Genetic engineering is the genetic make-up of an organism’s genome using biotechnology tools and the one of the most powerful and promising application of the genetic engineering involves the treatment of genetic disorders like sickle cell anemia, Duchenne muscular dystrophy, cystis fibrosis, Tay-Sachs disease, Huntington’s chorea and Lesch-Nyhan syndrome. Now, medical Scientists can identify more than 3000 disorders happens because of the error in individuals DNA. By this technique scientists modify the genome of an organism. Creation of genetically modified organisms requires recombinant DNA. Recombinant DNA is a combination of DNA from different organisms or different locations in a given genome that would not normally be found in nature. The goal is to add one or more new traits that are not already found in that organism. Examples of genetically engineered organisms currently on the market include plants with resistance to some insects, plants that can tolerate herbicides, and crops with modified oil content.