- by scienceherb
What is Ginkgo biloba extract?
Ginkgo biloba extract is one of the most famous and top-selling herbal medicines. Ginkgo biloba is collected from green leaves of maidenhair tree which have been earlier dried. Ginkgo biloba extract is available as capsules, tablets, and liquid extracts. The therapeutic properties of this extract are believed to range from eye health improvement, blood disorders treatment, cardiovascular function improvement to healing memory problems.
Gingko biloba contains high levels of antioxidants such as flavonoids and terpenoids that provide protection against harmful free radicals that may cause oxidative cell damage. Also referred to as the maidenhair tree, ginkgo biloba tree is one of the oldest tree species in the earth. This tree can grow to more than 130 feet in height and can live for more than a century.
Ginkgo biloba extract uses
Ginkgo biloba extract uses include:
- (1) Assists In Fighting Inflammation
If you don’t know what inflammation is, don’t worry, here’s an explanation. Inflammation is part of the natural response of the body to invasion by a foreign substance or injury.
During this response, several immune system’s components are recruited to heal the injured area or fight against the foreign invader.
Several chronic diseases causes an inflammatory response even when there’s no injury or illness present. Over a period of time, the excessive inflammation may cause irreversible damage to the body’s DNA and tissues.
After several years of test-tube and animal research demonstrates that ginkgo biloba extract can lower inflammation markers in both animal and human cells in various states of diseases.
Some of the particular conditions in which ginkgo biloba extract has demonstrated to lower inflammation may include:
- Heart disease
- IBD (Irritable bowel disease)
- (2) Management of Peripheral arterial disease
Peripheral arterial disease is characterized by narrowing of blood vessels which causes poor flow of blood to the limbs. Modern research proves that taking ginkgo biloba leaf extract boosts the distance patients living with poor circulation of blood in their legs can walk pain-free. Taking ginkgo biloba may also lower the chances of requiring surgical procedures. However, persons with this condition may require to take ginkgo biloba for at least 6 months before they realize any improvement.
- (3) Improves COPD and Asthma Symptoms
Some studies show that ginkgo biloba may improve asthma symptoms and other inflammatory respiratory conditions such as COPD.
This is enabled by the anti-inflammatory compounds in biloba extract that reduces the inflammation of the airways and increases lung capacity.
A study with 75 persons studied the use of ginkgo biloba alongside glucocorticosteroid drug therapy for management of asthma symptoms.
The inflammatory compound levels in the saliva of the group which received biloba extract were incredibly lower than the group that received traditional medicine only.
Another research study involved 100 participants studied the efficiency of a collection of Chinese herbs, including biloba, for healing symptoms symptoms related to OCPD.
The participants who received the herbal formula containing ginkgo extract showed a remarkable decrease in bronchitis and cough at a 3-month follow-up, in comparison with the control group.
- (4) PMS (Premenstrual syndrome)
Taking ginkgo biloba extract by mouth relieves breast tenderness and other Premenstrual syndrome symptoms if the symptoms started at the 16th day of the cycle and continued up to the 5th day of the following menstrual cycle.
- (5) Lowers Symptoms of Dementia and Psychiatric Disorders
Ginkgo biloba extract has been studied for its potential to lower stress, anxiety, and other symptoms associated with cognitive decline associated with aging and Alzheimer’s disease.
Some research suggests a remarkable decrease in cognitive decline rate in persons with dementia who used ginkgo.
A summary of 21 studies showed that when applied in conjunction with regular medicine, ginkgo biloba may boost functional capabilities in patients with mild Alzheimer.
Another research evaluated 4 studies and noticed a remarkable reduction in dementia symptoms when ginkgo biloba was used for six months.
The beneficious results relates to the role that ginkgo biloba play in enhancing flow of blood to the brain.
- (6) Enhances Well-Being and Brain Function
It is believed that ginkgo biloba can improve functioning of the brain in healthy individuals.
Several studies shows that using ginkgo supplements may enhance mental performance and well-being. Results from these studies supports claims that link ginkgo biloba to enhanced focus, attention span, and memory.
Scientists believe that ginkgo extract enhances brain functioning since it protects the brain from neuronal damage while enhancing good blood circulation in the brain.
- (7) Reduces Anxiety
A recent research suggests that taking ginkgo supplements may reduce symptoms associated with anxiety.
Several animal studies have showed decline in the symptoms of anxiety and this is believed to be possible due to the antioxidant content of ginkgo.
In one trial, 170 persons with general anxiety were given either a placebo, 480 mg or 240 mg of ginkgo biloba extract. The sub-group which received the highest Ginkgo biloba extract dosage reported a 45 percent more decline in anxiety symptoms, compared to the subgroup which received a placebo.
- (8) Treatment of Depression
Animal studies show that supplementing with ginkgo biloba may assist treat depression symptoms.
Mice who took ginkgo extract before a stressful situation that couldn’t be avoided were less affected emotionally by stress than the study group that didn’t take the supplement.
The study concluded that these results were related to the anti-inflammatory properties of ginkgo extract that enhance the ability of the body to withstand when hormone levels related to stress are high.
- (9) Schizophrenia
Modern research indicates that taking ginkgo extract on a daily basis combined with conventional antipsychotic drugs for 2-4 months can lower symptoms associated with schizophrenia. The extract may also lower some side effects such as constipation and thirst and adverse effects which are associated with the antipsychotic drug known as haloperidol.
- (10) Treatment of Migraines and Headaches
In traditional medicine of China, ginkgo extract is a very famous treatment for migraines and headaches.
It is well known that biloba extract has antioxidant and anti-inflammatory effects. If a migraine or headache is due to excessive stress, ginkgo biloba may be beneficial.
Also, if a headache is caused by constricted blood vessels or decreased blood flow, the ability of this compound to dilate blood vessels may lessen symptoms.
Some migraines are however caused by blood vessels dilating excessively. In such a situation, ginkgo biloba may only have little effect.
If you’re planning to try ginkgo extract for your migraines, be sure that it won’t cause any harm if used correctly.
- (11) Tardive dyskinesia
Tardive dyskinesia is a movement condition which is caused by antipsychotic drugs. Research indicates that taking a particular ginkgo extract for 3 months may lower tardive dyskinesia severity in persons with schizophrenia who are under antipsychotic medications.
Taking ginkgo extract by mouth improves dizziness and balance disorders symptoms.
Ginkgo biloba extract dosage
Ginkgo biloba is available in liquid extracts, dried leaf for teas, capsule form, and as tablets.
In Ginkgo biloba extract dosage studies, adults have received between 120 to 240 milligrams per day in divided dosages. It took one to one and a half months before improvements are realized.
In medical studies, most clinical studies have exclusively used a standardized ginkgo extract. The said ginkgo biloba extract is standardized to 6 percent terpene lactones and 24 percent flavone glycosides. A common Ginkgo biloba extract dosage in patients with dementia is 40 mg of that extract 3 times per day. For enhancing cognitive ability in healthy persons, clinical trials have used between 120 mg and 600 mg of the ginkgo biloba extract per day.
People with premenstrual syndrome should take ginkgo biloba leaf extract of 80 mg received orally twice daily starting 16th day and continuing until the 5th day of the next cycle.
People with SSRI-induced sexual dysfunction should take 60-240 mg ginkgo leaf extract orally twice daily.
People with Vertigo/Tinnitus should take 120-160 mg/d leaf extract received by mouth in divided dosages twice to thrice per day.
People with raynaud’s disease should take 360 mg/d of ginkgo leaf extract received by mouth in divided dosages thrice per day.
People with normal tension glaucoma should take 40 mg of the leaf extract taken through mouth thrice per day for one month.
Ginkgo biloba extract benefits
Ginkgo biloba extract benefits which have been confirmed by research include:
- Packed with Powerful Antioxidants
High antioxidant content is the reason behind many Ginkgo biloba extract benefits. Ginkgo biloba extract contains high levels of terpenoids and flavonoids which are popular for their strong antioxidant results.
What antioxidants do is that they neutralize or combat the damaging effects of the free radicals which are highly reactive particles produced in the body. Free radicals are produced during the normal metabolic functions, such as detoxification or converting food to energy.
Free radicals, however, have the ability to cause damage to healthy cells, contributing to disease development and quick aging process.
Research on the ability of ginkgo extract to neutralize these free radicals have yielded highly promising results.
One study noted great improvements in the vision of persons with glaucoma who received 120 mg daily of gingko biloba in two months. Some research have also shown that gingko extract may assist patients with macular degeneration to maintain their sight for an extended period of time.
- Improving Quality of life
Modern research shows that taking ginkgo extract for 24 weeks may improve measures of quality of life including activities in daily living, sleep, alertness, and mood in older people.
- Reducing Radiation exposure
Studies shows that taking a particular ginkgo leaf extract known as Tanakan Ipsen (EGb 761) may lower most of the negative effects caused by harmful radiation on the body.
- Relieving radiation dermatitis
Radiation dermatitis is a skin condition caused by radiation therapy damage. Research shows that using a specific cream that contains ginkgo biloba and other may reduce skin negative effects and enhance skin moisture in breast cancer patients undergoing radiation treatments.
- Relieving Raynaud syndrome
Raynaud syndrome is condition characterized by painful response to cold specifically in the toes and fingers. Studies show that taking leaf extract for ginkgo for two and a half months orally may lower the frequency of painful attacks per week in patients with this condition.
- Improving Sexual problems which prevent satisfaction
Some studies shows that taking a certain combination product containing ginkgo, damiana, L-arginine, ginseng , multivitamins, and minerals for one month may enhance sexual satisfaction during sexual activity in women with sexual dysfunction.
Ginkgo biloba extract used for memory loss
Complaints of memory loss are usual with advancing age. Memory loss is associated with difficulties in retaining new information and learning.
Ginkgo biloba leaf extracts have been proved that they protect neurons from oxidative damage. As a result, they prevent tissue degeneration progression in people with memory loss. Also, this compound enhances blood flow throughout the body, restoring the balance between thromboxane A2 and prostacyclin which results in enhanced vasoregulation. Enhancement in the venous tone and vascular contraction are believed to be the result of release of catecholamines and phosphodiesterase inhibition.
Ginkgo biloba memory effects may also be due to the inhibition of cell death and toxicity induced by beta-amyloid peptides. Ginkgo biloba leaf extracts have also been found to;
- Inhibit monoamine oxidase A as well as B
- Inhibit an enzyme which breaks down adrenergic transmitters (catechol-O-methyl transferase),
- Increase the amount of alpha-adrenoreceptors in brain as there’s a decrease in alpha-adrenoreceptors with advancing age.
The other believed ginkgo’s mechanisms of action include effects on the benzodiazepine receptors.
Ginkgo biloba memory benefits may include:
- Enhanced memory and thinking
- Improved ability to carry out everyday tasks
- Improved social behavior
Other published research concluded that a certain form of ginkgo known as EGb 761 was safe to use and efficient in improving and stabilizing the social functioning of patients with poor memory for between 6 to 12 months.
Ginkgo biloba extract powder for sale
Going to the field looking for ginkgo plant and extracting the medicinal-rich extract can be a daunting task. It may not be easy to find the plant in your neighborhood and extracting the rich compounds of the plant requires some expertise, knowledge, and sophisticated equipment. To simplify the whole process for you, we have gathered the important medicinal components of the plant in largescale to produce Ginkgo biloba extract for sale.
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- Diamond BJ, Bailey MR. Ginkgo biloba: indications, mechanisms, and safety. Psychiatr Clin North Am 2013;36:73-83.
- Le Bars PL, Katz MM, Berman N, Itil TM, Freedman AM, Schatzberg AF. A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group. JAMA. 1997 Oct 22-29;278(16):1327-32
- Snitz BE, O’Meara ES, Carlson MC, et al. Ginkgo biloba for preventing cognitive decline in older adults: a randomized trial. JAMA 2009;302:2663-70.
- Schneider LS, DeKosky ST, Farlow MR, Tariot PN, Hoerr R, Kieser M. A randomized, double-blind, placebo-controlled trial of two doses of Ginkgo biloba extract in dementia of the Alzheimer’s type. Curr Alzheimer Res. 2005 Dec;2(5):541-51