Pseudoxanthoma Elasticum: Angioid Streaks
The radiating from the optic disc are called angioid streaks, present in 85% of patients with Pseudoxanthoma elasticum. They signify breaks in Bruch's membrane, an elastic strip that separates retina from choroid. Angioid streaks are important for two reasons:
Therefore, these patients must undergo periodic ophthalmologic examinations. In between, they should be warned to consult an ophthalmologist immediately if they notice sudden blurring or warping of their vision.
- They help identify the systemic disease.
- They are a warning that new blood vessels may grow into the macula, bleed, and blind.
Angioid streaks also occur in Ehlers-Danlos syndrome, sickling disorders, and Paget's disease.