Embryonic Stem Cell News and Research
Using CRISPR To Produce Induced Pluripotent Stem Cells
An interview with Dr. Sheng Ding about using a modified version of the CRISPR-Cas9 system to produce induced pluripotent stem cells.
The effects of Huntington's disease can be seen as early as conception, finds new study
In a breakthrough study, scientists at the Rockefeller University have observed the effects of Huntington's disease in neurons as early as conception.
Rockefeller scientists develop system to model Huntington's in human embryonic stem cells
With new findings, scientists may be poised to break a long impasse in research on Huntington's disease, a fatal hereditary disorder for which there is currently no treatment.
UCLA scientists coax human stem cells to become sensory interneurons
Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have, for the first time, coaxed human stem cells to become sensory interneurons -- the cells that give us our sense of touch.
Researchers find efficient way to produce neurons from pluripotent stem cells
Since their discovery in 2006, induced pluripotent stem cells are a glimmer of hope for many diseases. But further research of the complex regulation of pluripotent stem cell identity revealed unexpected difficulties.
Researchers find multiple new mutations linked to autism in children but not their parents
Most cases of autism appear to be associated with the appearance of new mutations that are not inherited from the child's parents, researchers from the University of Washington School of Medicine report.
Sophisticated 'social control' system allows embryos to protect purity of pluripotent cell population
A sophisticated system of 'social control' operating between neighboring cells allows embryos to protect the purity of their pluripotent cell population, which is able to generate all body tissues.
Research shows insulin as key determinant of embryonic stem cell potency
New research conducted at the stem cell centre, DanStem, at the University of Copenhagen shows that insulin is a key determinant of embryonic stem cell potency in mammals.
Researchers discover protein that makes stem cells into perfect allrounders
Researchers from the University of Zurich and the University Hospital Zurich have discovered the protein that enables natural embryonic stem cells to form all body cells.
Stowers scientists provide evidence of cross-talk between Nanog and Hox genes
Competing regulatory genes "talk" to each other to maintain balance of cell state, according to new research from the Stowers Institute for Medical Research.
Study sheds light on mechanisms that maintain gene activity in embryonic stem cells
Researchers from Turku, Finland, have discovered new information about the mechanisms which maintain gene activity in human embryonic stem cells.
UAB symposium highlights use of tissue engineering to repair broken hearts
The third annual Cardiovascular Tissue Engineering Symposium met at the University of Alabama at Birmingham last month, a gathering of noted physicians and scientists who share the goal of creating new tissues and new knowledge that can prevent or repair heart disease and heart attacks.
OTUD6B gene mutations linked to physical and intellectual deficits
An international team of researchers from institutions around the world, including Baylor College of Medicine, has discovered that mutations of the OTUD6B gene result in a spectrum of physical and intellectual deficits.
Scientists develop in vitro stem cell-based bioassay for detecting biological activity of BoNTs
Scientists at the Institute for Infectious Diseases, University of Bern have developed an in vitro stem cell-based bioassay grown on multi-electrode arrays capable of detecting the biological activity of Clostridium botulinum neurotoxins.
Cedars-Sinai researchers move closer to developing biological pacemaker with new $3 million NIH grant
With a new $3 million grant from the National Institutes of Health, Cedars-Sinai Heart Institute investigators are moving closer to their goal of developing a biological pacemaker that can treat patients afflicted with slow heartbeats.
UT Southwestern scientists unravel role of PARP enzymes in major cellular activities
A component of an enzyme family linked to DNA repair, stress responses, and cancer also plays a role in enhancing or inhibiting major cellular activities under physiological conditions, new research shows.
U of A researchers to study origin of Leigh's disease
Researchers at the University of Arkansas and their collaborators will use a $1.4 million grant from the U.S. Department of Defense to study the origin of Leigh's disease, a rare and incurable disease that affects the central nervous system.
De-bookmarking could be key to better reprogramming of fibroblasts into iPS cells
In reading, a bookmark tells where you stopped. Cells use bookmarks too, specific proteins that help the cell remember what collection of genes needs to be turned on again after the brief halt of gene expression during cell division.
Embryonic stem cell gene Nanog holds potential for reversing effects of aging
The fountain of youth may reside in an embryonic stem cell gene named Nanog.
Scientists uncover how changes in metabolism of embryonic stem cells can help engineer new blood vessels
Researchers from the University of Illinois at Chicago College of Medicine have uncovered how changes in metabolism of human embryonic stem cells help coax them to mature into specific cell types — and may improve their function in engineered organs or tissues.