Parasitic diseases caused by helminth and protozoan infections remain one of the largest global public health
problems for mankind. While natural immunity in man is rare or slow to develop for many parasites, the immune response
is capable of recognizing and responding to infection by utilizing a number of different immunological mechanisms. This
special topics journal issue examines many of the key findings in the recent literature regarding the immune response
against helminth and protozoan infections, as well as highlighting areas in which our current knowledge falls short. The
question of how we can tailor immune responses to prevent or reduce disease burden is a burning question within the field
Alternatively activated macrophages, B cells, helminth, innate lymphoid cells, parasite, protozoan, T cells, Tolllike
University of Arkansas for Medical Sciences, Department of Microbiology and Immunology, 4301 W. Markham St., Slot 511, Little Rock, AR 72205, USA.