Developing quantitative MRI for biomedical applications. I am particularly interested in exploiting the capabilities of functional and anatomical ultra-high field MRI in neuroscience, in using the increased contrast to noise ratio available at ultrahigh field to study 'single trial' fMRI of brain function, and in developing techniques to probe the origin of the BOLD effect which is responsible for fMRI. I am also the physics lead on a unique interdisciplinary project which has developed MRI methods to study many aspects of gastrointestinal (GI) function; this could revolutionize the diagnostic pathway for patients with GI problems. I have a strong interest in apply quantitative imaging methods to studying human development particularly in the fetus. Finally in recent years I have taken a particular interest in studying the safety of MRI.