Studies of underground miners exposed to radioactive radon and its decay products have found that exposure increases risk of lung cancer.
Consequently, when radon was found to accumulate in houses, there was concern about the public health impact from exposure to a known carcinogen.
Estimates on the basis of studies of underground miners suggest that indoor radon may account for 6000-36000 lung cancer deaths each year in the United States.
Because of differences between working in underground mines and living in houses, estimates are subject to major uncertainties.
Numerous case-control studies were launched to assess directly the lung cancer risk from indoor radon.
Some studies report positive or weakly positive findings, while others report no increased risk.
Thus, the potential hazard from indoor radon remains answered only indirectly through miner studies, experimental animal studies, and cellular studies.
To provide more information on the risk of lung cancer from indoor radon, we conducted a meta-analysis of all case-control studies that included at least 200 case subjects each and that used long-term indoor radon measurements.
Eight studies were available and included a total of 4263 lung cancer case subjects and 6612 control subjects. (...)
Mots-clés Pascal : Tumeur maligne, Bronchopulmonaire, Facteur risque, Epidémiologie, Exposition, Radon, Gaz inerte, Radioisotope, Logement habitation, Etude cas témoin, Métaanalyse, Suède, Europe, Etats Unis, Amérique du Nord, Amérique, Chine, Asie, Finlande, Canada, Homme, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie
Mots-clés Pascal anglais : Malignant tumor, Bronchopulmonary, Risk factor, Epidemiology, Exposure, Radon, Inert gas, Radioisotope, Housing, Case control study, Metaanalysis, Sweden, Europe, United States, North America, America, China, Asia, Finland, Canada, Human, Respiratory disease, Lung disease, Bronchus disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0529592
Code Inist : 002B11A. Création : 13/02/1998.