Today is World Diabetes Day, represented by the blue ring symbol. This daily doodle features the three main tissues involved in carbohydrate metabolism: hepatocytes (liver cells), adipocytes (fat cells) and muscle. The blue ring also represents insulin, one of the hormones involved in glucose regulation. Insulin is produced by the pancreas and it has several acute effects based on the tissue type:
In muscle: glucose is stored as glycogen
In adipocytes: glucose may be stored as fat (glycolysis provides glycerol for triglyceride synthesis)
In liver: stimulation of glycogen synthesis and glycolysis and inhibition of glycogenolysis and gluconeogenesis.
Lectures: 1. Hormonal Regulation of Carbohydrate Metabolism 2. Pathogenesis of Type 1 and Type 2 Diabetes Mellitus