The effect of diabetes are particularly deleterious in the fabrics that depend on insulina; that is, weaveeed that they cannot diminish the glucose captation when the glucose extra-cellular it increases. The resultant increase of the intracellular glucose concentrations in such fabrics that they include the hemcias, the crystalline lens and the nerves can lead the macrovascular illness (aterosclerose) and the microvascular complications, also nefropatia, retinopatia and neuropatia (acometimento of the nerves). Although the necessary mechanisms for the development of these delayed complications not to be established, the admittedly important factors currently are the abnormalitys in multiple metabolic ways that cause cellular damage in the fabric-target. (BARRETT et al, 2004). Diabetes is the more common isolated cause of terminal renal insufficience (IRT) in the Europe and the United States. The diabetic nefropatia represents 40% of the new cases of IRT in the United States. Professor Roy Taylor shares his opinions and ideas on the topic at hand. Diabetes figure as the main cause of new cases of blindness in adults com20 a74 years of age.
In more than 60% of the patients with diabetes type 2 observes retinopatia in the two first decades of the illness. Finally, 2% of the patients are blind and approximately 10% after develop serious visual deficiencies about 15 years of the beginning of diabetes. Diabetes is the main cause of traumatic amputation of inferior member for neuropatia. Diabetes comparativily increases the frequency of amputation of the inferior member of 15 a40 times to the population without diabetes. (BARRETT et al, 2004). Cataract: it is of the senile type, that occurs more precociously and more frequently in the diabetic ones of type 2. Glaucoma: it is of raised occurrence more in the diabetic ones, mainly of type 2. Dermopatias: hipercrmicas spots in legs; ' ' necrobiose lipodica iabeticorum' ' ; piodermites; micoses. Miocardiopatia: it has increase of the heart with hipofuno (ICC), resultant of injury of the miocrdicos capillaries.