<|begin_of_text|><|start_header_id|>system<|end_header_id|>

You are an expert at identifying data availability statements in scientific text. A data availability statement describes where research data can be found or how it can be accessed.<|eot_id|><|start_header_id|>user<|end_header_id|>

Determine if the following text contains a data availability statement. Answer with 'yes' or 'no'.

Text: We observed a difficulty in reconciling the results obtained from experimental and synthetic data , especially for interaction callers . This can be most likely ascribed to the complexity of designing sound strategies to simulate Hi - C datasets with predefined features that represent well - defined and unambiguous true positives and negatives . Although several promising approaches are available from the biophysics of polymer folding modeling36 , no algorithm has been proposed so far to generate reads that fully mimic the distribution and biases observed in real Hi - C data . The availability of synthetic data will be essential to rationally tune any algorithm parameter , thus limiting the heuristics currently inherent in the choice of the best setting .<|eot_id|><|start_header_id|>assistant<|end_header_id|>

no<|eot_id|>