Section 5. Breast: Overview: Current status of breast conserving therapy in Japan
Tadashi Ikeda, Hiromitsu Jinno, Akira Matsui, Yoko Mitsui, Sota Asaga, Tsuyoshi Mutoh, Masahiro Wada, Masaki Kitajima
研究成果: Short survey › 査読
Breast conserving operations have become the standard operation for early breast cancer. They were performed in about 40% of all breast cancer patients in Japan in 2000, and the percentage is still increasing. Ductal carcinoma in situ (DCIS) accounts for about 7% of all breast cancers and breast conserving operations for DCIS have been followed by a low in-breast recurrence rate, leading to wider indications for breast conserving operations as screening mammography has come to be used in Japan. In-breast recurrence is correlated to surgical margin status. It is important to evaluate the surgical margin for volume of cancer cell nests as well as for positivity. Neoadjuvant chemotherapy has become popular as an in vivo sensitivity test and as a means of down-staging to increase the possibility of performing a breast conserving operation. There are two patterns of shrinkage when neoadjuvant chemotherapy is effective: cocentric and honeycomb, and the pattern of residual cancer cell nests must be determined before surgery. MRI is an effective method of evaluating residual cancer cell nests. The in-breast recurrence rate after down-staging to perform breast conserving operations is reported to be higher than among candidates for breast conserving operation at the start. Sentinel node biopsy techniques and endoscopic operations are now being assessed in conjunction with breast conserving operations. The current status of breast conserving operations in Japan is reviewed in comparison with their status in Western countries.
Biomedicine and Pharmacotherapy
Published - 2002 11
フィンガープリント 「Section 5. Breast: Overview: Current status of breast conserving therapy in Japan」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。
Breast Medicine & Life Sciences
Carcinoma, Intraductal, Noninfiltrating Medicine & Life Sciences
Residual Neoplasm Medicine & Life Sciences
Margins of Excision Medicine & Life Sciences
Recurrence Medicine & Life Sciences
Ikeda, T., Jinno, H., Matsui, A., Mitsui, Y., Asaga, S., Mutoh, T., Wada, M., & Kitajima, M. (2002). Section 5. Breast: Overview: Current status of breast conserving therapy in Japan. Biomedicine and Pharmacotherapy, 56(SUPPL. 1), 182-186.
Section 5. Breast : Overview: Current status of breast conserving therapy in Japan. / Ikeda, Tadashi; Jinno, Hiromitsu; Matsui, Akira; Mitsui, Yoko; Asaga, Sota; Mutoh, Tsuyoshi; Wada, Masahiro; Kitajima, Masaki.
In: Biomedicine and Pharmacotherapy, Vol. 56, No. SUPPL. 1, 11.2002, p. 182-186.
Ikeda, T, Jinno, H, Matsui, A, Mitsui, Y, Asaga, S, Mutoh, T, Wada, M & Kitajima, M 2002, 'Section 5. Breast: Overview: Current status of breast conserving therapy in Japan', Biomedicine and Pharmacotherapy, vol. 56, no. SUPPL. 1, pp. 182-186.
Ikeda T, Jinno H, Matsui A, Mitsui Y, Asaga S, Mutoh T et al. Section 5. Breast: Overview: Current status of breast conserving therapy in Japan. Biomedicine and Pharmacotherapy. 2002 11;56(SUPPL. 1):182-186.
Ikeda, Tadashi ; Jinno, Hiromitsu ; Matsui, Akira ; Mitsui, Yoko ; Asaga, Sota ; Mutoh, Tsuyoshi ; Wada, Masahiro ; Kitajima, Masaki. / Section 5. Breast : Overview: Current status of breast conserving therapy in Japan. In: Biomedicine and Pharmacotherapy. 2002 ; Vol. 56, No. SUPPL. 1. pp. 182-186.
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title = "Section 5. Breast: Overview: Current status of breast conserving therapy in Japan",
abstract = "Breast conserving operations have become the standard operation for early breast cancer. They were performed in about 40% of all breast cancer patients in Japan in 2000, and the percentage is still increasing. Ductal carcinoma in situ (DCIS) accounts for about 7% of all breast cancers and breast conserving operations for DCIS have been followed by a low in-breast recurrence rate, leading to wider indications for breast conserving operations as screening mammography has come to be used in Japan. In-breast recurrence is correlated to surgical margin status. It is important to evaluate the surgical margin for volume of cancer cell nests as well as for positivity. Neoadjuvant chemotherapy has become popular as an in vivo sensitivity test and as a means of down-staging to increase the possibility of performing a breast conserving operation. There are two patterns of shrinkage when neoadjuvant chemotherapy is effective: cocentric and honeycomb, and the pattern of residual cancer cell nests must be determined before surgery. MRI is an effective method of evaluating residual cancer cell nests. The in-breast recurrence rate after down-staging to perform breast conserving operations is reported to be higher than among candidates for breast conserving operation at the start. Sentinel node biopsy techniques and endoscopic operations are now being assessed in conjunction with breast conserving operations. The current status of breast conserving operations in Japan is reviewed in comparison with their status in Western countries.",
keywords = "Breast cancer, Breast conserving operation, Japan",
author = "Tadashi Ikeda and Hiromitsu Jinno and Akira Matsui and Yoko Mitsui and Sota Asaga and Tsuyoshi Mutoh and Masahiro Wada and Masaki Kitajima",
journal = "Biomedicine and Pharmacotherapy",
publisher = "Elsevier Masson",
T1 - Section 5. Breast
T2 - Overview: Current status of breast conserving therapy in Japan
AU - Ikeda, Tadashi
AU - Jinno, Hiromitsu
AU - Matsui, Akira
AU - Mitsui, Yoko
AU - Asaga, Sota
AU - Mutoh, Tsuyoshi
AU - Wada, Masahiro
AU - Kitajima, Masaki
N2 - Breast conserving operations have become the standard operation for early breast cancer. They were performed in about 40% of all breast cancer patients in Japan in 2000, and the percentage is still increasing. Ductal carcinoma in situ (DCIS) accounts for about 7% of all breast cancers and breast conserving operations for DCIS have been followed by a low in-breast recurrence rate, leading to wider indications for breast conserving operations as screening mammography has come to be used in Japan. In-breast recurrence is correlated to surgical margin status. It is important to evaluate the surgical margin for volume of cancer cell nests as well as for positivity. Neoadjuvant chemotherapy has become popular as an in vivo sensitivity test and as a means of down-staging to increase the possibility of performing a breast conserving operation. There are two patterns of shrinkage when neoadjuvant chemotherapy is effective: cocentric and honeycomb, and the pattern of residual cancer cell nests must be determined before surgery. MRI is an effective method of evaluating residual cancer cell nests. The in-breast recurrence rate after down-staging to perform breast conserving operations is reported to be higher than among candidates for breast conserving operation at the start. Sentinel node biopsy techniques and endoscopic operations are now being assessed in conjunction with breast conserving operations. The current status of breast conserving operations in Japan is reviewed in comparison with their status in Western countries.
AB - Breast conserving operations have become the standard operation for early breast cancer. They were performed in about 40% of all breast cancer patients in Japan in 2000, and the percentage is still increasing. Ductal carcinoma in situ (DCIS) accounts for about 7% of all breast cancers and breast conserving operations for DCIS have been followed by a low in-breast recurrence rate, leading to wider indications for breast conserving operations as screening mammography has come to be used in Japan. In-breast recurrence is correlated to surgical margin status. It is important to evaluate the surgical margin for volume of cancer cell nests as well as for positivity. Neoadjuvant chemotherapy has become popular as an in vivo sensitivity test and as a means of down-staging to increase the possibility of performing a breast conserving operation. There are two patterns of shrinkage when neoadjuvant chemotherapy is effective: cocentric and honeycomb, and the pattern of residual cancer cell nests must be determined before surgery. MRI is an effective method of evaluating residual cancer cell nests. The in-breast recurrence rate after down-staging to perform breast conserving operations is reported to be higher than among candidates for breast conserving operation at the start. Sentinel node biopsy techniques and endoscopic operations are now being assessed in conjunction with breast conserving operations. The current status of breast conserving operations in Japan is reviewed in comparison with their status in Western countries.
KW - Breast conserving operation
M3 - Short survey
JO - Biomedicine and Pharmacotherapy
JF - Biomedicine and Pharmacotherapy