by antibodies. In Proceedings 16th International Parallel and Distributed Processing Symposium (pp. 186-196). IEEE.
Past Higher Degree by Research Supervision (University of Adelaide)
2009 - 2013 Co-Supervisor Chloroplast DNAs Diversify Nuclear and Mitochondrial Genomes in Plants Doctor of Philosophy Doctorate Full Time Mr Dong Wang
2008 - 2013 Co-Supervisor Comprehensive Identification and Annotation of Non-Protein-Coding Transcriptomes from Vertebrates Indicates Most ncRNAs are Regulatory Doctor of Philosophy Doctorate Full Time Dr Zhipeng Qu
Position: Senior Lecturer
Email: jack.dasilva@adelaide.edu.au
Building: Molecular Life Sciences, floor 2
Org Unit: Molecular and Biomedical Science