Aim of the study was to study the effect of drug therapy on anatomical features. Observation of the anatomical defects and history of therapeutics taken by the patients and time of pregnancy when these drugs were prescribed, was recorded trimester wise.
In Modern therapeutics, the effects of different drugs alter the normal anatomical shape and growth of the new born child. Drugs these days are posing a major threat to the pregnant women and the growing foetus. These are called as teratogenic drugs. The so called monsters born with birth defects are all due to damage to the normal anatomical growth of foetus during crucial stages, for example during the period of organogenesis that is from 17th to 51st day of conception maximum damage is done. These are malformations and anatomical defects in the form of cleft palate, cleft lip and even seal limbs etc. The embryology has not been able to define why a particular effect is seen in a particular organ. But anatomical malformations due to drugs must be prevented by proper timing of the therapy. No drug should be prescribed in first trimester of pregnancy because all of these drugs are a source of potential danger to the growth and development of the child. Therefore, applied anatomy has sufficient role to play to guide therapeutics for proper outcome of treatment in the patients.
Drugs are harmful particularly in the first trimester. Therapeutics should be designed with the basis of applied anatomy and embryological growth.