Research in CTGlab explores the genetic and environmental causes of individual differences in brain-related health and disease. We integrate knowledge from different fields (genetics, neuroscience, bioinformatics, biology, machine learning), use and develop analytical tools to analyze and understand genomic data for complex traits, and connect to neuroscience to prove causation in wet-lab experiments.
Rachel Brouwer (assistant professor CNCR - CTG) recently published her work in Nature Neuroscience. The study is a large-scale collaboration of research groups worldwide and identifies genetic variants that are associated with the speed of structural brain changes over time.
Douglas Wightman (PhD student CNCR-CTG) publishes his first results in Nature Genetics. The large scale genetic study resulted in the discovery of novel genes and biological mechanisms that contribute to the pathogenesis of the disease.
Prof. dr. Danielle Posthuma has been awarded the 2021 Mensa Foundation Prize for her research directly identifying, for the first time, hundreds of human genes highly correlated to variations in intelligence.