I pulled up an old email response from COSC explaining how the GRE subject test credits are listed on the transcript.
Quote: The transcript breaks the GRE in Biology down only in the manner of levels: Basic/Introductory (6) credits – Intermediate (9) credits – upper (9) credits. We do not distinguish any subject matter on the transcript.
That looks pretty bad, doesn't it? If you're trying to prove to the USPTO or an employer that your general studies degree with a concentration is the equivalent of a major in biology, chemistry, etc., they won't be able to tell. Government jobs asking for specific courses or a minimum number of credits are going to look at transcripts.
I would recommend that anyone who really is relying on biology courses for their career to get most or all of their sciences and especially BIO courses in person with non-virtual labs.
Yeah, I wouldn't like that, but I think getting those credits would be cheap and fast. So if someone gets a Masters or grad cert, maybe they don't mind the checkbox degree.