The lining of the uterus (endometrium) responds to hormones made in the ovary. The pituitary gland at the base of the brain secretes a hormone called follicle stimulating hormone (FSH) which causes the egg follicles in the ovary to make estrogen. Estrogen causes the endometrium to thicken. When ovulation occurs, a second hormone (progesterone) is secreted by the ovary. This causes the lining of the uterus to become spongy. The corpus luteum, which makes the progesterone, lasts for fourteen days. When the progesterone and estrogen levels fall, the endometrium sheds in a menstrual period.
Is generally used to cover all forms of abnormal bleeding for which an organic cause cannot be found. DUB can be of two types:
Any stress, such as traveling or a new job can interfere with ovulation. Fortunately this will usually be temporary, and rarely requires treatment.