The narrowing and hardening of arteries, caused by high cholesterol in the blood, which limits the flow of blood to organs and other parts of the body.
A substance made mainly by the liver, but also found in some foods, that circulates in the blood. The body needs cholesterol to stay healthy, but too little of one type and too much of another can cause health problems. Also see LDL.
Compass Care Manager
Member of your dedicated Compass team who works to help make the insurance process easier for you, helps you understand the cost of your treatment, and can refer you to independent financial assistance programs.
Compass Patient Education Manager
Member of your dedicated Compass team who provides education about HoFH, Juxtapid and the process of starting and staying on treatment.
Compass Registered Dietitian
Member of your dedicated Compass team who consults with you to customize a low-fat eating plan that works for you when you're first starting Juxtapid and as you continue to take Juxtapid.
FH (familial hypercholesterolemia)
A serious health condition in which high cholesterol is caused by defective genes rather than poor diet or lack of exercise. Also see HoFH.
A part of a cell passed down by parents that determines the traits and features of their children.
Relating to something you inherited from your parents. If a health problem is genetic, it means you inherited the problem genes from at least one of your parents.
HoFH (homozygous familial hypercholesterolemia)
A serious inherited condition in which the problem genes are passed down from both sides of the family and cause high cholesterol. HoFH is the least common and most severe form of FH.
Something passed down through one or both of your parents' genes. If a health problem is inherited, it means a problem gene caused it.
LDL (low-density lipoprotein) cholesterol
Also known as “bad“ cholesterol. If LDL cholesterol is too high, it can build up in arteries, and may cause health problems.
When taking certain medications such as Juxtapid®, your doctor will perform blood tests to check if your liver is functioning normally, as well as look for signs of liver problems.
Low-fat eating plan
While many people with high cholesterol are encouraged to stick to a heart-healthy diet, the Juxtapid low-fat eating plan is somewhat different because it is intended to help people avoid common stomach problems such as diarrhea and nausea.
A part of a study that is designed to monitor the safety and tolerability of a specific drug.
Prescription medicines that are used to reduce the amount of bad (LDL) cholesterol in the blood in the general population. People with HoFH may be able to reduce bad (LDL) cholesterol levels to a certain degree with statins, but adding an HoFH-specific treatment may help them get closer to their cholesterol goal.