The Evolution of Lactase Persistence in some groups:
Detailed lesson Plan 2 with instructional materials
Lesson Plan: The Evolution of Lactase Persistence in Some Groups
Where in the Unit Sequence: Week 1: Lesson 2
Duration of Lesson: (1-2) 40 minute periods
Objective: To discover how the lactase persistence gene allele evolved independently in different populations based on the availability of milk in the diet.
Key Content: Lactase persistence is a mutation that was selected for by the availability of milk in the diet so some populations in the world have evolved to have this gene allele.
Key Vocabulary: Lactase, enzyme, adaptation, lactase persistence, mutation, chromosome, genes, alleles)
Key Skill (Standards).
NGSS.LS.1.3. Use argument supported by evidence for how the body is a system of interacting subsystems composed of groups of cells.
NGSS.LS.3.1 Develop and use a model to describe why structural changes to genes (mutations) located on chromosomes may affect proteins and may result in harmful, beneficial, or neutral effects to the structure and function of the organism.
NGSS.LS.1.1 Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential functions of life through systems of specialized cells.
PCSS.3.1.10.B1.5 Explain how mutations can alter genetic information and the possible consequences on cells.
PCSS.3.1.10.A3 Compare and contrast the life cycle of different organisms
PCSS.3.1.10.C2.2 Explain that mutations can alter a gene and are the original source of new variations in a population.
Detailed Facilitation Teacher will do… Direct students the activity handout-a google document which has the links to resources they can use to learn from and then type their answers to the questions. Walk around the room helping anyone needing it and engaging students in individual conversations about the content. In the last quarter of the class period lead a follow up discussion.
Detailed Activities Students will do: Students will use the video link and links to other resources to learn about this topic then they will fill in answers to the questions on the online document.
Assessment: Teacher observation of student participation in using the resources, completion of handout and in the discussion
Resources needed: google handout, student laptops
Homework: Students needing extra time or a modification to complete the handout
Lead a Discussion after the students have had time to work individually on the handout.
Essential Questions for the Discussion:
· What environmental factor caused some groups of people to evolve to be lactase persistent?
· How do groups of people who are 100% lactose intolerant survive and thrive?
· What do you think would happen if all European Americans suddenly became lactose intolerant and everyone else developed lactase persistence? Would that change anything?