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an enzyme of the oxydoreductase class that oxidizes unsaturated fatty acids to peroxides.
Lipoxidase was first discovered in 1934 in soybeans. It was later found to exist in the seeds of other plants and in the muscle tissue of fish and mammals. The principal substrates for lipoxygenase are linoleic, linolenic, and arachidonic acids and their respective esters. Lipoxidase is activated by polypeptides.