AF1538a staining (0.5 µg/ml) of Jurkat lysate (RIPA buffer, 35 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
Goat Anti-HPK1 / MAP4K1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Phosphorylation of CARMA1 by HPK1 is critical for NF-kappaB activation in T cells. Brenner D, et al. Proc Natl Acad Sci U S A, 2009 Aug 25. PMID 19706536.
Proteasome-mediated degradation and functions of hematopoietic progenitor kinase 1 in pancreatic cancer. Wang H, et al. Cancer Res, 2009 Feb 1. PMID 19141650.
Prostaglandin E2 activates HPK1 kinase activity via a PKA-dependent pathway. Sawasdikosol S, et al. J Biol Chem, 2007 Nov 30. PMID 17895239.
Caspase-cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes. Brenner D, et al. Blood, 2007 Dec 1. PMID 17712048.
Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. Wu C, et al. Proteomics, 2007 Jun. PMID 17474147.