Children's Hospital Oakland Home Find a Doctor Marsh, Anne M., MD
Find a Doctor Bio
Find a Doctor, Researcher, or Specialist
Search here by name, specialty, or department
Browse by Last Name:
Anne Marsh, MD
Director, Pediatric Sickle Cell Program
CLINICAL SPECIALTIES: Hemoglobinopathies, Transcranial Doppler, Pain, Virtual Reality for Pain Management
Department Location
Apheresis Program
747 52nd Street
Cancer & Blood Diseases Center
Comprehensive Center for Sickle Cell Disease
Walnut Creek Campus
2401 Shadelands Drive
University of Wisconsin School of Medicine and Public Health, WI
University of Wisconsin Hospital & Clinics, WI
(Pediatrics)
Children's Hospital & Research Center Oakland, CA
(Pediatric Hematology, Oncology)
Dr. Marsh was recruited as Director of the Pediatric Sickle Cell Program at UCSF Benioff Children's Hospital Oakland in 2015 because of her exceptional accomplishments during her fellowship. She has received a Patient Family award and teaching award. She supervises the clinical services for approximately 300 children locally and is the pediatric resource for the Western State Consortium. Dr. Marsh directs the Transcranial Doppler (TCD) Program including management of technicians and interpretations. The TCD program is integrated into clinic visits and includes satellite testing.SCD. This project, funded by an NIH Clinical Research Services-Pilot Research Award for Early Career Investigators, was successfully completed and generated novel findings pertaining to the pathophysiology of AVN in SCD. In collaboration with Frans Kuypers, PhD and the UC Berkeley Physiology division, she received a grant from the NFL to investigate the pathophysiology of sickle cell trait during intense exercise. She helps to conduct and oversee phase 1 through phase 3 sponsor and investigator-initiated clinical trials at the center and is an active participant in the HRSA-funded Pediatric Sickle Cell Regional Collaborative.
Dr. Marsh is a co-investigator on several NIH, HRSA, CDC, and pharmaceutical studies. Dr. Marsh was a research fellow in the red cell biology lab focusing on red cell microparticles and their clinical significance particularly in abnormalities of red cell membrane biology that contribute to the pathogenesis of avascular necrosis (AVN) in patients with SCD. This project, funded by an NIH Clinical Research Services-Pilot Research Award for Early Career Investigators, was successfully completed and generated novel findings pertaining to the pathophysiology of AVN in SCD. In collaboration with Frans Kuypers and the UC Berkeley Physiology division, she received a grant from the NFL to investigate the pathophysiology of sickle cell trait during intense exercise. She helps to conduct and oversee phase 1 through phase 3 sponsor and investigator-initiated clinical trials at our center and is an active participant in the HRSA-funded Pediatric Sickle Cell Regional Collaborative. Dr. Marsh is the principal investigator for a prospective study funded by Bayer Healthcare LLC evaluating biomarker changes during a vaso-occlusive crisis and the role of neutrophil elastase as a biomarker for the neutrophil-mediated pathobiology in sickle cell disease. She is the PI for the project virtual reality therapy as an adjunctive, non-pharmacologic distraction modality to alter the perception of pain in sickle cell disease. She is active as an advocate for the community and is a preceptor in the Community health and adolescent Program in Oakland.
Selected Research and Publications:
Marsh A and FA Kuypers. Research in Athletes with Sickle Cell Trait: Just Do It. Journal of Applied Physiology. 2012. 112(9):1433. PMID 22362400.
Marsh A, L Lo, R Cohen, and JH Feusner. Sorafenib and Bevacizumab for Recurrent Metastatic Hepatoblastoma: Stable Radiographic Disease with Decreased AFP. Pediatric Blood and Cancer.
2012. 59(5):939-940. PMID 22492703.
Marsh A, C Golden, C Hoppe, K Quirolo, E Vichinsky. Renal medullary carcinoma in an adolescent with sickle cell anemia. Pediatric Blood and Cancer. 2013 Sep 24. PMID 24108577.
M Treadwell, M Bell, S Leibovich, F Barreda, Marsh A, G Gildengorin, C Morris. A quality improvement initiative to improve emergency department care for pediatric patients with sickle cell disease. Journal of Clinical Outcomes Management. 2014. 21(2): 62-70.
A Lal, L Patterson, A Goldrich, Marsh A. Point-of-care end-tidal carbon monoxide reflects severity of hemolysis in sickle cell anemia. Pediatric Blood and Cancer. 2015. 62:912-4. PMID 25683629.
Marsh A, R Schiffelers, F Kuypers, S Larkin, G Gildengorin, W van Solinge, C Hoppe. Microparticles as biomarkers of osteonecrosis of the hip in sickle cell disease. British Journal Haematology. 2015. 168(1): 135-8. PMID 25196812.
S Kelly, K Quirolo, Marsh A, L Neumayr, A Garcia, B Custer. Erythrocytapheresis for chronic transfusion therapy in sickle cell disease: survey of current practices and review of the literature. Transfusion. 2016. In press.