Sometimes the results obtained in the laboratory do not translate to the real world of the human body. For example, this week, a report published in the journal, Virulence discussed thapsigargin (TG), a molecule found in the thapsia plant, also known as deadly carrots. These plants are found in the western Mediterranean.
https://www.sciencealert.com/molecule-found-in-poisonous-plant-blocks-all-sars-cov-2-variants-in-cell-cultures?fbclid=IwAR3Ho23bW8FDSnzdZCanDKHf6lakJz1WmRzXxmclzeu8zurWdjgCx0iSXXo. TG has been tested in laboratories and found to be effective in destroying many viruses. Could TG be effective against coronavirus? https://www.mdpi.com/1999-4915/13/2/234
Yes, based on a study done nearly a year ago. Our COVID-19 vaccines attempt to prepare the body to see the virus as it enters our body. When this happens, immediate action can be taken by our immune system to combat the invading virus (or bacteria or fungus).
Results of TG Testing and Coronavirus
https://www.tandfonline.com/doi/full/10.1080/21505594.2021.2006960. Test results show that TB can block the many combinations of coronavirus – single and multi-variant viruses. TG does not prevent the virus from entering the host but disrupts the replication process once the virus begins to set up home and expand operations in the host’s body.
TG effectively destroyed the reproduction cycle of Alpha, Beta, Alpha/Beta, Alpha/Delta, and Beta/Delta variants of COVID-19. Previously, TG also disrupted the growth of other viruses – influenza, respiratory syncytial virus, and other coronaviruses.
Power of Delta!
https://www.cdc.gov/coronavirus/2019-ncov/variants/delta-variant.html and https://www.yalemedicine.org/news/5-things-to-know-delta-variant-covid. The Delta variant not only spreads faster than other variants, but it also causes the faster distribution of other variants when a person has more than one infection – e.g., Alpha and Delta, Beta and Delta variants.
The Alpha variant spreads four times faster when the Delta variant is present also. Transmission of the Beta variant is nine times faster in the presence of the Delta variant. TG shuts down all currently known variants of COVID-19. The Delta variant acts as a booster for other COVID-19 variants.
TG Clinical Trials
https://www.cancer.gov/about-cancer/treatment/clinical-trials/search/v?id=NCI-2014-00435. TG is currently in clinical trials to evaluate efficacy in treating various types of cancer. Based on the study published in Virulence, clinical studies are being discussed.
Antivirals worked far better than anyone would ever imagine in shutting down the spread of the Delta variant in India earlier this year. Without access to enough vaccines, India used an antiviral to halt the explosion of Delta in five weeks.
Before Delta, their death rate from coronavirus was under 100/day. A couple of weeks after Delta entered the picture, and COVID-19 deaths rocketed upward to over 35,000/day. Using an antiviral drug as a treatment resulted in COVID-19 deaths under 100/day in just over 30 days.
Effective vaccines might work to stop the spread of COVID-19. However, the hope promised with the mRNA vaccines expires after six months. When I think of a vaccine, I think of longer-term protection than six months. Antivirals might be the real answer for conquering the global pandemic.
Live Longer & Enjoy Life! – Red O’Laughlin – RedOLaughlin.com