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6200 BCE: First copper smelting in Anatolia.
1700 BCE: The Hittites invade the region of the Hatti and begin a systematic campaign against them. The great city of Hattusa is sacked and destroyed.
1380 BCE: First instances of iron working in the Hittite Empire.
1350 BCE - 1250 BCE: The Hittite Empire is at its peak.
1334 BCE: Trojan War, according to Duris of Samos.
1285 BCE: Peak of Hittite power.
1250 BCE: Trojan War, according to Herodotus.
1200 BCE: Phrygians invade Anatolia and destroy the Hittite Empire.
1200 BCE: Lydia arises as a Neo-Hittite kingdom.
1184 BCE: Trojan War, according to Eratosthenes.
800 BCE - 700 BCE: Homer of Greece writes his Iliad and Odyssey.
687 BCE - 546 BCE: Mermnad dynasty rules Lydia.
609 BCE - 560 BCE: Reign of Alyattes of Lydia. Minting of first coins made from electrum.
560 BCE - 547 BCE: Reign of Croesus of Lydia.
547 BCE: Anatolia conquered by the Persians. Ephesos remains neutral.
499 BCE - 494 BCE: Ionian cities rebel against Persian rule.
498 BCE: Ionians and Greek allies invade and burn Sardis (capital of Lydia).
449 BCE: Ionian cities become independent from Persia under the Peace of Callias.
415 BCE: The Histories of Herodotus is published. The work is divided into nine chapters, each dedicated to one of the Muses.
279 BCE: Celts invade Thrace and Anatolia.
262 BCE: Eumenes rebels and wins against the Seleucid Antiochus I. Beginning of the Pergamon Empire.
218 BCE: The Aegosages Celts enter Anatolia under Attalos of Pergamon.
188 BCE: Maximum extent of the Pergamon Empire after Apamea peace.
188 BCE: The treaty of Apamea Kibotos. Peace and alliance is established between the Seleucid Empire and Rome joined by its allies, such as Pergamon and Rhodes. The Seleucids have to evacuate all the land and the cities from Asia Minor and to pay a huge war indemnity.
133 BCE: Attalus III, the last king of Pergamon, bequeathes the whole of Pergamon to Rome.
25 BCE: Galatia is peacefully absorbed into the Roman Empire.
42 CE - 62 CE: Paul the Apostle goes on missionary journeys across Asia Minor, Greece, and Rome.