Genomics technologies such as next-generation sequencing (NGS) and microarrays are accelerating neurogenomics research by revealing the mechanisms behind complex neurological diseases such as Alzheimer’s disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), and psychiatric disorders.
The interplay between heritable and nonheritable mutations, epigenetics, and other factors requires NGS-level analyses to increase our understanding. Arrays facilitate large-scale studies of genetic variants associated with neurological diseases. Illumina offers the NGS and array tools needed to make neurogenomics research possible.
Neuroscience researchers use NGS to identify variants for a microarray designed for ADHD, autism, and schizophrenia studies.Read Interview
Dr. Bosiljka Tasic discusses how single-cell mRNA sequencing is transforming neuronal classification efforts.Read Interview
Dr. Franco Taroni uses targeted sequencing to uncover novel genomic variants associated with metabolic and neurological disorders.Read Interview
Integrating whole-genome or exome sequencing with RNA sequencing and methylation array data in stem cells can help identify genes and pathways that play a role in neurological diseases.View Webinar
Dr. Jasmine Plummer from Cedars-Sinai Medical Center uses single-cell RNA sequencing and spatial capture technology to reveal spatial resolution of the developing human fetal cortex.View Webinar
Understand how variations in the human genome affect our response to medications. Pharmacogenomics (PGx) research can ultimately help maximize the benefits of treatment plans while reducing health care costs.Learn More
Dr. Jacob Michaelson, Associate Professor of Psychiatry at the University of Iowa, discusses how he uses genomic and computational techniques to study autism and other psychiatric disorders.Listen Now
Dr. Michael R. Wilson, Assistant Professor of Neurology at the University of California San Francisco, discusses how genomics can shed light on causes of brain inflammation.Listen Now
Experts discuss the genetics of dementia in this podcast episode, hosted by the UK Dementia Research Institute and Illumina.Listen Now
Explore gene expression patterns in individual cells within tissues of interest, or investigate the molecular mechanisms behind subpopulation responses to environmental cues.Learn More
Genomic technologies are introducing new avenues for understanding the etiology of complex diseases such as Parkinson's, Alzheimer's, autoimmune, and other disorders on a molecular level.Learn More
Find out how whole-genome sequencing and other genomic technologies can help scientists identify genetic variants linked to rare neurological and other disorders.Learn More