Each model organism has its own advantages and disadvantages. Choosing an appropriate model depends on the question being asked. Many laboratories find it useful to perform parallel experiments in two or more model systems to understand different aspects of a biochemical process.
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A human is a complicated organism, and it is considered unethical to do many kinds of experiments on human subjects. For these reasons, biologists often use simpler “model” organisms that are easy to keep and manipulate in the laboratory.
The first model for the control of protein production was the lac operon. This system of feedback and negative regulation is used by bacteria, however, the general principles also apply to higher organisms. Another method of protein regulation involves