GeneralAngioedema is an acute, life-threatening allergic reaction, manifested by the sudden appearance of extensive swelling of the skin, subcutaneous tissue, fascia, muscles. This condition can develop at any age. About 10% of people at least once in your life suffered a similar condition.
Causes of angioedemaAt the heart of angioedema is of immediate type allergic reaction. Tissue swelling associated with the increased vascular permeability induced by the release of mediators (histamine, prostaglandins, leukotrienes, cytokines, etc.) from sensitized mast cells, basophils, when exposed to an allergen. As such an allergen may act foods (peanuts, chocolate, milk, exotic fruit, etc.), pollen or dust inhaled allergens and pharmaceuticals. In addition, the cause of angioedema may be the impact of different physical factors, such as cold, bright sunshine, and others
The symptoms of angioedemaAngioedema is usually found in areas with loose fiber - the lips, eyelids, cheeks, mucous membranes of the mouth, scrotum. It has a dense (the surface of the skin is not pressed when you click on it) character due to the high content of protein in the edema fluid.
Having held several hours to 2-3 days, then the swelling goes without a trace. Especially dangerous is the angioedema of the larynx (occurs in 30% of cases of angioedema). In this first noted hoarseness, "barking" cough, shortness of breath and then increases with shortness of breath. The complexion becomes bluish tint, then quickly fades. In the absence of a rational therapy, patients may die from suffocation.