Up to 99% of the calcium in the body is found in the hard tissues (tooth and bone). The remainder is distributed widely throughout the soft tissues and organs, performing a variety of important functions. Dietary calcium deficiency has also been associated with increased risk of hypertension, pre-eclampsia and colon cancer. Signs of magnesium deficiency include muscle tics and twitches, irregular heartbeat, convulsions, seizures, tremors and glandular disturbances. Trophic's Calcium and Magnesium are true chelated minerals and and have a combined molecular weight of about 850 daltons. This means that this form of the minerals is the most readily assimilated by the body because it is small enough to pass through the intestinal wall and is absorbed intact. The amino acids are then metabolized and the minerals are released into the bloodstream for immediate use without the need for Vitamin D.