This paper, with No.22 State Farm, Agricultural Division No.2, XPCC as the example and under support of GIS, takes cultivated land plot as the evaluation unit and chooses 13 influence factors from five aspects of nutrient of cultivation layer, physical and chemical properties of cultivation layer, soil management, climate conditions and obstacle factor to establish desert oasis cultivated land fertility evaluation system and model. On the basis of a great quantity of information related to cultivated land fertility through field sampling and laboratory analysis, and supported by GIS, the papers takes advantages of mathematics method and mathematical model such as hierarchical analysis process and fuzzy comprehensive evaluation process to realize automatic and quantitative evaluation on cultivated land fertility, analyze area statistics and distribution characteristics of cultivated land fertility at different levels and main attribute of cultivated land at various classes in State Farm No.22, and give analysis of the space distribution. Results show that cultivated land in state farm No.22 can be divided into six classes, of which Class 1 Land IFI (integrated fertility index) is 0.74~1.00, area 3788.11 hm2 , accounting for 7.67% of the total area; Class 2 - Class 6 Land for36.45%, 43.47%, 12.32%, 0.089%and 0.0001% of the total area respectively. Research results are of significance in guiding local cultivated land quality management and promoting construction of new rural area.