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Xolair Side Effects, Composition, Usage, and Dosage – Xolair is a drug containing omalizumab. Omalizumab is a drug used for patients who are indicated for asthma.
Omalizumab works with IgE binding and prevents the binding of IgE to high-affinity FcεRI receptors, thereby reducing the amount of free IgE available to trigger allergies. IgE is a contributing factor in allergic mechanisms.
- Group: Hard Drugs
- Therapeutic class: Anti asthma
- Content: Omalizumab 150 mg
- Shape: Powder Injection
Xolair Content and Composition
The content and composition of drug and supplement products are differentiated into two types, namely active content and inactive content.
Active content is a substance that can cause pharmacological activity or direct effects in the diagnosis, treatment, therapy, prevention of the disease or to influence the structure or function of the human body.
The second category is the inactive content or it is also called an excipient. This inactive content functions as a medium or a transportation agent to deliver or facilitate active content to work.
Inactive content will not increase or enhance the therapeutic effect of active content.
Some examples of this inactive content include binders, stabilizers, preservatives, dyestuffs, and Flavorizer.
The content and composition of Xolair are:
Xolair is used for patients who are indicative of asthma.
Dosage & How to use Xolair
Xolair is a drug that belongs to the hard drug group so that each purchase must use a doctor’s prescription. In addition, the dose of use of Xolair should also be consulted with the doctor first before use, because the dose of use varies depending on the severity of the disease suffered.
Older Persons & teen ≥ 12 years: 150-375 mg subcutaneously (through the skin) for 12-16 weeks. The maximum recommended dose: 375 mg every 2 of the week.
Xolair Side Effects
Side effects are an unwanted effect of a medication. These side effects may vary by individual depending on the condition of the disease, age, body weight, gender, ethnicity, or the health condition of a person.
The most common side effects seen with Xolair in patients aged 12 years and over (seen between 1 and 10 patients in 100) are headaches and reactions at the injection site, including swelling, erythema (redness), pain and itching.
In children aged between six and 12 years, the most common side effects (seen in more than one in 10 patients) are headaches and pyrexia (fever). For a complete list of all side effects reported with Xolair, see the Package Leaflet.
The possible Xolair side effects are:
- Injection site reactions,
- Upper abdominal pain,
- Upper respiratory tract infections & upper respiratory infections due to viruses,
- Sinusitis & headaches due to sinus,
- Pain in externality & musculoskeletal pain.
Those are not a complete list of side effects and others may occur. Contact your doctor for medical advice about side effects. You can report any side effects to the FDA at 1-800-FDA-1088
Xolair should not be used in people who may be hypersensitive (allergic) to omalizumab or other substances in the drug.
Get emergency medical help if you have any signs of allergic reactions:
- Anxiety or fear, feelings like you may faint;
- Blush (warmth, redness, or tinged feeling);
- Chest tightness, wheezing, cough, short breath, difficult breathing;
- Rapid or weak heartbeat; Or
- Swelling of your face, lips, tongue, or throat.
Contact your doctor at once if you have:
- Difficulty breathing;
- Numbness or tingling in your arms or legs;
- Fever, muscle aches, and rashes within days of receiving injections;
- Heart Attack Symptoms – pain or the highest pressure, pain spreads to your jaw or shoulders; Or
- Signs of blood clots, numbness or weakness, problems with vision or speech, blood up cough, swelling or redness in the arms or legs.
Why is Xolair approved?
The The Committee for Medicinal Products for Human Use (CHMP) concluded that, in general, the pattern of results was found in studies conducted with Xolair which showed its effectiveness in treating severe allergic asthma.
Therefore the Committee decided that Xolair’s benefits outweigh its risks as an adjunct therapy to improve asthma control in patients over six years old with persistent severe allergic asthma. The Committee recommends that Xolair be given marketing permission.
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